Clinical trials: Able Bodied
Individuals With Functional Limitations Which May Impact Their Forward Reach
Normative Biomechanical Measures of Reaching in Able-Bodied Adults
A study to obtain normative values and repeatability measures during functional reaching tasks in able-bodied individuals with no functional limitations.
- Trial name
- NCT05328947
- Testing
- Modified Functional Reach and Functional Reach
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Stroke, Spinal Cord Injury
Synergistic Effect of Non-invasive Brain and Spinal Cord Stimulation
The goal of this clinical study is to investigate the potential synergy between non-invasive brain and spinal cord stimulation administered during a cognitive-motor task, in terms of their immediate effects on sensorimotor and…
- Conditions
- Stroke, Spinal Cord Injury, Able Bodied
- Trial name
- BrainSpineStim (NCT07334977)
- Testing
- tDCS, tSCS, Cognitive-Motor Task
- Where
- 2 sites in France
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Centre National de la Recherche Scientifique, France
Spinal Cord Injuries
VO2peak and Exercise Efficiency in Upper-body Poling
This study compares peak oxygen uptake (VO2peak) and exercise efficiency in upper-body poling versus arm crank ergometry in trained able-bodied and paraplegic participants.
- Trial name
- NCT03284086
- Testing
- upper-body double-poling, arm crank ergometry
- Where
- Norway
- Volunteers
- 18 people
- Sponsor
- Norwegian University of Science and Technology
Confidence Using a Wheelchair
Efficacy of Wheelchair Skills Training on Confidence Using a Manual Wheelchair
Background and Rationale: Mobility impairment is one of the main correlates of decreased levels of participation in daily and social activities.
- Trial name
- NCT01243164
- Testing
- Wheelchair Skills Training Program
- Where
- 2 sites in Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Healthy, Spastic Hemiparesis
Soleus Loading Response During Walking
Stroke survivors experience motor deficits, weak voluntary muscle activations, and low weight-bearing capacity that impair ambulation.
- Conditions
- Healthy, Spastic Hemiparesis, Stroke
- Trial name
- NCT05436366
- Testing
- Soleus loading response in able-bodied participants, Soleus loading response in participants with hemiparesis
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Victor H. Duenas
Lower Limb Amputation Above Knee (Injury)
Decoding Motion Planning Using Cortical Potentials
The team will investigate the user's intention to move by using cortical activity during a sit to stand movement performance in people with a transfemoral amputation and able-bodied individuals.
- Trial name
- NCT04325516
- Testing
- Daily activities
- Where
- Belgium
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Vrije Universiteit Brussel
Incomplete Spinal Cord Injury
The Effect of Acute Intermittent Hypoxia on Motor Learning
The goal of this study is to examine the effect of repetitive acute intermittent hypoxia on motor learning abilities in able-bodied individuals for subsequent study in individuals with incomplete spinal cord injury.
- Trial name
- NCT05341466
- Testing
- Acute Intermittent Hypoxia
- Where
- 2 sites in United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Boulder
Motor Disorders, Healthy
Non-invasive BCI-controlled Assistive Devices
Injuries affecting the central nervous system may disrupt the cortical pathways to muscles causing loss of motor control. Nevertheless, the brain still exhibits sensorimotor rhythms (SMRs) during movement intents or motor imagery…
- Conditions
- Motor Disorders, Healthy, Spinal Cord Injuries, Muscular Diseases
- Trial name
- NCT05183152
- Testing
- NMES Feedback, Visual Feedback, TESS
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Amputation; Traumatic, Arm, Upper
Teleoperation Experimental Comparison With Able-bodied Subjects
To compare the use of the semi-autonomous control algorithm (condition 1) with the standard of care myoelectric system used with the TASKA prosthetic hand (condition 2).
- Trial name
- NCT05048394
- Testing
- Semi-autonomous myoelectric control algorithm, Standard-of-care myoelectric control algorithm
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Point Designs
Spinal Cord Injuries, Constipation
Trancutaneous Abdominal Stimulation on Bowel Function.
This is a prospective, single-center, feasibility study to determine the sensations elicited by non-invasive abdominal electrical stimulation and its effects on bowel function in spinal cord injured individuals and in able-bodied…
- Trial name
- NCT04627168
- Testing
- Non-invasive, surface electrical stimulation device, DS5 Digitimer
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Amol Soin, M.D., MBA
Gait
AB Gait Estim Neurophysiology
This study is being done to answer the question: What are the effects of electrical stimulation and stepping practice on connections between the brain and muscles? The long-term goal of this project is to develop novel…
- Trial name
- NCT06430164
- Testing
- Gait Training, Functional electrical stimulation (FES), Peripheral electrical stimulation paired with cortical magnetic stimulation pulses
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Emory University
Caffeine, Spinal Cord Injury
Influence of Caffeine on HRV and Exercise Performance in Spinal Cord Injury
The aim is to investigate the influence of caffeine on heart rate variability and on performance in a 3 min exercise test in different population groups (able-bodied, paraplegic and tetraplegic subjects).
- Trial name
- NCT02083328
- Testing
- Caffeine
- Where
- Switzerland
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Swiss Paraplegic Research, Nottwil
Gastro Esophageal Reflux Disorder
GERD and Anti-Reflux Therapy Between Able-bodied and SCI Individuals
Respiratory dysfunction, esophageal dysmotility, and a gastroesophageal reflux disease (GERD) have been demonstrated to be highly prevalent in persons with SCI.
- Trial name
- NCT02584751
- Testing
- Omeprazole, 24 Hour pH Monitor, Pulmonary Function Examination
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- James J. Peters Veterans Affairs Medical Center
INCOMPLETE SPINAL CORD INJURY (ASIA D), Able Bodied
Examining the Effect of Acute Intermittent Hypoxia on Serum Blood Proteins and Lower Limb Function
The goal of this study is to clarify mechanisms of acute intermittent hypoxia and to examine the effect on lower limb function in persons with chronic, incomplete spinal cord injury.
- Trial name
- NCT06906536
- Testing
- Acute Intermittent Hypoxia (AIH)
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Boulder
Sleep Disordered Breathing, Able Bodied
Central Apnea in Heart Failure: Physiological Mechanisms to Inform Treatment
Central sleep apnea (CSA) is common in patients with heart failure and those using opioid analgesics. Unfortunately, effective treatment of central apnea remains elusive, pressure therapy given the modest efficiency of positive…
- Trial name
- CSA-HF (NCT07210606)
- Testing
- Trazodone + positive airway pressure (PAP) therapy, Oxygen + positive airway pressure (PAP) therapy
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Sleep Disordered Breathing, Able Bodied
Central Sleep Apnea : Physiologic Mechanisms to Inform Treatment
Central sleep apnea (CSA) is common in patients with heart failure and those using opioid analgesics. Unfortunately, effective treatment of central apnea remains elusive, pressure therapy given the modest efficiency of positive…
- Trial name
- CSA (NCT04118387)
- Testing
- Acetazolamide + supplemental oxygen + PAP therapy, Zolpidem + PAP therapy, Buspirone + PAP therapy
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Spinal Cord Injury, Able Bodied
Effects of a Virtual Reality-based Brain-Machine Interface Protocol in Spinal Cord Injury
Spinal cord injury (SCI) is a highly debilitating pathology, associated with the loss of sensorimotor functions, autonomy and quality of life.
- Conditions
- Spinal Cord Injury, Able Bodied, Traumatic Spinal Cord Injuries, Paraplegia, Spinal
- Trial name
- NCT07732868
- Testing
- Brain-Machine Interface
- Where
- 2 sites in Portugal
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- José Gabriel da Silva Figueiredo
Autonomic Dysfunction, Autonomic Imbalance
Non-Invasive Bioelectronic Analytics
Biomarkers can be evaluated to provide information about disease presence or intensity and treatment efficacy. By recording these biomarkers through noninvasive clinical techniques, it is possible to gain information about the…
- Conditions
- Autonomic Dysfunction, Autonomic Imbalance, Autonomic Nervous System Diseases, Vagus Nerve Autonomic Disorder
- Trial name
- NIBA (NCT04100486)
- Testing
- Standing-Squatting-Standing Test, Deep Breathing Test, Cold Pressor Test
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Stroke, Able Bodied
Stimulation-Based Modulation of Spinal and Cortical Sensory Pathways
The goal of this study is to assess cervical (neck) reflexes by intra-operatively stimulating the neck nerve roots to evoke motor responses through their connections to spinal motoneurons.
- Trial name
- NCT07401186
- Testing
- Bipolar Neural Stimulation Electrode
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Peter C. Gerszten, MD