Clinical trials: Abdominal Obesity, open to volunteers
Obese Patients, Hypothalamic Neoplasms
KETO-TUMOR: a Study on Brain Tumors and Central Obesity
Hypothalamic-chiasmatic tumours account for 5-10% of CNS tumours in children and can compromise hypothalamic function, causing alterations in energy balance and weight gain.
- Trial name
- NCT07396896
- Testing
- Dietary intervention
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- Meyer Children's Hospital IRCCS
Metabolic Syndrome, Insulin Resistance
Asprosin and miRNA Expression in Young Women With Metabolic Syndrome
Metabolic syndrome is a major risk factor for cardiovascular disease and type 2 diabetes, and its prevalence in young adults is increasing. Early identification of individuals at risk may improve prevention strategies.
- Conditions
- Metabolic Syndrome, Insulin Resistance, Obesity, Abdominal, Dyslipidemias
- Trial name
- ASPRO-MetS (NCT07917364)
- Testing
- Biomarker panel (asprosin, microRNA, BDNF, cortisol), Clinical and questionnaire assessment
- Where
- Poland
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- University of Applied Sciences in Nowy Targ
Overweight, Prediabetic State
A Study of Orforglipron in Participants With Overweight at Risk of Development of Obesity-Related Complications or Progression to Class 1 Obesity
This study will evaluate the efficacy and safety of orforglipron in participants with overweight and assess whether it helps reduce the future risk of obesity-related conditions, including type 2 diabetes, hypertension, and…
- Conditions
- Overweight, Prediabetic State, Prehypertension, Obesity, Abdominal
- Trial name
- ATTAIN-NOW (NCT07794579)
- Testing
- Orforglipron
- Where
- 180 sites in United States, Argentina and 10 more
- Volunteers
- 2,001 people
- Sponsor
- Eli Lilly and Company
Resistant Hypertension, Hemodynamic Instability
Effect of Electrical Stimulation and Exercise on Blood Flow in Patients With Resistant High Blood Pressure
The goal of this clinical trial is to learn if the combination between transcutaneous electrical nerve stimulation (TENS) and isometric exercise (IE) can improve blood pressure in men and women between 50 to 60 years old suffered…
- Conditions
- Resistant Hypertension, Hemodynamic Instability, Essential (Primary) Hypertension, Abdominal Obesity
- Trial name
- NCT07383220
- Testing
- Transcutaneous Electrical Nerve Stimulation, Isometric Exercise, Aerobic, Dynamic Resistance, stretch and Breathing Exercises and Lifestyle Modification Advices
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Mohamed Mohamed Ali Morgan
Healthy, Brain Insulin Sensitivity
Long-Term Effects of Walnut Consumption on Brain Function
Rationale: Healthy foods, including mixed nuts, may improve brain function, which is essential for cognitive and metabolic health, and may contribute to improved food intake regulation.
- Conditions
- Healthy, Brain Insulin Sensitivity, Cerebral Blood Flow, Brain Vascular Function
- Trial name
- WalBrain (NCT07422220)
- Testing
- Walnuts
- Where
- Netherlands
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Metabolic Syndrom
Response Of Metabolic Syndrome Severity Score To High Intenisty Interval Training In Women With Central Obesity.
This study will be conducted to investigate any significant effect of high intensity interval training on metabolic syndrome severity score in women with central obesity.
- Trial name
- NCT06509464
- Testing
- High intensity interval training, Caloric restricted diet
- Where
- Egypt
- Volunteers
- 48 people
- Sponsor
- Soma Adel Gaber Abd El-Ghany
Obesity, Abdominal Obesity
Acupuncture for Prediabetes With Combined Obesity
The clinical trial aims to evaluate the efficacy and safety of acupuncture in reducing weight and waist circumference while modulating glucose and lipid metabolism in Prediabetes with Combined Obesity.
- Conditions
- Obesity, Abdominal Obesity, PreDiabetes
- Trial name
- NCT06359418
- Testing
- Acupuncture
- Where
- China
- Volunteers
- 260 people
- Sponsor
- Guang'anmen Hospital of China Academy of Chinese Medical Sciences
Abdominal Obesity
Evaluation of Exercise Capacity in Teenage Females Using Virtual Reality and Plyometric Workout
to evaluate the efficacy of virtual reality combined with plyometric workout on abdominal obesity in adolescent females
- Trial name
- VR (NCT07092228)
- Testing
- virtual reality and plyometric workout
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- New Ismailia National University
Obesity & Overweight, Older Women
Effects of Adapted Taekwondo Versus Conventional Training on Anthropometric Variables and Physical Function in Older Women With Abdominal Obesity
Therefore, this study aimed to analyze the effects of TKD on anthropometric and physical function parameters in older women with abdominal obesity, compared with conventional exercise interventions such as MCT, and WE.
- Trial name
- RCT (NCT07705750)
- Testing
- taekwondo training, multicomponent training, walking exercise
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Universidad Católica del Maule
Critical Illness, Obesity & Overweight
Body Roundness Index and Mortality in ICU Patients
This study investigates whether Body Roundness Index (BRI), an anthropometric measure derived from waist circumference and height, can predict mortality in adult intensive care unit (ICU) patients.
- Conditions
- Critical Illness, Obesity & Overweight, Mortality in Intensive Care Units, Body Composition
- Trial name
- BRI-ICU (NCT07631429)
- Where
- Turkey (Türkiye)
- Volunteers
- 550 people
- Sponsor
- Ondokuz Mayıs University
Obesity, Type 2 Diabetes Mellitus
Radiomics of Intra-abdominal and Subcutaneous Adipose Tissue Predict the Efficacy of Bariatric Surgery (RISABS)
Using radiomics of intra-abdominal and subcutaneous adipose tissue and clinical features to predict the weight loss efficacy and remission of type 2 diabetes mellitus after bariatric surgery.
- Conditions
- Obesity, Type 2 Diabetes Mellitus, Bariatric Surgery
- Trial name
- NCT06169033
- Where
- China
- Volunteers
- 800 people
- Sponsor
- China-Japan Friendship Hospital
Menopause, Obesity, Abdominal
Bioenergetic Effects of Aging and Menopause (BEAM)
The menopause transition is associated with increased risk for weight gain and a shift toward storing fat in the belly region, which may increase risk for cardiovascular disease and diabetes.
- Conditions
- Menopause, Obesity, Abdominal, Aging, Weight Gain
- Trial name
- BEAM (NCT04043520)
- Testing
- GnRH antagonist, Estrogen Product
- Where
- United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Diabetes Mellitus, Type 2, Obesity
Culturally Adapted Dietary Clinical Trial in PR
This project will determine whether a diet culturally adapted to adults in Puerto Rico can effectively decrease cardiometabolic risk factors.
- Conditions
- Diabetes Mellitus, Type 2, Obesity, Hypertension, Dyslipidemias
- Trial name
- PRECISION (NCT05962372)
- Testing
- Culturally tailored food and diet advice, Standard healthy eating advice
- Where
- Puerto Rico
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Harvard School of Public Health (HSPH)
Obesity, Obesity, Abdominal
Acupoint Catgut Embedding With Laser Acupuncture for Weight Loss in Adults With Obesity
Acupoint catgut embedding and laser acupuncture have each been studied as treatments for obesity in adults, but the two have not been evaluated in combination, and few trials have measured anthropometric, biochemical, and blood…
- Conditions
- Obesity, Obesity, Abdominal, Overweight
- Trial name
- NCT07770893
- Testing
- Acupoint catgut embedding, Active laser acupuncture, Dietary and exercise counseling
- Where
- Taiwan
- Volunteers
- 120 people
- Sponsor
- Taipei City Hospital
HIV-1-infection, Frailty
Tesamorelin as an Adjunct to Exercise for Improving Physical Function in HIV
People with HIV experience earlier impairments in physical function compared to people in the general population. They also exhibit an earlier presentation and more rapid development of frailty, a multisystemic syndrome of aging…
- Conditions
- HIV-1-infection, Frailty, Impaired Physical Function, Abdominal Obesity
- Trial name
- TRIUMPH (NCT06554717)
- Testing
- Tesamorelin, Exercise
- Where
- 2 sites in United States
- Volunteers
- 100 people
- Sponsor
- Massachusetts General Hospital
Menopause
Midlife Empowerment and Longevity Through Optimizing Wellness
The goal of this observational longitudinal study is to understand how lifestyle behaviours, menopausal symptoms, and digital health data change over time in women experiencing perimenopause or menopause, and to evaluate whether…
- Trial name
- MELOW (NCT07713862)
- Testing
- MELOW
- Volunteers
- 200 people
- Sponsor
- National University Health System, Singapore
Non Invasive Body Contouring
Clinical Evaluation of Linear Z for Body Contouring
This clinical study will evaluate the safety and effectiveness of LinearZ, a non-invasive focused ultrasound device, for body contouring of the lower abdomen and flanks.
- Trial name
- NCT07802431
- Testing
- High Intensity Focused Ultrasound
- Where
- Mexico
- Volunteers
- 30 people
- Sponsor
- Jeisys Medical Inc
Obesity, Obesity, Morbid
Endoscopic Metabolic and Bariatric Therapies
This is a prospective collection of data from adult patients who have had an endoscopic metabolic and bariatric endoscopy procedure (EMBT) for primary or revision surgical procedures for obesity.
- Conditions
- Obesity, Obesity, Morbid, Obesity Associated Disorder, Bariatric Surgery Candidate
- Trial name
- EMBTs (NCT05725967)
- Testing
- Primary Obesity Endoscopic Procedures, Endoscopic Revision of Bariatric Surgical Procedures, Bariatric Surgery Procedures
- Where
- United States
- Volunteers
- 5,000 people
- Sponsor
- Christopher C. Thompson, MD, MSc
Obesity, Chronic Pain
Chronic Abdominal Pain After Laparoscopic Sleeve Gastrectomy
The study aims to evaluate the prevalence of postoperative chronic pain, defined as the persistence of abdominal pain for more than 3 months after laparoscopic sleeve gastrectomy.
- Conditions
- Obesity, Chronic Pain, Abdominal Pain
- Trial name
- Chron Pain LSG (NCT06686875)
- Testing
- Questionnaire
- Where
- Poland
- Volunteers
- 200 people
- Sponsor
- Medical University of Warsaw
Obese Individuals, Central Adiposity
Post-exercise Blood Pressure With Inorganic Nitrate
This study is examining whether acute inorganic nitrate supplementation in the form of beetroot juice, paired with an acute bout of exercise, affects blood pressure and what is the magnitude of the difference compared to exercise…
- Trial name
- BEET-DOWN (NCT07869472)
- Testing
- Beetroot Juice - Active + Exercise, Beetroot Juice - Active + No exercise
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Virginia