Clinical trials: Adenomyosis of Uterus
Adenomyosis
Risk Factors Associated With the Progression of Adenomyosis
Adenomyosis is a gynaecological disorder with a high prevalence in women of childbearing age and is characterised by the presence of endometrial glands and stroma within the myometrium, associated or not with hypertrophy and…
- Trial name
- NCT06718088
- Where
- Italy
- Volunteers
- 258 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Uterine Adenomyosis
Efficacy of Uterine Artery Embolization (UAE) in Management of Symptomatic Uterine Adenomyosis
Aim of the work: Evaluating the efficiency of uterine artery embolization as a minimally invasive method of treatment in management of symptomatic women with uterine adenomyosis
- Trial name
- NCT06652945
- Testing
- Uterine artery embolization
- Volunteers
- 30 people
- Sponsor
- Assiut University
Abnormal Uterine Bleeding Due to Adenomyosis (Disorder)
Radiofrequency Endometrial Ablation or Uterine Artery Embolization for Treatment of Adenomyosis-related Abnormal Uterine Bleeding
The present study aims to compare the efficacy (menstrual blood loss, pain, quality of life) and the safety (complications, recovery) of each conservative intervention (RFA, UAE) versus hysterectomy for the treatment of…
- Trial name
- ADENOTREAT (NCT07195305)
- Testing
- Radiofrequency endometrial ablation, Uterine artery embolization, Hysterectomy
- Where
- 4 sites in France
- Volunteers
- 230 people
- Sponsor
- University Hospital, Bordeaux
Adenomyosis
Norwegian Adenomyosis Study II: Gene Expression Profiling of Adenomyosis
Adenomyosis is characterized by the appearance of endometrial cells in the muscular layer of the uterus. It affects about 15-20% of the female population.
- Trial name
- NAPPED II (NCT02197923)
- Testing
- Myometrial biopsy, endometrial biopsy
- Where
- Norway
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Abnormal Uterine Bleeding, Unspecified, Benign Gynecological Disease
The Learning Curve of a Gynecology and Obstetrics Resident Performing Vaginal Natural Orifice Transluminal Endoscopic Surgery (V-NOTES) Hysterectomy in a University Hospital
This prospective observational study aims to evaluate the learning curve of obstetrics and gynecology residents performing Vaginal Natural Orifice Transluminal Endoscopic Surgery (V-NOTES) hysterectomy in a university hospital…
- Conditions
- Abnormal Uterine Bleeding, Unspecified, Benign Gynecological Disease, Adenomyosis of Uterus, Uterine Leiomyomas
- Trial name
- LC of V-NOTES (NCT07465822)
- Where
- Turkey (Türkiye)
- Volunteers
- 19 people
- Sponsor
- Cukurova University
Fibroid, Adenomyosis
Oxytocin in MRI-HIFU
Capability of oxytocin in improving the efficacy of MRI-HIFU is studied. Patients undergoing MRI-HIFU treatment are given oxytocin during treatment and the efficacy of the treatment will be analysed by patient reported symptom…
- Trial name
- NCT03937401
- Testing
- Oxytocin
- Where
- Finland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Turku University Hospital
Adenomyosis, Endometrial Cancer
Multi-omics Study on the Pathogenesis of Malignant Transformation of Adenomyosis
This study is to explore the driving genes and the molecular mechanism of malignant transformation of adenomyosis. This study acquired the formalin fixed paraffin-embedded (FFPE) tissue of patients pathologically conformed…
- Conditions
- Adenomyosis, Endometrial Cancer, Ectopic Endometrial Tissue, Eutopic Endometrium
- Trial name
- NCT04010487
- Testing
- whole exome sequencing and RNA-sequencing
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Lei Li
Endometriosis, Adenomyosis
Comparison of the Operation and Medical Treatment of Endometriosis and Adenomyosis
Endometriosis (including adenomyosis) is one of the most common gynecological diseases among women of childbearing age. Common symptoms such as menstrual pain, excessive menstrual flow, infertility, chronic lower abdominal pain…
- Trial name
- NCT03778359
- Testing
- Leuprorelin, Levonorgestrel, Dienogest
- Where
- Taiwan
- Volunteers
- 5,000 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Adenomyosis
Role of Dienogest in the Treatment of Patient With Symptomatic Adenomyosis
Adenomyosis was first described as endometrial glands in the myometrium of the uterus. The current definition of adenomyosis is provided in 1972 'the benign invasion of endometrium into the myometrium, producing a diffusely…
- Trial name
- NCT03654144
- Testing
- Dienogest, Combined Oral Contraceptive
- Volunteers
- 100 people
- Sponsor
- Assiut University
Adenomyosis, IVF
Ambispective Study to Assess the Effect of Pretreatment With a Levonorgestrel-Releasing Intrauterine System Versus Oral Progestin
The study participants' relevant medical records will be collected and reviewed for the retrospective subjects and after obtaining informed consent for the prospective subjects.
- Trial name
- NCT05152667
- Testing
- levonorgestrel-releasing intrauterine device (LNG-IUS)
- Where
- Egypt
- Volunteers
- 354 people
- Sponsor
- Wael Elbanna Clinic
Uterine Bleeding, Uterine Fibroids
What Are we Missing? Diagnosing Uterine Adenomyosis Using Ultrasound Elastography
To improve the clinical care of women with pelvic pain and abnormal uterine bleeding due to benign uterine conditions including leiomyomas (uterine fibroids) and adenomyosis by evaluating the accuracy of radiology diagnostic…
- Conditions
- Uterine Bleeding, Uterine Fibroids, Adenomyosis
- Trial name
- NCT01992718
- Testing
- Evaluation of MRI, US for pelvic and uterine conditions, Patient preference between MRI and Ultrasound
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- University of Michigan
Endometriosis
Evaluation of Endometrial Stromal Cell Apoptosis in Adenomyosis
Our previous results revealed that the expression of killer inhibitory receptors (KIRs) on NK cells was decreased in eutopic endometrium in women with adenomyosis.
- Trial name
- NCT00172588
- Where
- Taiwan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Pelvic Pain Syndrome, Endometriosis
The Good Pain Consultation in Endometriosis.
This PhD project investigates the effect of "the good pain consultation" and early integration of biopsychosocial pain education with current standard management of endometriosis.
- Conditions
- Pelvic Pain Syndrome, Endometriosis, Dysmenorrhea, Adenomyosis
- Trial name
- NCT07205614
- Testing
- pain consultation, biopsychosocial pain education + usual care, Usual Care
- Where
- Norway
- Volunteers
- 110 people
- Sponsor
- Sorlandet Hospital HF
Adenomyosis, Leiomyoma
New Inflammation Markers for Distinguishing Uterine Adenomyosis and Leiomyoma
Both pelvic masses and preoperative diagnosis of them have still continued as an important investigation subject. It is important to discriminate the diagnoses of leiomyoma and adenomyosis before operation especially among…
- Conditions
- Adenomyosis, Leiomyoma, Inflammation
- Trial name
- NCT02997787
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Kayseri Education and Research Hospital
Uterine Myomas, Adenomyosis
Single-port Access Laparoscopic-assisted Vaginal Hysterectomy
Minimally invasive surgery has become the standard treatment for many gynecologic disease processes. In the last decade, numerous studies have demonstrated that laparoscopic approaches to various gynecologic oncology…
- Trial name
- NCT01048931
- Testing
- single-port LAVH
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Adenomyosis
Impact of Ultra-long Versus Long Down-regulation Protocol on IVF/ICSI in Adenomyosis
Adenomyosis is a benign condition defined as the invasion of ectopic endometrium into the myometrium, resulting in smooth muscle hyperplasia and endometrial inflammation, commonly associated with endometriosis and uterine…
- Trial name
- ADENOFIV (NCT03940807)
- Testing
- 11.25mg GnRH agonist, 0.1 mg GnRH agonist, 25 µg transdermal oestradiol
- Where
- 14 sites in France
- Sponsor
- University Hospital, Toulouse
Cervical Cancer, Ovarian Tumor
The Application of Real-Time Near-infrared Imaging in Gynecological Surgery
Removing in situ and metastasis lesions completely during gynecological surgery is central to reduce the recurrence and death, and the identification of lesions in traditional gynecological surgery often depends on the experience…
- Conditions
- Cervical Cancer, Ovarian Tumor, Endometrial Carcinoma, Uterine Myomatosis
- Trial name
- NCT04224467
- Testing
- Intravenous ICG and Real-Time Near-infrared Imaging
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Chen Chunlin
Uterine Fibroids, Adenomyosis
Treatment of Benign Uterine Disorders Using High Intensity Focused Ultrasound (MR-HIFU)
MRI-guided high intensity focused ultrasound (MRI-HIFU) has been proven to be a safe and effective method in treating uterine fibroids and also adenomyosis.
- Trial name
- NCT02914704
- Testing
- MRI-HIFU
- Where
- Finland
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Turku University Hospital
Adenomyosis, Heavy Uterine Bleeding
Effect of Ulipristal Acetate on Bleeding Patterns and Dysmenorrhea in Women With Adenomyosis
Adenomyosis affects approximately 21% of symptomatic women who present to gynecology clinics. The disease is characterized by heavy bleeding and pain during periods.
- Conditions
- Adenomyosis, Heavy Uterine Bleeding, Dysmenorrhea
- Trial name
- NCT03325868
- Testing
- Ulipristal Acetate
- Where
- United States
- Sponsor
- Vanderbilt University Medical Center
Adenomyosis, Abnormal Uterine Bleeding
Adenomyosis: Genomic Mechanisms and Biological Response
Examination of genomic and biologic responses to LNG-IUS in patients with adenomyosis.
- Trial name
- NCT03428854
- Testing
- LNG-IUS
- Sponsor
- University of Texas Southwestern Medical Center