Clinical trials: Absence
Full Spectrum
A Self-controlled Study of the Effect of Partial Spectral Absence of Visible Light on the Pupil
Previous studies have shown that the spectrum of light influences myopia. LED lights with a partially absent light spectrum increase the risk of myopia progression compared to LEDs with a full spectrum, potentially mediated by…
- Trial name
- NCT06501131
- Testing
- full-spectrum light exposure, specific spectrum absence light exposure
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Epilepsy, Absence
Objective EEG Bed Side Assessment of Impaired Conscious Awareness in Epilepsy
In this project EEG recordings between healthy participants and those with a diagnosed Absence-epilepsy will be compared. The investigators suggest differences in EEG microstate analysis and neuropsychological parameters related…
- Trial name
- NCT04799795
- Where
- Germany
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- University Hospital Schleswig-Holstein
Jaw, Edentulous, Partially, Acquired Absence of Single Tooth
Case Selection and Treatment Protocol for Immediate Dental Implants in the Esthetic Zone
In this study a tooth that needs to be extracted will be replaced by an implant (artificial root) placed at the same appointment as the extraction.
- Trial name
- NCT02154581
- Testing
- SLActive implant
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center at San Antonio
Colorectal Cancer, Lung Cancer
Safety of GM-CT-01 With and Without 5-Fluorouracil in Patients With Solid Tumors
This is a Phase I, multi-center study of GM-CT-01, which has been shown to increase the anti-tumor activity of 5-fluorouracil in mice.
- Conditions
- Colorectal Cancer, Lung Cancer, Breast Cancer, Head and Neck Cancer
- Trial name
- NCT00054977
- Testing
- GM-CT-01, 5-fluorouracil
- Where
- 4 sites in United States
- Volunteers
- 40 people
- Sponsor
- Galectin Therapeutics Inc.
Sick Leave
Effects of Motivational Interviewing for Long-term Sick Absence
Long-term sickness absence has considerable impact on social functioning, families involved, the employer, and society as a whole.
- Trial name
- NCT03212118
- Testing
- Treatment as usual (TAU-0), Structured talks (TAU-2), motivational interviewing (MI)
- Where
- Norway
- Volunteers
- 774 people
- Sponsor
- Norwegian University of Science and Technology
Upper GI Bleeding
Presence or Absence of Blood in the GI Lumen
Bleedings in the upper digestive tract are common. Usually, laboratory and clinical parameters are considered to establish a suspicion for a bleeding in the digestive tract and to estimate urgency of the situation.
- Trial name
- NCT05415124
- Testing
- HemoPill, Endoscopy
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- NYU Langone Health
Drop Out, Absence
A School-based Intervention Project to Increase Completion of Upper Secondary School in Norway
Drop out from upper secondary school represents a risk for the future health and wellbeing of young people. Strengthening of psychosocial aspects of the learning environment may be an effective strategy to promote completion of…
- Conditions
- Drop Out, Absence, Academic Achievement/Average Grade, Mental Health
- Trial name
- COMPLETE (NCT03382080)
- Testing
- Dream School Program, Mental Health Support Team
- Volunteers
- 3,500 people, healthy volunteers welcome
- Sponsor
- University of Bergen
Dental Anxiety, Children, Only
Effect of Parental Absence on Child's Dental Anxiety and Behaviors During Dental Treatment
The basis of pediatric dentistry is to provide cooperation in children with various behavioral management techniques. The presence or absence of the parent during dental treatments can be used to ensure the child's compliance…
- Conditions
- Dental Anxiety, Children, Only, Dental Caries
- Trial name
- NCT05125731
- Testing
- Parental absence, Parental visual support, Parental presence
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Ankara Yildirim Beyazıt University
Memory Disorder, Retention Disorder, Cognitive
Investigation of Memantine in the Treatment of Memory, Concentration or Attention Problems
In this study, memantine will be tested in a new indication: in the treatment of subjective memory, concentration, or attention problems (subjective cognitive impairment) in the absence of dementia.
- Conditions
- Memory Disorder, Retention Disorder, Cognitive, Subjective Cognitive Impairment, Memory, Concentration or Attention Problems
- Trial name
- NCT01261741
- Testing
- Memantine
- Where
- 14 sites in Germany, United Kingdom
- Volunteers
- 299 people
- Sponsor
- Merz Pharmaceuticals GmbH
Epilepsy, Absence
A Pilot Study of Topiramate in Childhood Absence Epilepsy
Limited data exist on the effectiveness of antiepileptic drugs for treatment of childhood absence epilepsy. Preliminary data suggest that topiramate may be an effective drug for this condition.
- Trial name
- NCT00210574
- Testing
- topiramate
- Volunteers
- 12 people
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Generalized Epilepsy
A Study to Determine if BHV-7000 is Effective and Safe in Adults With Idiopathic Generalized Epilepsy With Generalized Tonic-clonic Seizures
The purpose of this study is to determine whether BHV-7000 is effective in the treatment of idiopathic generalized epilepsy with generalized tonic-clonic seizures and includes an additional open-label extension (OLE) phase.
- Trial name
- SHINE (NCT06425159)
- Testing
- BHV-7000
- Where
- 109 sites in United States, Australia and 12 more
- Volunteers
- 27 people
- Sponsor
- Biohaven Therapeutics Ltd.
Musculoskeletal Disorder, Anxiety Disorders
A Naturalistic Trial of Nudging Clinicians in the Norwegian Sickness Absence Clinic. The NSAC Nudge Study
The Norwegian Sickness Absence Clinic (NSAC) Nudge Study is a naturalistic randomized controlled multicentre trial which aim is to measure the efficacy of nudging clinicians' attention towards patients' motivation for work…
- Conditions
- Musculoskeletal Disorder, Anxiety Disorders, Depression, Fatigue
- Trial name
- NSAC (NCT05006976)
- Testing
- NSAC health only, NSAC health + MBW
- Where
- 5 sites in Norway
- Volunteers
- 1,180 people
- Sponsor
- Nordlandssykehuset HF
Emotional Eating Behaviour
Inducing Children's Emotional Eating
Background: Children's emotional eating is related to greater BMI and less healthy diet but little is known about the early development of this behavior.
- Trial name
- NCT01122290
- Where
- United Kingdom
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University of Birmingham
Breast Cancer, Postsurgical Acquired Absence of Organ
Non-contrast Magnetic Resonance Angiography in Deep Inferior Epigastric Perforator Flap Breast Reconstruction Planning
The aim of this study is to evaluate the efficacy and safety of contrast-free magnetic resonance angiography (MRA) for deep inferior epigastric perforator flap planning.
- Trial name
- NCT06061835
- Testing
- Non-contrast MRA in preoperative perforator vessels mapping for deep inferior epigastric perforator (DIEP) flap breast reconstruction planning., CTA with iodine contrast in preoperative perforator vessels mapping for deep inferior epigastric perforator (DIEP) flap breast reconstruction planning.
- Where
- 2 sites in Russia
- Volunteers
- 135 people
- Sponsor
- I.M. Sechenov First Moscow State Medical University
Dilation, Pupil Reaction Absent
Efficacy of the MydCombi on Pupillary Dilation in Pediatric and Adult Patients
To raise the standard of care, improve the overall patient experience and streamline practice flow, Eyenovia has developed an innovative mydriatic to be delivered as a microdose by a specialized dispenser.
- Trial name
- NCT06366217
- Testing
- MydCombi Device, MydCombi Drug
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- University of California, San Francisco
Absence Epilepsy, Childhood, Absence Seizures
Detecting Absence Seizures Using Hyperventilation and Eye Movement Recordings
This study is being done to find out if a smartphone app can identify absence seizures. Children who have a history of absence seizures, as well as children without any seizure history, will be testing out the app.
- Conditions
- Absence Epilepsy, Childhood, Absence Seizures, Absence Epilepsy, Epilepsy in Children
- Trial name
- DASHER (NCT06093490)
- Testing
- Eysz Hyperventilation Recorder
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- Eysz, Inc.
Hearing Impaired Children
Auditory Steady State Response vsAuditory Brainstem Response
All children with hearing loss should have access to resources necessary to reach their maximum potential. The following principles provide the foundation for effective EHDI[Early Hearing Detection \& Intervention] systems and…
- Trial name
- NCT04040517
- Testing
- Evoked potential audiometer
- Volunteers
- 40 people
- Sponsor
- Assiut University
Dental Implant, Tooth Absence
Comparative Study of Immediate Single Unit Implants in Early Loading Protocols, With or Without Photobiomodulation.
Post-extraction implants are an alternative to traditional implant placement on completely healed bone, in order to reduce the number of surgical interventions, shorten treatment time, maintain bone architecture and thus provide…
- Conditions
- Dental Implant, Tooth Absence, Tooth Extraction
- Trial name
- NCT05106855
- Testing
- Low Laser Radiation, Changing the implant surface, Low Laser Radiation off
- Where
- Spain
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Santiago de Compostela
Long Term Sick Leave, Absent-mindedness
Joint Coordination to Facilitate the Transition From Sick Leave to Employment
GESAM is a randomized controlled intervention study that addressed women and men on long-term sick leave in Uppsala County. Participants which are on sick leave due to mental illness and/or pain and were expected to reach the…
- Trial name
- GESAM (NCT03348410)
- Testing
- Motivational interviewing
- Where
- Sweden
- Volunteers
- 193 people
- Sponsor
- Uppsala University
Adenosine Deaminase Deficiency, Autosomal Recessive Disorder
Total-Body Irradiation Followed By Cyclosporine and Mycophenolate Mofetil in Treating Patients With Severe Combined Immunodeficiency Undergoing Donor Bone Marrow Transplant
This pilot clinical trial studies total-body irradiation followed by cyclosporine and mycophenolate mofetil in treating patients with severe combined immunodeficiency (SCID) undergoing donor bone marrow transplant.
- Conditions
- Adenosine Deaminase Deficiency, Autosomal Recessive Disorder, Immune System Disorder, Purine-Nucleoside Phosphorylase Deficiency
- Trial name
- NCT00008450
- Testing
- Allogeneic Bone Marrow Transplantation, Cyclosporine, Laboratory Biomarker Analysis
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Fred Hutchinson Cancer Center