Clinical trials: Adenoma
Colorectal Adenoma
Establishment and Validation of a Predictive Model for the Risk of Colorectal Advanced Adenomas
The study aimed to analyze the risk factors of colorectal advanced adenoma and constructe a model to predict the high-risk individuals of harbouring colorectal advanced adenomas, so as to better identify screening participants…
- Trial name
- NCT05152082
- Where
- China
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Colon Polyp, Colon Adenoma
Prospective Evalulation of Artificial Intelligence-assisted Monitoring of Effective Withdrawal Time Versus Standard Withdrawal Time on Adenoma Detected Per Colonoscopy
The goal of this observational study is to assess the correlation between the artificial intelligence (AI) derived effective withdrawal time (EWT) during colonoscopy and endoscopists' adenoma per colonoscopy (APC), polyp per…
- Conditions
- Colon Polyp, Colon Adenoma, Artificial Intelligence
- Trial name
- NCT06345105
- Testing
- Endoscreener QC
- Where
- Hong Kong
- Volunteers
- 198 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Colorectal Cancer
Polyprev: Study to Compare Fecal Immunochemical Test With Endoscopic Surveillance After Advanced Adenoma Resection in Fecal Immunochemical Test Colorectal Cancer Screening Programs.
Colorectal cancer (CRC) screening programs have been implemented to reduce the burden of the disease. When an advanced colonic lesions is detected, it is recommended to perform endoscopic surveillance with different intervals…
- Trial name
- NCT04967183
- Testing
- Annual FIT, Endoscopic surveillance.
- Where
- Spain
- Volunteers
- 3,788 people, healthy volunteers welcome
- Sponsor
- Fundacin Biomedica Galicia Sur
Cancer
Post Market Evaluation of Aer-O-Scope Visualization
This will be a prospective multi-center, multi-national comparative non-blinded clinical investigation. Each subject will undergo back-to-back tandem colonoscopies with the Aer-O-Scope Colonoscope System and a conventional…
- Trial name
- NCT02926209
- Testing
- Aer-O-Scope (Colonoscopy), Colonoscopy (Conventional Colonoscope)
- Where
- 2 sites in United States, Israel
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- GI View Ltd.
Sessile Serrated Adenoma
Use of a Distal Colonoscope Attachment to Increase Detection of Sessile Serrated Adenomas
This study evaluates whether the use of a disposable colonoscope attachment, Endocuff Vision, can increase the detection of sessile serrated adenomas.
- Trial name
- NCT03560037
- Testing
- Endocuff Vision Assisted Colonoscopy
- Where
- United States
- Volunteers
- 427 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Mesothelioma, Lung Cancer
Early Detection of Lung Cancer and Mesothelioma in Workers Exposed to Asbestos
This is a pilot study that aims to develop a lung cancer screening program for workers in British Columbia, Canada exposed to asbestos who are at risk of developing lung cancer/pleural mesothelioma.
- Trial name
- NCT01719068
- Where
- Canada
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- British Columbia Cancer Agency
Dermatologic Disease
Personal Precise Treatment on Psoriasis and Psoriatic Arthritis
Part of psoriasis and psoriatic arthritis patients treated with biologics and met primary failure. Therefore, we are going to create a cell based platform to evaluate the treatment effects of different biologics on psoriasis and…
- Trial name
- NCT04915105
- Testing
- Markers data from PBMCs
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Taichung Veterans General Hospital
Colonoscopy Education
Comparing Clinical Performance of Novice Trainee Endoscopists Using Conventional Air Insufflation Versus Warm Water Infusion Colonoscopy
Hypothesis: Novice trainees will achieve significantly higher clinical competence and patient satisfaction scores with the use of warm water infusion method when compared with traditional air insufflation Primary outcome: adenoma…
- Trial name
- NCT01482546
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Colorectal Polyp, Colorectal Adenoma
Standard Colonoscopy Versus Colonoscopy With Endocuff Vision
This study seeks to compare colonoscopy results between a standard method and one using a distal scope attachment (Endocuff Vision).
- Conditions
- Colorectal Polyp, Colorectal Adenoma, Colon Cancer
- Trial name
- NCT03361917
- Testing
- Endocuff Vision
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Indiana University
Early Gastric Cancer, Gastric Adenoma
Magnifying Endoscopy With Narrow Band Imaging Versus Endoscopic Ultrasonography for Prediction of Tumor Invasion Depth in Early Gastric Cancer: A Prospective Comparative Study
The treatment of early gastric cancer can be divided into endoscopic resection and surgery, and the precise staging of early gastric cancer is very important to prevent unnecessary surgery or additional surgery after the…
- Conditions
- Early Gastric Cancer, Gastric Adenoma, Gastric Dysplasia
- Trial name
- NCT03546257
- Testing
- magnifying endoscopy with narrow band imaging (ME-NBI)
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Polyps
Cap-fitted Colonoscopy: a Randomized, Tandem Colonoscopy Study of Adenoma Miss Rates
This is a test in which a thin, black, flexible tube with a lighting system on the end is passed through the anus, into the rectum, in order to examine the large bowel or intestine, also called the colon.
- Trial name
- NCT00577083
- Testing
- Cap-fitted colonoscopy
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Indiana University
Colon Polyps
A Prospective Trial of an Endoscopic Quality Improvement Project
Randomized prospective multi-site validation study.
- Trial name
- Equip 2 (NCT02325635)
- Testing
- Educational Training
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Colon Cancer
Screening and Risk Factors of Colon Neoplasia
The investigators propose a screening population-based study to systematically evaluate the accuracy and clinical relevance of sDNA testing as a potential alternative to colonoscopy screening.
- Trial name
- NCT01647776
- Testing
- Stool DNA Test, biopsies of rectal and colon mucosa, Questionnaires
- Where
- United States
- Volunteers
- 3,315 people, healthy volunteers welcome
- Sponsor
- Case Comprehensive Cancer Center
Colorectum
Prospective Trial of Metformin - Chemoprevention Role
The goal of this clinical research study is to learn if metformin extended release (ER) can prevent colonic adenomas from becoming cancerous. Metformin ER will be compared to a placebo.
- Trial name
- NCT01550900
- Testing
- Metformin ER
- Volunteers
- healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Pituitary Neoplasms, Prolactinoma
Interdisciplinary Pituitary Disorders Centre of Excellence: Assessment of Patient Education Tools
The purpose of this research study is to determine the utility of educational materials designed to inform patients of their pituitary condition, in an effort to assist the patients, families, and staff deal with pituitary…
- Conditions
- Pituitary Neoplasms, Prolactinoma, ACTH-Secreting Pituitary Adenoma, Gigantism
- Trial name
- NCT01775332
- Testing
- Educational Intervention
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
Colorectal Cancer, Colorectal Adenoma
Adenoma Detection Rate in Artificial Intelligence-assisted Colonoscopy
The goal of this quasi randomized multicenter controlled clinical trial (RCT) is to investigate whether a combined real time computer-aided polyp detection (CADe) and computer-aided polyp characterization (CADx) system (GI…
- Conditions
- Colorectal Cancer, Colorectal Adenoma, Colorectal Neoplasms
- Trial name
- NCT05740137
- Testing
- AI-assisted colonoscopy
- Where
- 4 sites in Denmark
- Volunteers
- 795 people, healthy volunteers welcome
- Sponsor
- Ismail Gögenur
Adenoma
The MORDIS Study Clinical Investigational Plan
To demonstrate the use of WavSTAT4 system during colonoscopy in identifying diminutive colorectal lesions (e.g. hyperplastic polyps) that can be resected and discarded (or even left in-situ) without adverse clinical impact.
- Trial name
- MORDIS (NCT01980134)
- Where
- 6 sites in Czechia, Denmark and 3 more
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- SpectraScience
Bowel Preparation Scale, Adenoma Detection Rate
Impact of Reinforced Education by Video on the Quality of Bowel Preparation
High quality bowel preparation is essential for successful colonoscopy. This study aimed to assess the impact of reinforced education by Video on the quality of bowel preparation.
- Trial name
- NCT03185299
- Testing
- Video, Standard preparation instructions
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Changhai Hospital
Colonic Adenomas
Comparison Between White Light Endoscopy and Bright Narrow Band Imaging in Diagnosis Colonic Adenomas.
Removal of colorectal adenomas prevents the occurence of colorectal cancers. The use of chromo-endoscopy has been shown to improve the detection of flat adenomas.
- Trial name
- WLEvB-NBI (NCT01737567)
- Testing
- Bright Narrow Band Imaging., White Light Endoscopy
- Where
- Australia
- Volunteers
- healthy volunteers welcome
- Sponsor
- Professor Michael Bourke
Adenoma Colon
Comparison of Colonoscopy Adenoma Detection Yield
A Prospective Randomized Comparison of colonoscopy Adenoma Detection Yield of (i) Standard Colonoscopy (SC), (ii) artificial intelligence (Discovery) aided colonoscopy, and (iii) artificial intelligence (Discovery) and…
- Trial name
- NCT05158725
- Testing
- Standard Colonoscopy, Discovery aided colonoscopy, Discovery and G-EYE
- Where
- Germany
- Volunteers
- 1,320 people, healthy volunteers welcome
- Sponsor
- Dr. Horst Schmidt Klinik GmbH