Clinical trials: Pregnancy, High-Risk
High-risk Pregnancy, Hospitalization
LLM-Generated Medical Summaries During Hospitalization to Improve Patient Activation in High-Risk Pregnancies
The goal of this clinical trial is to learn if AI-generated medical summaries help hospitalized pregnant participants better understand and actively participate in their own care.
- Conditions
- High-risk Pregnancy, Hospitalization, Patient Activation, Artificial Intelligence (AI)
- Trial name
- NCT07823517
- Testing
- LLM-Generated Medical Summaries
- Where
- Israel
- Volunteers
- 200 people
- Sponsor
- Sheba Medical Center
High Risk Pregnancy
Antenatal High-Risk Pregnancy Intervention Bundle in Rural Nepal
The proposed study will assess and implement a comprehensive antenatal HRP screening and telehealth follow-up program in rural Nepal. The main questions it aims to answer are: 1.
- Trial name
- NCT07717619
- Testing
- High Risk Pregnancy Bundle
- Where
- Nepal
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Diabetes Mellitus, Type 2, Preterm Birth
Glycemic Control After Antenatal Corticosteroids in Women With Pregestational and Gestational Diabetes
There is a fundamental gap in understanding the maternal and neonatal effects of antenatal corticosteroid (ACS) administration in women with threatened preterm birth (PTB) who have diabetes.
- Conditions
- Diabetes Mellitus, Type 2, Preterm Birth, Pregnancy, High Risk, Diabetes, Gestational
- Trial name
- NCT04542148
- Testing
- Sliding Scale Insulin, Up-Titration of Home Insulin, Continuous Insulin Infusion
- Where
- 4 sites in United States
- Volunteers
- 120 people
- Sponsor
- University of Alabama at Birmingham
High Risk Pregnancy, Cesarean Section
Education of Pregnant Women With a Prenatal Indication for Cesarean Section Through Periodic Short Message Service (SMS) and Interactive Voice Response System (IVR) in Uganda
Women with antenatally identified indications for planned pre-labor cesarean delivery in low-resource settings frequently present in labor before their scheduled delivery, resulting in emergency cesarean delivery and increased…
- Trial name
- NCT07696325
- Testing
- SMS and Interactive Voice Response (IVR) Educational Intervention
- Where
- Uganda
- Volunteers
- 71 people
- Sponsor
- Massachusetts General Hospital
Pregnancy, High Risk
PRISMA Maternal and Newborn Health Study
Access to quality antenatal care (ANC) and postnatal care (PNC), including maternal, newborn, and infant services, is integral to reducing adverse pregnancy-related health outcomes and promoting positive birth experiences.
- Trial name
- PRiSMA-MNH (NCT05904145)
- Where
- 5 sites in Ghana, India and 3 more
- Volunteers
- 267,897 people, healthy volunteers welcome
- Sponsor
- George Washington University
Pregnancy, High-Risk Pregnancy
UCLA Perinatal Biospecimen Repository
The purpose of this investigator-initiated prospective observational cohort study is to establish the new UCLA Perinatal Biospecimen Repository (Perinatal Repository) for collection, storage, and distribution of the human data…
- Trial name
- NCT05035160
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Yalda Afshar, MD, PhD
High-risk Pregnancy, Breast Feeding
Effect of Hypnobreastfeeding Education in High-Risk Pregnant Women
It is thought that hypnobreastfeeding training given to high-risk pregnant women will reduce anxiety levels, increase lactation, encourage breastfeeding, reduce the perception of insufficient milk, and facilitate adaptation to…
- Trial name
- NCT07281339
- Testing
- Hypnobreastfeeding Education
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Amasya University
Pregnancy, High Risk, Child Development
Nurse Family Partnership for Women With Previous Live Births
The goal of this clinical trial is to test the Nurse Family Partnership (NFP) in mothers with previous live births (multiparous or multip individuals).
- Conditions
- Pregnancy, High Risk, Child Development, Post Partum Depression
- Trial name
- NCT05887115
- Testing
- Nurse Family Partnership
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Pregnancy Related, Pregnancy Complications
Relugolix Pregnancy Registry: An Observational Study of the Safety of Relugolix-Containing Therapy Exposure in Pregnant Women and Their Offspring
The Relugolix Pregnancy Registry is a prospective, observational cohort study designed to evaluate the association between relugolix-containing therapy exposure during pregnancy and subsequent maternal, fetal, and infant…
- Conditions
- Pregnancy Related, Pregnancy Complications, Pregnancy, High Risk
- Trial name
- NCT05739123
- Testing
- Relugolix-Containing Product
- Where
- United States
- Volunteers
- 728 people
- Sponsor
- Sumitomo Pharma Switzerland GmbH
Pregnancy, High Risk
Validation of a Non-invasive Hemoglobin Measurement Device in Pregnancy and Postpartum in Kenya, Pakistan, and Zambia
Accurate, precise, and comparable hemoglobin measurements is of great importance, both for clinical value in diagnosing anemia and ensuring pregnant women receive appropriate treatment.
- Trial name
- NCT05656352
- Testing
- Masimo Total Hemoglobin SpHb® Continuous Non-invasive Hemoglobin Monitoring Device, Complete Blood Count
- Where
- 4 sites in Kenya, Pakistan and 1 more
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- George Washington University
Angiogenesis, Fetal Weight
Multiple Micronutrients Supplementation on Angiogenesis and Vasculogenesis Factors, and Fetal Biometry
Multiple micronutrients play an important role during pregnancy, since the decidualization and implantation phases. It has an impact on placentation and remodeling of blood vessels.
- Conditions
- Angiogenesis, Fetal Weight, Pregnancy Related, Nutrient Element Deficiency
- Trial name
- NCT06929793
- Testing
- Multiple Micronutrients, Standard Antenatal Vitamin
- Where
- Indonesia
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Dr Cipto Mangunkusumo General Hospital
Pregnancy, Ectopic, Pregnancy, High Risk
Management of Pregnancies of Unknown Location (PUL)
In a randomized multicenter trial the investigators want to compare the ability of two hCG-based models in correctly classifying EPs as high risk among PULs and correctly classifying IUPs and failed PULs as low risk after two hCG…
- Conditions
- Pregnancy, Ectopic, Pregnancy, High Risk, Pregnancy Early
- Trial name
- NCT03461835
- Testing
- Risk classification of PUL by M4, Risk classification of PUL by NICE
- Where
- 3 sites in Sweden
- Volunteers
- 609 people
- Sponsor
- Göteborg University
Sickle Cell Disease, Pregnancy, High Risk
SCRIPT: Sickle Cell Risk in Pregnancy Tool
Sickle Cell Disease (SCD), common in persons of Black ancestry, affects the shape of hemoglobin, the oxygen-carrying part of red blood cells (RBC).
- Conditions
- Sickle Cell Disease, Pregnancy, High Risk, Pregnancy Complications
- Trial name
- SCRIPT (NCT06529042)
- Testing
- Non-Interventional
- Where
- 3 sites in United States, Canada
- Volunteers
- 1,000 people
- Sponsor
- Mount Sinai Hospital, Canada
Family, Pregnancy, High Risk
The Effectiveness of MInding the Baby in a Danish Community Sample
Minding the Baby is an intensive and preventive home-visiting programme that helps vulnerable or high risk mothers. MTB is delivered by an interdisciplinary team.
- Trial name
- MTB (NCT03495895)
- Testing
- Minding the Baby, Usual Care
- Where
- Denmark
- Volunteers
- 256 people
- Sponsor
- VIVE - The Danish Center for Social Science Research
Pregnancy Complications, Pregnancy, High Risk
Defining, Recognising and Escalating Maternal Early Deterioration (DREaMED)
Every year more than 700,000 women give birth in the United Kingdom. Of these at least 8700 nearly die - called a "near-miss", and 70 die. Many more women suffer harm, often with effects lasting for life.
- Trial name
- DREaMED (NCT06560931)
- Where
- United Kingdom
- Volunteers
- 459,160 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Screening for Hyperglycemia in First Trimester in High and Low Risk Pregnancy
Screening For First Trimester's Hyperglycemia in High and Low Risk Pregnancy
Glucose intolerance is the commonest medical disorder complicating pregnancy. Hyperglycemia increases the risk of delivering a large for gestational age newborn (LGA) and related complications such as operative delivery, birth…
- Trial name
- NCT06064552
- Testing
- blood sugar
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Sohag University
Preterm Premature Rupture of the Membranes, Pregnancy Complications
Ambulation for Latency During Expectant Management of PPROM
Ambulation in pregnancy has been proposed to decrease stress and anxiety, increasing preterm birth. Whether ambulation is causally related to latency is unknown.
- Conditions
- Preterm Premature Rupture of the Membranes, Pregnancy Complications, Pregnancy, High Risk
- Trial name
- AMBLE (NCT04230967)
- Testing
- Ambulation Group, Routine Care
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- The University of Texas Health Science Center, Houston
Stress, Pregnancy, High Risk
The Effect of Mindfulness-Based Stress Reduction Program (MBSR) in Risky Pregnants
Risky pregnant women need various physical and mental health needs, they need to be informed and supported by health personnel. Mindfulness is a non-judgmental and accepting focus of one's attention on what is happening right…
- Trial name
- NCT05317065
- Testing
- Mindfullness Based Stress Reduction (MBSR) intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 94 people
- Sponsor
- Amasya University
Gestational Diabetes, Pregnancy, High Risk
The Effect of Home Midwifery Care Given to Pregnant Women Diagnosed With Gestational Diabetes on Attitudes and Self-Care
Since gestational diabetes carries the risk of serious complications for the mother and fetus, it is very important to follow up the pregnancy carefully and consciously.
- Trial name
- NCT05670769
- Testing
- Education
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Cukurova University
Pregnancy, High Risk, Contraception
Use of an Educational Multimedia Tool Versus Routine Care for the Uptake of Postpartum LARC in High-Risk Pregnancies
The purpose of the study is to evaluate if the implementation of a multimedia based educational tool and regular reminders with shared decision-making will increase the rate of LARC uptake and retention in high risk pregnancy…
- Trial name
- SUSTAIN (NCT04291040)
- Testing
- Decision Aid, Routine Care
- Where
- United States
- Volunteers
- 380 people
- Sponsor
- The University of Texas Health Science Center, Houston