Clinical trials: Trauma Blunt
Thoracic Aorta, Thoracic Injuries
TRANSFIX Zenith® Transection Clinical Study
The TRANSFIX study is a clinical trial approved by US FDA to study the safety and effectiveness of the Zenith® TX2® Low Profile Endovascular Graft for treatment of Blunt Thoracic Aortic Injury.
- Conditions
- Thoracic Aorta, Thoracic Injuries, Blunt Injuries
- Trial name
- TRANSFIX (NCT01688050)
- Testing
- Zenith® TX2® Low Profile Endovascular Graft
- Where
- 21 sites in United States
- Volunteers
- 50 people
- Sponsor
- Cook Research Incorporated
Blunt Chest Trauma
The Effect of Virtual Reality on Pulmonary Recovery and Mobility in Patients With Blunt Chest Trauma
Blunt chest trauma comprises over 10% of all trauma patients presenting to emergency departments worldwide and is the most frequent injury in polytrauma patients.
- Trial name
- VIREX PURE (NCT05194176)
- Testing
- Virtual Reality
- Where
- Netherlands
- Volunteers
- 27 people
- Sponsor
- Radboud University Medical Center
Liver Injury
Non-Operative Management of High Grade Blunt Hepatic Injury: Clinical Complications and the Role of Collateral Damage
Little is known about the role of collateral damage in patients with high grade liver injuries (LI). This retrospective single centre study investigates the safety of the non-operative management of patients with high grade blunt…
- Trial name
- NOMLI (NCT00694499)
- Where
- Switzerland
- Volunteers
- 183 people
- Sponsor
- University of Bern
Acute Blunt Soft Tissue Injuries/Contusions
Efficacy and Safety of Diclofenac Sodium Topical Gel 1% Compared to Placebo in Subjects With Acute Blunt Trauma Injuries
This study will assess the analgesic efficacy of DSG 1% compared to placebo in the reduction of the pain associated with acute blunt trauma injuries.
- Trial name
- NCT02290821
- Where
- 10 sites in United States
- Volunteers
- 215 people
- Sponsor
- Novartis
Lactate Blood Increase, Trauma Blunt
Lactate Monitoring in Traumatic Long Bone Fractures Requiring Emergent Surgical Intervention
Serum lactate has been utilized as a standard in guiding management of orthopedic injuries. Elevated preoperative lactate has been associated with a higher likelihood of postoperative complications.
- Conditions
- Lactate Blood Increase, Trauma Blunt, Trauma, Secondary, Injury Traumatic
- Trial name
- NCT05611398
- Testing
- Orthopedic Surgery
- Where
- United States
- Volunteers
- 164 people
- Sponsor
- Arrowhead Regional Medical Center
Traumatic Brain Injury
Traumatic Brain Injury - Knowledge Translation
Blunt head trauma (BHT) accounts for >450,000 emergency department (ED) visits for children annually in the US. Fortunately, >95% of head trauma in children is minor in nature.
- Trial name
- TBI-KT (NCT01453621)
- Testing
- Computerized clinical decision support
- Where
- United States
- Volunteers
- 28,669 people
- Sponsor
- Columbia University
Blunt Trauma, Penetrating Wound
Field Trial of Hypotensive Versus Standard Resuscitation for Hemorrhagic Shock After Trauma
Primary Aim: To determine the feasibility and safety of hypotensive resuscitation for the early treatment of patients with traumatic shock compared to standard fluid resuscitation.
- Conditions
- Blunt Trauma, Penetrating Wound, Hemorrhagic Shock
- Trial name
- HypoResus (NCT01411852)
- Testing
- 0.9% Sodium Chloride 250 mL bolus, 0.9% Sodium Chloride 2000 mL bolus
- Where
- 6 sites in United States, Canada
- Volunteers
- 192 people
- Sponsor
- University of Washington
Blunt Injury of Thorax
Abg in Blunt Chest Trauma
This study aims to determine the value of ABG measurments in patients with blunt chest trauma and its role in prognosis of different outcomes and the results would aid the emergency physicians to speed up the management and…
- Trial name
- NCT05886946
- Testing
- ABG
- Volunteers
- 150 people
- Sponsor
- Assiut University
Pneumothorax; Acute, Trauma Chest
Occult Pneumothorax in Patients With Blunt or Penetrating Trauma
Pneumothorax is a common life-threatening complication, frequently seen in patients who have been admitted to the emergency department and intensive care unit.
- Trial name
- NCT04188938
- Testing
- Evaluation of occult pneumothorax in who had a blunt or penetrating chest trauma
- Volunteers
- 105 people
- Sponsor
- European University of Lefke
Injuries and Wounds
the Role of Total Body Imaging in Asymptomatic Pediatric Trauma Patients
Whole body imaging has no role in asymptomatic pediatric trauma patients
- Trial name
- NCT00424736
- Testing
- whole body CT scan
- Volunteers
- 100 people
- Sponsor
- Assaf-Harofeh Medical Center
Head Injury, Traumatic Brain Injury
Selective CT for Anticoagulated Head Injured Patients
The goal is to derive and a clinical decision rule for safe exclusion of traumatic brain injury without neuroimaging in head-injured ED patients who take anticoagulant medications. The objectives are to: 1.
- Conditions
- Head Injury, Traumatic Brain Injury, Intracranial Hemorrhage, Traumatic, Blunt Head Injury
- Trial name
- Can-SCAHn (NCT05364749)
- Where
- 7 sites in Canada
- Volunteers
- 4,000 people
- Sponsor
- Dr. Kerstin de Wit
Renal Injury
Prospective Evaluation of Blunt Renal Injury in Children
The objective of this study is to evaluate the outcomes of children who have sustained blunt renal injury and to evaluate our current bed rest protocol.
- Trial name
- NCT00855036
- Testing
- Attenuated bedrest
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Children's Mercy Hospital Kansas City
Hemothorax, Pneumothorax
Negative Pleural Suction for Tube Thoracostomy in Patients With Chest Trauma
The purpose of this study is to determine whether the use of negative pleural suction in tube thoracostomy is more effective than water seal alone for the treatment of pneumothorax and/or hemothorax in patients with chest trauma.
- Conditions
- Hemothorax, Pneumothorax, Hemopneumothorax, Chest Injury Trauma Blunt
- Trial name
- NCT01864577
- Testing
- Negative Pleural Suction at -20 cm H2O, Water seal
- Where
- Colombia
- Volunteers
- 110 people
- Sponsor
- Universidad de Antioquia
Abdominal Injuries, Physical Abuse
Effectiveness of Contrast-Enhanced Ultrasound
The purpose of the study is to generate pilot data describing test characteristics of contrast enhanced ultrasound in young children with concern for abdominal trauma.
- Conditions
- Abdominal Injuries, Physical Abuse, Accidental Fall, Motor Vehicle Injury
- Trial name
- NCT03473249
- Testing
- Contrast-Enhanced Ultrasound using Lumason
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Abdominal Injuries
Utility of Abdominal Ultrasound in the Evaluation of Children With Blunt Trauma
The major goal of this project is to conduct a randomized controlled trial studying an initial evaluation strategy with abdominal ultrasound versus a strategy without abdominal ultrasound for the evaluation of children with blunt…
- Trial name
- NCT01540318
- Testing
- Abdominal Ultrasound (FAST examination)
- Where
- United States
- Volunteers
- 925 people
- Sponsor
- University of California, Davis
Radiofrequency Can be Used to Treat Splenic Trauma Because of Its Excellent Coagulation Hemostasis
RF-assisted Splenic Preservation VS Conventional Treatment of Blunt Splenic Injury.
Radiofrequency (RF) can be used to treat splenic trauma because of its excellent coagulation hemostasis. This study aimed to compare the efficacy of RF-assisted spleen-preserving surgery with that of conventional…
- Trial name
- NCT03890328
- Testing
- radiofrequency ablation
- Where
- China
- Volunteers
- 122 people
- Sponsor
- Southwest Hospital, China
Blunt Abdominal Trauma
Pelvic CT Imaging in Blunt Abdominal Trauma
Abdominopelvic CT (CTap) utilization rose significantly in blunt trauma patients over the last decade. However, the observed increases failed to reduce mortality or missed injury rates.
- Trial name
- NCT01828749
- Where
- United States
- Volunteers
- 230 people
- Sponsor
- Wake Forest University Health Sciences
Traumatic Blunt Chest and/or Blunt Abdominal Injury
Hemodynamic and Ventilatory Responses to Head-down Postural Drainage Position
The purpose of this study is to explore acute hemodynamic and ventilatory responses to head-down 30 degree postural drainage position in patients with blunt chest and/or abdominal injury in the traumatic intensive care unit.
- Trial name
- NCT01668875
- Testing
- Head down 30 degree postural drainage position, Horizontal supine lying
- Where
- Thailand
- Volunteers
- 11 people
- Sponsor
- Khon Kaen University
Splenic Rupture, Abdominal Injuries
Outcome After Conservative and Surgical Treatment of Splenic Injuries After Blunt Abdominal Trauma.
Retrospective study in order to investigate the outcome after conservative (with or without transcatheter arterial embolization) and surgical treatment of splenic injuries.
- Trial name
- NCT00910182
- Testing
- splenorrhaphy
- Where
- Switzerland
- Volunteers
- 200 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Blunt Injuries
Nonoperative Management Protocol in Patients With Blunt Splenic Injuries
This study was designed to explore the adverse events and associated risk factors before and after protocol-based NOM of BSI over a 12-year period in our institution.
- Trial name
- NCT03943355
- Testing
- Patient before cohort (2005-2010), Patient after cohort (2011-2016)
- Volunteers
- 399 people
- Sponsor
- Chang Gung Memorial Hospital