Clinical trials: Activity, Motor
Healthy
Effects of Urban Afforestation Activity on Mental Health
This single-group pretest-posttest clinical trial aims to evaluate the effects of a single-session afforestation activity on affect and vitality levels in a sample of young adults.
- Trial name
- NCT05362552
- Testing
- Urban Afforestation Program
- Where
- Spain
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- Universidad de Granada
Creatine, Exercise
Creatine and Resistance Training in Older Adults With Mild Cognitive Impairment
The goal of this 26-week trial is to learn if creatine supplementation and resistance training (i.e., weightlifting; exercise that increases muscle mass), alone and together, impact cognition, brain health, and physical function…
- Conditions
- Creatine, Exercise, Mild Cognitive Impairment (MCI)
- Trial name
- NCT06948149
- Testing
- Creatine monohydrate, Resistance training
- Where
- Canada
- Volunteers
- 140 people
- Sponsor
- Western University, Canada
Lower Urinary Tract Disorder
Pelvic Floor Muscle Activity, Respiratory Functions, Respiratory Muscle Strength, and Functional Capacity in Children With Lower Urinary Tract Dysfunction
The functional disorders of the lower urinary tract in children involve overactive bladder with thickening of the bladder muscle, resulting in a decrease in functional bladder volume and an increase in intra-bladder pressure.
- Trial name
- NCT06652178
- Where
- Turkey (Türkiye)
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Healthy Aging
Effect of Mindfulness on EEG Brain Activity for Cognitive and Psychological Well-being in the Elderly
As the worldwide population of older adults rapidly increases over the coming years, effective strategies are needed to help this population to maintain and enhance physical, cognitive, and psychological well-being.
- Trial name
- NCT05941143
- Testing
- mindfulness-based intervention
- Where
- Italy
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- IRCCS Centro San Giovanni di Dio Fatebenefratelli
Physical Inactivity
Intergenerational Behavioral Intervention to Enhance Physical Activity in Older Adults at Risk for Alzheimer's Disease
This is a four-week pilot randomized controlled trial of a behavioral intervention in older adults at risk for Alzheimer's disease. Older participants are a subgroup from the PREVENT-AD longitudinal cohort.
- Trial name
- HABS (NCT06038643)
- Testing
- Motivational behavioural intervention and daily activities monitoring, Active Control
- Where
- Canada
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Douglas Mental Health University Institute
Gait, Unsteady
At-home Walking Cadence Functional Assessment and Recovery Trajectory for Older Adults Undergoing Major Surgery
This is a prospective observational study looking at gait-cadence in older adults who are scheduled to have major abdominal surgery at the University of Chicago.
- Trial name
- CADENCE (NCT05886725)
- Testing
- Patients using Step Test Application and Accelerometer
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Chicago
Agitation Associated With, Alzheimer's Disease
A Phase 3, 12-week, Multicenter, Randomized, Double-blind, Placebo-controlled Trial to Evaluate the Efficacy, Safety, and Tolerability of 2 Fixed Doses of Brexpiprazole in the Treatment of Alzheimer's Agitation
To compare the efficacy of 2 fixed doses of brexpiprazole with placebo in participants with agitation associated with dementia of the Alzheimer's type.
- Conditions
- Agitation Associated With, Alzheimer's Disease, Alzheimer's Type, Mental Disorder
- Trial name
- NCT01862640
- Testing
- Brexpiprazole, OPC-34712
- Where
- 85 sites in United States, Croatia and 5 more
- Volunteers
- 433 people
- Sponsor
- Otsuka Pharmaceutical Development & Commercialization, Inc.
Obesity
The Impact of a Pre-Operative Exercise Program on Fitness Outcomes Following Bariatric Surgery
BACKGROUND: Obesity is a global epidemic and Canada has one of the highest obesity rates in westernized countries. Obesity has many health related complications, including high blood pressure, high cholesterol, diabetes, sleep…
- Trial name
- NCT02010489
- Testing
- 12 week Exercise Program
- Where
- Canada
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Athletic Injuries
Effects on In-Game Decision Making Processes
This study aims to investigate the effects of analytical thinking skills and reaction speed on performance in female football players.
- Trial name
- NCT06814691
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Istanbul Medipol University Hospital
Aortic Bioprosthesis Structural Valve Dysfunction
Assessment of Osteoblastic Activity With 18F-Fluoride in Aortic Bioprosthesis Structural Valve Dysfunction (SVD)
Structural valve dysfunction (SVD) is the most common and life threatening complication in patients treated by aortic valve replacement.
- Trial name
- TEP-SVD (NCT03015818)
- Testing
- 18F-Fluoride PET-CT ; CT calcium scoring ; 18F-FDG PET-CT
- Where
- France
- Volunteers
- 25 people
- Sponsor
- Nantes University Hospital
Prediabetes / Type 2 Diabetes, Sedentary Behaviors
Effects of Exercise Snacks on Clinical and Health Outcomes
Physical inactivity and prolonged sedentary behavior are major health concerns, especially for individuals with chronic conditions such as diabetes and prediabetes.
- Conditions
- Prediabetes / Type 2 Diabetes, Sedentary Behaviors, Physical Inactivity
- Trial name
- NCT07609290
- Testing
- Exercise Snacks
- Where
- Taiwan
- Volunteers
- 58 people
- Sponsor
- Chimei Medical Center
Obesity, Students
Improving Healthy Nutrition and Physical Activity Behaviors of University Students
There are many descriptive studies in the literature on health behaviors of university youth.However, there are a limited number of model-based interventional studies explaining the development of positive health behaviors of…
- Trial name
- NCT04195516
- Testing
- web based training,individual counseling, using reminders
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Istanbul Medipol University Hospital
Geriatric, Elderly
Validity and Reliability of the Exergame Enjoyment Questionnaire (EEQ) in Turkish
The aim of this research is to adapt the Exergame Enjoyment Questionnaire (EEQ) into Turkish and to evaluate its suitability for the Turkish elderly population through validity and reliability analyses.
- Trial name
- NCT07562906
- Testing
- Validity and reliability assessments
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
COPD, Depression
The Development of an Integrated Physical Activity and Mental Health Intervention for Veterans With COPD, Emotion Distress, and Low Physical Activity
Chronic Obstructive Pulmonary Disease (COPD) is prevalent and debilitating chronic disease in Veterans. COPD is highly co-morbid with depression and anxiety conferring greater morbidity and mortality risk.
- Conditions
- COPD, Depression, Anxiety
- Trial name
- NCT04953806
- Testing
- Step-CBT
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- VA Office of Research and Development
Active Aging Individuals Aged 65 and Over, Aging
Italian Validation of the dNA Scale and Its Correlation With Neurocognitive Variables
The goal of this experimental multicentric intervention study is to validate, in Italian, the dynamic Neurocognitive Adaptation (dNA) Scale, which has already been validated in English, among a healthy elderly population (aged 65…
- Conditions
- Active Aging Individuals Aged 65 and Over, Aging, Mild Cognitive Impairment (MCI), Dementia
- Trial name
- NCT07533084
- Where
- 8 sites in Italy
- Volunteers
- 265 people, healthy volunteers welcome
- Sponsor
- Neuromed IRCCS
Non Hodgkin Lymphoma, Diffuse Large B Cell Lymphoma
Safety, PK/PD, and Clinical Activity of KT-413 in Adult Patients with Relapsed or Refractory B-cell NHL
This Phase 1a/1b study will evaluate the safety, tolerability and the pharmacokinetics/ pharmacodynamics (PK/ PD) of KT-413 in patients with R/R NHL.
- Conditions
- Non Hodgkin Lymphoma, Diffuse Large B Cell Lymphoma, DLBCL, MYD88 Gene Mutation
- Trial name
- NCT05233033
- Testing
- KT-413
- Where
- 8 sites in United States, United Kingdom
- Volunteers
- 7 people
- Sponsor
- Kymera Therapeutics, Inc.
Multiple Sclerosis, Relapsing
Prospective Study to Assess Disease Activity and Biomarkers in Minority Participants With Relapsing Multiple Sclerosis (RMS) After Initiation and During Treatment With Ocrelizumab
Open-label, prospective, single-arm, multi-center study to assess disease activity and biomarker of neuronal damage in minority patients (self-identified Black or African American (AA) and Hispanic/Latino (HA) patients with…
- Trial name
- NCT04377555
- Testing
- Ocrelizumab
- Where
- 28 sites in United States, Kenya and 1 more
- Volunteers
- 179 people
- Sponsor
- Genentech, Inc.
Extranodal Natural Killer/T-Cell Lymphoma, Nasal Type, Classical Hodgkin Lymphoma
Allogeneic CD30.CAR-EBVSTs in Patients With Relapsed or Refractory CD30-Positive Lymphomas
This study involved patients that have a cancer called diffuse large B cell lymphoma (DLBCL), NK and T cell lymphomas (NK/TL) or classical Hodgkin lymphoma (cHL) (hereafter these 3 diseases will be referred to as lymphoma).
- Trial name
- NCT04288726
- Testing
- CD30.CAR-EBVST cells
- Where
- 2 sites in United States
- Volunteers
- 27 people
- Sponsor
- Baylor College of Medicine
Healthy
Increasing Physical Activity Levels in Low-Income Women
Regular physical activity is important for good health. Women, particularly women with low incomes, have many personal barriers to regular physical activity.
- Trial name
- NCT00065026
- Testing
- Physical activity opportunities for low-income women
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Autism Spectrum Disorder
Development and Validation of a System for the Anticipation of Challenging Behaviors
Most people with autism spectrum disorder (ASD) present at least one form of challenging behavior (CB). Self-injurious, aggressive, and disruptive CBs linked with social interaction, community-based service exclusion, and a life…
- Trial name
- NCT05340608
- Testing
- Smart, non-invasive shirt - Physiological parameters, Smart, non-invasive shirt - Relation with challenging behaviors, Smart, non-invasive shirt - Proof of Concept
- Where
- Israel
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Ariel University