Clinical trials: ACL Repair
Anterior Cruciate Ligament Tear
Primary Anterior Cruciate Ligament Repair With and Without Lateral Extraarticular Tenodesis
The investigators aimed to compare the clinical results of primary repairs and Lateral Extraarticular Tenodesis applied with primary repairs in the treatment of proximal ACL tears.
- Trial name
- NCT05923710
- Testing
- Primary anterior cruciate ligament repair, Primary anterior cruciate ligament repair and lateral extraarticular tenodesis (LET) with iliotibial band
- Where
- Turkey (Türkiye)
- Volunteers
- 38 people
- Sponsor
- Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization
ACL Surgery, Pain Management
Efficacy of Methylprednisolone for Pain Control After ACL Repair
Opioids are commonly used after orthopedic surgery for pain control but have been shown to increase complications, surgeries, readmissions, and risk for opioid use disorder.
- Trial name
- NCT07158476
- Testing
- Meloxicam 15 mg, Medrol 4 MG Oral Tablet Includes Medrol Dosepak, Gabapentin 300 mg
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- St. Louis University
ACL Repair
The Effect of Pre-Operative Cryoneurolysis on Post-Operative Narcotic Consumption in Patients Undergoing Autograft ACL Reconstruction
The purpose of the research is to investigate the effect of preoperative Cryoneurolysis of the knee on postoperative pain management in patients undergoing autograft anterior cruciate ligament (ACL) reconstruction (a surgical…
- Trial name
- NCT06603051
- Testing
- Cryoneurolysis
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- Virtua Health, Inc.
Anesthesia
Oral Duloxetine as a Premedication for Postoperative Pain Control
The purpose of the study is to use duloxetine as premedication in Anterior cruciate ligament repair under spinal anesthesia and evaluate the effect on onset and duration of spinal anesthesia and postoperative pain control.
- Trial name
- NCT05050656
- Testing
- Duloxetine 60mg
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Ain Shams University
ACL Injury, Post Operative Pain
iPACK for Post-op Pain Following ACL Reconstruction
This study will consist of patients 12 years and older undergoing ACL reconstruction using a quadriceps or bone-patella tendon bone (BTB) graft.
- Trial name
- NCT05498870
- Testing
- Adductor Canal Block (ACB) Only, Adductor Canal Block (ACB) + iPACK Block
- Where
- United States
- Volunteers
- 82 people
- Sponsor
- Medical University of South Carolina
Anterior Cruciate Ligament Rupture, Surgery
ALL Ultrasound Predicts the Success of ACL Repair?
This case series evaluates whether patients with an anterior cruciate ligament (ACL) repair have better outcome if the anterolateral ligament (ALL) was repaired or not considering the ultrasound (US) pre-surgical recommendation.
- Trial name
- ALL_US (NCT04373408)
- Testing
- ACL repair without anterolateral repair, ACL repair with anterolateral repair
- Where
- Switzerland
- Volunteers
- 120 people
- Sponsor
- Adrien Schwitzguebel
Post Operative Pain
Analgesic Efficacy of Genicular Nerve Block Versus (IPack Block ) in Patients Undergoing (ACL) Repair
One of the most common injuries to the knee is an anterior cruciate ligament (ACL) sprain or tear due to trauma ACL damage is crippling and often requires repair with an arthroscopic method, which is an outpatient surgery.
- Trial name
- NCT06404658
- Testing
- Genicular nerve block
- Where
- Egypt
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Beni-Suef University
Torn Anterior Cruciate Ligament (Knee)
Use of Graft Tensioner Device in ACL (Knee) Repair
Compares tension of an ACL graft when using a commercial device vs. the tension of the graft applied by a physician during surgery.
- Trial name
- NCT00221273
- Testing
- ACL surgery
- Volunteers
- 130 people
- Sponsor
- University of British Columbia
Anterior Cruciate Ligament Tear
A Comparison of ACL Repair With BEAR Device vs. Autograft Patellar Tendon ACL Reconstruction
This study is designed to evaluate bridge-enhanced ACL restoration (BEAR), a new surgical technique for repairing knees injured by a tear of the anterior cruciate ligament (ACL) that promotes reattachment and healing of the ACL…
- Trial name
- BEAR-MOON (NCT03776162)
- Testing
- ACL Reconstruction (Bone Patellar Tendon Bone Graft), Bridge Enhanced ACL Restoration (BEAR)
- Where
- 6 sites in United States
- Volunteers
- 150 people
- Sponsor
- The Cleveland Clinic
Anterior Cruciate Ligament Tear
Anterior Cruciate Ligament Reconstruction Hybrid Remnant Repair
Patients between 14-60 years of age who will undergo an anterior cruciate ligament (ACL) reconstruction between Nov 1, 2021- Dec 31, 2023, will have their charts reviewed be approached in clinic when the surgery is scheduled…
- Trial name
- NCT05494073
- Testing
- ACL Reconstruction with Hybrid Remnant Repair, ACL Reconstruction without Hybrid Remnant Repair
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Henry Ford Health System
Anterior Cruciate Ligament Injuries
Feasibility of a RCT That Compares Immediate Versus Optional Delayed Surgical Repair After ACL Injury
Currently, most patients with an anterior cruciate ligament (ACL) injury undergo surgery. There is a general belief that surgical reconstruction is necessary to return to sport safely and to limit premature knee osteoarthrosis or…
- Trial name
- IODA (NCT04408690)
- Testing
- Immediate anterior cruciate ligament reconstruction, Rehabilitation, Optional delayed anterior cruciate ligament reconstruction
- Where
- 2 sites in Belgium
- Volunteers
- 29 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament Rupture
Tendon-Bone Versus All-Soft-Tissue for ACL Reconstruction: A Patient-Blinded Randomized Clinical Trial
In primary pediatric Anterior cruciate ligament (ACL) reconstruction, the quadriceps tendon with either tendon and patellar bone or an all-tendon graft is commonly employed.
- Conditions
- Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament Rupture, Anterior Cruciate Ligament Tear
- Trial name
- NCT04039971
- Testing
- ACL Reconstruction
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- University of Colorado, Denver
Anterior Cruciate Ligament (ACL) Tear, Anterior Cruciate Ligament Reconstruction
Clinical and Functional Outcomes After ACL Reconstruction Versus Primary Repair
The anterior cruciate ligament (ACL) is the primary structure responsible for controlling anterior-posterior translation and rotational stability of the knee joint.
- Conditions
- Anterior Cruciate Ligament (ACL) Tear, Anterior Cruciate Ligament Reconstruction, Isokinetic Test
- Trial name
- NCT07318272
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Gazi University
ACL - Anterior Cruciate Ligament Deficiency, ACL Injury
Tourniquet Use in Anterior Cruciate Ligament Repair
The purpose of this study is to assess the intra-operative and post-operative effects of tourniquet use during ACL reconstruction. We hypothesize that: 1.
- Conditions
- ACL - Anterior Cruciate Ligament Deficiency, ACL Injury, ACL Tear
- Trial name
- NCT05931627
- Testing
- Patients undergoing ACL reconstruction with or without a tourniquet
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- OrthoCarolina Research Institute, Inc.
Anterior Cruciate Ligament Injury, Anterior Cruciate Ligament Tear
Bridge-Enhanced ACL Repair-Safety Study (BEAR Trial)
This study will assess the safety and early efficacy of a newly developed device, bridge-enhanced scaffold (MIACH™,) used to repair a torn anterior cruciate ligament (ACL.) Ten participants will undergo surgery with the new…
- Trial name
- BEAR (NCT02292004)
- Testing
- ACL Repair with MIACH Scaffold, Standard ACL Reconstruction
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Miach Orthopaedics
Rupture of Anterior Cruciate Ligament
Arthroscopic Primary Repair of the Anterior Cruciate Ligament (ACL)
A prospective cohort study that will be conducted at Sultan Qaboos University Hospital. It aims to determine the outcomes, in terms of, activity level, functional level, subjective knee function, range of motion, stability, and…
- Trial name
- NCT03510845
- Testing
- Arthroscopic ACL Primary Repair, Arthroscopic ACL Reconstruction
- Where
- Oman
- Volunteers
- 45 people
- Sponsor
- Sultan Qaboos University
Rupture
RetroBRACE - Clinical and Functional Outcomes 2 Years After Primary ACL Repair (Internal Bracing)
The purpose of this study is to quantify 2-year postoperative clinical and functional outcomes including side-to-side differences in gait function, balance, proprioception and muscle strength in patients treated by ACL repair…
- Trial name
- RetroBRACE (NCT03997071)
- Testing
- functional outcome measurement
- Where
- Switzerland
- Volunteers
- 38 people
- Sponsor
- University Hospital, Basel, Switzerland
Rehabilitative Nutrition for Muscle Recovery From ACL Reconstruction
Protein in Feeding Strategies to Accelerate Muscle Recovery From ACL Reconstruction
Musculoskeletal injury, particularly injuries requiring surgical repair, induce significant muscle atrophy, resulting in diminished physical function.
- Trial name
- NCT03492021
- Testing
- Diet Intervention_AP-CPT, Diet Intervention_PP-PPT
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- University of Connecticut
Meniscus Tear
Bridge-Enhanced ACL Repair (BEAR) in Meniscus Repair
The bridge-enhanced ACL repair (BEAR) implant is a collagen-based scaffold loaded with whole blood. It is designed to promote healing in the setting of intraarticular knee pathology.
- Trial name
- NCT06041763
- Testing
- Meniscal Repair Procedure, BEAR Implant
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- NYU Langone Health
ACL, Meniscus Lesion
THE EFFECT OF RAMP LESION REPAIR ON RETURN TO SPORTS IN ANTERIOR CRUCIATE LIGAMENT RECONSTRUCTION
Purpose/reason of the research: The anterior cruciate ligament (ACL) is an important ligament in maintaining knee function. In patients with anterior cruciate ligament (ACL) injury, concomitant intra-articular lesions are usually…
- Conditions
- ACL, Meniscus Lesion, Sport Injury
- Trial name
- NCT05048420
- Testing
- surgery
- Where
- Turkey (Türkiye)
- Volunteers
- 21 people
- Sponsor
- Medipol University