Clinical trials: medical devices
Neonatal Pain, Procedural Pain
Effect of ShotBlocker and Warm Gel Pack on Heel Stick Pain in Newborns
Newborns routinely undergo heel stick procedures for blood screening tests shortly after birth. Although the procedure is brief, it can cause pain, stress, and physiological changes.
- Trial name
- WARM-SHOT (NCT07921628)
- Testing
- ShotBlocker, Warm Gel Pack
- Where
- Turkey (Türkiye)
- Volunteers
- 147 people, healthy volunteers welcome
- Sponsor
- Istinye University
Diplegic Cerebral Palsy
Additional Effects on tDCS With AOT on Lower Limb Functions on Children With Diplegic CP
The goal of this clinical trial is to evaluate the therapeutic effects of combining active transcranial direct current stimulation (tDCS) with Action Observation Therapy (AOT) in pediatric patients diagnosed with spastic Cerebral…
- Trial name
- tDCS (NCT07921095)
- Testing
- Action Observation Therapy, Transcranial Direct Current Stimulation
- Where
- Pakistan
- Volunteers
- 40 people
- Sponsor
- Riphah International University
Brain Death, Respiration, Artificial
Miniature In-line Respirator
This first-in-human pilot study will test an investigational miniature breathing device called the Hope inVent. The device is a small, single-use, in-line respirator that connects to a breathing tube and uses compressed oxygen to…
- Trial name
- NCT07768215
- Testing
- Hope inVent
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- National Institutes of Health Clinical Center (CC)
Apnea of Prematurity
nCPAP-NAVA-Backup Versus Standard nCPAP for Severe Apnea in Preterm Infants ≤28 Weeks
The goal of this clinical trial is to determine whether nasal continuous positive airway pressure (nCPAP) with neurally adjusted ventilatory assist (NAVA) backup ventilation (nCPAP-NAVA-backup mode) reduces the rate of severe…
- Trial name
- NAVAPNEA (NCT07923604)
- Testing
- nCPAP-NAVA-backup mode, nCPAP mode
- Where
- Switzerland
- Volunteers
- 25 people
- Sponsor
- University Hospital, Geneva
Pediatric Acute Respiratory Failure
Regional Lung Ventilation During Prone Position in in Intubated Children
Mechanical ventilation can lead to pulmonary, diaphragmatic, and hemodynamic complications due to an increase in global and regional transpulmonary pressure.
- Trial name
- ChildProne-EIT (NCT07921745)
- Testing
- Thoracic electric impedance tomography to assed regional ventilation, Positive end-expiratory pressure (PEEP) trial titration, Collection of clinical Data
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Pre-myopia, Myopia
Managing Premyopia in Chinese Children Using Artificial Intelligence Assisted Defocus Incorporated Multiple Segments Based Spectacle Lens: a Randomized Controlled Clinical Trial
Pre-myopia refers to a condition in which children have not yet developed myopia but exhibit insufficient hyperopic reserve (≤ +0.75 D).
- Trial name
- NCT07765550
- Testing
- Artificial Intelligence Assisted DIMS based Spectacle Lens, Smartwatches
- Where
- China
- Volunteers
- 128 people
- Sponsor
- Shanghai Eye Disease Prevention and Treatment Center
Bronchiolitis
Respiratory Support and Treatment for Efficient and Cost-Effective Care
This project aims to answer the essential questions about the management of acute, pediatric respiratory illness, accelerate recovery from these all-too-common diseases, curb unnecessary costs of care, and demonstrate UPMC…
- Trial name
- REST EEC (NCT05909566)
- Testing
- Clinical Decision Support (CDS), HHFNC Weaning
- Where
- United States
- Volunteers
- 362 people
- Sponsor
- Christopher Horvat
Pulmonary Arteriovenous Malformations
Efficacy & Safety of LOBO™ Vascular Occlusion Device for Embolization of Pulmonary Arteriovenous Malformations
The goal of this clinical trial is to evaluate both the technical success and efficacy of using the LOBO™ device in patients undergoing embolization of Pulmonary Arteriovenous Malformations (PAVM).
- Trial name
- PAVM (NCT06735976)
- Testing
- PAVM Embolization, PAVM Embolization with a LOBO™ device
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of North Carolina, Chapel Hill
Intubation
AI-assisted Tracheal Intubation in Children
The aim of this study is to investigate whether the use of larynGuide™ provides accurate and reliable information regarding the position of the endotracheal tube following an intubation attempt in children.
- Trial name
- DOLPHIN (NCT07922434)
- Testing
- LarynGuide
- Where
- Switzerland
- Volunteers
- 110 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
ADHD - Attention Deficit Disorder With Hyperactivity, ADHD - Combined Type
AI-assisted Home-based Intervention for ADHD Children
The goal of this clinical trial is to evaluate the effectiveness of online diary platforms for socio-emotional learning training in children with attention deficit hyperactivity disorder (ADHD).
- Conditions
- ADHD - Attention Deficit Disorder With Hyperactivity, ADHD - Combined Type, ADHD - Inattentive Type
- Trial name
- NCT07922018
- Testing
- Generative artificial intelligence assisted diary platform home-based intervention, Consultations and psychoeducation on child emotional management
- Where
- Taiwan
- Volunteers
- 120 people
- Sponsor
- National Taiwan University Hospital
Myopia, Myopia Progressing
BRIGHT-LIGHT: Studying Red Light Therapy for Severe Short-Sightedness or Short-Sightedness That Worsens Despite Standard Treatment
Some children's short-sightedness (myopia) continues to worsen despite treatments such as atropine eye drops, myopia-control spectacles or contact lenses.
- Conditions
- Myopia, Myopia Progressing, Myopia Progression, Light
- Trial name
- BRIGHT LIGHT (NCT07923019)
- Testing
- Repeated low-level red-light (RLRL) therapy, Continued existing myopia treatment strategy
- Where
- 2 sites in Singapore
- Volunteers
- 40 people
- Sponsor
- Singapore National Eye Centre
Apthous Ulcer
Recurrent Aphthous Stomatitis Management in Children Using Diode Laser 980 Nanometer Versus Hyaluronic Acid Gel (RCT)
Thirty children with recurrent apthous ulcer will be divided into 3 groups of different treatment modalities to assess their effect on pain, ulcer size, healing and postoperative pain
- Trial name
- RCT (NCT07922681)
- Testing
- laser therapy, Hyaluronic acid group, Negative control group
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- National Research Centre, Egypt
Myelomeningocele, Spina Bifida
Transcutaneous Spinal Stimulation for Children and Youth With Spina Bifida
A study to use transcutaneous spinal cord stimulation to characterize sensorimotor deficits in a pediatric population of individuals with spina bifida.
- Trial name
- NCT06918119
- Testing
- Transcutaneous stimulation
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Mayo Clinic
Posttraumatic Stress Disorder
Ketamine-assisted Psychotherapy for Adolescent PTSD (KAP)
The objectives of this study are to investigate the feasibility, tolerability, and preliminary efficacy of repeated ketamine-assisted psychotherapy sessions in adolescents with severe posttraumatic stress disorder.
- Trial name
- NCT06378528
- Testing
- Ketamine, SmartSleep EEG recording headband
- Sponsor
- University of Wisconsin, Madison
Motor Disorders, Neuromuscular Diseases
Usability of the FTEXES Wearable Textile Platform for Functional Electrical Stimulation and EMG
FTEXES (Functionalized TEXtiles for Electrical Stimulation) is a wearable platform based on sensorized garments (Smart Pants and Smart T-shirt) with integrated textile electrodes for surface electromyography (EMG) recording and…
- Conditions
- Motor Disorders, Neuromuscular Diseases, Healthy Volunteers
- Trial name
- FTEXES (NCT07922980)
- Testing
- FTEXES wearable system
- Where
- Italy
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Politecnico di Milano
Dyslexia, Reading Disability
Brain Stimulation Paired With Structured Reading Instruction in Children With Dyslexia
This study investigates whether transcranial electrical stimulation (tES) delivered during structured reading instruction affects reading proficiency in children with developmental dyslexia and related reading disabilities.
- Trial name
- NCT07762365
- Testing
- Active transcranial electrical stimulation (tES)
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- General Neuro Inc.
Hearing Loss, Bilateral
Hearing Intervention Effects on Brain and Language Development in Children With Bilateral Mild Hearing Loss
This is a multicenter, prospective, randomized controlled clinical trial to evaluate the effects of hearing aid intervention on brain and language development in children with bilateral mild sensorineural hearing loss.
- Trial name
- HBD-RCT (NCT07774728)
- Testing
- Behind-the-ear (BTE) hearing aids, Hearing-care educational sessions
- Where
- 12 sites in China
- Volunteers
- 260 people
- Sponsor
- Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University
Amblyopia
Novel Amblyopia Treatment With Virtual Reality Games
The goal of this study is to compare the change in amblyopic eye acuity between treatment periods in children with amblyopia, aged 5-17 years.
- Trial name
- NCT06049459
- Testing
- Optical Correction, Therapeutic Dichoptic Virtual Reality Games
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Marjean Kulp
Survivors of Pediatric Brain Tumors, Pediatric Cancer
Facial Expression Awareness Training to Understand and Recognize Emotions
The purpose of this research is to find out if a computer-based treatment program, called FaceSay, is a feasible and effective intervention for survivors of pediatric brain tumors (SPBT).
- Trial name
- FEATURE (NCT07923370)
- Testing
- FaceSay, SuccessMaker Reading
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Children's Hospital of Philadelphia
Apnea Infant
Clinical Assessment of the BreathAlert Device in Monitoring Apneic Episodes
A team of researchers at Rice University in partnership with clinicians at Queen Elizabeth Central Hospital created BreathAlert, a low cost battery-powered monitor that detects and corrects apnea.
- Trial name
- NCT07704320
- Testing
- BreathAlert (low cost respiratory rate and apnea monitor)
- Where
- Malawi
- Volunteers
- 60 people
- Sponsor
- William Marsh Rice University
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