Clinical trials: Vitrectomy
Diabetes, Diabetes Mellitus
Thrombospondin-1 and Pigmented Epithelium Derived Factor Levels in Patients With Diabetes Mellitus.
You are being asked to be in a research study to determine blood levels and vitreous levels of compounds called thrombospondin 1 (TSP1) and pigment epithelium derived factor (PEDF). These compounds exists naturally in your body.
- Trial name
- PEDF (NCT01809093)
- Testing
- Blood draw
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- MidAtlantic Retina
Proliferative Diabetic Retinopathy, Vitrectomy
Observation of the Efficacy of Different Vitrectomy Systems to Treat Proliferative Diabetic Retinopathy
In recent years, vitrectomy has moved toward a minimally invasive vitrectomy surgery (MIV) system, which could effectively reduce the occurrence of operation complications, while reducing the time of post-operation recovery.
- Trial name
- NCT05446948
- Testing
- beveled 27G+ vitrectomy system, standard 25G+ vitrectomy system
- Where
- China
- Volunteers
- 52 people
- Sponsor
- Tianjin Medical University Eye Hospital
Retinopathy of Prematurity Both Eyes, Retinal Disease
Safety and Efficacy of 18 mm Short Vitrectomy Probe for Pediatric Vitreoretinal Surgeries
This study aims to study the safety and efficacy of using an 18 mm short vitrectomy probe for pediatric vitreoretinal surgeries and to investigate the surgeon's comfort and reliability of using the shorter probe.
- Conditions
- Retinopathy of Prematurity Both Eyes, Retinal Disease, Persistent Fetal Vasculature, Coats Disease
- Trial name
- NCT06520410
- Testing
- Pars plana vitrectomy with a 18 mm short vitrector
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Chang Gung Memorial Hospital
Corneal Epithelial Defects After Ocular Surgeries
Topical Autologous Insulin Application for the Treatment of Corneal Epithelium Defect After Ocular Surgeries
Topical insulin application has been proved recently to increase corneal reepithelization rate over diabetic animals. However, its effectiveness on corneal epithelial wound healing in patients who received pars planar vitrectomy…
- Trial name
- NCT01031888
- Testing
- Topical insulin eye drops, Conventional postoperative eye drops
- Where
- Taiwan
- Volunteers
- 18 people
- Sponsor
- National Taiwan University Hospital
Pediatric Rhegmatogenous Retinal Detachment
Outcomes of Vitrectomy in Pediatric Retinal Detachment With Proliferative Vitreoretinopathy
The aim of this study is to report outcomes of pars plana vitrectomy (PPV) in pediatric retinal detachment (RD) accompanied with proliferative vitreoretinopathy (PVR) as well as complications and factors influencing the final…
- Trial name
- NCT03208205
- Testing
- vitrectomy
- Where
- Poland
- Volunteers
- 14 people
- Sponsor
- Medical University of Lublin
Glaucoma Secondary
Treatment of Malignant Glaucoma by Anterior Vitrectomy From Two Different Approaches
To compare the surgical outcomes of treating phacoemulsification with intraocular lens implantation combined with goniosynechialysis (Phaco-IOL-GSL) associated malignant glaucoma (MG), using different incision sites in anterior…
- Trial name
- NCT04172857
- Testing
- anterior vitrectomy combined with hyaloidotomy, zonulectomy and iridectomy
- Volunteers
- 9 people
- Sponsor
- Wenzhou Medical University
Diabetic Retinopathy
Effect of Intravitreal Bevacizumab on Early Post-Vitrectomy Hemorrhage in Diabetic Patients
The purpose of this study is to determine whether bevacizumab 1-2 weeks before vitrectomy is effective in lowering the rate of early post-vitrectomy vitreous hemorrhage in diabetic patients.
- Trial name
- NCT00524875
- Testing
- Bevacizumab
- Where
- Iran
- Volunteers
- 80 people
- Sponsor
- Shahid Beheshti University of Medical Sciences
Optic Disc Pit Maculopathy
Vitrectomy for Optic Disc Pit Maculopathy
The purpose of this study is to evaluate the efficacy of vitrectomy, without gas tamponade or laser photocoagulation to the margin of the optic nerve, for the treatment of macular detachment associated with optic disc pits and to…
- Trial name
- NCT01340703
- Testing
- vitrectomy without laser or gas tamponade
- Where
- Japan
- Volunteers
- 8 people
- Sponsor
- Kyorin University
Endophthalmitis, Eye Infections
Endophthalmitis Vitrectomy Study (EVS)
To determine the role of initial pars plana vitrectomy in the management of postoperative bacterial endophthalmitis. To determine the role of intravenous antibiotics in the management of bacterial endophthalmitis.
- Trial name
- NCT00000130
- Testing
- Intravitreal Antibiotics, Initial Pars Plana Vitrectomy
- Sponsor
- National Eye Institute (NEI)
Retinal Detachment, Macular Hole
Head Position Monitoring After Pars Planar Vitrectomy
In ophthalmic surgical practice, particularly for treating retinal detachment and macular hole disorders, vitrectomy procedures are routinely performed to remove the vitreous body followed by the injection of tamponade agents…
- Trial name
- HPMPPV (NCT06985030)
- Testing
- gyroscope embedded eye-sheild
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Seoul National University Hospital
Cataract, Epiretinal Membrane
Combined 25-gauge Vitrectomy and Cataract Surgery With Toric Intraocular Lens With Idiopathic Epiretinal Membrane.
Toric intraocular lens (IOL) is now widely used for the cataract surgery with preoperative corneal astigmatism. Symptomatic epiretinal membrane (ERM) is often treated with 25-gauge transconjunctival sutureless vitrectomy…
- Conditions
- Cataract, Epiretinal Membrane, Corneal Astigmatism
- Trial name
- NCT02328157
- Testing
- Vitrectomy with cataract surgery and toric IOL, Vitrectomy with cataract surgery and common IOL
- Where
- Japan
- Volunteers
- 30 people
- Sponsor
- Kagawa University
Suprachoroidal Hemorrhage (Diagnosis), Pars Plana Vitrectomy
Suprachoroidal Hemorrhage Associated With Pars Plana Vitrectomy
To analyze the characteristics, related risk factors, and prognosis of suprachoroidal hemorrhage (SCH) associated with pars plana vitrectomy (PPV).
- Trial name
- NCT05013281
- Testing
- Suprachoroidal hemorrhage associated with pars plana vitrectomy
- Where
- China
- Volunteers
- 28 people
- Sponsor
- Beijing Tongren Hospital
Optic Disc Structural Anomaly, Maculopathy
Surgical Management of Optic Disc Pit Maculaopathy
To evaluate the anatomical and functional results of pars plana vitrectomy (PPV) combined with internal limiting membrane (ILM) peeling, endolaser photocoagulation and gas tamponade in management of optic disc pit (ODP)…
- Trial name
- NCT03185936
- Testing
- pars plana vitrectomy with internal limiting membrane (ILM) peeling
- Volunteers
- 9 people
- Sponsor
- Minia University
Diabetes Mellitus, Diabetic Retinopathy
Intravitreal Long Acting Gas in the Prevention of Early Postoperative Vitreous Hemorrhage in Diabetic Vitrectomy
Recurrent vitreous hemorrhage after vitrectomy for complications of diabetic retinopathy is a common occurrence. The hemorrhage may appear within the first few weeks after surgery or months later.
- Conditions
- Diabetes Mellitus, Diabetic Retinopathy, Vitreous Hemorrhage
- Trial name
- NCT00155454
- Testing
- Intravitreal long acting gas (10% C3F8)
- Where
- Taiwan
- Volunteers
- 61 people
- Sponsor
- National Taiwan University Hospital
Proliferative Diabetic Retinopathy
Compliance to Ophthalmic Follow-up Examinations and Surgical Outcome for Proliferative Diabetic Retinopathy
The relationship between the surgical outcome of vitreous surgery for proliferative diabetic retinopathy and the compliance to ophthalmic follow-up examinations was evaluated.
- Trial name
- NCT01307072
- Testing
- Vitrectomy
- Where
- Japan
- Volunteers
- 94 people
- Sponsor
- Kyorin University
Malignant Glaucoma
Zonulo-hyaloido-vitrectomy for Malignant Glaucoma
The purpose of this study is to assess the zonulo-hyaloido-vitrectomy for malignant glaucoma through an anterior approach.
- Trial name
- NCT02613143
- Where
- China
- Volunteers
- 10 people
- Sponsor
- Wenzhou Medical University
Ophthalmopathy
Autologous Blood for Full-thickness Macular Hole
Autologous blood for primary and recurrent holes
- Trial name
- NCT05494229
- Testing
- Pars-plana vitrectomy
- Where
- Iraq
- Volunteers
- 5 people
- Sponsor
- Omer Othman Abdullah
Proliferative Diabetic Retinopathy
Efficacy of PreOperative Bevacizumab for Diabetic Eye Disease
Reports of the use of intravitreal bevacizumab (Avastin, Genentech) for the reduction of neovascularization in proliferative diabetic retinopathy have demonstrated significant regression in the number of new vessels.
- Trial name
- NCT01041690
- Testing
- Bevacizumab
- Where
- Egypt
- Volunteers
- 19 people
- Sponsor
- Cairo University
Retinal Disease
Modified Soft Contact Lens During Vitrectomy
This study compared a modified soft contact lens with balanced salt solution irrigation during pars plana vitrectomy performed with a noncontact wide-angle viewing system.
- Trial name
- NCT07807436
- Testing
- Modified Soft Contact Lens, Balanced Salt Solution Irrigation
- Where
- China
- Volunteers
- 46 people
- Sponsor
- Northwest University First Hospital (Xi'an No.1 Hospital)
Retinal Detachment
Scleral Self-indentation Chandelier-assisted Peripheral Vitrectomy Under Air Rhegmatogenous Retinal Detachment.
The investigators compared the incidence of trimming-induced retinal breaks, retinal redetachment rate, and final LogMAR BCVA; between scleral self-indentation and non-indentation during chandelier-assisted peripheral vitrectomy…
- Trial name
- NCT03218371
- Testing
- chandelier-assisted peripheral vitrectomy under air
- Where
- Egypt
- Volunteers
- 130 people
- Sponsor
- Dar El Oyoun Hospital