Clinical trials: Adenoma Detection Rate
Bowel Preparation for Colonoscopy
Efficacy, Safety and Tolerability of Magnesium Sulfate With Low-volume Polyethylene Glycol for Colonoscopy Cleansing
Magnesium salts such as magnesium citrate are often combined with polyethylene glycol to make the intestinal preparation before colonoscopy, which has shown high cleaning efficacy.
- Trial name
- NCT06728839
- Testing
- 1L PEG + 50g magnesium sulfate, 3L PEG, 4L PEG
- Volunteers
- 1,329 people, healthy volunteers welcome
- Sponsor
- Changhai Hospital
Colorectal Neoplasms, Adenoma Detection Rate
Impact of Proximal Colon Retroflexion in Colorectal Cancer Screening Programme
Colorectal cancer (CRC) is the most common tumor and the second leading cause of death in the Western world. The decrease in incidence and mortality by CRC in the population undergoing screening has been observed.
- Trial name
- NCT03041532
- Testing
- Proximal retroflexion, Frontal view
- Where
- Spain
- Volunteers
- 692 people
- Sponsor
- Hospital del Rio Hortega
Polyp and Adenoma Detection During Colonoscopy
Polyp Detection Rate After Single Oral Dose of Methylene Blue MMX Modified Release Tablets Administered to Subjects Undergoing Outpatients Colonoscopy
Polyp detection rate in colonoscopy following oral administration of MMX methylene blue tablets
- Trial name
- NCT01520337
- Testing
- oral tablet dye for detection of polyps during colonoscopy
- Volunteers
- 170 people
- Sponsor
- Cosmo Technologies Ltd
Adenoma Detection Rate
A Multicenter Study Evaluating the Effectiveness of Endo.Angel in Improving the Quality of Colonoscopy
Colonoscopy is a key technique in the detection and diagnosis of lower gastrointestinal diseases. High quality endoscopy results in better disease outcomes.
- Trial name
- NCT04102631
- Testing
- colonoscopy with assistance of Endo.Angel, colonoscopy without assistance of Endo.Angel
- Where
- China
- Volunteers
- 1,076 people, healthy volunteers welcome
- Sponsor
- Renmin Hospital of Wuhan University
Colorectal Adenoma
Development and Validation of an Artificial Intelligence-assisted System for Bowel Cleanliness Assessment Based on Withdrawal Distance Weighting
To address the limitations of current AI-based systems that rely on the assumption of a "constant withdrawal speed," this study proposes the integration of the UPD-3 endoscopic positioning system.
- Trial name
- NCT07150130
- Testing
- No Intervention: Observational Cohort
- Where
- China
- Volunteers
- 700 people
- Sponsor
- Fudan University
Adenoma Detection Rate
Artificial Intelligence-assisted Colonoscopy With or Without Endocuff Vision
Adenoma detection rate (ADR) is considered the single most important quality measure in colonoscopy and a higher ADR can reduce the risk of interval colorectal cancer (CRC).
- Trial name
- NCT05863208
- Testing
- Artificial intelligence, Endocuff vision, High-definition endoscope
- Where
- Taiwan
- Volunteers
- 1,000 people
- Sponsor
- E-DA Hospital
Colonic Polyp
Trainee Participation Increases Colon Adenoma Detection Rate
Previous studies that examined whether the presence of an additional observer, more specifically a GI fellow, during colonoscopy can enhance detection of all polyps and adenomas yielded conflicting results.
- Trial name
- ADR (NCT03908229)
- Testing
- Trainee colonoscopy, Experienced physician colonoscopy
- Where
- 4 sites in Italy
- Volunteers
- 812 people
- Sponsor
- Ospedali Riuniti di Foggia
Bowel Preparation Scale, Adenoma Detection Rate
Impact of Reinforced Education by Wechat and Short Message Service on the Quality of Bowel Preparation
High quality bowel preparation is essential for successful colonoscopy. This study aimed to assess the impact of reinforced education by Wechat or short message service (SMS) on the quality of bowel preparation.
- Trial name
- NCT02832869
- Testing
- short message service based re-education, Wechat based re-education
- Where
- China
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Changhai Hospital
Adenoma Detection Rate
Training Effects in Colonoscopy
Colon cancer is the second most common cause of death among cancer-related deaths in Germany. Precancerous lesions such as adenomas can be detected efficiently by colonoscopy.
- Trial name
- TraCo (NCT01786213)
- Where
- Germany
- Volunteers
- 3,500 people
- Sponsor
- Technical University of Munich
Colonic Adenoma, Colonic Polyp
Endocuff-assisted Colonoscopy vs Standard Colonoscopy on Adenoma Detection Rate
This is a prospective study comparing endocuff-assisted colonoscopy to standard colonoscopy. The goal of this study is to evaluate the interest of second-generation Endocuff Vision (ECV) to improve Adenoma detection rate and / or…
- Conditions
- Colonic Adenoma, Colonic Polyp, Colonoscopy
- Trial name
- Cuff-Bercy (NCT03344055)
- Testing
- Endocuff Vision (ECV) second generation
- Where
- France
- Volunteers
- 2,059 people
- Sponsor
- Société Française d'Endoscopie Digestive
Bowel Preparation Scale, the Amount of Air Bubble
Premedication Dyclonine Improves Visibility During Bowel Cleansing for Colonoscopy
In this randomized controlled study, consecutive outpatients scheduled for elective colonoscopy were randomized into two groups. Group A patients (n = 300) used only 3L PEG before colonoscopy.
- Conditions
- Bowel Preparation Scale, the Amount of Air Bubble, Adenoma Detection Rate
- Trial name
- NCT03352700
- Testing
- 3L PEG, 3L PEG+Dyclonine Hydrochloride Mucilage
- Where
- China
- Volunteers
- 580 people, healthy volunteers welcome
- Sponsor
- Changhai Hospital
Colorectal Cancer
Case Volume and Adenoma Rate During Screening Colonoscopy
Screening colonoscopy has been established as the most effective means of colorectal cancer prevention. This is based on the fact that colonoscopy detects and removes colonic polyps (adenomas) which are known to progress to…
- Trial name
- NCT00860665
- Where
- Germany
- Volunteers
- 12,134 people
- Sponsor
- Charite University, Berlin, Germany
Colon Adenoma, Colorectal Carcinoma
NBI Versus White Light Endoscopy for Optical Characterization of Neoplastic Polyps in the Colorectum
Adenomas, serrated adenomas and hyperplastic polyps are polypoid lesion in the colorectum. At the present moment, all polyps should be resected endoscopically, although only adenomas and serrated adenomas, but not hyperplastic…
- Conditions
- Colon Adenoma, Colorectal Carcinoma, Hyperplastic Polyp, Serrated Adenoma
- Trial name
- ADOPTION II (NCT03679429)
- Testing
- NBI Function
- Where
- 3 sites in Germany
- Volunteers
- 370 people
- Sponsor
- Technical University of Munich
Colonoscopy
Effect of Intraluminal Administration of Menthol Solution During Colonoscopy on Colonic Spasm and Adenoma Detection Rate
In recent years, with increasing research into antispasmodic agents, topical antispasmodics have attracted considerable attention due to their direct action on the gastrointestinal mucosa and relatively low incidence of adverse…
- Trial name
- NCT07501962
- Testing
- Endoscopic irrigation was performed using a 0.1% menthol solution combined with simethicone., Endoscopic irrigation was performed using an aqueous suspension prepared with simethicone and normal saline.
- Volunteers
- 440 people, healthy volunteers welcome
- Sponsor
- The First Affiliated Hospital of Zhengzhou University
Colon Adenoma, Colonoscopy
Adenoma Detection Rate in Water and Air Colonoscopy Using Computer-aided System
Water exchange (WE) is an effective insertion method to minimize insertion discomfort and maximize ADR. It is characterized by infusing water to guide insertion in an airless lumen with suctioning of infused water during…
- Trial name
- NCT05448300
- Testing
- Colonoscopy with water exchange or air insufflation methods
- Where
- 2 sites in United States, Taiwan
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Dalin Tzu Chi General Hospital
Colorectal Polyp
The Impact of Repeated Colonoscopic Insert Method on the Detection Rate of Adenomas in the Sigmoid Colon
Colorectal cancer (CRC) is a malignant tumour originating from the colorectal mucosal epithelium, with rising incidence and mortality rates.
- Trial name
- NCT06186778
- Testing
- secondary colonoscopy, conventional colonoscopy
- Where
- China
- Volunteers
- 650 people, healthy volunteers welcome
- Sponsor
- Jianning Yao
Colon Polyp, Colorectal Adenoma
9 Minutes for Tandem Colonoscopy Withdrawal
A mean withdrawal time of at least 6 minutes has been considered to be one of the critical quality criterions of colonoscopy. Recently, our group completed a multicenter randomized controlled trial, which proved that prolonging…
- Trial name
- NCT04797065
- Testing
- 6-minute then 9-minute withdrawal, 9-minute then 6-minute withdrawal
- Where
- China
- Volunteers
- 733 people
- Sponsor
- Changhai Hospital
Colon Cancer Screening, Colon Polyps
Comparison of Colon Adenoma Detection Rate Using Two Distal Colonoscope Attachments
The goal of this study is to compare two FDA approved distal colonoscope attachment devices, in order to identify which device can increase adenoma detection rate the most without increasing procedure time or risk.
- Conditions
- Colon Cancer Screening, Colon Polyps, Colon Adenomas, Water Exchange Colonoscopy
- Trial name
- NCT02665741
- Testing
- Olympus transparent cap, Medivators Endocuff, Control
- Where
- United States
- Volunteers
- 126 people
- Sponsor
- University of California, Davis
Adenoma Detection Rate
Comparison of Newer Colonoscopy Devices With Standard Forward Viewing (SFV) Colonoscopes in Daily Practice
Retrospective data analysis of comparsion of 3 types of colonoscopes in daily practice (FUSE Full spectrum colonoscopy with 330° angle of view vs Pentax standard HD-colonoscopes and Pentax plus Endocuff): medical device of the…
- Trial name
- NCT04472741
- Testing
- difference between colonoscopes
- Volunteers
- 4,114 people, healthy volunteers welcome
- Sponsor
- Gastroenterologie Baden-Wettingen
Colon Neoplasms
Full Spectrum vs. Standard Forward-viewing Colonoscopy
The aim of this study is to evaluate FUSE-colonoscopy in terms of feasibility and its possible additive contribution in the detection of important lesions, namely polyps and cancers, compared to the standard "forward-viewing"…
- Trial name
- NCT02117674
- Testing
- standard forward-viewing colonoscopy, full-spectrum colonoscopy, right colon retroflexion
- Where
- 2 sites in Greece
- Volunteers
- 246 people
- Sponsor
- Attikon Hospital