Clinical trials: Scoliosis Correction
Erector Spinae Block, Analgesia
Ultrasound Guided Bilateral Erector Spinae Block as Analgesia for Adolescent Idiopathic Scoliosis Correction
Scoliosis is a structural, tridimensional deformity of the spine. Characterized by lateral curvature and rotation of the vertebrae with functional limitations and cosmetic problems, idiopathic scoliosis, which accounts for 75% to…
- Conditions
- Erector Spinae Block, Analgesia, Scoliosis Idiopathic
- Trial name
- NCT04336046
- Testing
- erector spinae block, normal saline, Bupivacaine
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Tanta University
Ultra-short-term, Iron Deficiency Anemia
Effect of Ultra-short-term Treatment of Patients With Iron Deficiency or Anemia Undergoing Adolescent Scoliosis Correction
Scoliosis is a condition in which there is curvature of the spine occurring in the lateral plane. It occurs in structural forms, characterized by a fixed curve, and "functional" forms, characterized by a flexible or correctable…
- Conditions
- Ultra-short-term, Iron Deficiency Anemia, Scoliosis Idiopathic
- Trial name
- NCT04343170
- Testing
- ferric carboxymaltose , α erythropoietin, vitamin B12, oral folic acid
- Where
- Egypt
- Volunteers
- 44 people
- Sponsor
- Tanta University
Adolescent Idiopathic Scoliosis
Impact of Metal Density on Deformity Correction for Adolescent Idiopathic Scoliosis
A retrospective analysis to ascertain the correlation between metal density and deformity correction among individuals with adolescent idiopathic scoliosis.
- Trial name
- NCT04175145
- Testing
- Posterior spinal instrumentation
- Volunteers
- 96 people
- Sponsor
- Ghurki Trust and Teaching Hospital
Idiopathic Adolescent Scoliosis, Idiopathic Juvenile Scoliosis
Minimal Invasive Scoliosis or Open Surgery
Surgical treatment for idiopathic scoliosis usually involves open surgery from the back (posterior approach). This method corrects the curve and stabilizes the spine using screws and rods, followed by a fusion of the treated…
- Trial name
- MISCOS (NCT07203586)
- Testing
- Minimally invasive scoliosis surgery, Traditional open scoliosis surgery group
- Where
- Sweden
- Volunteers
- 180 people
- Sponsor
- Uppsala University
Scoliosis
Effect of Intraoperative Paravertebral Block on Postoperative Pain and Recovery in Patients Undergoing Mechanical Correction for Scoliosis
Pain management after scoliosis surgery is challenging for the anesthesiologists. This surgery causes severe postoperative pain and patients undergoing these operations are children or adolescents who are increased pain sensation…
- Trial name
- NCT04773509
- Testing
- Paravertebral block
- Where
- South Korea
- Volunteers
- 32 people
- Sponsor
- Yonsei University
Adolescent Idiopathic Scoliosis
Evaluating the Effectiveness of Posture Correction Girdle for Adolescents With Early Scoliosis
Through the ITF-Tier 3 project (ITS/ 237/ 11), a prototype of the posture correction girdle based on the clinical, textile science, material and ergonomics engineering analyses has been developed for preteen and teenage girls…
- Trial name
- NCT03929042
- Testing
- Posture correction girdle
- Where
- Hong Kong
- Volunteers
- 50 people
- Sponsor
- The University of Hong Kong
Adolescent Idiopathic Scoliosis (AIS)
Feasibility Study of MID-C for AIS
Adolescent idiopathic scoliosis (AIS) is a common disorder of unknown etiology in which the vertebrae and discs gradually develop a curvature that is first detected in patients between 11 and 20 years of age.
- Trial name
- MID-C (NCT03071445)
- Where
- 3 sites in Hungary, Romania
- Volunteers
- 13 people
- Sponsor
- Apifix
Scoliosis Idiopathic, Scoliosis; Adolescence
Back Muscle Function in Adolescents With Idiopathic Scoliosis
The function and asymmetry of back muscles will be examined in different positions and with specific spinal corrections based on scoliosis pattern and according to the "Schroth method" in adolescents with idiopathic scoliosis.
- Trial name
- NCT05961228
- Testing
- exercise
- Where
- Israel
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Haifa
Scoliosis, Spine Deformity
Post-Hoc Cost-Utility Analysis of Ultrasound-Guided Erector Spinae Plane (ESP) Block Versus Total Intravenous Anesthesia (TIVA) in Posterior Scoliosis Correction Surgery: Evidence From the Egyptian EQ-5D-5L Value Set
Posterior scoliosis correction surgery is associated with sever postoperative pain that necessitate high perioperative opioid doses to alleviate pain .
- Trial name
- NCT07470567
- Where
- Egypt
- Volunteers
- 44 people
- Sponsor
- National Bank Hospital
Scoliosis
IRB-HSR# 14145 R,S Methadone: Analgesia and Pharmacokinetics in Adolescents Undergoing Scoliosis Correction
This is a pilot study to determine the pharmacokinetics of (R,S) methadone in adolescents. A total of approximately 15 patients will be required.
- Trial name
- NCT01205256
- Testing
- methadone
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- University of Virginia
Scoliosis; Adolescence, Anesthesia Recovery Period
IV Lidocaine Analgesia in Pediatric Scoliosis Surgery
Surgical correction of scoliosis in children is a long procedure, with an equivalently long recovery time, that is commonly performed at BC Children's Hospital.
- Trial name
- P-IVLT (NCT04069169)
- Testing
- Lidocaine, Saline Solution
- Where
- Canada
- Volunteers
- 48 people
- Sponsor
- University of British Columbia
Scoliosis, Idiopathic Scoliosis
Effect Of Scientific Exercise Approach For Scoliosis Versus Barcelona Scoliosis Physical Therapy School On Correction Of Adolescent Idiopathic Scoliosis
Adolescent idiopathic scoliosis AIS is the usual diagnosis made in healthy children with a spinal curvature of unknown cause of least 10 degrees but less than 50 degrees.
- Conditions
- Scoliosis, Idiopathic Scoliosis, Adolescent Scoliosis
- Trial name
- NCT06806020
- Testing
- SEAS approach, BSPTS school
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Kafrelsheikh University
Scoliosis Idiopathic
POSTOPERATIVE OPIOID-SPARING EFFECT OF INTRAOPERATIVE PAIN MONITORING USING THE ANALGESIA NOCICEPTIVE INDEX (ANI) DURING IDIOPATHIC SCOLIOSIS CORRECTION IN CHILDREN.
Anaesthesia is often performed using a balanced technique by administering both opioids and anaesthetics agents. Intraoperative opioid administration is still relying on simple parameters such as heart rate and blood pressure…
- Trial name
- OpiSpANI (NCT04047225)
- Testing
- THE ANALGESIA NOCICEPTIVE INDEX (ANI)
- Where
- France
- Volunteers
- 260 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Adolescent Idiopathic Scoliosis
Safety and Efficacy of Posture Correction Girdle for Adolescent With Early Scoliosis
For AIS, the caring of patients with spinal deformities has a long and varied history. Severe spinal deformities can greatly reduce pulmonary and cardiac functions, which may lead to death from cardiopulmonary failure.
- Trial name
- NCT01776736
- Testing
- Posture Correction Girdle
- Where
- China
- Volunteers
- 50 people
- Sponsor
- The Hong Kong Polytechnic University
Idiopathic Scoliosis
Study of DDAVP Combined With TXA on the Blood Loss and Transfusion Need During and After Scoliosis Correction Surgery
Intraoperative administration of tranexamic acid (TXA,T) reduces significantly blood loss and blood transfusion requirements during spinal posterior fusion in adolescents with scoliosis.
- Trial name
- NCT02084342
- Testing
- tranexamic acid and sodium chloride injection, normal saline, desmopressin acetate injection
- Volunteers
- 60 people
- Sponsor
- Liu Weifeng
Scoliosis
Trial of Posture Correction Girdle for Adolescents With Early Scoliosis
Adolescent idiopathic scoliosis (AIS) is a prevalent chronic condition that gradually leads to the three dimensional deformity of the spine. Spine curvature increases in youths as puberty progresses.
- Trial name
- NCT03332251
- Testing
- Posture Correction Girdle
- Where
- China
- Volunteers
- 15 people
- Sponsor
- The Hong Kong Polytechnic University
Scoliosis Idiopathic Adolescent
The Effect of Dexamethasone Administration Route and Local Anesthetic Concentration on Pain, Inflammatory Response, and Neuromonitoring in Children Undergoing Scoliosis Correction
Scoliosis correction surgery in children is a complex procedure with significant risks, including postoperative pain, inflammatory response, and potential neurological complications.
- Trial name
- NCT06789029
- Testing
- perineural Dexamethasone, intravenous Dexamethasone
- Where
- Poland
- Volunteers
- 60 people
- Sponsor
- Poznan University of Medical Sciences
Wounds
The Use of Dermabond Versus Standard Staple for Wound Closure in Children With Neuromuscular Scoliosis Undergoing Spinal Deformity Correction Surgery
This is a prospective, Phase II (hypothesis generating) randomized pilot study investigating the efficacy of using Dermabond as a method of final wound closure as compared to the standard staple method in children with…
- Trial name
- NCT01135940
- Testing
- 2-octylcyanoacrylate (Dermabond) closure, Standard staple closure
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- University of British Columbia
Asses Radiological Efficacy of Posterior Approach Regarding Correction of Cobb Angle Post Operative . • Asses, Scoliosis Idiopathic Adolescent Treatment
Surgical Outcomes and Complications of Posterior Spinal Fusion in Adolescent Idiopathic Scoliosis
Adolescent idiopathic scoliosis (AIS) is the most common form of scoliosis representing about 80-90% of all idiopathic scoliosis cases , characterized by lateral curvature of the spine of 10 degrees or more in children 10-18…
- Trial name
- Scoliosis (NCT07092917)
- Where
- Egypt
- Volunteers
- 25 people
- Sponsor
- Assiut University
Adolescent Idiopathic Scoliosis, Juvenile Idiopathic Scoliosis
IV Methadone Vs EXPAREL Erector Spinae Plane Blockade in Pediatric Subjects Undergoing Idiopathic Scoliosis Correction
The goal of this pilot study is to assess the feasibility of conducting a randomized controlled trial at a single institution comparing erector spinae plane blockade (ESPB) with liposomal bupivacaine (LB, Exparel) to intravenous…
- Trial name
- AIMS (NCT05730920)
- Testing
- Methadone, Liposomal bupivacaine (LB, Exparel)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Dr. Casey Stondell, MD