Clinical trials: Tooth Extraction
Healthy, Tooth Extraction
Capsaicin to Control Pain Following Third Molar Extraction
Capsaicin to Control Pain Following Third Molar Extraction Summary: This study will test the effectiveness of the drug capsaicin in controlling pain after third molar (wisdom tooth) extraction.
- Trial name
- NCT00088686
- Testing
- Capsaicin (Intramucosal Injection)
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- National Institute of Dental and Craniofacial Research (NIDCR)
Tooth, Impacted
Effect of Interceptive Strategies on the Clinical Outcome of Maxillary Impacted Canines
This study aims to investigate the effect of 3 randomly applied interceptive measures (slow maxillary expansion, extraction of deciduous canines and no intervention) on maxillary canine impaction in patients with early mixed…
- Trial name
- NCT05629312
- Testing
- Maxillary expansion, Extraction of deciduous upper canines
- Where
- Belgium
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Pain
Genetic Basis For Variation In NSAID Analgesia In A Clinical Model Of Acute Pain
This study will evaluate how genetic makeup contributes to the variation in people regarding their sensitivity to and experience of pain.
- Trial name
- NCT00115752
- Testing
- Valdecoxib, COX Inhibitor
- Where
- United States
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- National Institute of Nursing Research (NINR)
No Condition, Assessment of Healthy Volunteers
Usefulness of Intraosseous Anesthesia for Permanent Tooth Extraction Under GA in Pediatric Dental Treatment
The investigators are doing a study to see if a new way of giving local anesthesia during dental surgery can help children feel better after having a tooth removed under general anesthesia (when they are fully asleep).
- Trial name
- NCT07108439
- Testing
- Administration of intra-osseous local anesthesia before the extraction of a first permanent molar under general anesthesia
- Where
- Belgium
- Volunteers
- 80 people
- Sponsor
- University Hospital, Ghent
Healthy
Comparison of Modified Circular and Natural Tooth Brushing Methods in Effectiveness of Dental Plaque Removal
1. Plaque level in subjects using the Modified Circular method is different from that in subjects using natural tooth brushing method. 2.
- Trial name
- NCT03547531
- Testing
- Natural Tooth Brushing Method, Modified Circular Tooth Brushing Method
- Where
- Indonesia
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Prince of Songkla University
Dental Plaque
Plaque Removal Efficacy of a U-Shaped Sonic Power Toothbrush in Children
The objective of this single-use, examiner blinded, randomized, two-period, cross-over, IRB-approved clinical study is to evaluate the safety and plaque removal efficacy of AutoBrush®, a new children's 360° sonic toothbrush…
- Trial name
- NCT06300073
- Testing
- Experimental: U-shaped Power Toothbrush
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Lander Enterprises, LLC
Local Anesthetics, Tooth Extraction
Evaluation of Anesthetic Efficacy in Extraction on Mandibular Molars
To evaluate subjectively and objectively the quality and efficacy of local anesthetic block with mepivacaine in simple extraction of mandibular molar.
- Trial name
- NCT03106168
- Testing
- Extraction of mandibular molar
- Where
- Brazil
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Anesthesia, Local
Efficiency of Single Buccal Infiltration Versus Buccal and Intrapapillary Infiltration
Everyday practice in dentistry is based on giving the painless injection and achieving adequate local anesthesia. Various techniques of reducing injection pain in children can be broadly categorized as psychological and physical.
- Trial name
- NCT04458142
- Testing
- Single buccal infiltration
- Volunteers
- 25 people
- Sponsor
- Cairo University
Deep Caries Lesion of Pemanent Teeth
Outcome of Selective Caries Removal Performed by Undergraduate Students
Deep tooth decay can sometimes reach very close to the nerve of a tooth. Traditionally, dentists may remove all of the decayed tooth tissue, but removing too much tissue can increase the risk of exposing or damaging the nerve.
- Trial name
- NCT07765810
- Testing
- Selective caries removal to soft dentine, Selective Caries Removal to Firm/Leathery Dentine
- Where
- Jordan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- King Abdullah University Hospital
Dental Caries, Primary Teeth
Carie Care, Chemomechanical Caries Removal Technique in Primary Teeth
Chemomechanical caries removal systems have emerged as a possible valuable alternative to conventional rotary caries removal techniques in pediatric patients.
- Trial name
- NCT05538559
- Testing
- Chemomechanical caries removal by Carie-Care, Mechanical caries removal by Atraumatic Restorative Technique
- Where
- Egypt
- Volunteers
- 48 people
- Sponsor
- Hams Hamed Abdelrahman
Anesthesia
Comparison of the Effectiveness of Articaine Local Infusion and Lidocaine Nerve Block in Lower Posterior Tooth Extraction.
In this study 60 adult patients will participate and divided into two groups (30 for each). The first group will be anesthetized using 2 % lidocaine with 1:80,000 adrenaline by inferior alveolar nerve block technique, while the…
- Trial name
- NCT07048834
- Testing
- lidocaine local anesthetic drug, articaine local anesthetic drug
- Where
- Iraq
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Amjed Fouad Hussein
Liver Cirrhosis
Comparison of Chitosan, Ankaferd and Tranexamic Acid in Dental Extraction in Liver Pre-Transplant Children
The aim of the present study is: To assess the hemostatic effect of chitosan-based dressing, Ankaferd and Tranexamic acid after extraction in children with end stage liver diseases where the: Primary objective: is to evaluate…
- Trial name
- NCT06457360
- Testing
- tranexamic acid, Ankaferd Blood Stopper, Chitosan
- Where
- Egypt
- Volunteers
- 39 people
- Sponsor
- British University In Egypt
Tooth Extraction, Dental Anxiety
Comparison of Needle-Free Injection and Conventional Syringe for Tooth Extractions in Children
The goal of this clinical trial is to learn whether a needle-free injection system can make tooth extraction less stressful for children than a conventional dental syringe.
- Conditions
- Tooth Extraction, Dental Anxiety, Procedural Pain, Anesthesia, Dental
- Trial name
- NCT07548892
- Testing
- Needle-Free Jet Injection System, Conventional Syringe Injection
- Volunteers
- 60 people
- Sponsor
- Ondokuz Mayıs University
Extracting Own Teeth, Bone Substitutes
Study of Alveolar Bone Preservation Using Photobiomodulation Combined With Grafting With Scaffold Biomaterial
Bone graft added to the dental socket immediately after tooth extraction prevents atrophy and deformity of the bone at the site of element loss, enabling rehabilitation with implants.
- Trial name
- NCT06150456
- Testing
- extraction, low level laser therapy, Plenum® OSShp and Plenum® Guide
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Third Molar Extraction Surgery
Effect of Systemic Antibiotic Therapy on Postoperative Complications in Patients Undergoing Wisdom Teeth Removal Surgery.
59 medically healthy patients, who are scheduled for third molar extraction surgery and give informed consent for the trial, are operated using a split-mouth technique.
- Trial name
- NCT05142449
- Testing
- Amoxilan
- Where
- Austria
- Volunteers
- 59 people
- Sponsor
- Medical University of Graz
Analgesic Drugs, Pain Relief
Ibuprofen, Paracetamol Versus Placebo on Pain During Local Anesthetic Injection (RCT)
The Effect of Ibuprofen, Paracetamol versus Placebo on Pain during Local Anesthetic Injection and Following Dental Extraction in Primary Molars: A Randomized clinical trial
- Trial name
- NCT03184649
- Testing
- Ibuprofen, paracetamol
- Where
- Egypt
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Cairo University
Pain
Study Evaluating A Novel Ibuprofen Formulation In The Treatment Of Dental Pain
This study will compare the analgesic efficacy of a single-dose of a novel ibuprofen formulation to placebo and acetaminophen in the treatment of post-surgical dental pain following "wisdom" tooth (third molar) removal.
- Trial name
- NCT01216163
- Testing
- Novel Ibuprofen, Acetaminophen
- Where
- United States
- Volunteers
- 218 people
- Sponsor
- Pfizer
Hypertension
Assessment of Anesthetic Efficacy and Hemodynamic Stability of Two LA Drugs for Hypertensive Patients
Pain control in dentistry is an important factor for reducing the fear and anxiety associated with dental procedures. For tooth extraction, it is mandatory to use resources to manage pain and discomfort such as adequate…
- Trial name
- NCT06927726
- Testing
- 4% Articaine HCL With 1:100,000 Epinephrine, 3% plain mepivacaine HCL
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Tanta University
Tooth, Impacted
Bradykinin Receptors and Pain
This study will examine whether bradykinin receptors are produced at the site of wisdom tooth extraction and if they contribute to the amount of inflammation and pain that follows surgery.
- Trial name
- NCT00083356
- Testing
- Wisdom tooth extraction
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- National Institute of Nursing Research (NINR)
Healthy, Maxillary First Premolar Tooth Extraction
Gingival Crevicular Fluid Characterization During Orthodontic Treatment
During Orthodontic tooth movement, teeth are moved through alveolar bone under applied forces. The applied mechanical loading force must be transferred to the alveolar bone via periodontal ligament (PDL).
- Conditions
- Healthy, Maxillary First Premolar Tooth Extraction, Canine Retraction
- Trial name
- NCT04226469
- Testing
- Tooth movement
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Illinois at Chicago