Clinical trials: Postoperative Mortality
Postoperative Mortality
Evaluation of Co-morbidity Scales
Peri-operative mortality depends on the patient's co-morbidities. ASA Physical Status (American Society of Anesthesiology) is the most commonly scale to assess this parameter and has yet been repeatedly criticized in the past for…
- Trial name
- Ko-MoSkau (NCT01810133)
- Where
- Germany
- Volunteers
- 230,034 people
- Sponsor
- Charite University, Berlin, Germany
Congenital Heart Surgery, Congenital Heart Defects
Death Following Congenital Heart Surgery
The purpose of this study is to elucidate the patterns of death following congenital heart surgery.
- Trial name
- NCT00215072
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Children's Healthcare of Atlanta
External Causes of Morbidity and Mortality
Comparative Analysis of APACHE II and P-POSSUM
To compare APACHE II and P-POSSUM scoring system in emergency laparotomy.
- Trial name
- NCT02471612
- Where
- India
- Volunteers
- 159 people
- Sponsor
- Tata Main Hospital
Postoperative Complications
Derivation and Validation of the Extended Care (Ex-Care) Model II
The goal of this study is to develop a novel surgical risk stratification tool designed to adults operated in Brazil. The main question it aims to answer is: •Is the Extended Care (Ex-Care) II model a good tool to assess the risk…
- Trial name
- Ex-CareII (NCT05796024)
- Where
- Brazil
- Volunteers
- 107,372 people, healthy volunteers welcome
- Sponsor
- Hospital de Clinicas de Porto Alegre
Colorectal Neoplasms, Peritoneal Neoplasms
PIPAC for Peritoneal Metastases of Colorectal Cancer
This is multicentre, open-label, single-arm phase II study that investigates the feasibility, safety, tolerability, preliminary efficacy, costs, and pharmacokinetics or repetitive electrostatic pressurised intraperitoneal aerosol…
- Conditions
- Colorectal Neoplasms, Peritoneal Neoplasms, Appendiceal Neoplasms, Peritoneal Carcinomatosis
- Trial name
- CRC-PIPAC (NCT03246321)
- Testing
- repetitive ePIPAC-OX
- Where
- 2 sites in Netherlands
- Volunteers
- 20 people
- Sponsor
- Koen Rovers
Social Deprivation
Social Deprivation and Postoperative Mortality
Socioeconomic factors are associated with differences in health outcomes, but their impact on surgical patients is still not well understood, especially in low- and middle-income countries.
- Trial name
- NCT07621211
- Where
- 7 sites in Brazil
- Volunteers
- 45,000 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Aortic Coarctation, Retrospective Studies
Prevalence and Risk Factors for Hypertension and Recoarctation in Patients Operated for Aortic Coarctation
Multicenter Retrospective Study Over a 14-Year Period From 2010 to 2024
- Conditions
- Aortic Coarctation, Retrospective Studies, Cohort Studies, Hypertension
- Trial name
- PRECOHA (NCT07499609)
- Where
- France
- Volunteers
- 901 people
- Sponsor
- Institut Saint Pierre
Paediatric Surgery, Perioperative/Postoperative Complications
An African, Multi-centre Evaluation of Patient Care and Clinical Outcomes for Paediatric Patients Undergoing Surgery
Access to safe surgery is a basic human right. This is highlighted by the work of the Lancet Commission on Global Surgery. There is a large burden of surgical disease in the paediatric surgical population with a large unmet need.
- Conditions
- Paediatric Surgery, Perioperative/Postoperative Complications, Perioperative Outcomes, Hospital Mortality
- Trial name
- ASOS-Paeds (NCT05061407)
- Where
- 2 sites in South Africa, Sudan
- Volunteers
- 8,625 people
- Sponsor
- University of KwaZulu
Postoperative Mortality and Morbidity
Circadian, Weekly and Seasonal Variability of Postoperative Mortality and Morbidity (Zirkadianest)
Mortality is subject to cyclic variability: circadian, weekly, and seasonal. This has been shown for different populations, different diseases and in different countries, but not for surgical patients.
- Trial name
- NCT01903382
- Where
- Germany
- Volunteers
- 247,506 people
- Sponsor
- Charite University, Berlin, Germany
Femoral Neck Fracture
Interest of the OSA (Obstructive Sleep Apnea) Predictive Scores in the Prognosis of Postoperative Mortality of Femoral Neck Fractures
Interest of the four major OSA Predictive Scores (STOP-BANG, P-SAP, DES-OSA, OSA50) in the prognosis of postoperative mortality after femoral neck fracture.
- Trial name
- NCT02202122
- Testing
- OSA Scoring
- Where
- Belgium
- Sponsor
- Astes
Postoperative Complications, Morality
Postoperative Complications and Mortality With In-Hospital COVID-19 Omicron Infection After Surgery
Postoperative complications and mortality in patients with COVID-19 Omicron infection who have undergone specialized thoracic surgery are scarce.
- Trial name
- NCT06040606
- Testing
- In-Hospital COVID-19 Omicron Infection after surgery
- Where
- China
- Volunteers
- 119 people, healthy volunteers welcome
- Sponsor
- Tang-Du Hospital
Postoperative Complications, Patient Care Team
Extended Care in High-Risk Surgical Patient (EXCARE) Pathway in High-risk Surgical Population
High risk surgical patients are subject to complications that impact rehabilitation time, overall mortality and costs. This project proposes the creation of a post-surgery care pathway called Extended Care in High-Risk Surgical…
- Trial name
- EXCARE (NCT04187664)
- Testing
- Postoperative Monitoring, High-sensitivity cardiac troponin testing
- Where
- Brazil
- Volunteers
- 1,720 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Postoperative Wound Breakdown
Fascial Dehiscence and Mortality
Nationwide cohort study on short- and long-term mortality of patients with and without postoperative fascial dehiscence. The cohort will be comprised of patient undergoing open colonic resection for colonic cancer registered in…
- Trial name
- NCT03008265
- Testing
- Postoperative fascial dehiscence
- Where
- Denmark
- Volunteers
- 9,000 people
- Sponsor
- Kristian Kiim Jensen
Incidence of Surgical Site Infection, Short Intraoperative Briefings
Impact of Structured Communication in the OR on Surgical Site Infections: Prospective Observational Clinical Trial
Surgical site infection (SSI) is the most frequent complication in patients that undergo abdominal surgery. A previous prospective observational study in 167 patients undergoing elective open abdominal procedures showed that…
- Conditions
- Incidence of Surgical Site Infection, Short Intraoperative Briefings, Mortality, Shared Mental Model
- Trial name
- StOP (NCT02428179)
- Testing
- StOP? - Control group, StOP? - Intervention group
- Where
- Switzerland
- Volunteers
- 3,003 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Lung Cancer, Surgery--Complications
Assessment of the 90-day Mortality Risk Score After VATS Lobectomy
A five classes (A-E) aggregate risk score predicting 90-day mortality after video-assisted thoracoscopic lobectomy for lung cancer, including as independent factors male sex (3 points), carbon monoxide lung diffusion capacity…
- Conditions
- Lung Cancer, Surgery--Complications, Morality
- Trial name
- NCT04799509
- Testing
- VATS lobectomy
- Volunteers
- 2,209 people
- Sponsor
- Università degli Studi dell'Insubria
Patients Who Underwent Surgery for Congenital Heart Disease
Influence of Tidal Volume During Mechanical Ventilation on Postoperative Clinical Outcome in Pediatric Patients Undergoing Congenital Heart Surgery
High tidal volume during mechanical ventilation has been reported to increase mortality in patients with acute lung injury or acute respiratory distress syndrome.
- Trial name
- NCT02081274
- Testing
- Surgery for congenital heart disease
- Where
- South Korea
- Volunteers
- 1,000 people
- Sponsor
- Samsung Medical Center
Laparotomy, Laparotomy Surgery
Saudi Emergency Laparotomy Audit
The Saudi Emergency Laparotomy Audit (SELA) is a national, multicenter observational clinical audit designed to evaluate outcomes and quality of care for patients undergoing emergency laparotomy in Saudi Arabia.
- Conditions
- Laparotomy, Laparotomy Surgery, Emergency Treatment, Abdominal Diseases
- Trial name
- SELA (NCT07429929)
- Testing
- Emergency Laparotomy
- Where
- Saudi Arabia
- Volunteers
- 10,000 people
- Sponsor
- King Faisal Specialist Hospital & Research Center
Critical Illness, Postoperative Complications
General Surgery Patients at the Intensive Care Unit
Introduction: high-risk surgical patients in the intensive care unit (ICU) are a unique population that has yet to be carefully monitored.
- Trial name
- TraViII (NCT06731296)
- Testing
- Presence of a risk factor
- Where
- 2 sites in Colombia
- Volunteers
- 1,000 people
- Sponsor
- Hospital Departamental de Villavicencio
Pancreas Cancer, Periampullary Carcinoma
Role of Pre-operative CPET in Pancreatoduodenectomy
A clinical database has been prospectively maintained by the investigators, with details of pancreatic resections since January 2016.
- Trial name
- WHIPPLES (NCT06068452)
- Where
- United Kingdom
- Volunteers
- 113 people
- Sponsor
- East Lancashire Hospitals NHS Trust
Postoperative Complications, Complications of Surgical Procedures or Medical Care
Effects of Checklists in Surgical Care - a Study on Complications, Death and Quality of Patient Administrative Data
This project aims to produce a systematic review on present knowledge on effects of using safety checklists in medicine. Implementation of a checklist system throughout surgical care may reduce patient morbidity and mortality.
- Trial name
- NCT01872195
- Testing
- The comprehensive patient safety checklist system
- Where
- Norway
- Volunteers
- 21,000 people
- Sponsor
- Haukeland University Hospital