Clinical trials: Rhabdomyolysis
Rhabdomyolysis Linked to a Hereditary Disease of Metabolism
Evaluate the Effort Test as a Therapeutic Monitoring Tool in Acute Rhabdomyolyses
The prognosis of rhabdomyolyses related to hereditary diseases of metabolism is poor and treatments are only symptomatic. Rhabdomyolysis outbreaks are frequently precipitated by fever and fasting. They are unpredictable.
- Trial name
- EFFORHAB (NCT03802279)
- Testing
- Effort test, Functional tests on fibroblasts
- Where
- France
- Volunteers
- 27 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Rhabdomyolysis
Lactoferrin Effect on Kidney and Heart of Rhabdomyolysis Rats
This study focuses on detecting the possible beneficial effect of Lactoferrin (Lf) administration on the kidney and the heart of glycerol-induced rhabdomyolysis (RM) in rats and its relation to ferroptosis and AMPK/Nrf2/ HO-1…
- Trial name
- NCT06491394
- Testing
- Lactoferrin, iron, MDA, TAC, and GSH
- Where
- Egypt
- Volunteers
- 24 people
- Sponsor
- Aswan University Hospital
Rhabdomyolysis, Myoglobinuria
Incidence of Rhabdomyolysis Among Patients Admitted With Jimsonweed Ingestions
Retrospective chart review to determine the presence of rhabdomyolysis among patients admitted to CHMCA from 1997-2007 with Jimsonweed ingestions and to define possible risk factors predisposing patients to the developement of…
- Conditions
- Rhabdomyolysis, Myoglobinuria, Hemoglobinuria
- Trial name
- NCT00592657
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- Akron Children's Hospital
Septic Shock, Acute Respiratory Distress Syndrome
CytOSorb TreatMent Of Critically Ill PatientS Registry
Registry intended to provide a data repository and reporting infrastructure for the surveillance of CytoSorb device use in real-world critical care settings, and to serve as an objective, comprehensive, and scientifically-based…
- Conditions
- Septic Shock, Acute Respiratory Distress Syndrome, Trauma, Rhabdomyolysis
- Trial name
- COSMOS (NCT05146336)
- Testing
- CytoSorb
- Where
- 28 sites in Austria, Germany and 4 more
- Volunteers
- 3,000 people
- Sponsor
- CytoSorbents, Inc
Acute Compartment Syndrome, Tibia Fracture
Biomarkers in the Diagnosis of Acute Compartment Syndrome
This prospective multinational, multicentre cohort study aims to investigate the hypothesis that biomarkers of muscle cell damage can predict acute compartment syndrome in patients with tibial fractures.
- Trial name
- BioFACTS (NCT04674592)
- Testing
- Blood samples and biopsies
- Where
- Sweden
- Volunteers
- 250 people
- Sponsor
- University Hospital, Linkoeping
Rhabdomyolysis, Myopathy
Study of the Causes of the Breakdown of Muscle Fibers in Hospitalized Patients
1. Analyze the various causes of breakdown of muscle fibers in hospitalized patients. 2. Analyze the characteristics of these patients in Taiwan (including the drugs history, risk factors and the incidence of complications).
- Conditions
- Rhabdomyolysis, Myopathy, Acute Renal Failure, Neuroleptic Malignant Syndrome
- Trial name
- NCT01022450
- Where
- Taiwan
- Volunteers
- 2,500 people
- Sponsor
- National Taiwan University Hospital
Lipin-1 Deficiency
International Multicenter Study on Lipin-1 Deficiency
LIPIN1 is an international registry that allows the collection of data on the follow-up, management and treatment of patients with Lipin-1 deficiency.
- Trial name
- LIPIN1 (NCT05564520)
- Where
- France
- Volunteers
- 12 people
- Sponsor
- Imagine Institute
Rhabdomyolysis
RhabdomYolyse in Intensive caRe
Analysis of the outcome of patients < 18 years old, treated in an intensive care unit for severe rhabdomyolysis, regardless of etiology (renal failure rate, death rate, organ replacement rate)
- Trial name
- RYR (NCT06101680)
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Central Hospital, Nancy, France
Rhabdomyolysis
Support for the Rhabdomyolysis in an Emergency Department
Rhabdomyolysis is a common condition in the UAA. Support is heterogeneous, it is in most cases a mass hyperhydration. The idea is to initially with an EPP simultaneously screened for the most affected by this disease and…
- Trial name
- RHABDURGENCE (NCT02896517)
- Where
- France
- Sponsor
- Fondation Hôpital Saint-Joseph
Rhabdomyolysis
Pediatric Rhabdomyolysis in the Pediatric Intensive Care Unit: A Retrospective Cohort Study
This retrospective observational cohort study aims to evaluate the clinical characteristics, causes, intensive care management, and outcomes of pediatric patients with rhabdomyolysis admitted to the Pediatric Intensive Care Unit…
- Trial name
- NCT07851987
- Where
- Germany
- Volunteers
- 55 people
- Sponsor
- Hannover Medical School
LIPIN1 Deficiency
Acute Rhabdomyolysis and Muscle Pain Associated With Mutations in the LPIN1 Gene - A Retrospective Study Describing the Safety and Efficacy of Hydroxychloroquine Sulfate Given on a Compassionate Basis to Patients Suffering From Lipin-1 Deficiency
Lipin-1 deficiencies are responsible for severe rhabdomyolysis and muscle pain in childhood. A specific treatment does not exist.
- Trial name
- LIPIN-1-METAB (NCT04007562)
- Testing
- Hydroxychloroquine Sulfate
- Where
- France
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Rhabdomyolysis
Exercise-induced Collective Rhabdomyolysis
Rhabdomyolysis, which is a characteristic occurrence in associated with muscle cell necrosis, develops due to various causes.The investigators herein report a rare case of collective rhabdomyolysis after high intensity resistance…
- Trial name
- NCT03737513
- Where
- China
- Volunteers
- 35 people
- Sponsor
- Haitao Tu
Acute Kidney Injury, Crush Injury
The Effects of Dexmedetomidine and Remifentanil on Kidney Injury After Muscle Compression Injury in Rats
The goal of this interventional preclinical study is to evaluate the potential protective effects of two intravenous anesthetic agents-dexmedetomidine and remifentanil-on kidney function in the context of muscle crush injury…
- Conditions
- Acute Kidney Injury, Crush Injury, Rhabdomyolysis
- Trial name
- NCT07094165
- Testing
- Dexmedetomidine, Remifentanil, Laparotomy
- Where
- Turkey (Türkiye)
- Volunteers
- 28 people
- Sponsor
- Ankara City Hospital Bilkent
Rhabdomyolysis
Dexamethasone Use in Pediatric Rhabdomyolysis Patients in Addition to Standard Protocols
There is a significant unmet need for optimized treatment in rhabdomyolysis. There are few prospective interventional studies on treatment for rhabdomyolysis, a condition which affects diverse and underrepresented populations at…
- Trial name
- NCT06429982
- Testing
- Dexamethasone
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Children's National Research Institute