Clinical trials: Addictive Behaviors
Drug-withdrawal., Drug Abuse
Clinical Studies on the Therapeutic Effects of Mirtazapine on Drug-craving in Cocaine Addicts.
INTRODUCTION. One of the main problems of the treatment of cocaine-dependent patients is the high rate of relapses occurs within the first months after detoxification.
- Conditions
- Drug-withdrawal., Drug Abuse, Drug-induced Depressive State, AOD Craving
- Trial name
- MADC (NCT01949571)
- Testing
- Mirtazapine (REMERON, Schering-Plough-Organon)
- Where
- Mexico
- Volunteers
- 64 people
- Sponsor
- Instituto Nacional de Psiquiatría Dr. Ramón de la Fuente
Substance Withdrawal Syndrome, Opiate Addiction
Study to Evaluate the Exposures of Lofexidine and Its Major Metabolites in Subjects Seeking Buprenorphine Dose Reduction
The purpose of this study is to evaluate the relative exposures of lofexidine and its major metabolites in subjects seeking buprenorphine dose reduction.
- Conditions
- Substance Withdrawal Syndrome, Opiate Addiction, Opiate Dependence
- Trial name
- NCT02801357
- Testing
- lofexidine administration in subjects seeking buprenorphine dose reduction
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- USWM, LLC (dba US WorldMeds)
Opiate Addiction
Treatment Study Using Depot Naltrexone (1/6) Philadelphia Coord/Data Mgmt Site
The aim of this project is to conduct a multi-site effectiveness study to determine whether the addition of a monthly injection of depot naltrexone to treatment as usual (TAU) will significantly improve outcome in parolees and…
- Trial name
- NCT00781898
- Testing
- Depot naltrexone, Treatment as Usual (TAU)
- Where
- United States
- Volunteers
- 308 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Labor Pain
Intrathecal Clonidine Addiction for Combined Spinal Epidural Analgesia During Labor
The study aims to evaluate the impact of the addition of 20 mcg of intrathecal clonidine in combined spinalepidural for labor analgesia on the local anesthetic consumption, on labor performance and on maternal fetal well-being.
- Trial name
- ICA (NCT03018171)
- Testing
- Clonidine, Sufentanil
- Where
- Italy
- Volunteers
- 268 people
- Sponsor
- San Giovanni Calibita Fatebenefratelli Hospital
Behavior, Addictive, Cigarette Smoking
Practicing Self-Control Lowers the Risk of Smoking Lapse
The proposed study will investigate the role of self-control in smoking cessation and whether interventions that improve self-control can help reduce the risk of lapsing among smokers who wish to quit.
- Trial name
- NCT00349687
- Testing
- self-control practice
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University at Albany
Sexual Addiction
A Study of Gene Polymorphisms Associated With Specific Presentations of Sexual Addiction
The study is intended to identify gene polymorphisms significantly associated with specific behavioral- and preoccupation-typologies of sexual addiction, and to identify additional potential genetic markers of sexual addiction.
- Trial name
- NCT02844985
- Testing
- No Intervention
- Where
- 8 sites in United States
- Volunteers
- 2,000 people
- Sponsor
- American Foundation for Addiction Research
Substance Related Disorders
Effectiveness of a Training Program for Self-management of the Substance Addiction Consequences - a Study Protocol
The substance dependent population has many health needs in which it is necessary to invest in competent approaches with more evidence.
- Trial name
- ADSProgram (NCT05397925)
- Testing
- ADSProgram - Self management for substance dependence program, Treatment as usual - Regular nursing consultation on a medication-based program
- Where
- 2 sites in Portugal
- Volunteers
- 60 people
- Sponsor
- Nursing School of Lisbon
Substance Dependency, Addiction
Working Memory Training for Substance Dependent Individuals
Background: Substance abusers show impaired working memory (WM) functioning. Promising findings show training WM results in an improved working memory capacity (WMC) and a decrease of clinical symptoms in a range of disorders…
- Conditions
- Substance Dependency, Addiction, Anxiety, Depression
- Trial name
- NCT02119949
- Testing
- Working memory training
- Where
- Netherlands
- Volunteers
- 180 people
- Sponsor
- Erasmus Medical Center
Acute Post-operative Pain, Chronic Post Operative Pain
Duloxetine Impact on Postoperative Pain Control and Outcomes
1. Evaluate differences between patients taking Duloxetine or placebo following lateral lumbar interbody fusion for postoperative narcotic consumption. 2.
- Conditions
- Acute Post-operative Pain, Chronic Post Operative Pain, Narcotic Use, Opioid Use
- Trial name
- NCT05611749
- Testing
- Duloxetine 60 MG
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Scripps Health
Internet Addiction Prevention Among Higher Secondary School Students
Effect of TPB-Based Educational Intervention on Preventing Internet Addiction in Students
This quasi-experimental study evaluated a Theory of Planned Behavior-based educational intervention among higher secondary students in Kathmandu, Nepal.
- Trial name
- NCT07504978
- Testing
- Educational Intervention Package based on the Theory of Planned Behavior
- Where
- Nepal
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Manish Rajbanshi
HIV
Computer-Assisted HIV Prevention for Young Drug Users
In this study, the investigators are developing and evaluating an interactive, computer-assisted HIV, STD and disease prevention program for young substance abusers that incorporates effective components of both prevention…
- Trial name
- NCT00182585
- Testing
- computer-based HIV, STD & Hepatitis Education, educator-delivered HIV, STD and Hepatitis education
- Where
- 2 sites in United States
- Volunteers
- 56 people
- Sponsor
- National Development and Research Institutes, Inc.
Substance Use Disorders, Eating Disorders
Substance Use and Eating Disorders : Food Craving and Addiction Transfer
Substance Use Disorder (SUD) and Eating Disorders (ED) are severe and persistent disturbances that are associated with significant harm.
- Trial name
- SUED (NCT05315635)
- Testing
- Questionnaire
- Where
- France
- Volunteers
- 294 people
- Sponsor
- Centre Hospitalier Charles Perrens, Bordeaux
Drug Addiction
Importance of Drug User Detection
1. Identify the illicit drugs (morphine, cannabinoids, benzodiazepines, barbiturates, tramadol, cocaine, amphetamine, alcohol, synthetic cannabinoids). 2.
- Trial name
- NCT05803044
- Volunteers
- 200 people
- Sponsor
- Assiut University
Nicotine Dependence, Cigarettes
The Role of Nicotine Dose and Route of Delivery in Affecting Adoption of E-cigarettes and Reducing Exposure to Toxic Combustion Products
This study plans to investigate whether using electronic cigarettes (e-cigarettes) or skin patches containing nicotine affects switching from smoking conventional combustible (burning) cigarettes.
- Trial name
- ENDS-Switch (NCT03492463)
- Testing
- Nicotine patch, E-cigarettes, Non-nicotine e-cigarettes
- Where
- United States
- Volunteers
- 94 people
- Sponsor
- Duke University
Opioid-Related Disorders, Opioid Dependence
An Innovative Intervention for OUD Treatment
The Bridge Device (BD) is a neuromodulator medical device that has been cleared by the FDA for Opioid Use Disorder (OUD) treatment.
- Conditions
- Opioid-Related Disorders, Opioid Dependence, Opioid Addiction, Opioid Withdrawal
- Trial name
- Bridge (NCT04325659)
- Testing
- Bridge Device, Lofexidine
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Hypersexuality, Compulsive Sexual Behavior
Effectiveness of ACT for Problematic Chemsex
Investigation of the efficacy of Acceptance and Commitment Therapy (ACT) for the psychological treatment of problematic chemsex.
- Conditions
- Hypersexuality, Compulsive Sexual Behavior, Sexualized Drug Use (Chemsex)
- Trial name
- ChemACT (NCT06406296)
- Testing
- Acceptance and Commitment Therapy (ACT)
- Where
- Spain
- Volunteers
- 36 people
- Sponsor
- Universidad Europea de Madrid
Alcoholism, Child Abuse, Sexual
Group Therapies for Reducing HIV-risk Behavior in Women Who Have Survived Childhood Sexual Abuse
This study will evaluate the effectiveness of trauma-focused group therapy for reducing HIV-risk behavior and revictimization among adult women survivors of childhood sexual abuse (CSA).
- Conditions
- Alcoholism, Child Abuse, Sexual, Sexual Abuse, Sexual Behavior
- Trial name
- NCT00220597
- Testing
- Trauma-focused group therapy
- Where
- United States
- Volunteers
- 171 people, healthy volunteers welcome
- Sponsor
- Stanford University
Breast Feeding, Opioid-Related Disorders
Methadone Levels in Breast Milk of Women Taking Methadone for Opiate Addiction - 2
Methadone is a drug that offers significant therapeutic benefits to opiate dependent women who are pregnant. Currently, it is the treatment of choice for this group of people.
- Trial name
- NCT00218010
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- National Institute on Drug Abuse (NIDA)
Drug Abuse, Cocaine Dependence
Reward Processing in Cocaine Addiction
Background: Cocaine affects the brain's ability to process information. However, different people respond to cocaine in different ways, and differences in brain structure and function may affect how cocaine alters brain activity.
- Trial name
- NCT01036074
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- National Institute on Drug Abuse (NIDA)
Smoking, Smoking Cessation
Treating Caregivers Who Smoke at AFCH
The purpose of this research study is to 1) see if a smoking cessation program is something that caregivers will use while their child is hospitalized, 2) see if caregivers think this program is something we should institute…
- Trial name
- NCT06051474
- Testing
- Nicotine Replacement Product
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
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