Clinical trials: ACT
Psychological Well Being, Psychological Flexibility
Finding With Nature: A Study Testing Nature-Based Support for Family Caregivers Aged 65 and Over
This research project investigates the effects of a nature-based programme (Finding with Nature, FWN), on psychological well-being, functioning, and nature connectedness among older adults (65 and older) who provide care for…
- Conditions
- Psychological Well Being, Psychological Flexibility, Physical Functioning, Burden, Caregiver
- Trial name
- FWN (NCT07821970)
- Testing
- Finding with Nature Programme
- Volunteers
- 350 people
- Sponsor
- JAMK University Of Applied Sciences
Menopause, Anxiety
Internet-Delivered Cognitive Behaviour Therapy for Women with Perimenopausal Anxiety
The goal of this clinical trial is to design an online Cognitive Behavioural Therapy (CBT) and Acceptance Commitment Therapy (ACT) program and to learn if it can treat anxiety in women transitioning into menopause…
- Conditions
- Menopause, Anxiety, Depressive/Anxiety Symptoms, Perimenopause
- Trial name
- NCT06865066
- Testing
- e-CBT
- Where
- 2 sites in Canada
- Volunteers
- 25 people
- Sponsor
- Dr. Nazanin Alavi
Healthy
A Study to Learn How Different Amounts of the Study Medicine Called PF-07940369 Are Tolerated and Act in the Body in Healthy Adults.
The purpose of the study is to evaluate the safety, tolerability, and Pharmacokinetics (Pharmacokinetics [PK] to better understand how the drug is changed and eliminated from your body after you take it) of single ascending oral…
- Trial name
- NCT06532383
- Testing
- PF-07940369
- Where
- Belgium
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Pfizer
Falciparum Malaria
Pyronaridine - Artesunate (3:1) Versus Mefloquine Plus Artesunate in Plasmodium Falciparum Malaria Patients
The primary objective of this phase III clinical study is to compare the efficacy and safety of the fixed combination of pyronaridine artesunate (Pyramax®, PA) with that of the combination of mefloquine plus artesunate (MQ + AS)…
- Trial name
- NCT00403260
- Testing
- Pyronaridine - artesunate, Mefloquine plus artesunate
- Where
- 9 sites in Burkina Faso, Cambodia and 5 more
- Volunteers
- 1,271 people
- Sponsor
- Medicines for Malaria Venture
Asthma
To Determine the Validity of the ACT in an Adolescent Population With Persistent Asthma
To determine the measurement profiles of the asthma control test (ACT) in an adolescent population with persistent asthma.
- Trial name
- ACT2 (NCT02662413)
- Testing
- Validation of Asthma Control Questionnaire
- Where
- 2 sites in United States
- Volunteers
- 37 people
- Sponsor
- University of North Carolina, Chapel Hill
Detention Under the Mental Health Act
Advance Choice Document Implementation
Advance Choice Documents (ACDs) are statements of preferences for mental health care and treatment made when service users have capacity to do so. This is done with their care team and others as desired, e.g.
- Trial name
- ACDI (NCT07284368)
- Testing
- Advance Choice Document Implementation
- Where
- United Kingdom
- Volunteers
- 374 people
- Sponsor
- King's College London
Alpha-1 Antitrypsin Deficiency
The Alpha-1 Foundation's and University of Florida's Alpha-1 Coded Testing (ACT) Study
The Alpha-1 Coded Testing (ACT) Study was established to study genetic testing and outcomes of individuals at risk for alpha-1 antitrypsin deficiency.
- Trial name
- ACT (NCT00500123)
- Testing
- Alpha-1 Antitrypsin Genotype
- Where
- United States
- Volunteers
- 50,000 people, healthy volunteers welcome
- Sponsor
- University of Florida
Advanced Malignant Solid Tumor
Neoantigen Reactive T Cells Combined With SHR-1210 for Chinese Patients With Advanced Refractory Solid Tumors
The purpose of this study is to see the safety and efficient of neoantigen reactive T cells (NRTs) combined with programmed cell death-1(PD-1) inhibitor（SHR-1210）in the treatment of Chinese patients with advanced refractory solid…
- Trial name
- NRT-01 (NCT03171220)
- Testing
- Neoantigen Reactive T Cells(NRTs), SHR-1210, Fludarabine
- Where
- China
- Volunteers
- 40 people
- Sponsor
- The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
Coronary Artery Disease, Ischemic Heart Disease
The Randomized OPTIMAL-ACT Trial
The purpose of this study is to find the ideal range of the activated clotting time (ACT) during percutaneous coronary intervention (PCI) that is associated with lowering the rate of undesirable medical outcomes
- Conditions
- Coronary Artery Disease, Ischemic Heart Disease, Anticoagulant-induced Bleeding, Coronary Syndrome
- Trial name
- NCT03772613
- Testing
- Unfractionated heparin
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- Mayo Clinic
Burns
The Relationship of Rehabilitation Therapy Time To The Prevention of Burn Scar Contracture
This project will develop a descriptive database of patient information and patient outcomes. This database will be used to determine the association of time spent in rehabilitation and patient outcomes, to relate patient acuity…
- Trial name
- ACT (NCT01161810)
- Testing
- Routine post burn rehabilitation therapy
- Where
- 14 sites in United States
- Volunteers
- 386 people
- Sponsor
- American Burn Association
Hearing Voices When No One is Talking
ACT for Older Adults Who Hear Voices (HSCED)
Hearing voices (often referred to as "auditory hallucinations") is a common experience amongst the older adult population (those 65+ years of age) and can be associated with increased psychological distress.
- Trial name
- NCT06420024
- Testing
- Acceptance and Commitment Therapy
- Where
- 2 sites in United Kingdom
- Volunteers
- 2 people
- Sponsor
- University of Nottingham
Malaria, Pneumonia
Assessment of Use of Rapid Diagnostic Testing in the Context of Home Management With ACTs
This study is to assess the value of incorporating a malaria RDT based strategy in HMM. The primary activity of the study wil be a two armed cluster randomised trial in two study sites in Uganda, one in Ghana and one in Burkina…
- Trial name
- NCT00720811
- Testing
- Artemether-lumefantrine combination, amoxycillin, paracetamol
- Where
- 4 sites in Burkina Faso, Ghana and 1 more
- Volunteers
- 6,456 people
- Sponsor
- Mbarara University of Science and Technology
Post Traumatic Headache
Eary Infusion of Eptinezumab for TreatmEnt of ACute Post-Traumatic Headaches (ELITE-ACT)
Most individuals with mild traumatic brain injury (mTBI) experience post-traumatic headaches (PTH). Of PTH, 50% present with a migraine phenotype which is the most disabling type of PTH.
- Trial name
- NCT07191145
- Testing
- Eptinezumab
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- Sunnybrook Health Sciences Centre
Oral Mucositis Due to Radiation
Ectoin® Mouth Wash (EML03) in the Prevention and Treatment of Radiation-induced Oral Mucositis
This prospective non-interventional comparator study is to collect data on the clinical effectiveness and compliance of Ectoin® Mouth Wash solution (EML03) and to proof superiority to a well-established medical device on the…
- Trial name
- NCT03932292
- Testing
- Ectoin Mouth Wash, Supersaturated solution of calcium and phosphate ions
- Where
- Hungary
- Volunteers
- 52 people
- Sponsor
- Bitop AG
Breast Cancer Female
The Psychology Intervention on Disease Acceptance and Quality of Life in Breast Cancer Patients
The psychological rehabilitation of breast cancer patients plays an important role in the whole process of disease rehabilitation.
- Trial name
- NCT05327153
- Testing
- Acceptance and Commitment Therapy
- Where
- Malaysia
- Volunteers
- 90 people
- Sponsor
- Universiti Sains Malaysia
Fever, Malaria
Effectiveness Of Rapid Diagnostic Tests in the New Context of Low Malaria Endemicity in Zanzibar
The purpose of this study is to study the effectiveness of wide scale RDT use at the primary health care level in previously high malaria endemic area during malaria pre-elimination phase for improved targeting of anti-malarial…
- Trial name
- RDTACT (NCT01002066)
- Where
- Tanzania
- Volunteers
- 3,890 people
- Sponsor
- Karolinska University Hospital
Autism Spectrum Disorder, Attention Deficit Hyperactivity Disorder
Pai.ACT - An Artificial Intelligence Driven Chatbot Assisted ACT
Limited psychological support for parents of children with special needs in Hong Kong can profoundly impact the child rehabilitation process and the well-being of parent-child dyads.
- Conditions
- Autism Spectrum Disorder, Attention Deficit Hyperactivity Disorder, Neurodevelopmental Disorders, Intellectual Disability
- Trial name
- NCT06086951
- Testing
- Pai.ACT Group, Control Group
- Where
- 2 sites in Hong Kong
- Volunteers
- 60 people
- Sponsor
- Chinese University of Hong Kong
Access to Care, Psychological Distress
ACT Workshops: A Novel Delivery Modality to Increase Access to Care for Rural Veterans
This study investigates access, effectiveness, and acceptability of 1-day ACT workshops on problematic mental health symptoms.
- Trial name
- NCT05196464
- Testing
- Acceptance and Commitment Therapy (ACT) Workshop, Treatment as usual (TAU)
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- Syracuse VA Medical Center
Burnout, Clinical Burnout
Comparing ACT, Recuperation, and ACT Plus Vocational Support for Clinical Burnout
This study compares three different online psychological treatments for people with clinical burnout (stress-related exhaustion) who are on sick leave or have major difficulties coping at work or in daily life.
- Conditions
- Burnout, Clinical Burnout, Exhaustion Disorder
- Trial name
- NCT07272421
- Testing
- ACT, Recuperation, Vocational support
- Where
- Sweden
- Volunteers
- 210 people
- Sponsor
- Uppsala University
Anger, Aggression
Anger Control Therapy (ACT) With RAGE-Control: An Outpatient Videogame-assisted Therapy for the Treatment of Anger
The purpose of this study is to determine whether adding an interactive biofeedback video game to anger control cognitive behavioral therapy is an effective and feasible treatment.
- Trial name
- NCT01551732
- Testing
- ACT, ACT with RAGE-Control
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Gonzalez-Heydrich, Joseph, M.D.