Clinical trials: Adolescent Behavior, open to volunteers
Physical Activity, Childhood Obesity
The LEADS Trial (Linking Exericise for Advancing Daily Stress Management)
Chronic stressors have wide-reaching harmful effects on the physical, social, and psychological well-being of many African American (AA) families.
- Trial name
- LEADS (NCT07176234)
- Testing
- Treatment, Health Education
- Where
- 2 sites in United States
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- University of South Carolina
Heart Defects, Congenital, Cardiovascular Disease Other
Congenital Heart Disease Physical Activity Lifestyle Study V.2
The Congenital Heart Disease Physical Activity Lifestyle Intervention Study (CHD-PALS) V.2 seeks to determine the efficacy of a lifestyle intervention program for adolescents and young adults (AYAs) with congenital heart disease…
- Trial name
- CHD-PALS V2 (NCT06003023)
- Testing
- Physical Activity Monitoring, Tailored Exercise Prescription, Healthy Lifestyle Education
- Where
- United States
- Volunteers
- 144 people
- Sponsor
- Jamie Jackson
Obsessive-Compulsive Disorder (OCD)
OCD Summer Treatment Program for Adolescents in Iceland
The aim of the study is to examine the effectiveness of OCD treatment delivered in a group format for adolescents during a two week intensive summer treatment program.
- Trial name
- OCDtreatment (NCT07465354)
- Testing
- Intensive cognitive-behavioral treatment with exposure / response prevention
- Where
- Iceland
- Volunteers
- 70 people
- Sponsor
- University of Iceland
Adolescence
Exercise Facilitation of Adolescent Fear Extinction, Frontolimbic Circuitry, and Endocannabinoids
Anxiety disorders commonly begin during adolescence, and are characterized by deficits in the ability to inhibit or extinguish pathological fear.
- Trial name
- BRAINS (NCT06297278)
- Testing
- Moderate Intensity Exercise
- Where
- United States
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- Wayne State University
E Cigarette Use
Circuit Breathing Exercise on Smoking Cessation Among Youth E-Cigarette Users
This study aims to investigate the acute effects of a circuit breathing intervention on nicotine withdrawal symptoms and respiratory parameters among youth who use e-cigarettes.
- Trial name
- NCT07886099
- Testing
- Circuit breathing, Diaphragmatic Breathing, Normal Breathing Condition
- Where
- Thailand
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Chulalongkorn University
Opioid Use Disorder
Expanding the Youth Opioid Recovery Support (YORS) Intervention for MOUD Adherence to Adolescents With OUD
Despite rising rates of fatal opioid overdoses in the United States, adolescents with OUD are far less likely than adults to receive and be retained on medication for opioid use disorder (MOUD).
- Trial name
- YORS (NCT06774248)
- Testing
- Youth Opioid Recovery Support (YORS)
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Potomac Health Foundations
Depression, Sequestra
Sequenced Treatment Alternatives to Relieve Adolescent Depression (STAR-AD)
This project aims to investigate the effectiveness of existing common antidepressants and to provide new evidence for depressed children and adolescents who are not responding to their first treatment.
- Trial name
- STAR-AD (NCT05814640)
- Testing
- Fluoxetine, Sertraline, Vortioxetine
- Where
- China
- Volunteers
- 520 people
- Sponsor
- First Affiliated Hospital of Chongqing Medical University
Genetic Syndrome
I-TOPS With Patients With Genetic Syndrome SYN-TOPS
Genetic syndromes involving the central nervous system are often associated with cognitive, behavioral and communication difficulties that negatively impact adaptive functioning and quality of life.
- Trial name
- SYN-TOPS (NCT07563218)
- Testing
- Italian Tailored Online Problem-Solving (I-TOPS)
- Where
- Italy
- Volunteers
- 42 people
- Sponsor
- IRCCS Eugenio Medea
Childhood Depression
Neural Mechanisms of Family-Focused Treatment for Youth Depression
The goal of this interventional study is to compare the baseline neural mechanisms and parenting in depressed and non-depressed children and to examine baseline neural mechanisms and parenting as predictors of Family-Focused…
- Trial name
- NCT06289010
- Testing
- Family-Focused Treatment for Childhood-Depression (FFT-CD)
- Where
- 2 sites in United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Boston University Charles River Campus
Internet Gaming Disorder, Internet Addiction
Neurotrophic Factors, Impulsivity, and Reward Sensitivity in Children With Internet Gaming Disorder
Research and knowledge regarding the neurobiology of behavioral addictions and Internet Gaming Disorder (IGD) remain limited compared to substance and alcohol use disorders.
- Trial name
- NCT07590180
- Testing
- Clinical Evaluation and Biochemical Sampling
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Istanbul Saglik Bilimleri University
Caregiver Burden, Family Characteristics
Youth Mental Health Recovery in the Family After Inpatient Stay
The goal of this longitudinal mixed-methods study is to investigate caregiver strain, family processes and health outcomes after youth psychiatric inpatient treatment.
- Conditions
- Caregiver Burden, Family Characteristics, Parent-Child Interactions
- Trial name
- ReCoVer (NCT06865573)
- Volunteers
- 70 people
- Sponsor
- University of Vienna
Major Depressive Disorder (MDD), Suicidal Ideation
Accelerated Intermittent Theta Burst Stimulation for Adolescent and Young Adult Depression With Elevated Suicide Risk
The goal of this clinical trial is to learn if a fast-acting brain stimulation treatment called transcranial magnetic stimulation (TMS) can help people with depression and suicidal thoughts.
- Trial name
- NCT07025720
- Testing
- TMS
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of California, Davis
Healthy, Condom Use
Nen ŨnkUmbi/EdaHiYedo Plus (We Are Here Now Plus): a Multi-level Intervention to Reduce Health Disparities Among American Indian Youth
We Are Here Now - Plus (NE+) is a holistic, culturally centered, and multilevel intervention for American Indian youth to improve sexual health, mental health, and substance use outcomes.
- Conditions
- Healthy, Condom Use, Mental Health, Substance Use (Drugs, Alcohol)
- Trial name
- NE+ (NCT07460973)
- Testing
- NE+, Control
- Where
- United States
- Volunteers
- 843 people, healthy volunteers welcome
- Sponsor
- Montana State University
Anxiety
Grow With Grit: A School Nurse-Led SBIRT Pilot for Early Anxiety Detection
All enrolled students and their parents or guardians will complete baseline anxiety questionnaires. Students with a positive baseline screen will receive a brief school nurse-delivered coping skill, referral support when…
- Trial name
- GwG (NCT07766785)
- Testing
- Grow with Grit
- Where
- 4 sites in United States
- Volunteers
- 60 people
- Sponsor
- McLaughlin Research Institute for Biomedical Sciences, Inc.
ADHD
Dual-target iTBS for Youth With ADHD
This study will employ accelerated intermittent theta burst stimulation (aiTBS) targeting two transcranial magnetic stimulation (TMS) sites: the right inferior frontal gyrus and left inferior parietal lobule.
- Trial name
- NCT07084649
- Testing
- TMS
- Where
- China
- Volunteers
- 15 people
- Sponsor
- Shanghai Mental Health Center
Depressive Disorder, Suicidal Ideas
Evaluation of the Efficacy and Safety of Subcutaneous Ketamine in the Treatment of Depressive Episode With Suicidal Ideation and/or Behavior in Adolescents
Evaluate the efficacy and safety of subcutaneous ketamine added to usual treatment in the management of depressive episodes with suicidal ideation or behavior in adolescent patients, compared to usual treatment added to placebo…
- Trial name
- NCT06957704
- Testing
- ketamine, Midazolam
- Volunteers
- 60 people
- Sponsor
- Federal University of São Paulo
Behavior, Health
Train Your Brain 2.0 - Improving Memory and Decision Making Among Youth
The goal of this clinical trial is to deliver a computer-based working memory training program to improve delay discounting (DD) and prevent substance misuse among at-risk adolescents in a traditionally underserved area.
- Trial name
- NCT06242704
- Testing
- Working Memory Training, Working Memory
- Where
- 2 sites in United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Wayne State University
Disasters, Disaster Preparedness
Effectiveness of an Audiovisual Disaster-Education Intervention on Disaster Risk Perception and Preparedness Belief Among Senior High-School Adolescents
This cluster-randomized controlled trial tests whether a short, standardized disaster-education video improves two psychological precursors of disaster preparedness among senior high-school students in a hazard-prone district of…
- Conditions
- Disasters, Disaster Preparedness, Health Behavior, Risk Perception
- Trial name
- DERAP (NCT07781527)
- Testing
- Audiovisual disaster-education module, Attention-matched general-health video
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Tanjungpura University
ADHD, PTSD
Trauma-adapted Yoga in Child & Adolescent Psychiatry.
The goal of this randomized clinical trial is to evaluate the efficacy of trauma-adapted yoga as a complementary intervention to care as usual in child and adolescents psychiatry clinics, in the population of adolescents with the…
- Conditions
- ADHD, PTSD, Quality of Life, Self-Control
- Trial name
- TAY-CAP (NCT06330779)
- Testing
- Trauma-adapted yoga
- Where
- Sweden
- Volunteers
- 180 people
- Sponsor
- University West, Sweden
Attention Deficit Hyperactivity Disorder (ADHD)
Improving ADHD Teen Driving - Virtual Reality
Teens with Attention-Deficit/Hyperactivity Disorder (ADHD) have high rates of negative driving outcomes, including motor vehicle crashes, which may be caused by visual inattention (i.e., looking away from the roadway to perform…
- Trial name
- NCT06960980
- Testing
- FOCAL+, VR-FOCAL+
- Where
- United States
- Volunteers
- 204 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati