Clinical trials: Testosterone
Testosterone, Angiographic Complexity
Serum Testosterone Level on Angiographic Complexity of Coronary Lesions in Premature Ischemic Egyptian Males
This study aims to investigate the association between serum testosterone levels and the angiographic complexity of coronary artery lesions in male patients under 45 years of age presenting with premature ischemic heart disease.
- Conditions
- Testosterone, Angiographic Complexity, Coronary Lesion, Premature Ischemia
- Trial name
- NCT07076771
- Testing
- Coronary Angiography, Syntax Score
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Sohag University
Klinefelter Syndrome
Sex Steroids Balance for Metabolic and Reproductive Health in Klinefelter Syndrome
The study seeks primarily to determine whether modulation of systemic and testicular sex steroids balance by aromatase inhibitors will positively affect the metabolic health and spermatogenesis of men with Klinefelter syndrome…
- Trial name
- KLIN-HEALTH (NCT05586802)
- Testing
- Anastrozole, Semaglutide, human chorionic gonadotropin
- Where
- Switzerland
- Volunteers
- 150 people
- Sponsor
- Georgios Papadakis
Appetitive Behavior, Pediatric Obesity
The Acute Effect of Protein or Carbohydrate Intake on Testosterone Levels and Food Intake in Children and Adolescent Boys
The purpose of this study was to determine the effect of acute protein and glucose intake on testosterone levels measured in adolescent boys and determine whether changes in testosterone levels are associated with alterations in…
- Trial name
- NCT03412136
- Testing
- Control, Glucose, Protein
- Where
- Canada
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Adolescent Depression
Adolescent Mood During Puberty and Testosterone
Starting at puberty, female adolescents are nearly three-times more likely to develop internalizing disorders, like depression, while male adolescents are two-times more likely to develop externalizing disorders, like attention…
- Trial name
- AMPT (NCT06072677)
- Testing
- Healthy Minds Program
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Fine Motor Skills, Testosterone Concentration
Effect of Exercise Training on Fine Motor Skills
Despite the importance of physical activity for adolescent physical development, the specific impact of different types of exercise training on fine motor skills and testosterone concentration is unknown.
- Trial name
- NCT04734964
- Testing
- exercise training
- Where
- Lithuania
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- Lithuanian Sports University
Secondary Hypogonadism
The Effect of Testosterone Replacement on the High Density Lipoprotein Cholesterol Subgroups
The study is designed to answer the following questions: 1. Is there any difference between the compositions of the HDL cholesterol subpopulations of patients with hypogonadism and the healthy controls. 2.
- Trial name
- NCT01454011
- Testing
- Testosteron 250mg injection, Testosterone 50mg transdermal application
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Gulhane School of Medicine
Health Services for Transgender Persons, Transgender Persons
Comparing Subcutaneous Testosterone to Intramuscular Testosterone in Gender Affirming Care of Transgender Male Adolescents
The trial studies the efficacy of subcutaneous (SQ) testosterone compared to intramuscular (IM) testosterone therapy during the first 6 months of pubertal induction in transgender male adolescents.
- Trial name
- NCT03864913
- Testing
- Testosterone injection, PedsQL questionnarie, Masculinizing effects questionnaire
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Primary or Secondary Hypogonadism, Constitutional Delay in Growth and Puberty (CDGP)
Pharmacokinetic Evaluation of Testosterone Gel (1%)
Measure and evaluate the level of testosterone in blood, and determine the safety and tolerability following daily applications of testosterone gel.
- Trial name
- NCT00193700
- Testing
- Testosterone Gel (1%)
- Where
- 9 sites in United States
- Sponsor
- Solvay Pharmaceuticals
Cancer Survivor, Sexual Dysfunction
Low-Dose Testosterone in Improving Libido in Postmenopausal Female Cancer Survivors
RATIONALE: The hormone testosterone may improve the libido (sex drive) in women. It is not yet known whether testosterone is effective in improving libido in female cancer survivors.
- Conditions
- Cancer Survivor, Sexual Dysfunction, Sexuality and Reproductive Issues, Unspecified Adult Solid Tumor, Protocol Specific
- Trial name
- NCT00075855
- Testing
- therapeutic testosterone
- Where
- 16 sites in United States
- Volunteers
- 150 people
- Sponsor
- Alliance for Clinical Trials in Oncology
Transgender, Transgenderism
Cardiometabolic Health in Transgender Males
Transgender individuals are those with a gender identity opposite the sex they were assigned at birth. Approximately 1% of the population is transgender, equating to ~60,000 transgender Wisconsinites.
- Trial name
- NCT04977765
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Medical College of Wisconsin
Gender Identity, Gender Dysphoria in Adolescents and Adults
Puberty, Testosterone, and Brain Development
Transmasculine youth (female sex assigned at birth, male gender identity) who begin clinical gender affirming hormone therapy (GAHT) with testosterone (T) may experience changes in headache.
- Conditions
- Gender Identity, Gender Dysphoria in Adolescents and Adults, Headache, Transgender
- Trial name
- NCT06670053
- Testing
- Testosterone
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Colorado, Denver
Precocious Puberty
Treatment of Boys With Precocious Puberty
This study is a continuation of two previous studies conducted at the NIH. The first study , "Treatment of True Precocious Puberty with a Long-Acting Lutenizing Hormone Releasing Hormone Analog (D-Trp(6)-Pro(9)-Net-LHRH)" had…
- Trial name
- NCT00001202
- Testing
- Spironolactone, Testolactone, Deslorelin
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Metastatic Castration-resistant Prostate Cancer, Bone Metastases
A Research Called CREDIT Studies How Safe the Study Treatment Radium-223 is and How Well it Works in Chinese Men With Advanced Prostate Cancer That Has Spread to the Bones and Does Not Respond to Treatments for Lowering Testosterone Levels
This is an observational study in which data from Chinese men with metastatic castration-resistant prostate cancer that has spread to the bones and who start Radium-223 therapy is studied.
- Trial name
- CREDIT (NCT05301062)
- Testing
- Radium-223 dichloride (Xofigo, BAY88-8223)
- Where
- China
- Volunteers
- 8 people
- Sponsor
- Bayer
Anxiety Disorder, Depression
Evaluation of Association Between Testosterone Levels, Dementia, and Adverse Mental Health Outcomes
This study evaluates the association between testosterone levels and risk of dementia and adverse mental health outcomes (e.g. depression and anxiety).
- Conditions
- Anxiety Disorder, Depression, Genetic Disorder, Hematopoietic and Lymphoid Cell Neoplasm
- Trial name
- NCT04743466
- Testing
- Electronic Health Record Review
- Where
- United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Klinefelter Syndrome, 47,XXY
Cardiometabolic Profiles of Boys With Klinefelter Syndrome
This study plans to learn more about how to measure the way the the body's energy system works in boys with Klinefelter syndrome, including the heart, lungs, muscles, and liver.
- Conditions
- Klinefelter Syndrome, 47,XXY, Sex Chromosome Aneuploidy, XXY Syndrome
- Trial name
- NCT02723305
- Testing
- No intervention
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- University of Colorado, Denver
Hyperandrogenism
Sleep-wake Changes of Luteinizing Hormone Frequency in Pubertal Girls With and Without High Testosterone
The purpose of this study is to determine whether sleep-wake changes of luteinizing hormone pulse frequency are different in early pubertal girls with high testosterone levels compared to early pubertal girls with normal…
- Trial name
- CRM005 (NCT00930007)
- Testing
- Blood sampling
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Bone Metabolism
The Effect of Testosterone Replacement on Bone Mineral Density in Boys and Men With Anorexia Nervosa
Decreased bone strength is a common and serious medical problem present in many people with anorexia nervosa. Men with anorexia nervosa have lower levels of gonadal steroids such as testosterone.
- Trial name
- NCT00853502
- Testing
- testosterone cypionate
- Where
- United States
- Sponsor
- Massachusetts General Hospital
Prostate Cancer
[18F]-Fluoro-2-Deoxy-D-Glucose and -[18F] Dihydro-Testosterone Pet Imaging in Patients With Progressive Prostate or Salivary Gland Cancer
This study will use PET scans, which is a type of x-ray test that uses a radiotracer, to see whether these scans may be better able to find places in the body where your prostate cancer may have spread.
- Trial name
- NCT00588185
- Testing
- [18F]-Fluoro-2-Deoxy-D-Glucose and -[18F] Dihydro-Testosterone
- Where
- 7 sites in United States
- Volunteers
- 300 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Hypogonadism
Evaluation of Testosterone Nasal Gel in Hypogonadal Boys
PK study to evaluate serum levels of testosterone post nasal delivery in two cohorts of hypogonadal boys.
- Trial name
- NCT03345797
- Testing
- Testosterone Nasal Gel [Natesto]
- Where
- 3 sites in United Kingdom
- Volunteers
- 8 people
- Sponsor
- Acerus Biopharma Inc.
General Anesthesia, Testosterone
Comparison of the Effect of Testosterone Administered for Micropenis Hypospadias Surgery With Bispectral Index
The aim of this observational study is to learn the effects of hormone therapy (testosterone) applied in micropenis hypospadias surgery on the depth of anesthesia under general anesthesia.
- Conditions
- General Anesthesia, Testosterone, BIS
- Trial name
- NCT06606496
- Testing
- Bispectral index (BIS)
- Where
- Turkey (Türkiye)
- Volunteers
- 22 people
- Sponsor
- Namik Kemal University