Clinical trials: Urethroplasty
Hypospadias
Local Oestrogen Versus Placebo as Preoperative Treatment in Patients With Severe Hypospadias: Effects on Post-operative Complications
Hypospadias is a congenital abnormality of the penis that is caused by incomplete development of the anterior urethra. This pathology is one of the most common genital anomalies in paediatric urology .The incidence is reported to…
- Trial name
- HYPOSPADES (NCT01370798)
- Testing
- promestriene, Urethroplasty, Wrist X ray
- Where
- 4 sites in France
- Volunteers
- 244 people
- Sponsor
- Hospices Civils de Lyon
Proximal Hypospadias, Modified Duckett Urethroplasty
Hybrid Duckett vs Modified Duckett Urethroplasty for Proximal Hypospadias
proximal hypospadias presents a serious anomaly for both infants and their care givers. a variety of techniques were described through decades. None of them is completely curable.
- Trial name
- NCT06598215
- Testing
- Duckett urethroplasty
- Where
- Egypt
- Volunteers
- 43 people
- Sponsor
- Tanta University
Urethrocutaneous Fistulas
2-octyl Cyanoacrylate for Closure of Urethrocutaneous Fistula.
Urethrocutaneous fistulae (UCF) represent one of the most frequent causes of morbidity after urethroplasty. Hypospadias can be repaired using different surgical techniques, but regardless of technique, the incidence of UCF ranges…
- Trial name
- NCT02115191
- Testing
- 2-octylcyanoacrylate, Surgical reintervention
- Where
- Mexico
- Volunteers
- 42 people
- Sponsor
- Instituto Mexicano del Seguro Social
Distal Hypospadias, Hypospadias
Fibrin-Enhanced TIP Versus Grafted TIP Urethroplasty in Distal Hypospadias
Hypospadias is a common congenital condition in boys in which the opening of the urethra is located on the underside of the penis.
- Trial name
- FTIP-RCT (NCT07319780)
- Testing
- Fibrin-Enhanced TIP Urethroplasty, Grafted TIP Urethroplasty
- Where
- 2 sites in Indonesia, Uzbekistan
- Volunteers
- 100 people
- Sponsor
- National Children's Medical Center, Uzbekistan
Urethral Stricture
Factors Predicting Urethral Stricture Recurrence After Dorsal Onlay Augmented, Buccal Mucosal Graft Urethroplasty
In this observational study, the investigators will evaluate potential risk factors associated with urethral stricture recurrence after augmentation anterior urethroplasty using dorsal onlay buccal mucosal Graft during the past…
- Trial name
- NCT04357080
- Testing
- Urethroplasty
- Where
- Egypt
- Volunteers
- 266 people
- Sponsor
- Al-Azhar University
Failed Anastomotic Urethroplasty
Radiological Re-evaluation of Failed Anastomotic Uretheroplasty for PFUDDI Using Computed Tomographic Urethrography.
Estate vlue of CTU in evaluation of failed anastomotic urethroplasty for pelvic fracture urethral distraction defect injury [PFUDDI] combared to retrograde urethrography and voiding cysto-urethrography .
- Trial name
- NCT03328000
- Testing
- CTU and MR urethrography
- Volunteers
- 20 people
- Sponsor
- Assiut University
Urethral Stricture, Male
Comparison Between Two Techniques Used in Treatment of Long Anterior Urethral Stricture
To evaluate dorsolateral and dorsal approach urethroplasty in treatment of anterior urethral stricture by using buccal mucosal graft as regard voiding and sexual outcomes.
- Trial name
- NCT05918315
- Testing
- Buccal mucosa substitution urethroplasty
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Sohag University
Hypospadias, Distal Penile Hypospadias (Disorder)
Effect of Adding Byar's Flap to Double Dartos Coverage in TIP Urethroplasty for Distal Hypospadias: A Randomized Trial
This randomized controlled trial evaluates the effect of adding Byar's flap in combination with double dartos flap coverage during tubularized incised plate (TIP) urethroplasty in children with distal hypospadias.
- Trial name
- DD-TIP-BF (NCT07525570)
- Testing
- Double Dartos Flap Coverage, Byar's Flap + Double Dartos Flap
- Where
- Pakistan
- Volunteers
- 120 people
- Sponsor
- Javaid Afridi
Hypospadias
Urethrocutaneous Fistula Rate After Double Dartos and Single Dartos Tubularized Incised Plate Urethroplasty
The subjects were divided into two groups. Each group comprised 30 children. Children were randomly allocated in two groups via computer generated tables.
- Trial name
- NCT04699318
- Testing
- Group B, Group A
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- King Edward Medical University
Distal Penile Hypospadias (Disorder)
Hybrid Mathieu Urethroplasty
the aim is to study the results of simple modification of classic Mathieu urethroplasty to increase the scope of cases candidates for that procedure.
- Trial name
- NCT04946058
- Testing
- hyebrid Mathieu Urethroplasty
- Volunteers
- 43 people
- Sponsor
- Tanta University
Hypospadias
Randomized Trial Of Urethroplasty With Stent Versus Without Stent For Hypospadias
Hypospadias is a birth condition in which the urine opening is on the underside of the penis. Surgery (urethroplasty) is the standard treatment.
- Trial name
- UCFStentRCT (NCT07243457)
- Testing
- Stent urethroplasty, Stentless urethroplasty
- Where
- Pakistan
- Volunteers
- 110 people
- Sponsor
- Children's Hospital and Institute of Child Health, Multan
Penile Skin, Buccal Mucosal Graft
Penile Skin Versus Buccal Mucosal Graft in Augmentation Urethroplasty for Long Anterior Urethral Stricture
The aim of this study is to analyze the outcomes of dorsal onlay buccal mucosal graft (BMG) and penile skin graft (PSG) urethroplasty in the management of long segment bulbar urethral stricture.
- Conditions
- Penile Skin, Buccal Mucosal Graft, Augmentation, Urethroplasty
- Trial name
- NCT07074717
- Testing
- Buccal Mucosal Graft (BMG) Urethroplasty, Penile Skin Graft (PSG) Urethroplasty
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Tanta University
Hypospadias, Complication,Postoperative
Evaluation of TIP Urethroplasty With Spongioplasty-Dartosoraphy Reinforcement in Pediatric Hypospadias
The study aimed to evaluation of Tubularized incised palate urethroplasty with spongioplasty-dartosoraphy reinforcement (group A) through comparing of functional and cosmetic results of this technique with the conventional TIP…
- Trial name
- NCT05960123
- Testing
- Tubularized Incised Plate (TIP) urethroplasty
- Where
- Egypt
- Volunteers
- 220 people
- Sponsor
- Al-Azhar University
Re-operative, Hypospadias
Re-operative Hypospadias Repair Using Tubularized Incised Plate Urethroplasty
The aim of this study is to evaluate the outcomes, feasibility, and complication profile of re-operative hypospadias repair using tubularized incised plate urethroplasty as a single-stage procedure in a single-center experience.
- Conditions
- Re-operative, Hypospadias, Tubularized Incised Plate, Urethroplasty
- Trial name
- NCT07424768
- Testing
- Tubularized Incised Plate Urethroplasty
- Where
- Egypt
- Volunteers
- 15 people
- Sponsor
- Tanta University
Hypospadias
Foreskin Graft Tubularized Incised Plate Urethroplasty vs Tubularized Incised Plate for Primary Hypospadias (FGTIP-TIP)
The purpose of this study is to determine the efficacy and safety of tubularized incised plate urethroplasty versus foreskin graft tubularized incised plate urethroplasty in primary hypospadias.
- Trial name
- FGTIP-TIP (NCT02497963)
- Testing
- Foreskin Graft-Tubularized Incised Plate, Tubularized Incised Plate
- Volunteers
- 68 people
- Sponsor
- Hospital Infantil de Mexico Federico Gomez
Urethral Stricture
9000 URETHRA STUDY: a Study About Urethroplasty for Urethral Stricture Disease
It has been demonstrated that urethroplasty should be considered the gold standard treatment for urethral stricture disease as it yields higher long-term success rates than endoscopic treatment options such as direct vision…
- Trial name
- NCT04071925
- Testing
- Urethroplasty
- Where
- 2 sites in Belgium
- Volunteers
- 1,000 people
- Sponsor
- University Hospital, Ghent
Narrow Urethral Plate Hypospadias
Evaluation of Slit-like Adjusted Mathieu Versus Onlay Island Flap for Hypospadias Repair in Pediatrics
Purpose** To compare the Slit-like Adjusted Mathieu (SLAM) technique versus the inner transverse preputial onlay island flap for repair of anterior and mid-penile hypospadias with narrow urethral plate, evaluating complication…
- Trial name
- NCT07592026
- Testing
- Slit-like Adjusted Mathieu, onlay island flap
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Al-Azhar University
Completed
Preputial Graft Urethroplasty in Primary Repair of Hypospadias
Introduction: Hypospadias repair is debated. There has been no perfect procedure until this moment. A graft is sometimes needed to fundamentally strengthen the narrow urethral plate.
- Trial name
- Hypospadias (NCT05660564)
- Testing
- DIGU Dorsal inlay preputial graft urethroplasty
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Sarah Magdy Abdelmohsen
Urethral Stricture
Urethral Stricture: A Comparison Between Jugal or Labial Graft Urethroplasty
Buccal mucosa urethroplasty is a current fashion in urethral stricture management. In our university centre (Hospital de Clínicas de Porto Alegre) is a common surgical treatment choice.
- Trial name
- NCT03973619
- Testing
- Labial Graft, Jugal Graft
- Volunteers
- 77 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Hypospadias, Penoscrotal, Chordee
Transverse Preputial Island Flap Versus Double Faced Preputial Flap for Repair of Penoscrotal Hypospadias With Chordee
The purpose of this study is to compare the outcomes and complications of the transverse preputial island flap (Duckett's procedure) to those of double-faced preputial flap (DFPF) for one-stage repair of penoscrotal hypospadias…
- Trial name
- DuckettvDFPF (NCT04605068)
- Testing
- Transverse preputial island flap (Duckett's technique), Double-faced preputial flap (DFPF)
- Volunteers
- 144 people
- Sponsor
- dr. Muhammad Abdelhafez Mahmoud, MD