Clinical trials: Acne Scars
Acne Vulgaris
Treatment of Acne Vulgaris Using NAFL in Combination With Isotretinoin and Pricking Blood Therapy
BACKGROUND Isotretinoin remains one of the first line medications for moderate-to-severe acne vulgaris (AV) but its side effect is a major concern for Asian patients.
- Trial name
- NCT04156815
- Testing
- 1,565nm NAFL, Oral isotretinoin, Pricking blood therapy
- Where
- China
- Volunteers
- 60 people
- Sponsor
- xjpfW
Acne Scars - Mixed Atrophic and Hypertrophic
Tripeptide/Hexapeptide Topical and Hybrid Laser Treatment for Acne Scarring
To evaluate the efficacy of a tripeptide/hexapeptide topical (Alastin Regenerating Skin Nectar with TriHex Technology®) in wound healing and scar reduction following Erbium:YAG hybrid resurfacing laser for acne scarring compared…
- Trial name
- NCT04606134
- Testing
- Hybrid fractional laser, Alastin Regenerating Skin Nectar with TriHex Technology, Cetaphil face cream
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Rochester
Atrophic Acne Scar
SkinPen Efficacy on Acne Scars on the Face and/or Back
This single-center, clinical trial will take place over a 90 day course followed by 1-month and 6-month post treatment visits to assess the efficacy and tolerability of the SkinPen device when used on both men and women on the…
- Trial name
- NCT02646917
- Testing
- Aesthetic Microneedling Treatment
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Bellus Medical, LLC
Acne Vulgaris, Atrophic Acne Scars
Adapalene 0.3% - Benzoyl Peroxide 2.5% Gel and Risk of Formation of Atrophic Acne Scars
This was a multi-centre, randomized, investigator blinded, vehicle controlled trial using intra-individual comparison (right half-face versus left half-face).
- Trial name
- OSCAR (NCT02735421)
- Testing
- ABPO Forte Gel, Vehicle gel
- Where
- 7 sites in Canada, France
- Volunteers
- 67 people
- Sponsor
- Galderma R&D
Photodamage, Irregular Pigmentation
Comparison of the RevLite Electro-optic Q-Switched Neodymium-doped Yttrium Aluminium Garnet (EO QS Nd:YAG) Laser to a Fractionated Laser System
The purpose of this study is to compare the results of treatment between the side of the face treated with the RevLite Laser and the side of the face treated with a fractionated laser system.
- Conditions
- Photodamage, Irregular Pigmentation, Acne Scars
- Trial name
- NCT00955461
- Testing
- RevLite laser treatment, Fractionated Laser treatment
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- ConBio, a Cynosure Company
Acne Scars
Clinical Evaluation of Fractional Radiofrequency for the Treatment of Acne Scarring
Prospective, single centre, evaluator-blind study of the safety and performance of fractional radiofrequency (RF) for the treatment and reduction of acne scarring.
- Trial name
- NCT03767153
- Testing
- Venus Viva
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Venus Concept
Atrophic Post Acne Scarring
Comparison Between Microneedling Daycare Procedure and Tazarotene 0.1% Gel Local Application in Acne Scarring
Post acne scarring is a common complication of acne. Cosmetic appearance of the post acne facial scarring can be improved by various methods. Among the procedural methods microneedling (1) is a novel and a promising option.
- Trial name
- NCT03170596
- Testing
- tazarotene gel 0.1%, Microneedling
- Where
- India
- Volunteers
- 36 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Acne Vulgaris
Treatment of Acne Scars With Erbium:Yttrium Aluminum Garnet (Er:YAG) Laser Examined Under OCT
This study is examining the effects of the 2940 nm Er:YAG on atrophic facial acne scars under optical coherence tomography in terms of blood flow, vessel shape, skin roughness, collagen content, and epidermal thickness.
- Trial name
- NCT03333759
- Testing
- Alma - Harmony XL Laser
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Miami
ATROPHIC ACNE SCARS
Comparison Of Outcome Of Microneedling With Autologous PRP Vs Microneedling With Topical Insulin In Treatment Of Post Acne Atrophic Scars.
Microneedling with topical INSULIN is a simple, effective tool for building body's new collagen layers and thus an alternative to all erosive techniques such as lasers, peels.
- Trial name
- NCT06002854
- Testing
- PRP( platelet rich plasma) and Insulin human
- Where
- Pakistan
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Jinnah Postgraduate Medical Centre
Acne Vulgaris, Acne Scars
Efficacy of Microneedling With Topical Vitamin C in Treatment of Acne Scarring
This study aimed to evaluate the efficacy of dermaroller and topical vitamin C- either separate or combined- in treatment of post acne scars.
- Trial name
- NCT03522922
- Testing
- Dermaroller, Topical Vitamin C
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Sohag University
Atrophic Scar
Clinical Benefits and Safety of Combined Polynucleotides and Hyaluronic Acid - Newest - for Acne Scars Treatment
This clinical study wants to evaluate the efficacy and safety of a medical device combining "Polynucleotide Highly Purified Technology" (PN-HPT™) and hyaluronic acid (Newest-Mastelli S.r.l) for treating moderate-to-severe…
- Trial name
- NCT05936437
- Testing
- Subjects treated with Newest medical device
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- Mastelli S.r.l
Wrinkles, Acne Scars
Epidermal Delivery of Ani-Aging Ingredients
To assess the safety and efficacy of an ablative fractional, 2940-nm laser combined with the US Impact and cosmetic -formulations for improving the appearance of wrinkles, acne scars and pigmented skin.
- Conditions
- Wrinkles, Acne Scars, Pigmentation
- Trial name
- NCT01847066
- Testing
- Erbium 2940 plus cosmetics plus Impact, Erbium 2940 plus cosmetics
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Alma Lasers Inc.
Acne Scars - Mixed Atrophic and Hypertrophic, Acne
Pilot Study Investigating the Efficacy of Fat Grafting as a Treatment for Male and Female Facial Acne Scarring
This single-center, clinical trial consists of a one autologous fat grafting treatment followed by 3-month and 6-month post-treatment visits in order to assess the efficacy of fat grafting when used by men and women with facial…
- Trial name
- NCT04559022
- Testing
- Fat Grafting
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Wrinkle, Acne Scars - Mixed Atrophic and Hypertrophic
Functional Usability and Feasibility Testing of the Profound Matrix™ System
This is a non-randomized, multi-center, open-label clinical trial evaluating the efficacy and clinical feasibility of the Profound Matrix device for electrocoagulation and for treatment of wrinkles and acne scars.
- Trial name
- NCT06192550
- Testing
- Profound Matrix™ System
- Where
- 5 sites in United States, Israel
- Volunteers
- 193 people, healthy volunteers welcome
- Sponsor
- Candela Corporation
Acne Scars, Acne Scars - Atrophic
Efficacy of Stromal Vascular Fraction on Acne Scar Correction
This study aims to evaluate the efficacy and safety of intradermal injection of autologous stromal vascular fraction (SVF) in the treatment of atrophic acne scars.
- Trial name
- NCT07094958
- Testing
- stromal vascular fraction (SVF), Normal Saline (NS)
- Volunteers
- 16 people
- Sponsor
- Seoul National University Hospital
Acne Vulgaris, Atrophic Acne Scar
Autologous Plasma Gel Injection Versus Polydioxanone Cog Threads Insertion for the Treatment of Atrophic Post-acne Scars: a Split-face
Both male and female patients, with atrophic acne scars All patients underwent one session of subcision before receiving: A: cog PDO threads on one side of the face (one session). B: plasma gel on the other side (one session).
- Trial name
- NCT06580691
- Testing
- Subcision plus Plasma gel injection Vs Subcision plus Cog PDO threads
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Sameh Sarsik
Acne, Scar
Comparison of Treatments for Atrophic Acne Scars
Acne scars have high prevalence, significant impact on quality of life and are a therapeutic challenge for dermatologists. Previous studies have shown promising results for the treatment of acne scars with non-ablative fractional…
- Trial name
- NCT02025088
- Testing
- Laser, Microneedling
- Where
- Brazil
- Volunteers
- 23 people
- Sponsor
- Thaís Hofmann Cachafeiro
Acne Scars
Laser Treatment of Acne Scars in Fitzpatrick Skin Types III-VI
The purpose of this study is to evaluate the RevLite Q-Switched Neodymium: Yttrium-Aluminum-Garnet (Nd:YAG) Laser in the treatment of acne scars in darker skin types (Fitzpatrick Skin Types III, IV, V and VI).
- Trial name
- NCT01221922
- Testing
- RevLite Q-Switched Nd:YAG Laser
- Where
- Thailand
- Volunteers
- 20 people
- Sponsor
- ConBio, a Cynosure Company
Atrophic Acne Scar
Use of Artefill® for Moderate to Severe Atrophic Acne Scar Correction
The purpose of this study is to determine whether Artefill is safe and effective for the correction of atrophic facial acne scars.
- Trial name
- NCT01559922
- Testing
- Normal Saline, Artefill
- Where
- 10 sites in United States
- Volunteers
- 175 people
- Sponsor
- Suneva Medical, Inc.
Atrophic Acne Scars
Comparison of Efficacy of Carbon Dioxide Laser With Subcision Versus Platelet-Rich Plasma Bio-Fillers With Subcision for the Treatment of Atrophic Acne
This randomized controlled trial compared two combined treatment approaches for atrophic acne scars. A total of 100 patients aged 15-45 years were enrolled from the Department of Dermatology, Lahore General Hospital, Lahore, and…
- Trial name
- NCT07752186
- Testing
- Platelet-Rich Plasma Bio-Filler With Subcision, Fractional Carbon Dioxide Laser With Subcision
- Where
- Pakistan
- Volunteers
- 100 people
- Sponsor
- Lahore General Hospital