Oncologic DiseaseNCT07435597
Comparing the Effects of Art Therapy and Mandala Application on State Anxiety Levels in Chemotherapy Patients
A study testing Mandala therapy and Art therapy in people with Oncologic Disease and Chemotherapy, run by Atlas University at 1 site in Turkey (Türkiye).
Trial summary
The research is planned as a randomized controlled trial with a two-group (art-based flow drawing and mandala), pre-test, post-test design. Read more about this study
- Who is it for?
- Ages 18 years and olderHealthy volunteers can take part
- Conditions the study is for
- Oncologic Disease, Chemotherapy
- What is being tested?
- Mandala therapy and Art therapy
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 60 participants
- Where
- 1 siteTurkey (Türkiye)
- Study dates
- 18 Feb 2026to 30 May 2026
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Who may be able to join
- Must be 18 years of age or older
- Must be receiving chemotherapy treatment
- Must be willing to participate in the research
- Must be literate
- Must be able to speak and understand Turkish
Who cannot join
- -Having any speech or comprehension impairment
- Being treated with other forms of treatment
- Having any accompanying psychiatric diagnosis
- Using any psychiatric medication
- Being enrolled in another program using a similar method could affect the study's outcome
Trial locations and contacts
1 site in 1 country.
Turkey (Türkiye)1 site
Basaksehir Cam Sakura Hospital
Istanbul, Istanbul, 34000
About this study
Official title: Comparing the Effects of Art Therapy and Mandala Application on State Anxiety Levels in Chemotherapy Patients: A Randomized Controlled Study
The research is planned as a randomized controlled trial with a two-group (art-based flow drawing and mandala), pre-test, post-test design.
Read the detailed description
This study aims to compare the effects of the "Dance of the Pen" (art-based flow drawing) and mandala activities on state anxiety in patients undergoing chemotherapy and to evaluate intervention satisfaction. The research is planned as a randomized controlled trial with a two-group, pre-test, post-test design. The study will be conducted in two hospitals in Istanbul with a total of 60 participants. The intervention group will receive the "Dance of the Pen" and mandala activities. Randomization will be based on the patients' chemotherapy session days, and the study will be conducted as a single-blind study. Data will be collected using a Personal Information Form, the State Anxiety Scale (STAI-I), and a Distress Thermometer. Interventions will be applied in structured sessions lasting approximately 30-60 minutes. The population of the study will consist of patients receiving chemotherapy at hospital, and those patients meeting the inclusion criteria will constitute the sample of the study. Participants will be informed about the study before the research begins. Those who agree to participate will be assigned to a randomized group and will undergo either the "Dance of the Pen" or "Mandala activity," both conducted as single-session interviews. Participants will complete a Personal Information Form and the STAI-I before the activity, and will also undergo the STAI-I and distress thermometer tests afterwards.
- Conditions
- Oncologic Disease, Chemotherapy
- Being tested
- Mandala therapy, Art therapy
- Keywords
- mandala, art therapy, oncology, chemotherapy
- Medical subject headings
- Neoplasms
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Mandala therapyOther
Patients will be given a file containing mandala designs, and they will be asked to color the design of their choice with their preferred colored pencils (pastel, crayon, marker) throughout the treatment.
Art therapyOther
During chemotherapy, the patient will be given a pen to hold with their eyes closed and asked to draw on a blank piece of paper according to the instructions. Afterwards, their drawing will be analyzed and interpreted.
| Study group | Role | What they receive |
|---|---|---|
| Mandala | Experimental | Patients will be given a file containing mandala designs, and they will be asked to color the design of their choice with their preferred colored pencils (pastel, crayon, marker) throughout the treatment. Receives: Other: Mandala therapy |
| Art therapy | Experimental | During chemotherapy, the patient will be given a pen and will be played music. Following instructions, they will be asked to draw on the paper with their eyes closed and then interpret the drawing. Receives: Other: Art therapy |
| Control group | No intervention | Participants will only receive the clinical procedure. The clinical procedure will be an information session about the treatment. |
What is being measured
The primary outcome is the main question the study is designed to answer.
State anxiety scale
The State Anxiety Scale will be administered prior to the intervention, followed by randomly assigned art therapy or mandala practice. The State Anxiety Scale and distress thermometer will be administered again after the intervention is completed. A high score on the State Anxiety Scale indicates high anxiety levels.
Measured: 6 months
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted27 Feb 2026
- Study start18 Feb 2026
- Primary completion30 May 2026
- Study completion30 May 2026
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Oncologic DiseaseStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Supportive care
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Triple blind
- Who is masked
- Participant, Investigator, Outcomes assessor
- Enrolment
- 60 participants (actual)
Sponsor and investigators
- Lead sponsor
- Atlas University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Dilek Baykal, Atlas University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07435597
- Sponsor's protocol ID
- Atlas University
- Status last verified
- Jun 2026
- First submitted
- 18 Feb 2026
- Last updated
- 18 Jun 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 18 Jun 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Comparing the Effects of Art Therapy and Mandala Application on State Anxiety Levels in Chemotherapy Patients: A Randomized Controlled Study
- ClinicalTrials.gov ID
- NCT07435597
- Acronym / sponsor ID
- Atlas University
- Conditions
- Oncologic Disease, Chemotherapy
- Keywords
- mandala, art therapy, oncology, chemotherapy
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 60 participants (actual)
- Lead sponsor
- Atlas UniversityUniversity, hospital or other
- Study start
- 18 Feb 2026 (actual)
- Primary completion
- 30 May 2026 (actual)
- Study completion
- 30 May 2026 (actual)
- First posted
- 27 Feb 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The research is planned as a randomized controlled trial with a two-group (art-based flow drawing and mandala), pre-test, post-test design.
Detailed description
This study aims to compare the effects of the "Dance of the Pen" (art-based flow drawing) and mandala activities on state anxiety in patients undergoing chemotherapy and to evaluate intervention satisfaction. The research is planned as a randomized controlled trial with a two-group, pre-test, post-test design. The study will be conducted in two hospitals in Istanbul with a total of 60 participants. The intervention group will receive the "Dance of the Pen" and mandala activities. Randomization will be based on the patients' chemotherapy session days, and the study will be conducted as a single-blind study. Data will be collected using a Personal Information Form, the State Anxiety Scale (STAI-I), and a Distress Thermometer. Interventions will be applied in structured sessions lasting approximately 30-60 minutes. The population of the study will consist of patients receiving chemotherapy at hospital, and those patients meeting the inclusion criteria will constitute the sample of the study. Participants will be informed about the study before the research begins. Those who agree to participate will be assigned to a randomized group and will undergo either the "Dance of the Pen" or "Mandala activity," both conducted as single-session interviews. Participants will complete a Personal Information Form and the STAI-I before the activity, and will also undergo the STAI-I and distress thermometer tests afterwards.
Study design
- Primary purpose
- Supportive care
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Triple blind (participant, investigator, outcomes assessor)
- Number of arms
- 3
| Arm | Type | Receives |
|---|---|---|
| Mandala | Experimental | Other: Mandala therapyPatients will be given a file containing mandala designs, and they will be asked to color the design of their choice with their preferred colored pencils (pastel, crayon, marker) throughout the treatment. |
| Art therapy | Experimental | Other: Art therapyDuring chemotherapy, the patient will be given a pen and will be played music. Following instructions, they will be asked to draw on the paper with their eyes closed and then interpret the drawing. |
| Control group | No intervention | –Participants will only receive the clinical procedure. The clinical procedure will be an information session about the treatment. |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (5 listed)
- Must be 18 years of age or older
- Must be receiving chemotherapy treatment
- Must be willing to participate in the research
- Must be literate
- Must be able to speak and understand Turkish
Key exclusion criteria (5 listed)
- -Having any speech or comprehension impairment
- Being treated with other forms of treatment
- Having any accompanying psychiatric diagnosis
- Using any psychiatric medication
- Being enrolled in another program using a similar method could affect the study's outcome
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Mandala therapyPatients will be given a file containing mandala designs, and they will be asked to color the design of their choice with their preferred colored pencils (pastel, crayon, marker) throughout the treatment. | Other | Mandala |
| Art therapyDuring chemotherapy, the patient will be given a pen to hold with their eyes closed and asked to draw on a blank piece of paper according to the instructions. Afterwards, their drawing will be analyzed and interpreted. | Other | Art therapy |
Primary outcome
State anxiety scale
Time frame: 6 months
The State Anxiety Scale will be administered prior to the intervention, followed by randomly assigned art therapy or mandala practice. The State Anxiety Scale and distress thermometer will be administered again after the intervention is completed. A high score on the State Anxiety Scale indicates high anxiety levels.
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 18 Jun 2026.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Mandala therapy and Art therapy in people with Oncologic Disease and Chemotherapy, run by Atlas University at 1 site in Turkey (Türkiye).
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 5 inclusion and 5 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 18 Jun 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
State anxiety scale (time frame: 6 months). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 18 Jun 2026.