Clinical trials: Treatment as usual
Nonsuicidal Self-Injury, Self-Injurious Behavior
Naltrexone for Nonsuicidal Self-Injury
This randomized, double-blinded, placebo-controlled clinical trial aims to evaluate the efficacy and safety of naltrexone in reducing nonsuicidal self-injurious behavior among individuals with nonsuicidal self-injury.
- Trial name
- NCT07641283
- Testing
- Naltrexone 50mg (Whanin Naltrexone Tab. 50mg)
- Where
- 3 sites in South Korea
- Volunteers
- 150 people
- Sponsor
- Seoul National University Hospital
Violence
School Based Program to Prevent Teen Dating Violence
This study is a school-based trial of the 7th grade version of Fourth R, a promising teen dating violence prevention program, with 24 ethnically diverse middle schools in one of the nation's largest school districts to determine…
- Trial name
- CRT (NCT02909673)
- Testing
- Fourth R
- Where
- 2 sites in United States
- Volunteers
- 3,028 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Disability, Adolescent Learning, Psychosocial Problem
Effects of a Laughter Yoga Program in Adolescents With Disabilities
A pilot randomized controlled trial will be adopted. A total of forty adolescents with intellectual and physical disabilities will be randomly allocated into either intervention group receiving a 4-week laughter yoga programme (8…
- Trial name
- NCT05832346
- Testing
- Laughter yoga programme
- Where
- Hong Kong
- Volunteers
- 45 people
- Sponsor
- Chinese University of Hong Kong
HIV
Assisting HIV-infected Mothers in Disclosing Their Serostatus to Their Children
This study will develop and evaluate the effectiveness of an intervention designed to assist HIV-infected mothers of young children in determining whether and how to appropriately disclose their HIV serostatus to their children.
- Trial name
- TRACK (NCT00429546)
- Testing
- Teaching, Raising, and Communicating with Kids (TRACK), Treatment as usual
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- University of California, Los Angeles
Substance Use Disorders, Comorbidities and Coexisting Conditions
Adaptation of Community Reinforcement Approach for the Treatment of Drug Addiction
Central idea of the study is to adapt a treatment program for drug addiction treatment indigenously and relapse prevention, and to establish its efficacy.
- Trial name
- NCT06559631
- Testing
- Indigenously Adapted CRA
- Where
- 2 sites in Pakistan
- Volunteers
- 59 people
- Sponsor
- Muhammad Saghir
Parenting, Parent-Child Relations
Effect Evaluation of The International Child Development Programme (ICDP)
This study evaluate if a parental guidance programme based on the International Child Development Programme (ICDP) offered to the general Norwegian population, has an effect on caregivers, the relationship between caregiver and…
- Conditions
- Parenting, Parent-Child Relations, Child Development
- Trial name
- ICDP RCT (NCT03040895)
- Testing
- Group-based ICDP-intervention, Treatment as usual
- Where
- Norway
- Volunteers
- 666 people, healthy volunteers welcome
- Sponsor
- Norwegian Institute of Public Health
Shoulder Instability
Surgical Treatment of Recurrent Shoulder Dislocations
This is a pilot multi-centre, double blinded randomized controlled trial. The primary outcome of this pilot trial will be feasibility.
- Trial name
- NCT05564494
- Testing
- Bankart Repair, Anatomic Glenoid Reconstruction
- Where
- 2 sites in United States, Canada
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Nova Scotia Health Authority
Muscular Atrophy, Spinal
A Study of the Safety of Nusinersen (Spinraza®) and Its Effects on Motor Function in Koreans Living With SMA Treated During Their Usual Medical Care
In this study, researchers will learn more about the effects of nusinersen, also known as Spinraza®, in Korean participants with spinal muscular atrophy, also known as SMA.
- Trial name
- STANDARD (NCT04317794)
- Testing
- Nusinersen Sodium Injection
- Where
- 16 sites in South Korea
- Volunteers
- 74 people
- Sponsor
- Biogen
Obsessive-Compulsive Disorder
Mindfulness-Based Cognitive Therapy in a Clinical Sample of OCD Patients
Obsessive Compulsive Disorder (OCD) is a chronic and debilitating disorder known to have reported lifetime prevalence in the range of 2%.
- Trial name
- NCT02217995
- Testing
- Mindfulness-Based Cognitive Therapy (MBCT)
- Where
- Canada
- Volunteers
- 32 people
- Sponsor
- Sunnybrook Health Sciences Centre
Cerebral Palsy
Dynamic, Real-world Learning, Innovative Mobility, and Versatile Exploration (DRIVE): Evaluating a Dose-matched Developmental Powered Mobility Intervention for Young Children With Cerebral Palsy
The goal of this clinical trial is to understand the effects of developmental powered mobility intervention on global development, gross motor function, and activity performance outcomes in 48 young children (ages 1-2 years) with…
- Trial name
- DRIVE (NCT07876219)
- Testing
- Permobil Explorer Mini, MORE-PT
- Where
- 2 sites in United States
- Volunteers
- 48 people
- Sponsor
- University of Washington
Oppositional Defiant Disorder, Conduct Disorder
Resources to Enhance the Adjustment of Children (REACH)
This continuation study evaluates the long-term outcomes of multimodal, modular interventions with early-onset behavior disordered children and innovative methods to promote the maintenance and extension of treatment effects…
- Conditions
- Oppositional Defiant Disorder, Conduct Disorder, Attention Deficit Hyperactivity Disorder
- Trial name
- REACH (NCT00820001)
- Testing
- Booster Treatment, No-Booster, No intervention
- Where
- 2 sites in United States
- Volunteers
- 254 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Hypertension
Skills-Based Educational Strategies for Reduction of Vascular Events in Orange County
The Skills-Based Educational strategies for Reduction of Vascular Events in Orange County, CA (SERVE OC) study aims to evaluate the efficacy of a culturally tailored, skills-based, cardiovascular health (CVH) intervention amongst…
- Trial name
- SERVEOC (NCT05641519)
- Testing
- SERVE OC Intervention, Enhanced Standard Intervention
- Where
- United States
- Volunteers
- 483 people
- Sponsor
- University of California, Irvine
Adolescent Depression
A Hybrid Psychological Intervention for Depression in Adolescents
This multi-center, randomized controlled trial was conducted to evaluate the efficacy and long-term effects of a novel hybrid psychological intervention, which combines Resilience Theory with the Satir Model, for adolescents…
- Trial name
- NCT07104851
- Testing
- Resilience-Satir Hybrid Intervention, Treatment as Usual (TAU)
- Where
- China
- Volunteers
- 420 people
- Sponsor
- The First Hospital of Hebei Medical University
Alcoholism
Trial Testing the Effect of Strategies on Performance of Brief Intervention Programmes for Harmful Alcohol Consumption
The overall objective is to study if training and support, financial reimbursement and referral to an internet based brief intervention programme, singly or in combination, may increase implementation of evidence based methods of…
- Trial name
- ODHIN_RCT (NCT01501552)
- Testing
- Training and support (T&S), Financial incentive, E-SBI (online screening and brief intervention)
- Where
- 10 sites in Netherlands, Poland and 3 more
- Volunteers
- 120 people
- Sponsor
- Fundacion Clinic per a la Recerca Biomédica
Verbal Auditory Hallucination, Psychotic Disorders
RELATE - Efficacy and Feasibility of a Cognitive Behavioural Module for Distressing Auditory Verbal Hallucinations
Auditory hallucinations (AH) are associated with distress and reduced functioning. Psychological interventions show some promising effects on psychopathology but have been less successful in reducing AH related distress, which…
- Conditions
- Verbal Auditory Hallucination, Psychotic Disorders, Psychosis, Schizophrenia
- Trial name
- RELATE (NCT04578314)
- Testing
- Relating Therapy, Treatment as usual
- Where
- 5 sites in Germany
- Volunteers
- 85 people
- Sponsor
- University of Hamburg-Eppendorf
Anesthesia, Depth of Hypnosis Monitoring
The Effect of DSA on Recovery of Anaesthesia in Children
In this randomised, blinded study, we will investigate the influence of DSA on recovery from general anaesthesia. DSA monitoring provides continuous information on depth of hypnosis.
- Trial name
- DSA-RCT-1 (NCT05525104)
- Testing
- Narcotrend Monitor (MT MonitorTechnik, Hannover, Germany)
- Where
- Netherlands
- Volunteers
- 112 people
- Sponsor
- Erasmus Medical Center
Oral Disease, Gingival Diseases
Effectiveness of MySmile App for Improving the Oral Health of Secondary School Children:
The goal of this cluster-randomised control trial is to assess the effectiveness of the MySmile app for improving oral health in secondary school children. The main questions it aims to answer are: 1.
- Trial name
- NCT06381700
- Testing
- MySmile app, Control
- Where
- Malaysia
- Volunteers
- 303 people, healthy volunteers welcome
- Sponsor
- University of Malaya
Obesity, Dyslipidemia
Use of Nutrigenomic Models for the Personalized Treatment With Medical Foods in Obese People
The NutriGen project will be using nutrigenomic methods to determine the effectiveness of treatments with specific dietary foods, on the basis of genetic risk predisposition (genetic signature) of obese individuals.
- Trial name
- NutriGen (NCT02837367)
- Testing
- Administration of supplements containing methyl-donors
- Where
- 2 sites in Romania
- Volunteers
- 600 people
- Sponsor
- University of Medicine and Pharmacy "Victor Babes" Timisoara
Infection
Far-UVC and Infections in Long-term Care Facilities
Background Elderly residents in long-term care (LTC) facilities are highly susceptible to infections, often leading to hospitalizations and placing significant strain on the healthcare sector.
- Trial name
- NCT07511881
- Testing
- Far-uvc (222 nm), Standard Care (Treatment as Usual)
- Where
- Denmark
- Volunteers
- 635 people, healthy volunteers welcome
- Sponsor
- Vejle Hospital
Mental Disorders, Substance-Related Disorders
Integrated Prevention and Collaborative Care for Youth Mental Health
Mental health problems affect 10-20% of children and adolescents worldwide, with half of affected youth experiencing problems by the age of 14.
- Conditions
- Mental Disorders, Substance-Related Disorders, Quality of Life
- Trial name
- NCT03114007
- Testing
- Preventure program, Equipe program, Inter-Action services
- Where
- Canada
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- St. Justine's Hospital
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