Clinical trials: Acute Aortic Dissection
Aortic Dissection
The Relationship Between ALDH2 and Aortic Dissection
The purpose of this study is to evaluate the impact of ALDH2 Glu504Lys polymorphism on aortic dissection.
- Trial name
- RALAD (NCT02630212)
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Qilu Hospital of Shandong University
Aortic Aneurysm, Aortic Dissection
Different Antihypertensive Drugs on Aortic Diseases
The goal of this observational study is to learn about the effect of different hypotensive drugs on the prognosis of postoperative aortic patients.
- Trial name
- DADAD (NCT06626607)
- Testing
- CCB use, non-CCB use
- Volunteers
- 704 people
- Sponsor
- Eighth Affiliated Hospital, Sun Yat-sen University
Complex Abdominal Aortic Aneurysm, Thoracoabdominal Aortic Aneurysm
CAAAs, TAAAs, Aortic Arch Aneurysms or Dissections With Fenestrated/Branched Stent Graft
The purpose of this study is to gather safety and effectiveness of the Zenith t-Branch and customized physician-specified stent-graft with a combination of fenestrations and/or branches to repair aortic aneurysm.
- Conditions
- Complex Abdominal Aortic Aneurysm, Thoracoabdominal Aortic Aneurysm, Aortic Arch Aneurysm, Aortic Arch Dissection
- Trial name
- NCT02089607
- Testing
- CAAA and TAAA Arm, Aortic Arch Aneurysm Arm
- Where
- 3 sites in United States
- Volunteers
- 760 people
- Sponsor
- Gustavo S Oderich
Aortic Dissection
Zenith® TXD Post-market Surveillance in Japan
The study is a post-market surveillance study required by Japanese Regulatory Authorities as a condition of approval
- Trial name
- NCT02663739
- Testing
- Zenith® TXD
- Where
- 27 sites in Japan
- Volunteers
- 57 people
- Sponsor
- Cook Group Incorporated
Acute Aortic Syndrome, Aortic Dissection Type A
Protective Effect of Thymosin α1 Against Negative Immune Dysregulation and Organ Dysfunction After Acute Aortic Dissection Surgery (PANDA II)
Systemic inflammatory response syndrome (SIRS) and multiple organ dysfunction syndrome (MODS) are the major causes of death in patients with acute aortic syndrome (AAS).
- Trial name
- PANDA (NCT05339529)
- Testing
- Thymosin Alpha1, 28A-Glycine-28B-L-Arginine-28C-L-Glutamic Acid-28D-L-Alanine-28E-L-Proline-28F-L-Alanine-28G-L-Asparagine-, Blank control
- Where
- 15 sites in China
- Volunteers
- 600 people
- Sponsor
- Nanjing Medical University
CAD - Coronary Artery Disease, CABG
Soft Foam Dressings for Pressure Injury Prevention of Cardiac Surgery
The purpose of this study is to evaluate whether the application of soft foam dressings can reduce the occurrence of surgery-related pressure injuries among patients undergoing cardiac surgery.
- Conditions
- CAD - Coronary Artery Disease, CABG, Valve Disease, Heart, Aortic Diseases
- Trial name
- NCT07379294
- Testing
- CONVAFoam Hydrofiber Dressing, Standard Pressure Injury Prevention Care
- Volunteers
- 80 people
- Sponsor
- Shih,Wen-Chi
Thoracic Aortic Dissection
Post-market Clinical Trial of the Dominus® Stent-Graft
Real-world clinical trial evidence post-market, evaluating the safety and efficacy of the Dominus® StentGraft Endoprosthesis in treating thoracic aortic diseases, following the Instructions for Use
- Trial name
- DominusPMCF (NCT06270537)
- Testing
- Stent-Graft Dominus® Endoprosthesis
- Where
- 3 sites in Brazil
- Volunteers
- 100 people
- Sponsor
- Braile Biomedica Ind. Com. e Repr. Ltda.
Aortic Dissection Type B
EndoVascular Aortic Dissection Early vs Delayed
This is a prospective, multicenter, non-inferior, parallel-controlled observational study. This study aims to compare clinical outcomes of endovascular treatment for acute high-risk type B aortic dissection in the acute phase…
- Trial name
- EVADE (NCT07143071)
- Testing
- Acute Phase, Subacute Phase
- Where
- China
- Volunteers
- 4,068 people
- Sponsor
- Shanghai Zhongshan Hospital
Aortic Dissection, Stroke
Neurological Complications and ICU Workload After Emergency Repair of Acute Type A Aortic Dissection
Single-center retrospective cohort at China Medical University Hospital (Taichung, Taiwan) using fully de-identified electronic health records.
- Conditions
- Aortic Dissection, Stroke, Paraplegia, AKI - Acute Kidney Injury
- Trial name
- ATAAD-ICU (NCT07167628)
- Where
- Taiwan
- Volunteers
- 274 people
- Sponsor
- China Medical University Hospital
Aortic Aneurysm, Aortic Dissection
A Novel Wire-Reinforced Fenestration of a Hybrid Frozen Elephant Trunk Device for Supra-Aortic Branch Vessel Stenting During Aortic Arch Replacement
The goal of this prospective, non-randomized trial is to determine the safety and technical success of a novel modification to a U.S.
- Conditions
- Aortic Aneurysm, Aortic Dissection, Penetrating Aortic Ulcer (PAU), Aortic Pseudoaneurysm
- Trial name
- SA-FET (NCT07885865)
- Testing
- Modified Supra-Aortic Frozen Elephant Trunk (SA-FET) Device
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Maryland, Baltimore
Acute Aortic Dissection
A Triple-branched Stent Graft for Aute Debakey Type I Dissection Surgery
Prospective, multicenter, randomized controlled clinical trial plan to evaluate the effectiveness and safety of intraoperative stent system in the treatment of acute type I aortic dissection
- Trial name
- NCT06492980
- Testing
- triple-branched stent graft
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Fujian Medical University
Acute Myocardial Infarction, Pulmonary Embolism
Retrospective Study of Acute Chest Pain in Extremely Critical Condition for More Than Ten Years
Acute non-traumatic chest pain is a common kind of symptom in extremely critical condition, with various pathogenesis and different level of risk . Chest pain in high risk takes 1/3 of that.
- Conditions
- Acute Myocardial Infarction, Pulmonary Embolism, Aortic Dissection
- Trial name
- RESPECT (NCT02837120)
- Where
- China
- Volunteers
- 7,000 people
- Sponsor
- Qilu Hospital of Shandong University
Aortic Dissection
A Real World Study on Fabulous® Thoracic Aortic Stent System for Stanford B Aortic Dissection
A multicenter, retrospective study to evaluate the real-world efficacy of the Fabulous thoracic aortic stent system in the treatment of Stanford Type B aortic dissection.
- Trial name
- NCT05965271
- Testing
- Fabulous Thoracic Aortic Stent System
- Where
- 7 sites in China
- Volunteers
- 260 people
- Sponsor
- Hangzhou Endonom Medtech Co., Ltd.
Aortic Dissection
Optimized Strategies for Malperfusion Syndrome
An investigator-initiated, randomized, multicenter, two-arm, open-label study of consecutive patients presenting with acute type A aortic dissection (ATAAD) and malperfusion syndrome (MPS).
- Trial name
- NCT06532838
- Testing
- Optimized treatment strategies, Traditional treatment strategies
- Where
- China
- Volunteers
- 236 people
- Sponsor
- Xiamen Cardiovascular Hospital, Xiamen University
Aortic Aneurysm and Dissection
MITAORTA - Role of Mitochondrial Dynamic in Aneurysm and Dissection of Ascending Thoracic Aorta
The main objective is to compare the mitochondrial dynamic between patients operated for aneurysm of ascending aorta or type A aortic dissection (AAD) or control group
- Trial name
- MITAORTA (NCT05434481)
- Testing
- Mitochondrial dynamic analysis in the aorta samples and metabolomic profiling in the aortic diseases
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Hospital, Angers
Aneurysm Thoracic, Dissection of Thoracic Aorta
Ankura™ TAA Stent Graft System Post-Market Clinical Follow-up Study
The purpose of this study is to collect clinical data on patient outcomes, evaluate the safety and performance of Ankura TAA Stent Graft System and Surpass Super Stiff Guidewire, and build clinical evidence for patients with…
- Trial name
- NCT05639569
- Testing
- Ankura™ TAA Stent Graft System
- Where
- 15 sites in Germany, Greece and 3 more
- Volunteers
- 147 people
- Sponsor
- Lifetech Scientific (Shenzhen) Co., Ltd.
Aortic Dissection
Effects of Intraoperative Hemoperfusion on Acute Kidney Injury After Aortic Dissection
Acute kidney injury (AKI) is a common and serious complication after aortic dissection (AD), and it is closely related to the inflammatory response associated with cardiopulmonary bypass.
- Trial name
- EIHPOAKIAD (NCT05331495)
- Testing
- Intraoperative Hemoperfusion
- Where
- China
- Volunteers
- 206 people
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Methylprednisolone, Glucocorticoid
Glucocorticoids for Post-operative Patients With Acute Type A Aortic Dissection (The GLAD Trial)
This study is designed to evaluate the effects of glucocorticoid(GC) on improving post-operative organ dysfunction in patients with acute type A aortic dissection(aTAAD).
- Conditions
- Methylprednisolone, Glucocorticoid, Aortic Dissection, Organ Dysfunction
- Trial name
- NCT05329740
- Testing
- Methylprednisolone Injection
- Where
- China
- Volunteers
- 212 people
- Sponsor
- Shanghai Zhongshan Hospital
Aortic Dissection
The Roles of Intraluminal Pressure and the Dilation of Tunica Media in the Development of Aortic Dissection
Aortic dissection is defined as the separation of aortic medial lamellae. It is unknown why some aortic dissection are limited in extent while other aortic dissection extend extensively.
- Trial name
- NCT03030521
- Testing
- the aortic delamination test
- Where
- China
- Volunteers
- 8 people
- Sponsor
- Wuhan Asia Heart Hospital
Acute Type A Aortic Dissection
Efficacy of Bilateral Modified Catheter Antegrade Cerebral Perfusion in Acute Type A Aortic Dissection Surgery
This retrospective cohort study aims to evaluate the efficacy of a Bilateral Modified Catheter Antegrade Cerebral Perfusion (Modified bACP) technique in acute Type A aortic dissection surgery.
- Trial name
- NCT06943716
- Testing
- Modified Catheter Antegrade Cerebral Perfusion (Modified bACP), Conventional Brain Perfusion
- Where
- Taiwan
- Volunteers
- 273 people
- Sponsor
- China Medical University Hospital