Clinical trials: Pregnant People
Birth Outcome, Adverse, Labor Long
How Long Can Labor Last? Person Centred Care During Labor to Increase Safety for Women and Newborn
"How long will my labor last" is a very common question for midwives who care for women during birth. To evaluate safe labor duration largely determines management and care during birth.
- Conditions
- Birth Outcome, Adverse, Labor Long, Labor Complication, Maternal Injury
- Trial name
- NCT06420453
- Where
- Sweden
- Volunteers
- 300,000 people
- Sponsor
- Karolinska Institutet
Impaired Glucose Tolerance, Hyperinsulinism
Effect of Meal Frequency on Glycemic Control of People at High Risk or Diagnosed With Diabetes
This study investigated any potential associations between two isocaloric diets with different meal frequency (3 meals versus 6 meals) and glycemic control in people at high diabetes risk (lean and overweight/obese women with…
- Conditions
- Impaired Glucose Tolerance, Hyperinsulinism, Poor Glycemic Control, Hyperglycemia
- Trial name
- NCT02248272
- Testing
- Isocaloric diet with 3 meals, Isocaloric diet with 6 meals
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Meropi Kontogianni
Intellectual Disability, Adolescent Development
Prevention Among Young People With Intellectual Disability
This study aims to evaluate an intervention using the Toolkit "Children - what does it involve?" and the "Real-Care-Baby" (RCB) simulator among students with intellectual disability (ID), using a cluster randomized trial design…
- Conditions
- Intellectual Disability, Adolescent Development, Young Adult
- Trial name
- NCT03348124
- Testing
- "Children - what does it involve?"
- Where
- Sweden
- Volunteers
- 59 people
- Sponsor
- Uppsala University
HIV Infections, Pregnancy Related
Adaptation of an Intervention Addressing Barriers to PrEP Use Among Pregnant Women in Zimbabwe
The purpose of this study is to develop a multi-level PrEP adherence and persistence intervention as an adaptation of the TENDAI ('grateful' in Shona) program, a problem-solving approach to reduce depression and increase HIV…
- Conditions
- HIV Infections, Pregnancy Related, Depression, Anxiety
- Trial name
- TENDAI4PrEP (NCT06226155)
- Testing
- TENDAI4PrEP, Enhanced treatment as usual
- Where
- Zimbabwe
- Volunteers
- 165 people
- Sponsor
- Massachusetts General Hospital
Attention-Deficit/Hyperactivity Disorder (ADHD), Autism Spectrum Disorder
Home Play-based Intervention for Parents and Infants
The goal of this clinical trial is to learn whether a 12-week home-based intervention (Sociometric Play-based Remediation of Individual Neurodevelopmental Trajectories (SPRINT)) helps support parenting and the development of…
- Conditions
- Attention-Deficit/Hyperactivity Disorder (ADHD), Autism Spectrum Disorder, Premature Birth, Global Developmental Delay
- Trial name
- SPRINT (NCT07716072)
- Testing
- SPRINT Intervention, Waitlist Protocol
- Where
- Singapore
- Volunteers
- 120 people
- Sponsor
- Nanyang Technological University
Renal Cell Carcinoma
Survey of Cabozantinib Used To Treat People With Renal Cell Carcinoma
This study is a survey in Japan of Cabozantinib tablets used to treat people with a type of kidney cancer called renal cell carcinoma.
- Trial name
- NCT04804813
- Testing
- Cabozantinib
- Where
- Japan
- Volunteers
- 388 people
- Sponsor
- Takeda
Infant Development, Neonatal Intensive Care Unit
Individual Structured Therapy in Early Premature Infants at the Neonatal Intensive Care Unit
In this study, investigators aimed to apply an individual structured therapy protocol within the framework of neurodevelopmental therapy principles in early premature infants hospitalized in the neonatal intensive care unit and…
- Conditions
- Infant Development, Neonatal Intensive Care Unit, INDIVIDUALIZED THERAPY
- Trial name
- NCT06648213
- Testing
- Physiotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Infant, Premature, Diseases, Bronchopulmonary Dysplasia
Appropriate Oxygen Levels for Extremely Preterm Infants: a Prospective Meta-analysis
The primary question to be addressed by this study is: compared with a functional oxygen saturation level (SpO2) of 91-95%, does targeting SpO2 85-89% in extremely preterm infants from birth or soon after, result in a difference…
- Conditions
- Infant, Premature, Diseases, Bronchopulmonary Dysplasia, Retinopathy of Prematurity, Infant, Newborn, Diseases
- Trial name
- NeOProM (NCT01124331)
- Testing
- Higher oxygen saturation target range (91%-95%), Lower oxygen saturation (85%-89%)
- Where
- 9 sites in Australia
- Volunteers
- 4,965 people
- Sponsor
- University of Sydney
Pelvic Girdle Pain, Symphysio Pubic Dysfunction
Trial for the Treatment of Pelvic and Back Pain in Pregnancy
The investigators aim to conduct a prospective open label randomized controlled trial to test the hypothesis that following initial assessment by a physiotherapist, group care exercise class is as effective in reducing pain as…
- Trial name
- GRIP (NCT00830934)
- Testing
- Individual care, group care
- Where
- Ireland
- Volunteers
- 226 people
- Sponsor
- University College Cork
Urinary Incontinence
Pilot Study - Patient Education and Pelvic Strength Exercises in Elderly Women With Incontinence.
It will be investigate if women with a diaper grant in Aalborg Municipality can reduce diaper size and thus costs for diapers in the municipality through meetings with a incontinence nurse and pelvic floor exercises.
- Trial name
- NCT03862326
- Testing
- Exercise
- Where
- Denmark
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- University College of Northern Denmark
HIV Infections, Hepatitis B
Antiretroviral Pregnancy Registry (APR): Multi-sponsor Registry to Detect Any Major Teratogenic Effect Involving Any of the Registry Drugs When Administered to Pregnant People.
The purpose of the Antiretroviral Pregnancy Registry (Registry) is to detect any major teratogenic effect involving any of the Registry drugs when administered to pregnant people.
- Trial name
- APR (NCT00404989)
- Where
- United States
- Volunteers
- 24,258 people
- Sponsor
- Syneos Health
Cystic Fibrosis (CF), Chronic Kidney Disease(CKD)
Kidney Function in People With Cystic Fibrosis in the Era of HEMT
The purpose of this study is to find out what causes kidney disease in people with CF. The investigators will study biomarkers in the blood and urine that can either predict who is at risk or detect kidney damage early before it…
- Conditions
- Cystic Fibrosis (CF), Chronic Kidney Disease(CKD), Acute Kidney Injury
- Trial name
- NCT06595420
- Where
- 3 sites in United States
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Wilms Tumor, Rhabdoid Tumor
A Study of Selinexor in People With Wilms Tumors and Other Solid Tumors
The purpose of this study is to find out whether selinexor is an effective treatment for people who have a relapsed/refractory Wilms tumor, rhabdoid tumor, MPNST, BCOR-driven sarcoma, or another solid tumor that makes a higher…
- Conditions
- Wilms Tumor, Rhabdoid Tumor, Malignant Peripheral Nerve Sheath Tumors, MPNST
- Trial name
- NCT05985161
- Testing
- Selinexor
- Where
- 16 sites in United States
- Volunteers
- 45 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Extrahepatic Bile Duct Cancer, Gallbladder Cancer
Anonymous Testing of Pathology Specimens for BRCA Mutations in Ashkenazi Jewish Individuals Who Have Cancer
The intent of the proposed study is to describe the prevalence of the most common recurring mutations in BRCA1 and BRCA2, blmAsh , and the A636P MSH2 mutation among Ashkenazi Jewish individuals with a variety of cancer diagnoses.
- Conditions
- Extrahepatic Bile Duct Cancer, Gallbladder Cancer, Gastric Cancer, Lung Cancer
- Trial name
- NCT00588263
- Where
- United States
- Sponsor
- Memorial Sloan Kettering Cancer Center
Adrenal Hyperplasia, Polycystic Ovarian Syndrome
Adrenal Hyperplasia Among Young People With PCOS
Background: Polycystic ovarian syndrome (PCOS) is a group of disorders related to problems with the secretion of certain hormones, which can lead to reproductive and other issues in women.
- Conditions
- Adrenal Hyperplasia, Polycystic Ovarian Syndrome, Oligomenorrhea, Obesity
- Trial name
- NCT01313455
- Where
- United States
- Volunteers
- 96 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Medication Abortion, Health Knowledge Attitudes and Practice
Patient Agreement Form and Medication Abortion Knowledge
This study evaluates whether exposure to the U.S. Food and Drug Administration (FDA)-required Patient Agreement Form (PAF) for mifepristone improves patient knowledge about medication abortion.
- Conditions
- Medication Abortion, Health Knowledge Attitudes and Practice, Pregnant People
- Trial name
- NCT07604675
- Testing
- Patient Agreement Form (PAF)
- Where
- 5 sites in United States
- Volunteers
- 637 people
- Sponsor
- University of California, San Francisco
HIV Infections, Kidney Disease
Kidney and Liver Transplantation in People With HIV
With improved anti-HIV drug therapy, HIV infected patients are now living longer. These patients are at risk for liver and kidney failure and may need organ transplants.
- Conditions
- HIV Infections, Kidney Disease, Liver Disease
- Trial name
- NCT00074386
- Where
- 21 sites in United States
- Volunteers
- 275 people
- Sponsor
- University of California, San Francisco
Autosomal Dominant Polycystic Kidney Disease (ADPKD
Hypertension in Children and Young People at Risk of Autosomal Dominant Polycystic Kidney Disease
The goal of this project is to measure the prevalence of Autosomal Dominant Polycystic Kidney Disease (ADPKD) and hypertension in the general population of children and young people at risk of ADPKD, using magnetic resonance…
- Trial name
- HIYA-PKD (NCT07260071)
- Where
- United Kingdom
- Volunteers
- 200 people
- Sponsor
- King's College London
Persons With Psychiatric Disorders
Perinatal Peer Support for Veterans With Serious Mental Illness
Veterans with serious mental illness (SMI) are at high risk of exacerbation of mental illness in pregnancy and postpartum, with consequences including poor pregnancy outcomes, decreased functioning, and impaired child…
- Trial name
- NCT07362576
- Testing
- Perinatal peer support
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- VA Office of Research and Development
Hypertension, Morality
Mortality Outcome of Controlled Hypertension
This review focuses on the assumption of mortality outcome of participants remaining label hypertension care is adequately managed when pressure targets are met with both qualitative and quantitaive method.
- Conditions
- Hypertension, Morality, Death, Pre-Eclampsia
- Trial name
- MOCH1 (NCT07187596)
- Where
- Thailand
- Volunteers
- 2,547 people
- Sponsor
- DejthidaNathaphong