Clinical trials: Adjustment Disorder, active
Obstructive Sleep Apnea (OSA), Snoring
Effects of Frequency Adjustment in Functional Electrical Stimulation on Genioglossus Muscle Activity
This single-group interventional study investigates the safety and physiologic effects of functional electrical stimulation (FES) applied to the tongue and submental muscles in adults at high risk for sleep apnea.
- Trial name
- NCT07466888
- Testing
- Functional Electrical Stimulation Device
- Where
- South Korea
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Seoul National University Bundang Hospital
Breast Cancer Risk, Cardiovascular Disease Risk
The RISC Registry--Risk Informed Screening Registry
Chronic diseases such as heart disease, cancer, and diabetes are the leading causes of death and disability in the United States. Six in ten adults have one chronic disease; 4 in 10 have two or more.
- Conditions
- Breast Cancer Risk, Cardiovascular Disease Risk, Cardiometabolic Risk, Diabetes
- Trial name
- RISC (NCT05848856)
- Testing
- Breast Cancer, Cardiometabolic, Cardiovascular Risk Screening and Follow up
- Where
- United States
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Precision Health Equity Initiative
Solid Tumor (Excluding CNS)
Effect of a Driving Pressure Adjustment Procedure for High-Frequency Jet Ventilation in Patients Undergoing Tumor Thermal Ablation in Interventional Radiology
Tumor thermal ablation under Jet Ventilation is a procedure performed under general anesthesia that enables tumor ablation under radiological imaging guidance.
- Trial name
- Pulmojet 3 (NCT07408375)
- Testing
- High-Frequency Jet Ventilation (HFJV)
- Where
- 7 sites in France
- Volunteers
- 560 people
- Sponsor
- Nantes University Hospital
Gout, Inflammatory Rheumatism
Treat-to-target by Email During Urate-lowering Therapy in Gout
Gout is secondary to urate crystal deposition after chronic elevation of serum urate level (SUL). Long-term lowering SUL below 360 µmol/L allows dissolution of deposited crystals and disease cure.
- Conditions
- Gout, Inflammatory Rheumatism, Hyperuricemia, Posology Adjustment
- Trial name
- GOUTEmail (NCT04733079)
- Testing
- Cleanweb electronic messaging ePro, Usual follow-up
- Where
- 2 sites in France
- Volunteers
- 204 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
SCHIZOPHRENIA 1 (Disorder), Psychosocial Adaptation
The Effects of a Solution-Focused Approach on Psychosocial Adjustment and Treatment Compliance in Individuals Diagnosed With Schizophrenia
The aim of this study is to evaluate the effects of a solution-focused approach-based individual intervention on psychosocial adjustment and treatment adherence in individuals diagnosed with schizophrenia.
- Conditions
- SCHIZOPHRENIA 1 (Disorder), Psychosocial Adaptation, Treatment Adherence
- Trial name
- NCT07144592
- Testing
- solution-oriented approach program
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Muş Alparslan University
Mild Cognitive Impairment (MCI)
Mild Cognitive Impairment and Psychopathology
Mild Cognitive Impairment (MCI) is a condition characterized by cognitive deterioration greater than what is expected from normal aging, representing an important risk factor for the development of dementia.
- Trial name
- MIND (NCT07358962)
- Where
- Italy
- Volunteers
- 118 people
- Sponsor
- IRCCS Centro Neurolesi Bonino Pulejo
Prostate Cancer
Radiation Treatment of the Prostate That is Specially Adjusted for Each Person
A number of recent studies have successfully reduced the number of radiotherapy treatments used for prostate cancer from 39 daily treatments to as little as 5 treatments.
- Trial name
- NCT07578519
- Testing
- radiotherapy
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- AHS Cancer Control Alberta
Hypertension (HTN), Food Insecurity
Navigating Hypertension and Food Insecurity
This multi-site randomized controlled trial uses a community-based approach to evaluate a Food as Medicine program for Native Hawaiian and Pacific Islander (NHPI) adults in Hawaii who have high blood pressure and difficulty…
- Trial name
- NCT07544836
- Testing
- Produce Prescription Only, Community Health Worker navigated Produce Prescription
- Where
- 3 sites in United States
- Volunteers
- 250 people
- Sponsor
- University of Hawaii
Respiratory Failure, Mechanical Ventilation Complication
Ventilator-based Inspiratory Muscle Training for Patients With Respiratory Failure
This study will be conducted to compare the effectiveness of progressive inspiratory flow trigger sensitivity rising versus stepwise pressure support reduction as ventilator-based inspiratory muscle training methods on weaning…
- Trial name
- NCT07353814
- Testing
- adjustment of parameters on mechanical ventilation device, routine plan of weaning and Conventional Chest Physiotherapy
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Chronic Kidney Disease, Proteinuria
A Study to Learn More About How Well the Study Treatment Finerenone Works, How Safe it is, How it Moves Into, Through, and Out of the Body, and the Effects it Has on the Body When Taken With an ACE Inhibitor or Angiotensin Receptor Blocker in Children With Chronic Kidney Disease and Proteinuria
Researchers are looking for a better way to treat children who have chronic kidney disease (CKD), which is long-term kidney disease, and proteinuria, a condition in which a person´s kidneys leak protein into the urine.
- Trial name
- FIONA (NCT05196035)
- Testing
- Finerenone (Kerendia, BAY94-8862)
- Where
- 132 sites in United States, Argentina and 30 more
- Volunteers
- 219 people
- Sponsor
- Bayer
Eating Disorders, Anorexia Nervosa
Targeting Social Function in Anxiety and Eating Disorders
Social processing and cognition are often altered in patients with eating disorders. The goal of this clinical trial is to assess two different social therapeutic interventions -- one educational, one interactive -- for their…
- Conditions
- Eating Disorders, Anorexia Nervosa, Bulimia Nervosa, Atypical Anorexia Nervosa
- Trial name
- SF (NCT06198023)
- Testing
- Educational, Interactive
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Texas Southwestern Medical Center
Rare Diseases
A Longitudinal Study on Family Adaptation and Relationship Dynamics in Pediatric Rare Diseases
Rare diseases in children can affect not only the child's health but also the well-being and relationships within the entire family.
- Trial name
- FAIR (NCT07497581)
- Where
- Switzerland
- Volunteers
- 240 people
- Sponsor
- Markus A. Landolt
Juvenile Idiopathic Arthritis Associated Uveitis, Uveitis, Anterior
Adalimumab Dose Adjustment for Pediatric Uveitis Treatment Trial
The goal of this clinical trial is to learn whether children and young adults with well-controlled juvenile idiopathic arthritis (JIA)-associated uveitis or chronic anterior uveitis can safely take adalimumab (or biosimilar)…
- Trial name
- ADAPT (NCT07699107)
- Testing
- Adalimumab/Biosimilar
- Where
- 18 sites in United States, Italy and 1 more
- Volunteers
- 160 people
- Sponsor
- Nisha Acharya
To Examine the Effects of Mobile App Support Provided to Expectant Fathers, Based on Transition Theory, on Anxiety, Bonding With the Fetus, and Marital Harmony
MOBİLE APP SUPPORT BASED ON TRANSİTİON THEORY FOR EXPECTANT FATHERS
THİS STUDY; İS DESİGNED TO EXAMİNE THE EFFECTS OF A MOBİLE APPLİCATİON-DEVELOPED BASED ON TRANSİTİON THEORY-PROVİDED TO EXPECTANT FATHERS ON ANXİETY, FETAL BONDİNG, AND MARİTAL ADJUSTMENT.
- Trial name
- NCT07767045
- Testing
- Mobile app support
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 96 people
- Sponsor
- Ege University
Oxygen Deficiency, COPD Exacerbation
FreeDom: Innovative Strategy for the Management of COPD Exacerbations
The main objective of the study is to assess the "FreeDom" innovative strategy (FreeO2 at Domicile) to reduce hospitalization duration in patients with COPD exacerbation.
- Trial name
- NCT03396172
- Testing
- Control, FreeDom
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- Laval University
Preterm Infant
Clinical Impact of Non-invasive Neurally Adjusted Ventilatory Assist in Very Preterm Infants
This is a prospective observational study investigating the impact of NIV-NAVA on short-term clinical outcomes and long-term neurodevelopment in very preterm infants.
- Trial name
- NCT06786039
- Testing
- Non-invasive NAVA
- Where
- 2 sites in South Korea
- Volunteers
- 80 people
- Sponsor
- Korea University Anam Hospital
Lymphoma, DLBCL
Study of Tazemetostat in Newly Diagnosed Diffuse Large B Cell and Follicular Lymphoma Patients Treated by Chemiotherapy
Phase I of the study is designed to determine the recommended phase II dose (RP2D) for tazemetostat in patients treated with 8 cycles of R-CHOP 21.
- Conditions
- Lymphoma, DLBCL, Follicular Lymphoma
- Trial name
- Epi-RCHOP (NCT02889523)
- Testing
- Tazemetostat, Rituximab, Cyclophosphamide
- Where
- 31 sites in Belgium, France
- Volunteers
- 214 people
- Sponsor
- The Lymphoma Academic Research Organisation
Dental Caries, Dental Occlusion
Occlusal Impact of Hall Crowns in Primary Molars
Hall Technique is a non-invasive restorative approach for managing carious primary molars, increasingly used in pediatric dentistry due to its simplicity and patient tolerance.
- Conditions
- Dental Caries, Dental Occlusion, Pediatric Dentistry
- Trial name
- NCT07134114
- Testing
- Hall Technique
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ankara Yildirim Beyazıt University
Depression - Major Depressive Disorder, Adjustment Disorder
Health and Work Ability Following Inpatient Treatment for Stress-related Disorders - Follow-up Study of the HARMODI Cohort
When treating stress-related conditions, it is important to understand how health and work ability develop over the long term. In our research project, we aim, firstly, to investigate how health and work ability develop over the…
- Conditions
- Depression - Major Depressive Disorder, Adjustment Disorder, Burnout Syndrome
- Trial name
- NCT07757997
- Where
- 2 sites in Switzerland
- Volunteers
- 143 people
- Sponsor
- Clinica Holistica Engiadina
OA Knee, TKA
Comparison of Functional Recovery Between Restricted Inverse Kinematic Alignment and Adjusted Mechanical Alignment With Robotic-assisted Unilateral Total Knee Arthroplasty.
The goal of this clinical trial is to learn if restricted inverse kinematic alignment total knee arthroplasty (restricted iKA TKA) improves functional recovery compared to adjusted mechanical alignment total knee arthroplasty…
- Trial name
- NCT06835621
- Testing
- Restricted inverse kinematic alignment Total Knee Arthroplasty, Adjusted Mechanical alignment Total Knee Arthroplasty
- Where
- 2 sites in Thailand
- Volunteers
- 80 people
- Sponsor
- Thammasat University