Clinical trials: Type1diabetes
Type1diabetes
Evaluation of a Decision Support System for People With Diabetes Who Use Multiple Daily Insulin Injections- Feasibility and Proof of Concept Studies
The study comprises of two segments: a feasibility segment and a Proof of Concept segment. The study is open label, prospective study that will include up to 72 subjects in segment 1 and up to 40 subjects in segment 2.
- Trial name
- NCT04653961
- Testing
- DreaMed Advisor Pro DSS-MDI algorithm
- Where
- 2 sites in Israel
- Volunteers
- 48 people
- Sponsor
- Rabin Medical Center
Type1diabetes, Adolescent Behavior
Sleep, Glycemic Control, and Insulin Resistance in Adolescents With Type 1 Diabetes
Despite advancements in care, most adolescents with T1D have higher BMI and significantly higher HbA1c than recommended and are markedly IR, placing them at increased risk for CVD1,2.
- Conditions
- Type1diabetes, Adolescent Behavior, Sleep
- Trial name
- SunDIAL (NCT03832790)
- Testing
- observation
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- University of Colorado, Denver
Celiac Disease in Children, Autoimmune Diseases
Gluten Reduction and Risk of Celiac Disease
Celiac disease shares many features of other autoimmune diseases such as type 1 diabetes. Recently, it was published that higher amounts of gluten intake increased the risk for celiac disease.
- Conditions
- Celiac Disease in Children, Autoimmune Diseases, type1diabetes
- Trial name
- GRAIN (NCT04593888)
- Testing
- Gluten reduced diet
- Where
- Sweden
- Volunteers
- 1,141 people
- Sponsor
- Lund University
Type1diabetes
Family-Based Behavioral Medical Nutrition Therapy Education in Children and Adolescents With Type 1 Diabetes
Type 1 Diabetes Mellitus (T1DM) is a heterogeneous condition and is an absolute insulin deficiency resulting from autoimmune-mediated destruction of pancreatic β-cells (1).
- Trial name
- NCT05411952
- Testing
- Medical nutrition therapy and carbohydrate counting education, No intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people
- Sponsor
- Hasan Kalyoncu University
type1diabetes
Remote Digital Care Effects in Adolescents With Type 1 Diabetes
Pilot study to evaluate effects of an experimental additional remote digital care (TELEDUC-DIAB) to adolescents with poorly controlled type 1 diabetes using digital monitoring platform and educative app
- Trial name
- TELEDUC-DIAB1 (NCT05421715)
- Testing
- TELEDUC-DIAB
- Where
- France
- Volunteers
- 10 people
- Sponsor
- University Hospital, Toulouse
Type1diabetes, Diabetes
China Diabetes Type 1 Study (CD1S) by China Alliance for Type 1 Diabetes
The aim of the China Diabetes Type 1 Study (CD1S) is to conduct a nationwide type 1 diabetes (T1D) registry study in patients with T1D and in pediatric adolescent patients with diabetes who had an age of onset <= 20 years.
- Trial name
- NCT05498974
- Testing
- Standard type 1 diabetes management model constructed by China Alliance for Type 1 Diabetes in each center
- Where
- 11 sites in China
- Volunteers
- 20,000 people
- Sponsor
- Second Xiangya Hospital of Central South University
Type1diabetes, Childhood ALL
Hb A1C Pre and Post Confinement in Latin American Children With Type 1 Diabetes: Dulce Study Group
A multicenter retrospective observational study among children with type 1 diabetes will be performed. The Objective of this study will be to determine a) the association between the increase in Hba1c in children with type 1…
- Trial name
- NCT04640064
- Where
- Argentina
- Volunteers
- 500 people
- Sponsor
- Hospital General Puyo
Diabetes Mellitus, Type1diabetes
The Effect of Human Milk Oligosaccharides in Children With Type 1 Diabetes Mellitus
Type 1 diabetes mellitus (DM) is an autoimmune disease characterized by absolute insulin deficiency, defined as insulin-dependent diabetes mellitus and develops due to autoimmune damage of beta cells in the pancreas.
- Trial name
- NCT05521061
- Testing
- 2-fucosyllactose
- Where
- Turkey (Türkiye)
- Volunteers
- 111 people
- Sponsor
- Ege University
Type1diabetes
Assessment of Two Insulin Pump Insulin Delivery Systems in Type 1 Diabetes.
This is a study of the Minimed 670G 4.0 insulin pump, assessing the efficacy of the Advanced Hybrid Closed Loop (AHCL) algorithm in controlling blood glucose levels in Type 1 Diabetes.
- Trial name
- NCT04073576
- Testing
- AHCL, SAP+PLGM
- Where
- New Zealand
- Volunteers
- 60 people
- Sponsor
- Christchurch Clinical Studies Trust Ltd
Type1diabetes
Skeletal Fragility in Type 1 Diabetes: Glycemic Control and Bone Strength
The purpose of this research study is to find out how bones are affected in children and adolescents with type 1 diabetes (T1D) as compared to children and adolescents without type 1 diabetes.
- Trial name
- NCT04289727
- Where
- United States
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Columbia University
Type 1 Diabetes Mellitus With Hypoglycemia, type1diabetes
Intermediate and Long Acting Insulin Young Children Type 1 Diabetes.
Background: Achieving glycemic control without risking hypoglycemia imposes a major challenge in the management of toddlers and preschool children with Type 1 diabetes(T1D).
- Trial name
- NCT04664764
- Testing
- Degludec, Glargine, NPH insulin
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
type1diabetes
The Breakfast Rise, Education and Knowledge Study
The study proposes to recruit 90 children and young people who have type 1 diabetes (T1D) and who regularly use Dexcom continuous glucose monitoring (CGM).
- Trial name
- BREAK (NCT05698875)
- Testing
- Breakfast meals
- Where
- United Kingdom
- Volunteers
- 48 people
- Sponsor
- University of Stirling
Type1diabetes
Bridging the Gap to Adult Diabetes Care
Adolescents with type 1 diabetes face particular challenges related to having a chronic illness that requires daily intensive self-management and medical follow-up during a period when their social, developmental, educational…
- Trial name
- NCT03781973
- Testing
- Data platform +Quality Performance feedback reports
- Where
- 5 sites in Canada
- Volunteers
- 484 people
- Sponsor
- The Hospital for Sick Children
Type1diabetes
Automated Insulin Delivery vs. Injections: Sleep Impact in Pediatric Type 1 Diabetes
The purpose of the study is to learn about the effect of insulin pumps on sleep in pediatric patients with type 1 diabetes and their caregivers.
- Trial name
- NCT06347783
- Testing
- Insulin pump
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Oregon Health and Science University
type1diabetes
Feasibility Trial of a Mindfulness Based Intervention in Youth With Type 1 Diabetes
Type 1 diabetes (T1D) is one of the most common chronic illnesses of childhood. The involved treatment regimen, including daily insulin administration/pump management, frequent blood glucose checks, and careful track-ing of food…
- Trial name
- BREATHE-T1D (NCT05268393)
- Testing
- BREATHE-T1D
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Children's National Research Institute
Type1diabetes, Celiac Disease
Newborn Screening for Genetic Susceptibility to Type 1 Diabetes and Celiac Disease and Prospective Follow-up Study
This is an observational study, in which newborn infants from the general population are screened at birth for HLA-conferred susceptibility to type 1 diabetes and celiac disease.
- Trial name
- BABYSCREEN (NCT04958356)
- Where
- Finland
- Volunteers
- 9,690 people, healthy volunteers welcome
- Sponsor
- University of Helsinki
Type1diabetes, Fasting Hypoglycemia
Sahoor Meal Regimen for Patients With Type1 Diabetes
To examine effects of two approaches to sahoor meal consumption during Ramadan on blood sugar control and incidence of early day hypoglycemic episodes requring the discontinuation of fasting.
- Trial name
- NCT04864483
- Testing
- Meal timing in relation to time of starting the fast
- Where
- Saudi Arabia
- Volunteers
- 44 people
- Sponsor
- King Abdullah International Medical Research Center
Type 1 Diabetes, Type1diabetes
Probiotics in Newly Diagnosed T1D
The investigators aim to further the understanding of environmental factors that underlie the development of Type 1 diabetes (T1D) and the post-onset disease trajectory.
- Conditions
- Type 1 Diabetes, Type1diabetes, Type 1 Diabetes Mellitus
- Trial name
- NCT04141761
- Testing
- Visbiome
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- Medical College of Wisconsin
Type1diabetes, Type1 Diabetes Mellitus
Modulation of Type 1 Diabetes Susceptibility Through the Use of Probiotics
Investigators aim to further the understanding of environmental factors that underlie the progression to Type 1 diabetes (T1D). Dysbiosis, defined as alterations in intestinal microbiota composition and function, has been…
- Trial name
- NCT03423589
- Testing
- VSL#3
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Medical College of Wisconsin
Type1diabetes, Hypoglycemia
Introducing CGM at Type 1 Diabetes Diagnosis
Diabetes technology is changing and has quickly become an integral part of diabetes care and management. The study team plans to study the effects of introducing technology to newly diagnosed type 1 diabetes patients.
- Trial name
- NCT03736083
- Testing
- Freestyle Libre Blood Glucose Monitor
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Florida