Clinical trials: Adolescent Asthma
Asthma
SOLO-Symbicort® in the Treatment of Persistent Asthma in Adolescents & Adults
The purpose of this study is to compare Symbicort Single Inhaler treatment with the Best Conventional Practice in patients with persistent asthma
- Trial name
- NCT00238784
- Testing
- Budesonide/formoterol Turbuhaler
- Where
- 3 sites in Canada
- Volunteers
- 1,300 people
- Sponsor
- AstraZeneca
Asthma in Children
Effect of Fluticasone Furoate/Vilanterol on EIA in Adolescents
Exercise induced asthma (EIA) is common in adolescents. (Fluticasone furoate (FF)/Vilanterol (VI)) is a once daily inhaler with bronchodilator effect lasting 24 hours.
- Trial name
- EIA (NCT04750603)
- Testing
- Fluticasone furoate (FF)/Vilanterol (VI), Salbutamol
- Where
- Israel
- Volunteers
- 92 people
- Sponsor
- Rambam Health Care Campus
Asthma
Efficacy and Safety of 2 Doses of Tiotropium Respimat Compared to Placebo in Adolescents With Severe Persistent Asthma
The overall purpose of the trial is to evaluate efficacy and safety of tiotropium inhalation solution delivered via Respimat® inhaler (2.5 mcg and 5 mcg once daily) over 12 weeks, compared to placebo, as add-on controller therapy…
- Trial name
- NCT01277523
- Testing
- tiotropium high dose, tiotropium low dose
- Where
- 69 sites in United States, Argentina and 12 more
- Volunteers
- 392 people
- Sponsor
- Boehringer Ingelheim
Asthma
Study of Mometasone Furoate/Formoterol Fumarate (MF/F) Metered Dose Inhaler (MDI) in Adolescents & Adults With Persistent Asthma (P08212)
The purpose of this study is to assess the safety, tolerability \& effectiveness of 2 strengths of Mometasone Furoate/Formoterol Fumarate (MF/F) Metered Dose Inhaler (MDI) in the treatment of persistent asthma in adults \&…
- Trial name
- NCT01566149
- Testing
- Mometasone Furoate/Formoterol Fumarate (MF/F) 100/5 mcg MDI, Mometasone Furoate/Formoterol Fumarate (MF/F) 200/5 mcg MDI
- Volunteers
- 49 people
- Sponsor
- Organon and Co
Asthma in Children
Translating an Efficacious Illness Management Intervention for Youth With Asthma
The propose of the study is to test the effectiveness of Reach for Control (RFC) as compared to Michigan MATCH to improve asthma symptoms, asthma management and lung functioning and to decrease ED visits and admissions for youth…
- Trial name
- NCT03317977
- Testing
- Reach for Control, MATCH
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Wayne State University
Asthma
A Study of Inhaled AZD8630 in Adolescents With Asthma
The purpose of this study is to evaluate the pharmacokinetic (PK) profile, safety, tolerability, and immunogenicity of single inhaled dose of AZD8630 administered in adolescent participants with asthma as well as the safety and…
- Trial name
- APkITA (NCT07065331)
- Testing
- AZD8630, Dry powder inhaler
- Where
- 9 sites in United States
- Volunteers
- 10 people
- Sponsor
- AstraZeneca
Asthma
A Study to Evaluate the Efficacy and Safety of QVM149 (Indacaterol Acetate / Glycopyrronium Bromide / Mometasone Furoate) Versus Salmeterol Xinafoate/Fluticasone Propionate in Children From 12 Years to Less Than 18 Years of Age With Asthma.
The purpose of this study is to evaluate the efficacy and safety of indacaterol acetate / glycopyrronium bromide / mometasone furoate (QVM149) compared to salmeterol xinafoate / fluticasone propionate in children from 12 to less…
- Trial name
- NCT05776927
- Testing
- QVM149, Salmeterol Xinafoate / Fluticasone Propionate
- Where
- 22 sites in Argentina, France and 7 more
- Volunteers
- 188 people
- Sponsor
- Novartis Pharmaceuticals
Asthma in Children, Lung Function Decreased
Lung Function Variability in Children and Adolescents
Long-term variability analysis of peak expiratory flow (PEF) and forced expiratory volume in 1 s (FEV1) has been successfully used in research to predict the exacerbation of the disease in adult individuals with asthma.
- Trial name
- LUV (NCT04163146)
- Testing
- Measurements of PEF and FEV1
- Where
- Greece
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Patras
Asthma in Children
Study for Children & Adolescent With Severe Asthma With an Eosinophilic Phenotype Treated With Mepolizumab
Open label, observational cohort study conducted to collect demographics, clinical characteristics and outcome observational data from children (6-17 years) with a clinical diagnosis of severe asthma in 2 countries (Spain and…
- Trial name
- CASAM (NCT05139381)
- Testing
- Mepolizumab
- Where
- United Kingdom
- Volunteers
- 148 people
- Sponsor
- King's College Hospital NHS Trust
Asthma
New Version Pulmicort Turbuhaler USA Children
A comparison of the safety, efficacy and budesonide pharmacokinetics of the currently approved Pulmicort Turbuhaler with a new version of the inhaler, in children and adolescents who have asthma.
- Trial name
- NCT00642161
- Testing
- budesonide
- Volunteers
- 430 people
- Sponsor
- AstraZeneca
Asthma in Children, Transplantation
Digital Delivery of Person-centered Transitional Care
Advances in medical care have extended the life expectancy of individuals with congenital and pediatric-onset diseases, leading to an increased need for effective transition programs as these individuals move from pediatric to…
- Trial name
- DigiStep (NCT06823622)
- Testing
- Stepstones transition program
- Where
- 2 sites in Sweden
- Volunteers
- 100 people
- Sponsor
- Göteborg University
Asthma
Efficacy and Safety Study of Benralizumab in Adults and Adolescents Inadequately Controlled on Inhaled Corticosteroid Plus Long-acting β2 Agonist
The purpose of this study is to determine whether Benralizumab reduces the exacerbation rate in patients with a history of asthma exacerbations and uncontrolled asthma receiving ICS-LABA with or without oral corticosteroids and…
- Trial name
- NCT01914757
- Testing
- Benralizumab
- Where
- 214 sites in United States, Argentina and 9 more
- Volunteers
- 2,508 people
- Sponsor
- AstraZeneca
Uncontrolled Asthma
A Phase 3 Study to Evaluate the Efficacy and Safety of Tralokinumab in Adults and Adolescents With Uncontrolled Asthma
A 52-Week, Multicentre, Randomized, Double-Blind, Parallel Group, Placebo Controlled, Phase 3 Study to Evaluate the Efficacy and Safety of Tralokinumab in Adults and Adolescents with Asthma Inadequately Controlled on Inhaled…
- Trial name
- STRATOS1 (NCT02161757)
- Testing
- Tralokinumab
- Where
- 243 sites in United States, Argentina and 13 more
- Volunteers
- 1,207 people
- Sponsor
- AstraZeneca
Asthma in Children, Asthma
Improving Quality of Life for Teenagers With Asthma
BACKGROUND: Asthma is a long-term lung condition affecting 1 in 11 children and young people in the UK. Many teenagers have well controlled asthma, but a significant number continue to experience regular symptoms and asthma…
- Trial name
- IMPAQT (NCT06851715)
- Testing
- Clinic consultation focused on asthma self-management
- Where
- 2 sites in United Kingdom
- Volunteers
- 98 people
- Sponsor
- University Hospital Southampton NHS Foundation Trust
Asthma
Assessment of a Mobile Intervention to Increase Adherence to Asthma Medication Among Adolescents
The purpose of this study is to assess the use of a mobile health intervention to improve adherence to asthma medication among adolescents.
- Trial name
- NCT02426814
- Testing
- Inhaler sensor, Mobile application for asthma adherence
- Where
- United States
- Sponsor
- CoheroHealth
Asthma
A Clinical Study to Evaluate Symbicort Turbuhaler Used 'as Needed' in Adults and Adolescents With Asthma.
The purpose of this study is to test if Symbicort® (budesonide/formoterol) Turbuhaler® is effective in treating asthma when used 'as needed' in patients with milder asthma.
- Trial name
- SYGMA1 (NCT02149199)
- Testing
- budesonide bid + terbutaline 'as needed'
- Where
- 255 sites in Australia, Brazil and 16 more
- Volunteers
- 3,850 people
- Sponsor
- AstraZeneca
Asthma, Sleep
Sleep Quality in High School Students With Asthma
The overall goal of this project is to develop and to preliminarily validate a novel intervention to be delivered in the high school setting that integrates two evidence-based, school-based interventions for urban adolescents…
- Conditions
- Asthma, Sleep, Asthma in Children
- Trial name
- NCT03073187
- Where
- 2 sites in United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Columbia University
Asthma
Tailored Asthma Management for Urban Teens
The purpose of this project is to refine and further evaluate an online asthma management and education program for urban teenagers.
- Trial name
- Puff City (NCT00201058)
- Testing
- Tailored Web-based Asthma Management, Generic web-based asthma education
- Where
- United States
- Volunteers
- 450 people
- Sponsor
- Henry Ford Health System
Asthma
Observational Assessment of Baseline Asthma Control in African-American Children
To determine if baseline asthma control influences susceptibility to pollutant-induced health effects in African-American children with moderate-to-severe asthma.
- Trial name
- TeenAire (NCT01891630)
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of North Carolina, Chapel Hill
Asthma
Prevention of Asthma Exacerbations Using Dupilumab in Urban Children and Adolescents
This is a multi-center, double-blind, placebo-controlled, randomized trial of dupilumab adjunctive therapy for prevention of asthma exacerbations in urban children and adolescents with T2-high exacerbation-prone asthma.
- Trial name
- PANDA (NCT05347771)
- Testing
- Dupilumab
- Where
- 8 sites in United States
- Volunteers
- 240 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)