Clinical trials: Sedation
Dental Caries, Tooth Extraction
Treating Children With Extensive Dental Needs
The goal of this qualitative study, using Grounded Theory, is to gain deeper knowledge about dentists' experiences from treating in particular young children with an extensive treatment need (mainly due to caries).
- Conditions
- Dental Caries, Tooth Extraction, Conscious Sedation, Attitude
- Trial name
- NCT06863103
- Where
- Sweden
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Malmö University
Anesthesia, Anesthesia; Adverse Effect
EEG-guided Propofol Sedation Versus Standard Care for Oesophagogastroduodenoscopy and Colonoscopy in Children
The goal of this clinical trial is to compare electroencephalogram (EEG) guided propofol sedation versus standard care in paediatric patients aged 6-16 undergoing oesophagogastroduodenoscopy and colonoscopy.
- Conditions
- Anesthesia, Anesthesia; Adverse Effect, Anesthesia Emergence Delirium, Sedation Complication
- Trial name
- EPOC (NCT06225037)
- Testing
- Sedline EEG monitoring, Sedline EEG with output concealed
- Where
- Singapore
- Volunteers
- 50 people
- Sponsor
- KK Women's and Children's Hospital
Music Therapy, Music Therapy for Pain and Sedation
Effect of Music Therapy on the Quality of Recovery
Background: The use of music in operations is increasing due to its painless, safe, inexpensive, and the potential to improve patient outcomes.
- Conditions
- Music Therapy, Music Therapy for Pain and Sedation, Postoperative Period, Perioperative Period
- Trial name
- MTonR (NCT06874972)
- Testing
- Music played
- Where
- Bhutan
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Ministry of Health, Bhutan
Pediatric, ED95
The ED95 of Single Intravenous Bolus Remimazolam Besylate in Pediatric Patients During General Anesthesia Induction
Due to the incomplete development of systems and low pain thresholds in the pediatric population, good general anesthesia is required during the perioperative period to ensure the smooth progress of the surgery.Propofol is often…
- Conditions
- Pediatric, ED95, Sedation, General Anesthesia
- Trial name
- NCT06061159
- Testing
- Remimazolam besylate
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital of Wenzhou Medical University
Pediatric, Gastroscopy
Effect of Esketamine on 95% Induction Dose of Remimazolam
As an invasive operation, gastroscopy will cause children's nervousness, anxiety and uncooperative behavior, and even lead to the risk of bleeding and perforation, which will also affect the accuracy of the examination…
- Conditions
- Pediatric, Gastroscopy, ED95, Sedation
- Trial name
- EEIDR (NCT06303037)
- Testing
- Remimazolam besylate and low-dose Esketamine, Remimazolam besylate and Medium dose Esketamine
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital of Wenzhou Medical University
Sedation, BIS
Evaluation of Sedation Depth and Reliability With Integrated Pulmonary Index (IPI) Follow-up in Pediatric Radiological Interventions
In this study, we aimed to investigate the predictability of possible respiratory complications and the effect of the addition of the integrated pulmonary (EPI) score to the evaluation of the patient's respiratory index status in…
- Conditions
- Sedation, BIS, Integrated Pulmonary Index
- Trial name
- IPI (NCT06343896)
- Testing
- monitorization reliability
- Where
- Turkey (Türkiye)
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Sedation Complication
Validation of a Processed EEG Device for Monitoring Sedation in PICU
The goal of this prospective observational study is to validate pEEG as a monitoring tool for the analgosedation level in mechanically-ventilated critically ill children, receiving or not-receiving NMBAs.
- Trial name
- NCT05969483
- Testing
- pEEG monitoring
- Where
- Italy
- Volunteers
- 150 people
- Sponsor
- Azienda Ospedaliera di Padova
Dental Sedation, Passive Smoking
The Effects of Passive Smoking on Vital Signs, Anxiety, and Recovery Times in Children Undergoing Primary Tooth Extraction Treatment Under Sedation
The aim of this clinical study is to evaluate the effects of passive smoking on the vital parameters of children undergoing primary tooth extraction under sedation and to assess their anxiety levels throughout the process until…
- Trial name
- NCT06780189
- Testing
- Tooth Extraction and Post-Procedure Monitoring Under Sedation in Children Exposed to Passive Smoking, Tooth Extraction and Post-Procedure Monitoring Under Sedation in Children Not Exposed to Passive Smoking
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ondokuz Mayıs University
Sedation
Sedation MRI - Propofol Versus Propofol-Ketamin in Children
Children < 10 years of age often need deep sedation or anaesthesia to allow elective diagnostic magnetic resonance imaging; standard routine protocols are 1.
- Trial name
- NCT01519154
- Testing
- Propofol, Ketamine-Propofol
- Where
- Switzerland
- Volunteers
- 347 people
- Sponsor
- Achim Schmitz
Pediatric, Sedation
Nebulized Dexmedetomidine as a Premedication for Gastrointestinal Endoscopy in Pediatric Patients
This study aims to demonstrate that the application of nebulized dexmedetomidine to patients during pediatric upper gastrointestinal endoscopic procedures will significantly reduce the gag reflex and enhance both patient and…
- Trial name
- NCT06218797
- Testing
- a routine sedation protocol, Nebulized with dexmedetomidine
- Where
- Turkey (Türkiye)
- Volunteers
- 108 people
- Sponsor
- Ondokuz Mayıs University
Sedation
Comparison of Oral Chloral Hydrate and Combination of Intranasal Dexmedetomidine and Ketamine for Procedural Sedation in Children
In Korea, oral chloral hydrate is still widely used for pediatric procedural sedation. The primary objective of the study is to evaluate the effect of intranasal dexmedetomidine (2mcg/kg) and ketamine (3mg/kg) on the…
- Trial name
- NCT04820205
- Testing
- Intranasal dexmedetomidine and ketamine, Oral chloral hydrate
- Where
- South Korea
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Autism Spectrum Disorder, Dexmedetomidine
Esketamine Combined With Dexmedetomidine Sedation in Head MRI Examination of Children With Autism Spectrum Disorder
Objective: To investigate the use of ketamine combined with dexmedetomidine for sedation in children with autism spectrum disorder, Methods:aged 2-6 years,, ASA grade I or II.
- Conditions
- Autism Spectrum Disorder, Dexmedetomidine, Esketamine, Sedation
- Trial name
- NCT06633315
- Testing
- low dos dexmedetomidine, high dos dexmedetomidine, dexmedetomidine and esketamine
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Maternal and Child Health Hospital of Hubei Province
Procedural Sedation, EEG
Factors Associated With Successful Completion of MRI in Children Undergoing a Vigil Sedation With Dexmedetomidin
This is a retrospective cohort study aiming to determine whether the use of Dexmedetomidine (DEX) to sedate children prior to MRI scanning is more or less effective in children with autism spectrum disorders or other…
- Conditions
- Procedural Sedation, EEG, MRI
- Trial name
- RIDEX (NCT06203522)
- Testing
- Data collection of successful completion of MRI
- Where
- France
- Volunteers
- 81 people
- Sponsor
- Centre Hospitalier Régional Metz-Thionville
Sedation, Pediatric Anesthesia
Frequency of Adverse Events in Pediatric Patients Receiving Sedation for Magnetic Resonance Imaging
Introduction:The application of anesthesia outside the operating room for pediatric patients has increased in recent years. For diagnostic and treatment follow-up purposes, magnetic resonance imaging (MRI) requires the pediatric…
- Conditions
- Sedation, Pediatric Anesthesia, Magnetic Resonance Imaging, Adverse Effect
- Trial name
- NCT06467045
- Testing
- Pediatric patients who received sedation for magnetic resonance imaging
- Where
- Turkey (Türkiye)
- Volunteers
- 500 people
- Sponsor
- Sisli Hamidiye Etfal Training and Research Hospital
Sedation Complication
Comparison Between Intranasal vs Intravenous Dexmedetomidine for EEG Sedation of Children With Behavior Disorders.
The aim of the project was to compare the efficacy and safety of intranasal (IN) and intravenous (IV) dexmedetomidine (DEX) in procedural sedation for electroencephalogram (EEG) in pediatric patients with behavioural disorders.
- Trial name
- NCT06434428
- Testing
- dexmedetomidine (IV), dexmedetomidine (IN)
- Where
- Italy
- Volunteers
- 48 people
- Sponsor
- Azienda Ospedaliera di Padova
Pediatric Sedation
Evaluation of the Efficacy of Oxygen Therapy and Clinical Feasibility of High Flow Nasal Cannula During Moderate and Deep Sedation in Pediatric Patients
The investigators evaluate the efficacy and safety of routine administration of oxygen during moderate or deep sedation in pediatric patients.
- Trial name
- NCT04852432
- Testing
- high flow nasal cannula, nasal prong
- Where
- South Korea
- Volunteers
- 258 people
- Sponsor
- Seoul National University Hospital
Sedation
Precedex Special Investigation (in Pediatric Patients)
Secondary Data Collection:To confirm the safety and effectiveness profiles under the actual medical practice of Precedex in Japan.
- Trial name
- NCT04040439
- Testing
- Dexmedetomidine Hydrochloride
- Where
- Japan
- Volunteers
- 111 people
- Sponsor
- Pfizer
Dental Caries in Children, Pediatric Dental Sedation
Comparing Pediatric Dental Oral Sedation Outcomes With and Without Meperidine in Children Aged 3-7 Years
The primary objective of this randomized controlled trial is to assess the effects of oral sedation using midazolam and hydroxyzine with and without meperidine (a narcotic) on sedation outcomes in pediatric dental patients…
- Conditions
- Dental Caries in Children, Pediatric Dental Sedation, Meperidine, Hydroxyzine
- Trial name
- NCT04068948
- Testing
- Meperidine, Hydroxyzine, Midazolam
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- University of Washington
Clinical CT Abdomen/Pelvic With Oral Contrast and Sedation
CT Residual Gastric Fluid Volume
Hypothesis: The investigators hypothesize that more than 50% of the patients receiving enteric contrast material (ECM) < 2 hours of anesthesia/sedation would have residual gastric fluid volume (GFV) > 0.4 ml/kg.
- Trial name
- NCT02239068
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Prematurity, Magnetic Field Exposure
Lateral Position MRI in Preterm Infants, an Observational Study
The goal of this observational study is to evaluate safety of sedation in lateral position in premature babies undergone MRI. The main question it aims to answer are: number of apneas during sedation Maintenance of eupnea during…
- Conditions
- Prematurity, Magnetic Field Exposure, Sedation Complication
- Trial name
- MRIOPS (NCT05776238)
- Where
- Italy
- Volunteers
- 22 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS