Clinical trials: AIDS-related Kaposi Sarcoma
Sarcoma, Kaposi, HIV Infections
A Study of ALRT1057 in Patients With AIDS-Related Kaposi's Sarcoma
The purpose of this study is to see if ALRT1057 is safe and effective in treating patients with AIDS-related Kaposi's sarcoma (KS).
- Trial name
- NCT00002188
- Testing
- Alitretinoin
- Volunteers
- 27 people
- Sponsor
- Anderson Clinical Research
Cancer
Thalidomide and Docetaxel in Treating Patients With Advanced Cancer
RATIONALE: Thalidomide may stop the growth of cancer by stopping blood flow to the tumor. Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die.
- Trial name
- NCT00049296
- Testing
- docetaxel, thalidomide
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Case Comprehensive Cancer Center
Sarcoma
Valproic Acid in Treating Patients With Kaposi's Sarcoma
RATIONALE: Valproic acid may help stop the growth of Kaposi's sarcoma cells by blocking the enzymes necessary for tumor cell growth.
- Trial name
- NCT00075777
- Testing
- valproic acid
- Where
- 13 sites in United States
- Volunteers
- 19 people
- Sponsor
- AIDS Malignancy Consortium
Sarcoma, Kaposi, HIV Infections
Phase II Study of Zidovudine and Recombinant Alpha-2A Interferon in the Treatment of Patients With AIDS-Associated Kaposi's Sarcoma
To determine the safety and effectiveness of combining zidovudine (AZT) and interferon alfa-2a (IFN-A2a) in a treatment for Kaposi's sarcoma (KS) in patients who have AIDS.
- Trial name
- NCT00000687
- Testing
- Interferon alfa-2a, Zidovudine
- Where
- 9 sites in United States
- Volunteers
- 60 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
HIV-Associated Malignant Neoplasm, HIV Infections
Use of a Screening Tool to Describe HIV-Related Cancer Burden and Patient Characteristics in the AMC
This study is being done to understand how many people with HIV (PWH) present for cancer care across the AIDS Malignancy Consortium in the United States and if there are reasons that some PWH choose to participate, or not in…
- Conditions
- HIV-Associated Malignant Neoplasm, HIV Infections, Cancer, AIDS Related Lymphoma
- Trial name
- NCT05510908
- Testing
- Non-Interventional, Non-Interventional Follow-up
- Where
- 16 sites in United States, Puerto Rico
- Volunteers
- 460 people
- Sponsor
- AIDS Malignancy Consortium
Sarcoma, Kaposi, HIV Infections
A Phase I Study of AZT and Human Interferon Alpha (Recombinant Alpha-2A and Lymphoblastoid) in the Treatment of AIDS-Associated Kaposi's Sarcoma
To evaluate the safety and toxicity of combination therapy for AIDS-associated Kaposi's sarcoma with zidovudine (AZT) and two kinds of interferon alpha.
- Trial name
- NCT00000725
- Testing
- Interferon alfa-2a, Zidovudine, Interferon alfa-n1
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Sarcoma, Kaposi, HIV Infections
SU5416 in Patients With AIDS-Related Kaposi's Sarcoma Who Have Not Responded to Treatment
The purpose of this study is to test the effectiveness of SU5416 in patients with AIDS-related Kaposi's sarcoma (KS).
- Trial name
- NCT00005931
- Testing
- SU5416
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- SUGEN
Sarcoma, Kaposi, HIV Infections
Phase I Study of Weekly Oral VP-16 for AIDS-Associated Kaposi's Sarcoma
To define the toxicity and maximum-tolerated dose of weekly oral etoposide (VP-16) in patients with AIDS-related Kaposi's sarcoma; to determine the clinical pharmacology of orally administered VP-16 in AIDS patients.
- Trial name
- NCT00000660
- Testing
- Etoposide
- Where
- 6 sites in United States
- Volunteers
- 24 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Epidemic Kaposi's Sarcoma, Recurrent Kaposi's Sarcoma
Interleukin-12 in Treating Patients With AIDS-Related Kaposi's Sarcoma
RATIONALE: Interleukin-12 may kill tumor cells by stopping blood flow to the tumor and by stimulating a person's white blood cells to kill their tumor cells.
- Trial name
- NCT00019188
- Testing
- interleukin-12
- Where
- United States
- Sponsor
- National Cancer Institute (NCI)
Sarcoma
Sirolimus in Treating Patients With HIV-Related Kaposi's Sarcoma
RATIONALE: Drugs used in chemotherapy, such as sirolimus, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing.
- Trial name
- NCT00450320
- Testing
- sirolimus
- Where
- 3 sites in United States
- Volunteers
- 7 people
- Sponsor
- AIDS Malignancy Consortium
Kaposi's Sarcoma, HIV Infections
Anti-Retrovirals for Kaposi's Sarcoma
The primary purpose of this study is to determine whether a protease inhibitor-based antiretroviral regimen is more efficacious than a non-nucleoside reverse transcriptase inhibitor-based antiretroviral regimen in promoting the…
- Trial name
- ARKS (NCT00444379)
- Testing
- Lopinavir/ritonavir plus Emtricitabine/Tenofovir versus Efavirenz plus Emtricitabine/Tenofovir
- Where
- Uganda
- Volunteers
- 224 people
- Sponsor
- University of California, San Francisco
HIV, Kaposi's Sarcoma
Specimen Collections From Participants With HIV Infection, KSHV Infection, Viral-Related Pre-malignant Lesions and Cancer
BACKGROUND: A number of important scientific advances can be made through the study of blood, bone marrow, tumor, or other tissue samples from patients with HIV infection, infection with Kaposi s sarcoma associated herpesvirus…
- Conditions
- HIV, Kaposi's Sarcoma, Lymphomas, Multicentric Castleman's Disease
- Trial name
- NCT00006518
- Where
- United States
- Volunteers
- 1,029 people
- Sponsor
- National Cancer Institute (NCI)
Sarcoma, Kaposi, HIV Infections
A Study of Targretin Capsules in Patients With AIDS-Related Kaposi's Sarcoma
The purpose of this study is to see if it is safe and effective to give Targretin capsules to patients with AIDS-related Kaposi's sarcoma (KS).
- Trial name
- NCT00002212
- Testing
- Bexarotene
- Where
- 3 sites in United States
- Volunteers
- 27 people
- Sponsor
- Ligand Pharmaceuticals
AIDS-related Kaposi Sarcoma, Classic Kaposi Sarcoma
Sunitinib Malate in Treating East African Patients With Kaposi Sarcoma
Sunitinib malate may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth and by blocking blood flow to the tumor.
- Trial name
- NCT00521092
- Testing
- sunitinib malate, laboratory biomarker analysis, pharmacological study
- Sponsor
- National Cancer Institute (NCI)
Sarcoma, Kaposi, HIV Infections
A Pilot Study of OPC-8212 (Vesnarinone) in Persons With AIDS-Related Kaposi's Sarcoma
To examine the safety and efficacy of two doses of vesnarinone in patients with AIDS-related Kaposi's sarcoma.
- Trial name
- NCT00002131
- Testing
- Vesnarinone
- Where
- 2 sites in United States
- Volunteers
- 28 people
- Sponsor
- Otsuka America Pharmaceutical
Sarcoma, Kaposi, HIV Infections
Photodynamic Therapy Clinical Trial For Cutaneous AIDS-Related Kaposi's Sarcoma Study Summary.
To determine the objective tumor response and remission rate of AIDS-related Kaposi's sarcomas (KS) following a single dose of tin ethyl etiopurpurin (SnET2) followed by photodynamic therapy (PDT).
- Trial name
- NCT00002167
- Testing
- Tin ethyl etiopurpurin
- Where
- 6 sites in United States
- Volunteers
- 78 people
- Sponsor
- Clinical Solutions
Lymphoma, Sarcoma
Altretamine and Etoposide in Treating Patients With HIV-Related Cancer
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells.
- Trial name
- NCT00002936
- Testing
- altretamine, etoposide
- Where
- United States
- Sponsor
- Roswell Park Cancer Institute
AIDS-related Kaposi Sarcoma, HIV Infection
A Phase II Trial of COL-3 in Patients With HIV Related Kaposi's Sarcoma
COL-3 may stop the growth of cancer by stopping blood flow to the tumor. Randomized phase II trial to compare the effectiveness of two different regimens of COL-3 in treating patients who have HIV-related Kaposi's sarcoma.
- Trial name
- NCT00020683
- Testing
- incyclinide, laboratory biomarker analysis
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- National Cancer Institute (NCI)
Sarcoma, Kaposi, HIV Infections
The Safety and Effectiveness of Ritonavir in the Treatment of HIV-Related Kaposi's Sarcoma
To evaluate the safety and anti-Kaposi's sarcoma activity of ritonavir.
- Trial name
- NCT00002366
- Testing
- Ritonavir
- Where
- 2 sites in Australia
- Sponsor
- Abbott
Sarcoma
EMD 121974 in Treating Patients With HIV-Related Kaposi's Sarcoma
Phase I trial to study the effectiveness of EMD 121974 in treating patients who have HIV-related Kaposi's sarcoma. EMD 121974 may stop the growth of Kaposi's sarcoma by stopping blood flow to the tumor.
- Trial name
- NCT00006222
- Testing
- cilengitide
- Where
- 3 sites in United States
- Volunteers
- 30 people
- Sponsor
- National Cancer Institute (NCI)