Clinical trials: Abdominal Hysterectomy, open to volunteers
Surgical Stress Response, Inflammation
CoreSys Monitoring for Intraoperative Stress Management in Abdominal Hysterectomy
This randomized controlled trial evaluates whether intraoperative guidance using the CoreSys monitor reduces the surgical stress response in patients undergoing elective open abdominal hysterectomy.
- Conditions
- Surgical Stress Response, Inflammation, Anesthesia, Perioperative Care
- Trial name
- CORESTRESS (NCT07571473)
- Testing
- propofol, CoreSys Monitor, Remifentanil (Target-Controlled Infusion)
- Where
- Argentina
- Volunteers
- 30 people
- Sponsor
- Hospital Provincial de Rosario
Cervical Cancer
German-funded Laparoscopic Approach to Cervical Cancer
The G-LACC trial is a prospective, interventional, multicenter, open-label, randomized and controlled non-inferiority operative trial.
- Trial name
- G-LACC (NCT06489795)
- Testing
- Laparoscopic or robot-assisted radical/simple hysterectomy, Abdominal radical/simple hysterectomy
- Where
- 14 sites in Germany
- Volunteers
- 756 people
- Sponsor
- Hannover Medical School
Erector Spinae Block, Enhanced Recovery After Surgery (ERAS) Protocol
Erector Spinae Block in Reducing Peri-operative Opioid Consumption in Total Abdominal Hystrectomy
Hystrectomy is a surgical procedure that involves removal of uterus from the body of patient using a lower abdominal incision. This is an extremely painful procedure which causes discomfort and greatly increases opioids…
- Conditions
- Erector Spinae Block, Enhanced Recovery After Surgery (ERAS) Protocol, Opioid
- Trial name
- NCT07178262
- Testing
- Erector Spinae (ESP) Block with Bupivacaine (Marcaine®)
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Kulsoom International Hospital
Abdomen Cancer, Pancreas Adenocarcinoma (MSI-H)
Implementation of a Pain Management Plan in Major Open Abdominal Surgeries.
Introduction: Major abdominal surgery encompasses a broad range of surgical procedures in heterogeneous patient populations.Management of postoperative pain has received keen attention in recent years with considerable concurrent…
- Conditions
- Abdomen Cancer, Pancreas Adenocarcinoma (MSI-H), Colectomy Left/Right/Total Under Laparotomy, Hepatectomy
- Trial name
- NCT07901582
- Testing
- Epidural administered opioid
- Where
- Greece
- Volunteers
- 58 people
- Sponsor
- National and Kapodistrian University of Athens
Abdominal Hysterectomy
COMPARISON of the EFFECT of TWO DIFFERENT ANALGESIS TECHNIQUES in ABDOMINAL HYSTERECTOMY
Hysterectomy is one of the most commonly performed surgical procedures after cesarean section in many countries worldwide, especially among women of reproductive age.
- Trial name
- NCT06815393
- Testing
- Intratechal Morphine, Transversalis Fascia Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Ataturk Training and Research Hospital
Myoma;Uterus, Adenomyosis of Uterus
RCT - Efficacy of Intravenous Vitamin C Versus Placebo on Estimated Blood Loss in Total Abdominal Hysterectomy
Intervention Group: Received two 1 gm doses of Vitamin C intravenously (IV). first Dose: At midnight on the day of surgery. Second Dose: Immediately after the surgical incision.
- Trial name
- Vit C in TAH (NCT07335432)
- Testing
- Vitamin C (Ascorbic Acid)
- Where
- Thailand
- Volunteers
- 40 people
- Sponsor
- Queen Savang Vadhana Memorial Hospital, Thailand
Hysterectomy
Comparative Study Between the Analgesic Effect of Dexmedetomidine and Magnesium Sulfate as Adjuvant to Bupivacaine Using Ultrasound-Guided Transversus Abdominis Plane Block in Abdominal Hysterectomy : A Randomized Double-blinded Study
Over 80% of patients who undergo surgery suffer from acute postoperative pain, with 75% of them rating the pain severity as moderate, severe, or extreme.
- Trial name
- NCT06720337
- Testing
- bupivacaine 0.5%, Dexmedetomidine, MgSO4
- Volunteers
- 64 people
- Sponsor
- Assiut University
Hysterectomy, Benign Uterine Diseases, Hysterectomy, Vaginal
Effect of Abdominal Ice Pack After vNOTES Hysterectomy
This randomized, controlled, open-label, parallel-group clinical trial is designed to investigate the efficacy of abdominal ice pack application as an adjunct to standard pain management following vNOTES (Vaginal Natural Orifice…
- Conditions
- Hysterectomy, Benign Uterine Diseases, Hysterectomy, Vaginal, vNOTES, Postoperative Pain Following Hysterectomy
- Trial name
- NCT07626684
- Testing
- Abdominal Ice Pack + ERAS
- Where
- Turkey (Türkiye)
- Volunteers
- 122 people
- Sponsor
- Erzincan Military Hospital
Post Operative Analgesia
Comparative Study Between Ultrasound Guided Paravertebral Plane Block and Erector Spinae Plane Block on Post-operative Analgesia After Total Abdominal Hysterectomy
The intent of this study is to compare the efficacy of the erector spinae plane block (ESPB) and paravertebral plane block in reducing postoperative opioid consumption and pain in patients with total abdominal hysterectomy.
- Trial name
- NCT07610070
- Testing
- Paravertebral Plane Block, Erector Spinea Plane Block, bupivicaine 0.25%
- Where
- Egypt
- Volunteers
- 48 people
- Sponsor
- Ain Shams University
Abdominal Hysterectomy
Effect of Intrathecal Magnesium Sulfate Versus Intravenous Magnesium Sulfate on Postoperative Pain After Abdominal Hysterectomy
The present study aims to compare the effect of adding IV magnesium sulfate versus magnesium sulfate to intrathecal hyperbaric bupivacaine in total abdominal hysterectomy regarding the duration of postoperative analgesia…
- Trial name
- NCT06367595
- Testing
- Magnesium sulfate
- Volunteers
- 90 people
- Sponsor
- Assiut University
Postoperative Pain, Total Abdominal Hysterectomy
Dexmedetomidine Versus Ketamine in TAP Block for Postoperative Analgesia After Total Abdominal Hysterectomy
Total abdominal hysterectomy is associated with significant postoperative pain due to abdominal wall incision and tissue manipulation.
- Trial name
- NCT07845643
- Testing
- TAP block using Dexmedetomidine & Bupivacaine, TAP block using Ketamine Hydrochloride and Bupivacaine
- Where
- Bangladesh
- Volunteers
- 64 people
- Sponsor
- Bangladesh Medical University
Cervical Cancer, Hysterectomy
Minimally Invasive Surgery Versus Open Radical Hysterectomy in Presumably Early Stage Cervical Cancer: a Retrospective Multicenter Non-inferiority Study Comparing Overall and Progression-free Survival.
The goal of this retrospective observational study with prospective follow-up is to compare the safety and treatment outcomes of radical laparoscopic hysterectomy (removal of the uterus with cervix) versus abdominal (open)…
- Trial name
- MOOSE (NCT07120529)
- Testing
- CT scan, Ultrasound scan (Transvaginal or Transabdominal), Gynecological examination
- Where
- 5 sites in Poland
- Volunteers
- 300 people
- Sponsor
- Medical University of Silesia
Pain Management, Hysterectomy
Comparison of Sensory Block Coverage and Clinical Effectiveness of TAP and Rectus Sheath Blocks in Pfannenstiel Incisions
Hysterectomy is one of the most common major gynecologic surgeries performed for various indications, and hundreds of thousands of procedures are carried out annually, particularly in developed countries.
- Trial name
- NCT07260396
- Testing
- Group Transversus Abdominis Plane Block, Group Rectus Sheath Block
- Volunteers
- 30 people
- Sponsor
- Samsun University
Abdominal Hysterectomy
The Effect of Two Different Analgesic Techniques on Postoperative Recovery Quality
Hysterectomy is one of the most frequently performed surgical procedures after Caesarean section in many countries of the world and involves the removal of the uterine corpus with or without the cervix (total hysterectomy) or…
- Trial name
- NCT06766994
- Testing
- intrathecal morphine, Erector Spinae Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Ataturk University
Cervical Cancer Stage IB2
Modified Tumor-free Techniques Operation to Cervical Cancer
The goal of this clinical trial is to learn if laparoscopic radical hysterectomy incorporating modified tumor-free techniques (LRH-MTF) works to treat FIGO stage IB2 cervical cancer as good as abdominal radical hysterectomy…
- Trial name
- MOTTO (NCT06836869)
- Testing
- Laparoscopic radical hysterectomy incorporating modified tumor-free techniques, Abdominal radical hysterectomy
- Where
- 17 sites in China
- Volunteers
- 524 people
- Sponsor
- Peking Union Medical College Hospital
Immune-Nutritional Indexes (PNI, HALP), Postoperative Sleep Quality
Immune-Nutritional Scores and Sleep Quality After Total Abdominal Hysterectomy
This prospective observational study aims to evaluate the relationship between preoperative immune-nutritional status and postoperative sleep quality in women undergoing total abdominal hysterectomy under general anesthesia.
- Trial name
- NCT07038564
- Testing
- Immune-Nutritional Scoring and Postoperative Sleep Assessment
- Volunteers
- 60 people
- Sponsor
- Istinye University
Benign Gynecologic Conditions
Comparison of the Outcomes of Total Laparoscopic Hysterectomy Versus Total Abdominal Hysterectomy for Benign Gynecologic Conditions in a Limited-resources Setting.
Minimally invasive hysterectomy (laparoscopic) is associated with shorter hospital stay, less blood loss, faster recovery, and improved early postoperative quality of life compared with open abdominal hysterectomy.
- Trial name
- NCT07496814
- Volunteers
- 32 people
- Sponsor
- Assiut University
Superior Hypogastric Plexus Block, Transversus Abdominis Plane Block
Combination of Superior Hypogastric Plexus Block and Transversus Abdominis Plane Block in Abdominal Hysterectomies
This study aims to evaluate the analgesic effect of superior hypogastric plexus block combined with transversus abdominis plane block in abdominal hysterectomies.
- Conditions
- Superior Hypogastric Plexus Block, Transversus Abdominis Plane Block, Abdominal Hysterectomies
- Trial name
- NCT07606781
- Testing
- Superior hypogastric plexus block + Transverse abdominis plane, Superior hypogastric plexus block
- Where
- Egypt
- Volunteers
- 44 people
- Sponsor
- Tanta University
Post Operative Analgesia
Erector Spinae Plane Versus Quadratus Lumborum Blocks for Pain Management After Total Abdominal Hysterectomy
TAH, being a large scale gynaecological operation, is a construction bound to cause serious postoperative pain to the patient in that the procedure will inevitably entail massive tissue dissection.
- Trial name
- NCT07480499
- Testing
- Erector Spinae Plane Block, Quadratus Lumborum Block (QLB)
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Sheikh Khalifa Bin Zayed Al Nahyan Combined Military Hospital Muzaffarabad
Leiomyoma (Uterine Fibroids), Adenomyoma of Uterus
The Effect of Uterine Manipulator Use During Abdominal Hysterectomy on Postoperative Sexual Function
This prospective, single-center, randomized controlled trial aims to evaluate the effect of uterine manipulator use during total abdominal hysterectomy on postoperative female sexual function at 3 months, assessed by the Female…
- Conditions
- Leiomyoma (Uterine Fibroids), Adenomyoma of Uterus, Uterine Bleeding
- Trial name
- UMAH (NCT07431788)
- Testing
- Uterine Manipulator, Conventional Abdominal Hysterectomy
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Erkan Gol