Clinical trials: AI Chatbot
Major Depressive Disorder
Optimize and Predict Antidepressant Efficacy for Patient With MDD Using Multi-omics Analysis and AI-predictive Tool
OPADE is a non-profit, observational, multicenter, open-label study aimed at defining personalized treatment for Major Depressive Disorder (MDD).
- Trial name
- OPADE (NCT06550037)
- Where
- Italy
- Volunteers
- 350 people
- Sponsor
- Alessio Fasano
Cardiovascular-kidney-metabolic Syndrome
AI Chatbot-Enabled ePRO Monitoring and Nurse-Led Self-Management for Early-Stage Cardiovascular-Kidney-Metabolic Syndrome
This randomized controlled trial will evaluate the effectiveness of an AI chatbot-enabled electronic patient-reported outcome (ePRO) monitoring and nurse-led self-management intervention for adults with early-stage…
- Trial name
- NCT07577284
- Testing
- AI chatbot-enabled nurse-led program., Usual Care
- Where
- Taiwan
- Volunteers
- 80 people
- Sponsor
- Taipei Medical University
Telephone Hotlines, AI Chatbot
Comparing the Effectiveness of AI Chatbot with That of Telephone Hotline
The COVID-19 pandemic has significantly impacted the wellbeing of people in Hong Kong, leading to social distancing policies and changes in healthcare service utilization.
- Trial name
- AI chatbot (NCT06621134)
- Testing
- AI Chatbot, Telephone hotline
- Where
- Hong Kong
- Volunteers
- 48 people
- Sponsor
- The University of Hong Kong
Head and Neck Cancer
An Oncology Nurse AI Agent to Reduce Cancer Distress During Radiotherapy
The goal of this clinical trial is to assess the effectiveness of the Digi-Coach chatbot for reducing physical and psychological distress in people undergoing radiotherapy for head and neck cancer.
- Trial name
- Digi-Coach (NCT06636188)
- Testing
- Digi-Coach Chatbot
- Where
- 2 sites in Hong Kong
- Volunteers
- 138 people
- Sponsor
- The University of Hong Kong
Osteo Arthritis Knee and Hip, Artificial Intelligence (AI)
Comparing Physician and Artificial Intelligence Chatbot Responses to Frequently Asked Questions From Osteoarthritis Patients
This study aimed to compare the patient acceptability (preference, length, and difficulty) and accuracy of Chat-Generative Pre-Trained Transformer (ChatGPT) responses to questions from people with osteoarthritis (OA) with…
- Conditions
- Osteo Arthritis Knee and Hip, Artificial Intelligence (AI), Acceptability, Accuracy
- Trial name
- PARTICIPATE (NCT07202286)
- Where
- Netherlands
- Volunteers
- 286 people
- Sponsor
- Canisius-Wilhelmina Hospital
Influenza Vaccines
Vaccine Chatbot for Improving Influenza Vaccination Uptake
This study aims to assess the impact of a vaccine chatbot on improving influenza vaccination uptake among children aged between 6 and 59 months through a cluster randomized trial.
- Trial name
- NCT06657573
- Testing
- An AI-enabled chatbot tailored for influenza vaccine consultation
- Where
- China
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Fudan University
Parkinson Disease, Occupational Therapy Students
Effect of AI Chatbot-Assisted Versus Traditional Case-Based Learning on Clinical Reasoning in Occupational Therapy Students: A Study on Parkinson's Disease
This study aims to examine whether using an artificial intelligence (AI) chatbot can enhance occupational therapy students' learning during a case-based activity focused on Parkinson's disease.
- Conditions
- Parkinson Disease, Occupational Therapy Students, Clinical Reasoning, Neurologic Rehabilitation
- Trial name
- AI-PD-OT25 (NCT07045077)
- Testing
- AI Chatbot-Assisted Case-Based Learning, Traditional Case-Based Learning with Standard Materials
- Where
- Turkey (Türkiye)
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Ceyhun Türkmen
Cancer, Financial Toxicity
SAFE.AI: Developing and Testing an AI-based Hybrid Chatbot for Financial Empowerment in Rural Cancer Care
This is a randomized, two-arm, parallel-group pilot trial investigating a new chatbot tool designed to support cancer patients and caregivers, particularly those in rural communities.
- Trial name
- NCT07410689
- Testing
- Rule-Based Chatbot, Hybrid Chatbot
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Utah
Healthy Lifestyle
A Pilot Randomized Controlled Trial of Chatbot Use in Older Adults for Lifestyle Change
The purpose of this study is to evaluate the acceptability and preliminary effectiveness of a smartphone-delivered AI-based chatbot in promoting healthy dietary behavior and physical activity participation among older adults.
- Trial name
- NCT06901037
- Testing
- A chatbot-based intervention
- Where
- Hong Kong
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Artificial Intelligence (AI), Electronic Fetal Monitoring
Chatbot About Electronic Fetal Monitoring
The study aims to investigate the effect of using artificial intelligence Chatbot education about electronic fetal monitoring on maternity nursing students' performance. The aim will be achieved through the following, 1.
- Conditions
- Artificial Intelligence (AI), Electronic Fetal Monitoring, Nursing Students
- Trial name
- NCT07051343
- Testing
- designed artificial intelligence Chatbot education about electronic fetal monitoring, traditional teaching method
- Where
- Egypt
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Cardiovascular Diseases, Lifestyle Factors
Using AI Text Messaging to Improve AHA's Life's Essential 8 Health Behaviors
The goal of our pragmatic clinical trial is to compare how well three different strategies might do to reduce risk factors for cardiovascular disease in patients experiencing health disparities.
- Trial name
- NCT06324981
- Testing
- Generic text messages, Interactive AI chatbot text messaging, Proactive pharmacist support
- Where
- 3 sites in United States
- Volunteers
- 2,100 people
- Sponsor
- University of Colorado, Denver
Cannabis Use Disorder, Anxiety
Use of a Generative AI (Gen-AI) Chatbot for Anxiety and Depression Among Persons With Cannabis Use
The goal of this clinical trial is to learn if Therabot-CALM (Cannabis, Anxiety, Low Mood) has acceptability among users and could work to improve the symptoms of persons with cannabis use disorder and anxiety and/or depression.
- Conditions
- Cannabis Use Disorder, Anxiety, Depression, Anxiety, Depression - Major Depressive Disorder
- Trial name
- NCT06920238
- Testing
- Therabot-CALM
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Trustees of Dartmouth College
HPV Vaccination Intent
Conversations With AI Chatbots Increase Short-Term Vaccine Intentions But Do Not Outperform Standard Public Health Messaging
The goal of this clinical trial is to test whether short conversations with large language model (LLM) chatbots can persuade vaccine-hesitant parents to vaccinate their children against human papillomavirus (HPV).
- Trial name
- NCT07132125
- Testing
- Default-style LLM chatbot, Conversational-style LLM chatbot, Public health informational materials
- Where
- United States
- Volunteers
- 930 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Peri-Implant Mucositis, Peri-implantitis
Impact of an AI-Based Chatbot on Implant Patient Management: RCT
Background: Dental implant therapy is a well-established and predictable procedure for replacing missing teeth, with high long-term survival rates.
- Conditions
- Peri-Implant Mucositis, Peri-implantitis, Peri-Implant Health, Peri-implant Inflammation
- Trial name
- NCT07300657
- Testing
- AI Chatbot, Standard Oral Hygiene Education
- Where
- Italy
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- University of Catania
Chronic Kidney Disease
Development of a Precision Nutrition Expert System Combining AI Dietary Image Recognition and Big Data Analysis: A Case Study on Kidney Disease
The goal of this interventional study is to evaluate a smartphone-based precision nutrition system for patients with chronic kidney disease (CKD). The main questions it aims to answer are: 1.
- Trial name
- CKDCare (NCT07829991)
- Testing
- CKDcare
- Where
- Taiwan
- Volunteers
- 50 people
- Sponsor
- China Medical University Hospital
HPV Vaccination Rates, HPV Vaccine Awareness
Effectiveness of Large Language Model-Based Chatbot Among Female University Stdents in Improving HPV Vaccine Awareness, Intention and Vaccination Rates
This is an interventional study targeting female university students. The primary objective of the study is to evaluate the effectiveness of a vaccine chatbot in improving HPV vaccination rates.
- Conditions
- HPV Vaccination Rates, HPV Vaccine Awareness, HPV Vaccination Intention
- Trial name
- NCT07351604
- Testing
- Scientific videos, Vaccine chatbot
- Volunteers
- 18,000 people, healthy volunteers welcome
- Sponsor
- Xiamen University
Nursing Education, Clinical Decision-making
Effect of AI-Supported Virtual Patient Chatbot Training on Nursing Students' Self-Perceived Clinical Decision-Making and Gynecological Cancer Knowledge
This randomized controlled trial evaluated the effects of structured case-based training delivered through an artificial intelligence-supported educational virtual patient chatbot platform on nursing students' gynecological…
- Conditions
- Nursing Education, Clinical Decision-making, Gynecologic Cancers, Chatbot-Based Training
- Trial name
- NCT07806396
- Testing
- AI-Supported Educational Virtual Patient Chatbot Platform
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Sakarya University
Caregivers
Supporting Care Partners' Well-Being With Artificial Intelligence (AI) Chatbots
This study is being completed to test an AI therapy chatbot application called Earkick to see whether it is feasible and acceptable in supporting care partners who support individuals living with dementia.
- Trial name
- NCT07145723
- Testing
- Earkick app
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- University of Michigan
Digital Health Literacy, AI Chatbot
Artificial Intelligence and Digital Health Literacies Among Older Adults: A Mixed-method Pilot Intervention Study
The goal of this pilot study is to determine the feasibility and to learn if a training program called E2NGAGE-Literacy (Empowering Elders in Navigating Generative AI for Greater E-health Literacy) can potentially help older…
- Conditions
- Digital Health Literacy, AI Chatbot, Aged 60 Years or Older
- Trial name
- NCT07881510
- Testing
- AI and digital health literacy program (E2NGAGE-Literacy)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
AI Companionship
How Do Artificially Intelligent Companions Influence Psychological Outcomes?
This randomized longitudinal study examines how interacting with an artificially intelligent (AI) companion affects psychological well-being, social experiences, and interpersonal attitudes and behaviors over time.
- Trial name
- NCT07858279
- Testing
- AI Companion Interaction
- Where
- United States
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- University of Michigan