Clinical trials: Abscess, active
Brain Abscess, Cerebral Abscess
Partial Oral Antibiotic Treatment for Bacterial Brain Abscess
The investigators aim to determine if oral antibiotics are clinically acceptable as treatment of brain abscess. Following 2 weeks of standard intravenous antibiotic therapy, half of patients will continue with this treatment for…
- Trial name
- ORAL (NCT04140903)
- Testing
- Early transition to oral antibiotics, Standard treatment of intravenous antibiotics
- Where
- 4 sites in Denmark
- Volunteers
- 400 people
- Sponsor
- Henrik Nielsen
Appendiceal Abscess
Study of Management of Appendicular Abscess
This study aims to detect indications of surgical drainage after failure Ultrasound guided percutaneous drainage This study will include any male and female above 18 years old that presented with appendicular abscess Patients…
- Trial name
- NCT06718595
- Volunteers
- 100 people
- Sponsor
- Assiut University
Autoimmune Hepatitis, Primary Sclerosing Cholangitis
Liver-gut Axis Study Through Identification of Liver Disease-specific Microbiome
In this study, we aim to identify gut microbiomes specific to patients with chronic refractory liver disease and to conduct a gut-liver axis study on the pathogenesis and disease progression.
- Conditions
- Autoimmune Hepatitis, Primary Sclerosing Cholangitis, Non-Alcoholic Fatty Liver Disease, Liver Abscess
- Trial name
- LGAS (NCT06519162)
- Where
- South Korea
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Chungnam National University Hospital
Abdominal Abscess
Abdominal aBscess Catheter Sclerotherapy (ABCS)
This is a single center, two arm phase I/II clinical trial exploring the use of chemical sclerosants (ethanol and povidone iodine) in decreasing the time needed for catheter drainage for patients with non-fistulous intraabdominal…
- Trial name
- ABCS (NCT06906029)
- Testing
- Catheter Sclerotherapy
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Alabama at Birmingham
Laparoscopy, Discharge Planning
Post-discharge Monitoring Initiative on Outcomes of Post-surgical Patients
The investigators are conducting a prospective study to evaluate the SKH@Home programme, a post-discharge monitoring initiative for surgical patients.
- Trial name
- SKH@home (NCT06980402)
- Testing
- Early post-surgical discharge with post-surgical home based monitoring, Standard inpatient care until deemed suitable for discharge
- Volunteers
- 1,000 people
- Sponsor
- Sengkang General Hospital
Perianal Abscess, Anal Fistulas
Multicenter Study for Diagnosis and Treatment of Perianal Abscesses
Drainage of perianal abscesses is a well established treatment. Traditionally its been done in general anesthesia after the swelling has been localised its been drained with a knife.
- Conditions
- Perianal Abscess, Anal Fistulas, Incontinence
- Trial name
- NCT02306382
- Testing
- Perianal abscess drainage, 3D ultrasonography
- Where
- Sweden
- Volunteers
- 200 people
- Sponsor
- University Hospital, Umeå
Complicated Appendicitis, Intra-Abdominal Abscess
Laparoscopic Antibiotic Lavage to Prevent Intra-abdominal Abscess Formation in Complicated Appendicitis
Appendicitis is one of the most common causes of acute surgical admission. Presently, two types of appendicitis are distinguished: complicated and uncomplicated (phlegmonous).
- Trial name
- ALPACA (NCT06841003)
- Testing
- Laparoscopic antibiotic peritoneal lavage with gentamicin / clindamycin
- Where
- 11 sites in Netherlands
- Volunteers
- 752 people
- Sponsor
- Spaarne Gasthuis
Lung Adenocarcinoma, Lung Abscess
Evaluation of Different Sizes of Left-Sided Double-Lumen Tubes for Thoracic Surgery in a Tertiary Level Teaching Hospital
Double lumen tubes (DLT) have become standard of care for one lung ventilation in thoracic and esophageal surgeries. Selection of accurate size of DLT is important to achieve proper one lung ventilation, prevent trauma to airway…
- Trial name
- NCT07373171
- Testing
- Intubation of patients undergoing thoracic surgery with left sided double lumen tube
- Where
- Nepal
- Volunteers
- 60 people
- Sponsor
- Tribhuvan University, Nepal
Perianal Crohn Disease, Perianal Fistula
The Impact of Perianal Disease on Patient's Sex Life
Perianal diseases, such as perianal abcesses, anal fistulae and perianal Crohn's disease, are often associated with significant physical symptoms, including pain and chronic drainage.
- Conditions
- Perianal Crohn Disease, Perianal Fistula, Fistula in Ano, Perianal Abscess
- Trial name
- SEXTON (NCT07519850)
- Testing
- Patient Reported Outcome Assessment (Questionnaires)
- Where
- Greece
- Volunteers
- 60 people
- Sponsor
- AHEPA University Hospital
Pilonidal Sinus Disorder, Pilonidal Cyst Without Abscess
SiLaC Laser Technique for Pilonidal Sinus - La Paz Cohort Study.
Pilonidal sinus disease (PSD) is a chronic inflammatory condition of the sacrococcygeal region that frequently affects young adults, often causing pain, drainage, and recurrent infection.
- Conditions
- Pilonidal Sinus Disorder, Pilonidal Cyst Without Abscess, Pilonidal Sinus, Pilonidal Cysts
- Trial name
- SiLaC-LaPaz (NCT07260643)
- Testing
- SilaC
- Volunteers
- 40 people
- Sponsor
- Hospital Universitario La Paz
Brain Abscess, Fatigue
Cognitive Function and Fatigue After Brain Abscess
Brain abscess is a focal bacterial or fungal infection of the brain. Treatment is neurosurgical drainage of pus followed by long-term antibiotic treatment.
- Conditions
- Brain Abscess, Fatigue, Cognitive Dysfunction
- Trial name
- NCT04938362
- Testing
- FDG-PET, EEG
- Where
- Norway
- Volunteers
- 50 people
- Sponsor
- University of Oslo
Pilonidal Cyst Without Abscess
Laser Coagulation of Pilonidal Sinus With/Without Intraoperative Ultrasound Control
LASER COAGULATION OF THE PILONIDAL SINUS WITH INTRAOPERATIVE US CONTROL: PROTOCOL FOR A PROSPECTIVE MULTICENTER RANDOMIZED CLINICAL STUDY.
- Trial name
- LCPSwUsC (NCT07829315)
- Testing
- LASER COAGULATION OF THE PILONIDAL SINUS, LASER COAGULATION OF THE PILONIDAL SINUS WITH ULTRASONIC CONTROL
- Volunteers
- 310 people
- Sponsor
- State Scientific Centre of Coloproctology, Russian Federation
Oral Infection
Prediction Model for Delayed Extubation of Tracheal Intubation in Patients With Maxillofacial Space Infection After Abscess Incision and Drainage Surgery
Retrospective exploration of the risk factors associated with mechanical ventilation and tracheal extubation twenty-four hours after abscess incision and drainage surgery in patients with maxillofacial space infection.
- Trial name
- Prediction mod (NCT06853808)
- Volunteers
- 400 people
- Sponsor
- Henan Provincial People's Hospital
Appendicitis, Appendectomy
Re-assessment of Appendicitis Evaluation During Laparoscopic Appendectomy, Peritoneal Irrigation During Laparoscopic Appendectomy Does the Grade of Contamination Matter?
Type: prospective observational multicenter trial. Population of interest: adult patients undergoing laparoscopic appendectomy for acute appendicitis.
- Trial name
- RESIDENT1 (NCT05075252)
- Testing
- laparoscopic lavage
- Where
- Italy
- Volunteers
- 1,067 people
- Sponsor
- Niguarda Hospital
Periapical Periodontitis, Periapical Abscess
A Retrospective Cohort Study on the Non-Surgical Treatment of Periapical Inflammatory Lesions With Vitapex Paste
Background: Periapical inflammation is a common clinical condition, classified into periapical periodontitis, periapical granuloma, and periapical cyst.
- Conditions
- Periapical Periodontitis, Periapical Abscess, Periapical Radiolucency
- Trial name
- NCT07907367
- Testing
- Vitapex Paste
- Where
- China
- Volunteers
- 80 people
- Sponsor
- The Affiliated Hospital of Jinggangshan University
Breast Abscess
A Phase 2 Study of Methylene Blue Photodynamic Therapy for Treatment of Breast Abscesses
The objective of this Phase 2 study is to evaluate the efficacy of methylene blue photodynamic therapy (MB-PDT) performed at the time of percutaneous breast abscess drainage for disinfection of breast abscesses.
- Trial name
- NCT07179003
- Testing
- Standard of care breast abscess drainage, Methylene Blue, Lipid Emulsion
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Rochester
Liver Abscess, Amoebic Liver Abscess
Efficacy of Diloxanide Furoate as Additional Luminal Agent Along With Metronidazole for the Treatment of Amoebic Liver Abscess
Liver abscess is a common cause of presentation to medical emergency. Among the various causes of liver abscess, Amoebic liver abscess (ALA) is a frequent cause that can resemble pyogenic infections in tropical regions.
- Trial name
- DFALA RCT (NCT07807150)
- Testing
- Diloxanide furoate
- Where
- India
- Volunteers
- 220 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Intracranial Abscess
Transcranial Sonographic Evaluation of Preterm Neonates Presenting With Seizures and Its Association With IA
This study aimed to evaluate preterm neonates presenting with seizures using transcranial sonography (cranial ultrasound) to detect intracranial abnormalities.
- Trial name
- NCT07051382
- Testing
- Transcranial Sonographic Examination (Cranial Ultrasound)
- Where
- Pakistan
- Volunteers
- 122 people
- Sponsor
- Superior University
Perianal Abscess
Effect of Red and Blue Light Irradiation on Postoperative Wound Healing in Perianal Absces
This study aims to investigate whether specialized red-blue light irradiation facilitates faster postoperative recovery and reduces complication rates in patients following perianal abscess surgery.
- Trial name
- NCT07155356
- Testing
- Red light exposure, Red-blue light exposure
- Where
- China
- Volunteers
- 222 people
- Sponsor
- The Affiliated Hospital of Putian University
Perforated Appendicitis
APPI-Cost Trial for Perforated Appendicitis
The purpose of this study to assess the clinical effectiveness and cost-effectiveness of povidone-iodine (PVI) irrigation in perforated appendicitis, to investigate barriers and facilitators to future implementation of PVI…
- Trial name
- NCT06705842
- Testing
- PVI, Usual Care
- Where
- United States
- Volunteers
- 346 people
- Sponsor
- The University of Texas Health Science Center, Houston