Clinical trials: ART
Infection, Human Immunodeficiency Virus
PENTA Fosamprenavir Study
Twice daily fosamprenavir, in combination with low dose ritonavir (FPV/RTV BID), is indicated for the treatment of HIV-infected adults, adolescents and children of 6 years of age and above for use in combination with other…
- Trial name
- NCT01077635
- Testing
- Exposure to licensed dose of FPV (+/- 20% of 18mg/kg BID + RTV)
- Volunteers
- 1 people
- Sponsor
- ViiV Healthcare
Acquired Immune Deficiency Syndrome Virus
Atorvastatin for HAART Suboptimal Responders
We hypothesise that atorvastatin changes immune activation among HAART-treated adults with suboptimal cluster cell differentiation 4 (CD4) recovery by 25%
- Trial name
- NCT01766076
- Testing
- atorvastatin, Lipitor®
- Volunteers
- 30 people
- Sponsor
- Makerere University
HIV
Comparing Food and Cash Assistance for HIV-Positive Men and Women on Antiretroviral Therapy in Tanzania
The importance of good nutrition and food security among people living with HIV infection (PLHIV) is widely recognized. In resource-constrained settings, food insecurity is increasingly recognized as an important barrier to…
- Trial name
- NCT01957917
- Testing
- NAC (Nutritional Assessment and Counseling), Cash Transfer, Food Assistance
- Where
- 4 sites in Tanzania
- Volunteers
- 800 people
- Sponsor
- University of California, Berkeley
Contraceptive Usage
A Prospective Observational Study of the Performance of Zarin in Kenya
This will be a non-comparative prospective observational study of women using Zarin as a primary method of contraception in Kenya.
- Trial name
- NCT01334190
- Where
- Kenya
- Volunteers
- 602 people, healthy volunteers welcome
- Sponsor
- FHI 360
Oncologic Disease, Chemotherapy
Comparing the Effects of Art Therapy and Mandala Application on State Anxiety Levels in Chemotherapy Patients
The research is planned as a randomized controlled trial with a two-group (art-based flow drawing and mandala), pre-test, post-test design.
- Trial name
- NCT07435597
- Testing
- Mandala therapy, Art therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Atlas University
Well Aging, Health Impairment
Effects of Montreal Museum of Fine Arts Visits and Older Community Dwellers With a Precarious State
This study evaluates the effects of MMFA visits on psychological, health, social conditions and personal interactions in older community dwellers with a precarious state and to determine whether these effects may change precarity.
- Conditions
- Well Aging, Health Impairment, Social Isolation, Old Age
- Trial name
- NCT03962985
- Testing
- Guided tour at the Montreal Museum of Fine Arts
- Where
- Canada
- Volunteers
- 41 people
- Sponsor
- Jewish General Hospital
HIV Infections
Effectiveness and Safety of Epivir/Ziagen/Zerit (3TC/ABC/d4T) Versus Epivir/Ziagen/Sustiva (3TC/ABC/EFV) Versus Epivir/Ziagen/Agenerase/Norvir (3TC/ABC/APV/RTV) in HIV Patients Who Have Never Received Treatment
The purpose of this study is to see how effective and safe it is to give 1 of the 3 following treatments to patients who may not have received anti-HIV treatment: 1) lamivudine (3TC)/abacavir (ABC)/stavudine (d4T); 2)…
- Trial name
- NCT00005017
- Testing
- Ritonavir, Abacavir sulfate, Amprenavir
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Glaxo Wellcome
Malaria
Efficacy and Safety of Amodiaquine and Amodiaquine-Artesunate
The purpose of this study is to compare the efficacy and safety of two antimalarial drug regimes, namely amodiaquine versus amodiaquine-artesunate, in the treatment of children with uncomplicated malaria.
- Trial name
- NCT00238017
- Testing
- amodiaquine-artesunate versus amodiaquine
- Where
- Ghana
- Volunteers
- 400 people
- Sponsor
- Charite University, Berlin, Germany
HIV Seropositivity
Clinical Trial of Gammora® Plus Antiretroviral Treatment for HIV
The goal of this phase II, open-label, randomized, controlled clinical trial is to evaluate the impact of Gammora®, a 16-mer HIV integrase-derived peptide associated with a boosted darunavir antiretroviral regimen compared…
- Trial name
- NCT06799650
- Testing
- Gammora®
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- Federal University of São Paulo
HIV, Contraception
Darunavir and Rilpivirine Interactions With Etonogestrel Contraceptive Implant
This study will evaluate the pharmacokinetic properties of rilpivirine and darunavir when used in combination with etonogestrel
- Trial name
- DRIVE-1 (NCT03589040)
- Testing
- Etonogestrel 68Mg Implant, rilpivirine, darunavir
- Where
- Uganda
- Volunteers
- 60 people
- Sponsor
- Makerere University
Pediatric Cancer Chemotherapy-Related Symptoms Anxiety
An AI-Assisted Art Therapy Co-Creation Intervention
This randomized controlled trial aims to evaluate the effects of an AI-assisted interactive art therapy co-creation intervention on symptom burden, state anxiety, and emotional regulation in pediatric patients receiving…
- Trial name
- NCT07362615
- Testing
- AI-based art-based program
- Volunteers
- 60 people
- Sponsor
- Gazi University
Human Immunodeficiency Virus Infections
Attitudes and Beliefs and the Steps of HIV Care
Through a prospective observational cohort study enrolling patients newly diagnosed with Human immunodeficiency virus (HIV): Aim 1: Assess attitudes and beliefs about HIV disease and care over time and relate those attitudes and…
- Trial name
- NCT00749840
- Testing
- Questionnaire
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- M.D. Anderson Cancer Center
Mental Disease, şizofreni
EXPRESSIVE ARTS THERAPY FOR HOPE IN PEOPLE WITH SCHIZOPHRENIA
This randomized controlled trial aimed to evaluate the effectiveness of an expressive arts therapy programme based on positive psychotherapy principles in strengthening hope among individuals diagnosed with schizophrenia.
- Trial name
- EAT-HOPE (NCT07453355)
- Testing
- Expressive Arts Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Ondokuz Mayıs University
Pregnancy Prevention
Continuous Use of COCs
The primary objective is to determine if continuous COC use leads to higher continuation rates over 12 months of follow up than use of the standard 28-day COC regimen.
- Trial name
- NCT00570440
- Testing
- Oral contraceptives--ethinyl estradiol, levonorgestrel
- Where
- 2 sites in Dominican Republic, Nicaragua
- Volunteers
- 362 people, healthy volunteers welcome
- Sponsor
- FHI 360
Acquired Immunodeficiency Syndrome
Dimiracetam in Painful Neuropathies Affecting AIDS Patients
The purpose of this study is to assess the efficacy and tolerability of orally administered dimiracetam for 10 weeks to AIDS patients under treatment with antiretroviral agents presenting a disease and /or treatment related…
- Trial name
- DIPANAP (NCT01444690)
- Testing
- Dimiracetam, Dimiracetam 25 mg
- Where
- Switzerland
- Volunteers
- 244 people
- Sponsor
- Neurotune AG
HIV Infection
Antiretroviral-Sparing Concept With HIV-specific T Cell Precursors With High Proliferative Capacity (PHPC)
PHPC-02 is a phase II, randomized, placebo-controlled trial designed to investigate whether therapeutic immunization during highly active antiretroviral therapy (HAART) induces elevations of HIV-specific T cell precursors with…
- Trial name
- PHPC-02 (NCT00918840)
- Testing
- DermaVir, HAART
- Where
- Italy
- Volunteers
- 16 people
- Sponsor
- Genetic Immunity
HIV Infections
Viral Load Triggered ART Care in Lesotho
This cluster randomized clinical trial at 18 nurse-led rural health centers in Lesotho will test an automated differentiated service delivery model using viral load results, other clinical characteristics and participants'…
- Trial name
- VITAL (NCT04527874)
- Testing
- VITAL model
- Where
- 18 sites in Lesotho
- Volunteers
- 5,809 people
- Sponsor
- Swiss Tropical & Public Health Institute
HIV Infections, ART
Accelerated ART Initiation for PWHIV Who Are Out of Care
The main purpose of the study is to evaluate the effectiveness, of the ACCELERATE model of care to achieve HIV viral suppression at Week 24.
- Conditions
- HIV Infections, ART, Noncompliance, Patient
- Trial name
- ACCELERATE (NCT06374758)
- Testing
- The Accelerate model of care, bictegravir/emtricitabine/tenofovir alafenamide 50/200/25 mg
- Where
- 4 sites in United States
- Volunteers
- 120 people
- Sponsor
- University of Missouri-Columbia
HIV Infection, Hepatitis C
Interferon Alfa Sensitivity in HIV/HCV Persons Before and After HIV Meds
The chief purpose of this research is to evaluate interferon alpha sensitivity and cell type specific levels of interferon receptor and interferon stimulated genes and proteins in HIV/ HCV (hepatitis C virus) coinfected persons…
- Trial name
- NCT01285050
- Testing
- Antiretroviral therapy (ART), raltegravir, Emtricitabine and tenofovir disoproxil fumarate
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Johns Hopkins University
HIV -1 Infection
A Clinical Trial to Look at the Safety and Immune Responses of the RNA-based Vaccine BNT168 in Adults Living With or Without HIV
This study will test a new ribonucleic acid (RNA)-based vaccine called BNT168 in adults living both with and without human immunodeficiency virus (HIV), to see how safe it is, how well it triggers the body's immune response and…
- Trial name
- NCT07698600
- Testing
- BNT168
- Where
- 4 sites in United States, South Africa
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- BioNTech SE