Clinical trials: Abdominal Surgery, open to volunteers
Acute Kidney Injury
Intraabdominal Pressure Monitoring Urinary Catheter and Kidney Perfusion Pressure
The goal of this clinical trial is to determine whether monitoring intra-abdominal pressure (IAP) and adjusting blood pressure accordingly to maintain optimal renal perfusion pressure can reduce the risk of acute kidney injury…
- Trial name
- NCT06989762
- Testing
- Conventional Foley Catheter(Medline), Accuryn Foley Catheter
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Dang Tan Phat
Ventral Hernia
Bariatric SUrgery With Mesh REpair of Ventral Hernia: a Randomized Controlled Trial
The primary objective of the study is to demonstrate that hernia recurrence (VH) repair with non absorbable mesh concomitant to Bariatric Surgery (BS) decreases the risk of VH, with or without surgical repair, during the first…
- Trial name
- BeSURE (NCT05488288)
- Testing
- Mesh repair, Suture repair
- Where
- France
- Volunteers
- 354 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Surgical Stress Response, Inflammation
CoreSys Monitoring for Intraoperative Stress Management in Abdominal Hysterectomy
This randomized controlled trial evaluates whether intraoperative guidance using the CoreSys monitor reduces the surgical stress response in patients undergoing elective open abdominal hysterectomy.
- Conditions
- Surgical Stress Response, Inflammation, Anesthesia, Perioperative Care
- Trial name
- CORESTRESS (NCT07571473)
- Testing
- propofol, CoreSys Monitor, Remifentanil (Target-Controlled Infusion)
- Where
- Argentina
- Volunteers
- 30 people
- Sponsor
- Hospital Provincial de Rosario
Perioperative Care, Hemodynamics
ImPortance of Arterial Measurement Sites (IPAMS) on Intraoperative Hemodynamic Management
The goal of this clinical trial is to demonstrate the importance of arterial pressure measurement sites during major abdominal surgeries.
- Conditions
- Perioperative Care, Hemodynamics, Monitoring Blood Pressure, Arterial Lines
- Trial name
- IPAMS (NCT06982001)
- Testing
- Brachial line guided hemodynamic management, Radial line guided hemodynamic management, Radial line catheterization
- Where
- Canada
- Volunteers
- 204 people
- Sponsor
- Ciusss de L'Est de l'Île de Montréal
Inguinal Hernia Unilateral, Postoperative Pain Management
Transversalis Fascia Plane Block Versus Surgical Wound Infiltration for Postoperative Analgesia in Open Inguinal Hernia Repair
The purpose of this clinical trial is to evaluate whether two different analgesic techniques - ultrasound-guided Transversalis Fascia Plane Block (TFPB) and surgical wound infiltration - can improve postoperative pain control in…
- Conditions
- Inguinal Hernia Unilateral, Postoperative Pain Management, Regional Anaesthesia, Transversalis Fascia Plane Block
- Trial name
- TFPB-WIN (NCT07238829)
- Testing
- Ultrasound-Guided Transversalis Fascia Plane Block (TFPB), Surgical Wound Infiltration
- Volunteers
- 104 people
- Sponsor
- Ondokuz Mayıs University
Caudal Epidural Anesthesia, Erector Spinae Plane Block
Comparison of Erector Spinae Plane Block and Caudal Block in Pediatric Patients Aged 1 to 8 Years Undergoing Lower Abdominal Surgery
In routine pediatric surgical practice, lower abdominal surgeries are commonly performed. Inadequate control of postoperative pain can hinder functional recovery and may lead to negative behavioral changes as well as parental…
- Conditions
- Caudal Epidural Anesthesia, Erector Spinae Plane Block, Pediatric
- Trial name
- NCT07426939
- Testing
- caudal block, Erector Spinae Plane Block
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Postoperative Delirium (POD), Abdominal Neoplasms
Perioperative Biomarkers and Postoperative Delirium in Older Adults Undergoing Abdominal Cancer Surgery
This prospective observational cohort study aims to investigate the relationship between perioperative endogenous melatonin levels and postoperative delirium in patients aged 65 years or older undergoing elective abdominal cancer…
- Trial name
- NCT07859488
- Testing
- Perioperative Biomarker Assessment, Confusion Assessment Method (CAM)
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Fatma Cigdem Ozakin
Patients Undergoing Laparoscopic Inguinal Hernia Repair
The Effect of Cold Vapor on Dyspnea, Thirst, Nausea, and Physiological Parameters in the PACU After Laparoscopic Inguinal Hernia Surgery
Cold vapor application is considered a promising intervention with the potential to alleviate side effects associated with anesthesia and surgery in the postoperative period.
- Trial name
- NCT07273162
- Testing
- Cold Vapor
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- TC Erciyes University
Open Abdominal Surgery
EOIFP Block Versus OSTAP Block for Upper Abdominal Surgery
The investigators propose a single-center, assessor blinded, randomized control trial to compare the efficacy of external oblique fascial plane (EOIFP) block versus Oblique Subcostal Transversus Abdominis Plane (OSTAP) block for…
- Trial name
- NCT06409156
- Testing
- Oblique Subcostal Transversus Abdominis Plane Block, External Oblique Intercostal Fascial Plane block
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- The Cleveland Clinic
Intra Abdominal Pressure, Abdominal Compartment Syndrome
Intra-abdominal Hypertension and Abdominal Compartment Syndrome in Patients After Pancreatic Procedures.
This study investigates the development of intra-abdominal hypertension and compartment syndrome in patients undergoing elective pancreatic procedures.
- Conditions
- Intra Abdominal Pressure, Abdominal Compartment Syndrome, Pancreatic Surgery, Pancreatic Fistula After Pancreaticoduodenectomy
- Trial name
- HYPA (NCT06672601)
- Where
- Czechia
- Volunteers
- 150 people
- Sponsor
- Charles University, Czech Republic
Renal Perfusion, Minimally Invasive Surgical Procedures
Assessment of Renal Perfusion Using Ultrasound and Near-Infrared Spectroscopy in Patients Undergoing Minimally Invasive Abdominal Surgery
This prospective observational study aims to evaluate renal perfusion in adult patients undergoing elective minimally invasive abdominal surgery.
- Conditions
- Renal Perfusion, Minimally Invasive Surgical Procedures, Acute Kidney Injury
- Trial name
- RRI-NIRS (NCT07635160)
- Where
- Turkey (Türkiye)
- Volunteers
- 51 people
- Sponsor
- Istanbul University - Cerrahpasa
Cutaneous Sensory Blockade
Effects of Injection Volume and Site on Sensory Distribution After Rectus Sheath Block
This randomized controlled study aims to evaluate the effects of local anesthetic injection volume and injection site on cutaneous sensory distribution following ultrasound-guided rectus sheath block (RSB).
- Trial name
- RSB-SENSE (NCT07876297)
- Testing
- Ultrasound-Guided Upper Rectus Sheath Block (20 mL), Ultrasound-Guided Upper Rectus Sheath Block (30 mL), Ultrasound-Guided Middle Rectus Sheath Block (20 mL)
- Where
- Thailand
- Volunteers
- 120 people
- Sponsor
- Chiang Mai University
Hernia, Umbilical, Clonidine
Clonidine in Ultrasound-guided Rectus Sheath Block for Outpatient Umbilical Hernioplasty
This clinical trial aims to evaluate the effectiveness of an ultrasound-guided nerve block technique as the sole anesthetic method for patients undergoing outpatient umbilical hernia surgery.
- Conditions
- Hernia, Umbilical, Clonidine, Pain, Postoperative, Ambulatory Surgical Procedures
- Trial name
- NCT07062497
- Testing
- Rectus Sheath Block, Rectus Sheath Block with Clonidine
- Where
- Brazil
- Volunteers
- 62 people
- Sponsor
- Universidade Federal do Rio de Janeiro
Paralytic Ileus
Effect of Preoperative Intrathecal Dexamethasone Versus Dexmedetomidine on Paralytic Ileus After Major Abdominal Surgery
Postoperative Ileus (POI) is considered as intolerance of oral intake due to disruption of the normal coordinated propulsive motor activity of the gastrointestinal (GI) tract following abdominal or non-abdominal surgery.
- Trial name
- NCT06752317
- Testing
- Dexamethasone, Dexmedetomidine
- Volunteers
- 60 people
- Sponsor
- Assiut University
Prehabilitation, Major Abdominal Surgeries
PROPOSAL FOR A PREOPERATIVE FUNCTIONAL OPTIMIZATION PATHWAY FOR PATIENTS CANDIDATE FOR MAJOR SURGERY (CARDIAC AND ABDOMINAL ONCOLOGY)
The study aims to evaluate a prehabilitation protocol for patients undergoing cardiac and abdominal surgery. The project for a preparation program for cardiac surgery was developed within the framework of ERAS (Enhanced Recovery…
- Conditions
- Prehabilitation, Major Abdominal Surgeries, Cardiac Surgery, Multimodal and Integrated Program
- Trial name
- PRIME CARE (NCT07851350)
- Where
- 2 sites in Italy
- Volunteers
- 50 people
- Sponsor
- ASST Sette Laghi
Postoperative Pain
Rectus Abdominis Muscle Parameters and Postoperative Opioid Consumption in Geriatric Patients
This prospective observational study aims to evaluate the relationship between ultrasound-derived rectus abdominis muscle thickness and thickening fraction and postoperative opioid consumption in geriatric patients undergoing…
- Trial name
- NCT07545824
- Testing
- Ultrasound-Guided Rectus Sheath Block
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people
- Sponsor
- Istinye University
Laparoscopy, Discharge Planning
Post-discharge Monitoring Initiative on Outcomes of Post-surgical Patients
The investigators are conducting a prospective study to evaluate the SKH@Home programme, a post-discharge monitoring initiative for surgical patients.
- Trial name
- SKH@home (NCT06980402)
- Testing
- Early post-surgical discharge with post-surgical home based monitoring, Standard inpatient care until deemed suitable for discharge
- Volunteers
- 1,000 people
- Sponsor
- Sengkang General Hospital
Abdominal Surgery
Mobilisation and Breathing Exercises After Abdominal Surgery at Sahlgrenska University Hospital
The aim of the study is to evaluate the effect of a new care strategy, including earlier and more intensive mobilization and individually adapted breathing exercises, regarding length of stay, recovery, complications and which…
- Trial name
- SUMO (NCT06809036)
- Where
- Sweden
- Volunteers
- 100 people
- Sponsor
- Göteborg University
Intraoperative Hypotension, Postoperative Pulmonary Complications (PPCs)
PRO STRESS Trial: Proactive Low-Dose Norepinephrine to Reduce Intraoperative Fluid Administration in Patients at High-Risk for Postoperative Pulmonary Complications Undergoing Laparoscopic Abdominal Surgery
Intraoperative hypotension is commonly treated with fluid administration; however, excessive fluid therapy may contribute to postoperative pulmonary complications.
- Conditions
- Intraoperative Hypotension, Postoperative Pulmonary Complications (PPCs), Fluid Over-load
- Trial name
- PRO STRESS (NCT07627360)
- Testing
- Norepinephrine
- Where
- Egypt
- Volunteers
- 130 people
- Sponsor
- Suez Canal University
Retrolaminar Block, TAP Block
Ultrasound Guided Retrolaminar Block Versus Transverse Abdominis Plane Block in Laparoscopic Upper Abdominal Surgeries
This study aims to compare and evaluate the safety and efficacy of ultrasound guided retrolaminar block versus transverse abdominis plane block in laparoscopic upper abdominal surgeries.
- Conditions
- Retrolaminar Block, TAP Block, Laparoscopic Abdominal Surgeries
- Trial name
- NCT07720817
- Testing
- Ultrasound-guided Retrolaminar Block group, Transverses Abdominis Plane (TAP) Block Group
- Where
- Egypt
- Volunteers
- 164 people
- Sponsor
- Mansoura University