Clinical trials: Proliferative Diabetic Retinopathy
Proliferative Diabetic Retinopathy
Comparison of Small-gauge Vitrectomy and Conventional Vitrectomy for Proliferative Diabetic Retinopathy
Surgical outcome of vitreous surgery for proliferative diabetic retinopathy (PDR) with conventional 20, 23, and 25-gauge vitrectomy were compared.
- Trial name
- NCT01758757
- Testing
- Vitrectomy
- Where
- Japan
- Volunteers
- 347 people
- Sponsor
- Kyorin University
Diabetes Mellitus, Type 2
Evaluation of Macular Structural and Functional Function Following Extensive Retinal Laser Therapy in Patients With Proliferative Diabetic Retinopathy
The present study is a semi-experimental clinical trial that 20 patients (40 eyes) with PDR underwent PRP with ARC with a spot number of 1,200 to 1,500 per eye and spot size 500 micron with a duration of 200 ms.
- Trial name
- NCT04436900
- Testing
- Panretinal Photocoagulation (PRP)
- Where
- Iran
- Volunteers
- 20 people
- Sponsor
- Baqiyatallah Medical Sciences University
Proliferative Diabetic Retinopathy
Analgesic Effect of Etoricoxib (ARCOXIA®) 120MG During Retinal Laser Photocoagulation
The study wants to show if the medication etoricoxib 120 mg have reduces the patients pain during the laser photocoagulation, for diabetic retinopathy.
- Trial name
- NCT00529594
- Testing
- Etoricoxib (Treatment Group)
- Where
- Brazil
- Volunteers
- 44 people
- Sponsor
- University of Sao Paulo
Retinal Detachment
Internal Limiting Membrane Flaps for Coexistent Macular Hole and Retinal Detachment
Purpose: To evaluate the logical surgical approaches in closing macular holes in eyes of proliferative diabetic retinopathy with retinal detachment
- Trial name
- ILMFCMHRDPDR (NCT03618498)
- Testing
- ILM flaps insertion techniques or free ILM flaps.
- Where
- Taiwan
- Volunteers
- 10 people
- Sponsor
- Changhua Christian Hospital
Severe Nonproliferative, Proliferative Diabetic Retinopathy
Intravitreal Bevacizumab for Diabetic Retinopathy
Background: to evaluate the 3-month efficacy of a single dose of intravitreal bevacizumab on the progression of severe non proliferative diabetic retinopathy, proliferative diabetic retinopathy and active photocoagulated diabetic…
- Conditions
- Severe Nonproliferative, Proliferative Diabetic Retinopathy, Active Photocoagulated Diabetic Retinopathy
- Trial name
- NCT00600262
- Testing
- intravitreal bevacizumab
- Where
- Mexico
- Sponsor
- Asociación para Evitar la Ceguera en México
PDR
A Single-Center Trial of Intravitreous Injections of Macugen (Pegaptanib Sodium) Given at Least 7 Days Before Vitrectomy Secondary To Tractional Retinal Detachment in Proliferative Diabetic Retinopathy
Primary objective of this trial will be to evaluate the safety and efficacy of intravitreal injections of Macugen (pegaptanib sodium) when given at least 7-14 days prior to vitrectomy in subjects with tractional retinal…
- Trial name
- NCT01487070
- Testing
- Macugen (Pegaptanib Sodium)
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Retina Institute of Hawaii
Diabetic Proliferative Retinopathy, Vascular Vein Oclussion
Multifocal Electrophysiologic Findings After Intravitreal Bevacizumab(Avastin)Treatment
Purpose: Determine the short-term safety of intravitreal bevacizumab by multifocal electroretinography (mf-ERG). Methods: 120 eyes with choroidal neovascularization, proliferative diabetic retinopathy and retinal vein occlusion…
- Conditions
- Diabetic Proliferative Retinopathy, Vascular Vein Oclussion, Choroidal Neovascularization
- Trial name
- NCT00417833
- Testing
- Intravitreal Bevacizumab
- Sponsor
- Asociación para Evitar la Ceguera en México
Proliferative Diabetic Retinopathy, Diabetic Traction Retinal Detachment
Prospective Randomized Controlled Study of Intravitreal Injection of Bevacizumab for Proliferative Diabetic Retinopathy
We hypothesized that to reduce the adverse effects of intravitreal bevacizumab on ocular tissue and whole body, intravitreal injection of a low concentration of bevacizumab and conducting vitrectomy shortly after the injection is…
- Conditions
- Proliferative Diabetic Retinopathy, Diabetic Traction Retinal Detachment, Vitreous Hemorrhage
- Trial name
- NCT01854593
- Testing
- Bevacizumab, Vitrectomy
- Where
- Japan
- Volunteers
- 69 people
- Sponsor
- Nihon University
Proliferative Diabetic Retinopathy, Vitrectomy
Observation of the Efficacy of Different Vitrectomy Systems to Treat Proliferative Diabetic Retinopathy
In recent years, vitrectomy has moved toward a minimally invasive vitrectomy surgery (MIV) system, which could effectively reduce the occurrence of operation complications, while reducing the time of post-operation recovery.
- Trial name
- NCT05446948
- Testing
- beveled 27G+ vitrectomy system, standard 25G+ vitrectomy system
- Where
- China
- Volunteers
- 52 people
- Sponsor
- Tianjin Medical University Eye Hospital
Diabetic Retinopathy
Intravitreal Bevacizumab for Management of Active Progressive Proliferative Diabetic Retinopathy (PDR)
To evaluate the effect of intravitreal bevacizumab on the course of diabetic retinopathy in cases with the signs of active progressive PDR
- Trial name
- NCT00370721
- Testing
- bevacizumab
- Where
- Iran
- Sponsor
- Shahid Beheshti University of Medical Sciences
Panretinal Photocoagulation
Effect of Argon Laser Panretinal Photocoagulation on Corneal Endothelial Cell Density .
This study investigates the effect of argon laser panretinal photocoagulation (PRP) on the corneal endothelial cell density (ECD) in patients with proliferative diabetic retinopathy (PDR) by comparing ECD measurements before and…
- Trial name
- NCT07157553
- Volunteers
- 45 people
- Sponsor
- Assiut University
Diabetic Retinopathy
Effect of Intravitreal Bevacizumab on Early Post-Vitrectomy Hemorrhage in Diabetic Patients
The purpose of this study is to determine whether bevacizumab 1-2 weeks before vitrectomy is effective in lowering the rate of early post-vitrectomy vitreous hemorrhage in diabetic patients.
- Trial name
- NCT00524875
- Testing
- Bevacizumab
- Where
- Iran
- Volunteers
- 80 people
- Sponsor
- Shahid Beheshti University of Medical Sciences
Non-Proliferative Diabetic Retinopathy
Intravitreal and Intracameral DEX in NPDR
To investigate the effects of intravitreal and intracameral injection of dexamethasone during cataract phacoemulsification in patients with mild to moderate non-proliferative diabetic retinopathy
- Trial name
- NCT06951087
- Testing
- Dexamethasone sodium phosphate
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Affiliated Hospital of Nantong University
Proliferative Diabetic Retinopathy
Compliance to Ophthalmic Follow-up Examinations and Surgical Outcome for Proliferative Diabetic Retinopathy
The relationship between the surgical outcome of vitreous surgery for proliferative diabetic retinopathy and the compliance to ophthalmic follow-up examinations was evaluated.
- Trial name
- NCT01307072
- Testing
- Vitrectomy
- Where
- Japan
- Volunteers
- 94 people
- Sponsor
- Kyorin University
Proliferative Diabetic Retinopathy
Efficacy of PreOperative Bevacizumab for Diabetic Eye Disease
Reports of the use of intravitreal bevacizumab (Avastin, Genentech) for the reduction of neovascularization in proliferative diabetic retinopathy have demonstrated significant regression in the number of new vessels.
- Trial name
- NCT01041690
- Testing
- Bevacizumab
- Where
- Egypt
- Volunteers
- 19 people
- Sponsor
- Cairo University
Proliferative Diabetic Retinopathy, Angiogenesis
Fractalkine, a CX3C Chemokine, Act as a Mediator of Ocular Angiogenesis
Fractalkine (FKN) is a chemoattractant and adhesion molecule for leukocytes. Angiogenic effect of FKN also has been reported. We investigate FKN-mediated angiogenesis in ocular angiogenic disorders.
- Trial name
- NCT00728598
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- National Taiwan University Hospital
Proliferative Diabetic Retinopathy
OCT and OCT-A Afer Diabetic Vitrectomy in PDR
Detection of any structural or vascular changes at the macula after Pars Plana Vitrectomy ( PPV ) in cases with complicated proliferative diabetic retinopathy ( PDR )
- Trial name
- NCT05938491
- Testing
- OCT and OCT-A
- Volunteers
- 30 people
- Sponsor
- Assiut University
Diabetic Retinopathy
Intravitreal Bevacizumab for Proliferative Diabetic Retinopathy
Recently, intravitreal bevacizumab (Avastin) injection has gained popularity as a potential treatment of intraocular neovascularization (CNV) associated with age related macular degeneration and diabetic retinopathy.
- Trial name
- NCT00423059
- Testing
- bevacizumab
- Where
- South Korea
- Volunteers
- 20 people
- Sponsor
- Yonsei University
Proliferative Diabetic Retinopathy
Intravitreal Ozurdex After Pars Plana Vitrectomy for Proliferative Diabetic Retinopathy
To evaluate if intravitreal Ozurdex can reduce the incidence of recurrent vitreous hemorrhage after primary pars plana vitrectomy (PPV) in patients with proliferative diabetic retinopathy (PDRP).
- Trial name
- NCT01478737
- Testing
- Intravitreal dexamethasone implant, Vitrectomy
- Where
- Sweden
- Volunteers
- 100 people
- Sponsor
- Anders Kvanta
Proliferative Diabetic Retinopathy
Surgical Outcomes for Proliferative Diabetic Retinopathy by Preoperative Glycemic Control and Renal Function
The surgical outcomes of 25-gauge vitrectomy for proliferative diabetic retinopathy has been evaluated by preoperative glycemic control and renal function
- Trial name
- NCT03522311
- Testing
- Vitrectomy
- Volunteers
- 251 people
- Sponsor
- Kyorin University