Clinical trials: Skin Scarring
Scar
Postoperative Skin Surface Tension Relaxing in Prevention of Facial Surgical Skin Scarring
The purpose of this study is to evaluate the efficacy and safety of early postoperative skin surface reduction in improving scar formation after facial surgery.
- Trial name
- NCT03842644
- Testing
- Tension reduction device
- Where
- China
- Volunteers
- 55 people
- Sponsor
- XiaoXi Lin
Acne Vulgaris, Atrophic Acne Scars
Adapalene 0.3% - Benzoyl Peroxide 2.5% Gel and Risk of Formation of Atrophic Acne Scars
This was a multi-centre, randomized, investigator blinded, vehicle controlled trial using intra-individual comparison (right half-face versus left half-face).
- Trial name
- OSCAR (NCT02735421)
- Testing
- ABPO Forte Gel, Vehicle gel
- Where
- 7 sites in Canada, France
- Volunteers
- 67 people
- Sponsor
- Galderma R&D
Skin Regrafting; Donor Site of Skin Grafting; Vancouver Scar Scale
Management of Skin Graft Donor Site Wound in Aged Patient
The complication of donor site in skin grafting often acts as a causing factor for extended treatment period. The elderly individuals tend to be afflicted by impaired wound healing.
- Trial name
- NCT05371171
- Testing
- skin graft, no skin graft
- Where
- Taiwan
- Volunteers
- 15 people
- Sponsor
- Taipei Medical University WanFang Hospital
Burn Scar, Scar
Mechanistic Basis of Ablative Carbon Dioxide Laser in Treating Hypertrophic Scars
This is an observational cohort study which will look at the biomarkers from blood and tissue sample for adult patients with hypertrophic scarring due to burns/trauma incident over 12 months from date of recruitment.
- Trial name
- SMOOTH (NCT04736251)
- Where
- United Kingdom
- Volunteers
- 60 people
- Sponsor
- Naiem Moiemen
Hypertrophic Scars, Keloids
Scar Gel Product Family Clinical Investigation
The purpose of this PMCF investigation is to determine whether there are differences between the two formulations (Dermatix and Dermatix Ultra) in improving keloid and hypertrophic scars clinical symptoms and in the overall scar…
- Trial name
- NCT07684573
- Testing
- Dermatix, Dermatix Ultra
- Volunteers
- 150 people
- Sponsor
- Hanson Medical, Inc.
Keloids, Keloids Scars
A Prospective Observational Clinical Study on Exploring the Value of Surgical Excision Combined With 32P Application in the Treatment of Keloids and the Factors Affecting the Prognosis of Combined Therapy
Keloids are non-cancerous (benign) growths on the skin. They form after an injury, when the skin makes too much connective tissue that thickens and hardens. These keloids cause big problems for people.
- Trial name
- NCT07413497
- Volunteers
- 401 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Burns
Phase III Study With an Autologous Dermo-epidermal Skin Substitute for the Treatment of Burns in Adults and Adolescents
This multicentre phase III clinical trial will target adults and adolescents of 12 years and older with severe burns to confirm the efficacy and functionality of denovoSkin™ in achieving wound closure and reducing scarring in…
- Trial name
- NCT06745557
- Testing
- denovoSkin(TM), STSG
- Where
- 19 sites in Belgium, France and 7 more
- Volunteers
- 70 people
- Sponsor
- CUTISS AG
Scarring
Medipore Tape Study
This is a prospective, single-blinded, two-arm, randomized, parallel, pragmatic, effectiveness trial that will enroll patients undergoing arthroscopic anterior cruciate ligament reconstruction in order to evaluate the efficacy of…
- Trial name
- NCT02676115
- Testing
- Standard Post Operative Skin Care, Medipore Tape
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Acne, Scar
Comparison of Treatments for Atrophic Acne Scars
Acne scars have high prevalence, significant impact on quality of life and are a therapeutic challenge for dermatologists. Previous studies have shown promising results for the treatment of acne scars with non-ablative fractional…
- Trial name
- NCT02025088
- Testing
- Laser, Microneedling
- Where
- Brazil
- Volunteers
- 23 people
- Sponsor
- Thaís Hofmann Cachafeiro
Atrophic Acne Scars
Comparison of Efficacy of Carbon Dioxide Laser With Subcision Versus Platelet-Rich Plasma Bio-Fillers With Subcision for the Treatment of Atrophic Acne
This randomized controlled trial compared two combined treatment approaches for atrophic acne scars. A total of 100 patients aged 15-45 years were enrolled from the Department of Dermatology, Lahore General Hospital, Lahore, and…
- Trial name
- NCT07752186
- Testing
- Platelet-Rich Plasma Bio-Filler With Subcision, Fractional Carbon Dioxide Laser With Subcision
- Where
- Pakistan
- Volunteers
- 100 people
- Sponsor
- Lahore General Hospital
Keloid
Retrospective Study of Keloid Disorder
Purpose of this retrospective study is to review and analyze the information and data that has been already been generated during the course of routine practice of medicine by the investigators from 2007 up until Sept 1, 2016…
- Trial name
- NCT02923596
- Testing
- History of prior Surgery, History of Radiation Therapy
- Where
- 2 sites in United States
- Volunteers
- 5,000 people
- Sponsor
- Tirgan, Michael H., M.D.
Pelvic Floor Disorders
Treatment of Scars and Dysfunctions of the Pelvic Floor in Postpartum
Recruitment of patients who have suffered third- and fourth-degree perineal tear during childbirth, and who have given birth at the Hospital Universitario Marqués de Valdecilla (Santander, Spain).
- Trial name
- NoRFor (NCT04098965)
- Testing
- Pysiotherapy techniques, physician treatment
- Where
- Spain
- Volunteers
- 90 people
- Sponsor
- Universidad de León
Fibrosis, Skin Scarring
Light Emitting Diode-Red Light (LED-RL) Phototherapy for Skin Scarring Prevention
Skin scarring (fibrosis) is a common complication in the wound healing process and remains a therapeutic challenge. Scar formation often occurs following injury to the skin such as surgery, trauma, and burns.
- Conditions
- Fibrosis, Skin Scarring, Skin Wound, Hypertrophic Scar
- Trial name
- NCT03795116
- Testing
- LED-RL phototherapy, Mock irradiation
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- State University of New York - Downstate Medical Center
Keloids
Efficacy and Safety of Intralesional 5-Fluorouracil and Triamcinolone Acetonide in Keloids and Hypertrophic Scars
Pathological scars like keloids and hypertrophic scars (HTS's) cause significant aesthetic, symptomatic and psychological issues to patients. Treatment is challenging with no universally accepted "gold standard" method.
- Trial name
- NCT07034482
- Testing
- Intralesional Triamcinolone 5 mg/ml, Intralesional 5-fluorouracil
- Where
- Nepal
- Volunteers
- 41 people
- Sponsor
- Maharajgunj Medical Campus
Hypertrophic Scars
Prevention of Hypertrophic Scars or Keloids
Keloids and hypertrophic scars are not major illness. However, their effects can be from causing pain and itch which substantially interfere daily activity to as severe as causing deformity and other functional impairment.
- Trial name
- RCT (NCT00849004)
- Testing
- silicone gel, silicone sheet, paper tape
- Where
- Taiwan
- Volunteers
- 75 people
- Sponsor
- Kaohsiung Veterans General Hospital.
Scar Keloid
Intralesional Triamcinolone Acetonide and Its Combination With 5-fluorouracil in Keloids and Hypertrophic Scars
Summary: Keloids and hypertrophic scars are benign fibrous growth, differing mainly by overgrowth beyond the initial defect in keloid whereas hypertrophic scar is confined to initial lesion and tends to regress over the years.
- Trial name
- NCT04812626
- Testing
- 5-Fluorouracil
- Where
- Nepal
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- B.P. Koirala Institute of Health Sciences
Keloid
High Dose Rate Brachytherapy for Treatment of Keloids
This prospective study evaluates the outcome of surgical excision with adjuvant high-dose-rate brachytherapy for the treatment of recalcitrant keloids. Main outcomes are recurrence rate, scar quality and physical complaints.
- Trial name
- NCT02005055
- Testing
- Surgical excision with adjuvant high-dose-rate brachytherapy
- Where
- Netherlands
- Volunteers
- 43 people
- Sponsor
- Amsterdam UMC, location VUmc
Joint Contracture, Contracture
Recurrence of Extremity Joint Contracture After Z-Plasty Versus Full-Thickness Skin Graft
The purpose of this study is to compare how often joint contractures in the arms and legs come back after two common types of reconstructive surgery: Z-plasty and full-thickness skin graft (FTSG).
- Conditions
- Joint Contracture, Contracture, Cicatrix, Burn Scar Contractures
- Trial name
- NCT07885046
- Testing
- Z-Plasty, Full-Thickness Skin Graft
- Volunteers
- 300 people
- Sponsor
- Universitas Sebelas Maret
Burns
The Burn Glove Trial - Hand Burn Dressing Pilot
Specific Aim 1: To determine if one of three burn dressings provides a less painful healing experience for partial thickness hand.
- Trial name
- NCT02318056
- Testing
- Aquacel® Ag Burn Glove, Mepilex® Transfer Ag, antibiotic
- Where
- United States
- Sponsor
- Southern Illinois University
Keloid, Keloid Scar Following Surgery
Post-Surgical Injection With Triamcinolone Versus Triamcinolone/Fluorouracil in Treatment of Keloids
There have been many modalities utilized in the treatment of keloids of the head and neck, however none have been universally successful.
- Trial name
- NCT04710719
- Testing
- Triamcinolone Injection, Triamcinolone Injection and 5-fluorouracil injection
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Our Lady of the Lake Hospital