Clinical trials: Acute Pancreatitis (AP)
Pancreatitis, Acute
Transversus Abdominis Plane Block in the Analgesia of Acute Pancreatitis
Background Severe abdominal pain is a hallmark of acute pancreatitis (AP). A control pain is often difficult. Transversus Abdominis Plane (TAP) block has been used in pain control in patients with exacerbation of chronic…
- Trial name
- TAPA (NCT04037449)
- Testing
- TAP block, Conventional analgesia
- Volunteers
- 44 people
- Sponsor
- Consorci Sanitari Integral
Chronic Pancreatitis, Acute Pancreatitis
Relationship of CP and AP
The present study aimed to determine the prevalence of AP attacks before the diagnosis of CP and further identified the potential associated factors for AP episodes.
- Trial name
- NCT04670705
- Testing
- patients' characteristics
- Volunteers
- 1,022 people
- Sponsor
- Changhai Hospital
Acute Pancreatitis (AP)
Endoscopic Pancreatic Duct Stent Placement Versus Conventional Approach in the Treatment of Early Phase Acute Pancreatitis
The planned multicenter randomized study is aimed to assess the efficacy and safety of endoscopic pancreatic duct stenting in adult patients with acute pancreatitis.
- Trial name
- NCT07093996
- Testing
- Endoscopic pancreatic duct stent placement, Conventional treatment of acute pancreatitis in early phase
- Where
- 7 sites in China, Russia
- Volunteers
- 200 people
- Sponsor
- Almazov National Medical Research Centre
Acute Pancreatitis (AP), Enhancing Enteral Nutrition Tolerance
Evaluating RELiZORB Use for the Treatment of Feeding Intolerance in Adults With Moderate to Severe Acute Pancreatitis
The goal of this study is to learn if Relizorb, a fat-digesting enzyme, can improve tolerance of tube feeds in adult patients with moderate to severe pancreatitis.
- Trial name
- NCT07583342
- Testing
- RELiZORB digestive enzyme (immobilized lipase) cartridge
- Where
- 5 sites in United States
- Volunteers
- 15 people
- Sponsor
- Northwell Health
Acute Pancreatitis (AP)
ENDoscopic Assessment in Acute PANcreatitis Study (ENDOPAN Study)
This is a prospective observational cohort study designed to evaluate early upper gastrointestinal endoscopic findings in adult patients hospitalized with acute pancreatitis.
- Trial name
- NCT07714850
- Where
- Poland
- Volunteers
- 200 people
- Sponsor
- Jan Kochanowski University
Acute Pancreatitis (AP), Vagus Nerve Stimulations
Effect of Transcutaneous Auricular Vagal Nerve Stimulation on Acute Pancreatitis
Acute pancreatitis (AP), characterized by the sudden onset of pancreatic inflammation, is a frequent gastrointestinal emergency. Early suppression of the inflammatory response is critical to mitigate disease progression.
- Trial name
- NCT06998784
- Testing
- taVNS
- Where
- 5 sites in China
- Volunteers
- 60 people
- Sponsor
- Air Force Military Medical University, China
Acute Pancreatitis (AP)
Neutrophil-Creatinine Index in Patients with Acute Pancreatitis: Assessment of Severity and Outcome
Acute pancreatitis is a disease that usually has a mild disease course. However, around 20-30% of the patients develop severe complications.
- Trial name
- NCT06828965
- Testing
- Neutrophil creatinine index
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Assiut University
Acute Pancreatitis (AP)
Heparin to Prevent Organ Failure in Acute Pancreatitis
This clinical trial is designed to evaluate whether adding a standard blood-thinning medication, Unfractionated Heparin, to standard hospital care can help prevent severe organ failure in patients admitted with acute…
- Trial name
- NCT07609771
- Testing
- Unfractionated heparin, Standard supportive care
- Where
- Pakistan
- Volunteers
- 100 people
- Sponsor
- Allied Hospital Faisalabad
Acute Pancreatitis (AP), Inflammatory Indices
Utilization of CBC-Derived Inflammatory Indices in Assessing Severity and Prognosis of Acute Pancreatitis.
Utilization of CBC-Derived Inflammatory Indices in Assessing Severity and Prognosis of Acute Pancreatitis.
- Trial name
- NCT07233551
- Testing
- CBC derived inflammatory indices
- Volunteers
- 100 people
- Sponsor
- Assiut University
Acute Pancreatitis (AP), Hypertriglyceridemia Acute Pancreatitis
Multicenter Prospective Cohort Study of Hypertriglyceridemia Acute Pancreatitis
Hypertriglyceridemia-associated acute pancreatitis (HTG-AP) is the second leading cause in China and is receiving increasing global attention.
- Trial name
- NCT06976099
- Where
- 12 sites in China
- Volunteers
- 1,000 people
- Sponsor
- Peking Union Medical College Hospital
Organ Dysfunction, Organ Support
Thoracic Epidural Analgesia for Acute Pancreatitis With Early Organ Dysfunction
Acute pancreatitis may cause early respiratory, cardiovascular, or renal dysfunction and may require intensive care and organ support.
- Conditions
- Organ Dysfunction, Organ Support, Acute Pancreatitis (AP)
- Trial name
- TEA-APOD (NCT07697690)
- Testing
- Thoracic Epidural Analgesia With Ropivacaine, conventional analgesia
- Volunteers
- 150 people
- Sponsor
- First People's Hospital of Chenzhou
Acute Pancreatitis (AP), Gallstone Pancreatitis
Pentoxifylline Treatment in Acute Pancreatitis (AP)
The purpose of this study was to determine the effects (good and bad) of giving a drug called pentoxifylline to patients with acute pancreatitis.
- Conditions
- Acute Pancreatitis (AP), Gallstone Pancreatitis, Alcoholic Pancreatitis, Trauma Acute Pancreatitis
- Trial name
- AP (NCT02487225)
- Testing
- Pentoxifylline
- Where
- United States
- Volunteers
- 83 people
- Sponsor
- Mayo Clinic
Acute Pancreatitis (AP)
A Trial of the Arctx Cool Catheter in Acute Pancreatitis
Researchers will compare people who get the ACC Set plus standard of care to people who get standard of care alone. This will show whether adding the ACC Set helps.
- Trial name
- CHILL-AP (NCT07698119)
- Testing
- Treatment, Control
- Volunteers
- 200 people
- Sponsor
- Arctx Medical, Inc.
Post ERCP Pancreatitis, Acute Pancreatitis (AP)
Cold Water Papillary Irrigation Plus Rectal NSAIDs vs Rectal NSAIDs Alone for Post-ERCP Pancreatitis (COLD)
Post-ERCP pancreatitis is the most frequent complication of endoscopic retrograde cholangiopancreatography (ERCP). Rectal non-steroidal anti-inflammatory drugs (NSAIDs) are the current standard prophylaxis.
- Trial name
- COLDHUVN (NCT07885852)
- Testing
- Cold water irrigation of the papilla, Rectal NSAID (diclofenac 100 mg)
- Where
- Spain
- Volunteers
- 250 people
- Sponsor
- University Hospital Virgen de las Nieves
Walled Off Pancreatic Necrosis, Acute Pancreatitis (AP)
Nasojejunal Feeding Versus Oral Feeding Following Endoscopic Drainage of Walled Off Pancreatic Necrosis
The goal of this randomized control trial is to assess whether nasojejunal feed is better than oral nutrition in patients who are undergoing endoscopic cystogastrostomy of walled off necrosis following acute pancreatitis.
- Conditions
- Walled Off Pancreatic Necrosis, Acute Pancreatitis (AP), Endoscopic Ultrasound-Guided Drainage
- Trial name
- NCT07395778
- Testing
- endoscopic ultrasonography guided cystogastrostomy
- Where
- India
- Volunteers
- 50 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Acute Pancreatitis (AP), Diabetes Mellitus
Endocrine and Exocrine Secretory Function Alterations After Moderately Severe and Severe Acute Pancreatitis
The goal of this observational study is to learn about post-acute pancreatitis diabetes mellitus (PPDM-A). The main questions it aims to answer are: 1.
- Trial name
- NCT06590935
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Shanghai Changzheng Hospital
Choledocholithiasis, Cholecystolithiasis
One-stage and Delayed Laparoscopic Cholecystectomy After Endoscopic Retrograde Cholangiopancreatography with Endoscopic Sphincterotomy in Cholecystocholedocholithiasis
In this study, it is planned to compare ERCP with ES + delayed LC in children, with one-stage LC + ERCP with ES in adults to confirm that ERCP with ES + delayed LC is more suitable for pediatric patients with…
- Conditions
- Choledocholithiasis, Cholecystolithiasis, Cholangiopancreatography, Endoscopic Retrograde, Laparoscopic Cholecystectomy
- Trial name
- NCT06676241
- Testing
- endoscopic retrograde cholangiopancreatography; laparoscopic cholecystectomy, endoscopic retrograde cholangiopancreatography;laparoscopic cholecystectomy
- Where
- Russia
- Volunteers
- 44 people
- Sponsor
- Moscow Regional Research and Clinical Institute (MONIKI)
Acute Pancreatitis (AP)
Methodist Acute Pancreatitis Protocol
The overall goal of this ongoing registry study is to optimize initial evaluation and treatment of patients with AP according to recommended guidelines, the Methodist Acute Pancreatitis Protocol (MAPP), which were implemented in…
- Trial name
- MAPP (NCT04214756)
- Testing
- Acute Pancreatitis
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Methodist Health System
Acute Pancreatitis (AP)
Stroke Volume-based Fluid Resuscitation in AP
The SUSTAIN Trial is a randomized control trial that allows for the control of aggressive hydration that is currently used in an inpatient setting, which can result is fluid overload in certain patients.
- Trial name
- SUSTAIN (NCT07756476)
- Testing
- Lactated Ringer's, Lactated Ringers Stroke Volume Based Dosing
- Where
- 2 sites in United States
- Volunteers
- 80 people
- Sponsor
- University of Southern California
Acute Pancreatitis (AP), Acute Pancreatic Fluid Collection
Dextran 40 Plus Ringer's Lactate Vs. Ringer's Lactate Alone for Fluid Resuscitation in Acute Pancreatitis
This clinical trial aims to learn if a combination of Dextran 40 and Ringer's lactate solution can improve fluid resuscitation in mild and moderate acute pancreatitis (AP) and prevent complications.
- Conditions
- Acute Pancreatitis (AP), Acute Pancreatic Fluid Collection, Fluid Resuscitation
- Trial name
- NCT06835023
- Testing
- Ringer lactate (RLS), Dextran+Ringer Lactat(D+RLS)
- Where
- Romania
- Volunteers
- 100 people
- Sponsor
- Satu Mare County Emergency Hospital