Clinical trials: Postoperative Infection
Pneumonia, Bloodstream Infection
Clinical Outcomes in Patients With Infection by Resistant Microorganism
The goal of this individual patient data meta-analysis is to estimate the attributed and the associated health burden related to bloodstream infections, pneumonia, skin and soft tissue infections, surgical site infections and…
- Conditions
- Pneumonia, Bloodstream Infection, Urinary Tract Infections, Skin Infection
- Trial name
- NCT05880069
- Testing
- Pathogen resistant phenotype
- Where
- Spain
- Volunteers
- 5,000 people
- Sponsor
- Hospital Universitario Virgen Macarena
Postoperative Complications, COVID-19
Perioperative Complications Linked to COVID-19 History in Elective Cardiac Surgery Patients
A. Primary objective Identifying risk factors for peri-operative complications in patients who have had COVID-19. B. Secondary objectives Identifying peri-operative complications in patients who have had COVID-19.
- Trial name
- NCT05752162
- Where
- 2 sites in Romania
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Carol Davila University of Medicine and Pharmacy
Methicillin-resistant Staphylococcus Aureus Infection
Incidence and Relationship of Positive Preoperative Methicillin Resistant Staphylococcus Aureus (MRSA) Screens and Post-operative Infections
The purpose of this study is to evaluate the prevalence of pre-surgical patients who are MRSA carriers. From an evidence-based practice perspective, findings from this study can be considered in the evaluation of the hospital SOP…
- Trial name
- MRSA (NCT01028105)
- Testing
- Preoperative MRSA screening
- Where
- 2 sites in United States
- Volunteers
- 975 people
- Sponsor
- Inova Health Care Services
Surgical Site Infection
Effect of Triclosan-coated Suture on Superficial SSI
The abdominal closure with triclosan coated suture will reduce superficial surgical site infection.
- Trial name
- NCT02018289
- Testing
- Triclosan coated suture, No triclosan
- Where
- Spain
- Volunteers
- 106 people
- Sponsor
- Hospital General Universitario Elche
Surgical Site Infection
Disposable Versus Reusable DrApes and Gowns for Green OperatiNg Theatres
Multicentre non-inferiority cluster randomised trial testing Disposable versus Reusable drApes and Gowns for green OperatiNg theatres.
- Trial name
- DRAGON (NCT06164444)
- Testing
- Intervention: Reusable drapes and gowns, Comparator: Disposable (single-use) drapes and gowns
- Where
- Mexico
- Volunteers
- 26,800 people
- Sponsor
- University of Birmingham
Surgical Site Infection
Impact of Pre-surgical Nasal Bacterial Reduction on Postoperative Surgical Site Infections / Standard Care Change
Patients presenting in the Emergency Department or admitted to the hospital with displaced hip fractures who require hemiarthroplasty or open reduction internal fixation or with spinal instability/fractures in need of urgent…
- Trial name
- NCT01148030
- Testing
- 3M Skin and Nasal Antiseptic
- Where
- United States
- Volunteers
- 333 people
- Sponsor
- 3M
Abdominal Hernia
Light vs Heavy Weighted Mesh Repair in Primary Abdominal Hernia in Terms of Surgical Site Infection
This study compares the incidence of surgical site infections (SSI) in patients undergoing abdominal hernia repair using either light or heavy-weighted polypropylene mesh.
- Trial name
- NCT06644612
- Testing
- Light Weight Mesh, Heavy Weight Mesh
- Where
- Pakistan
- Volunteers
- 106 people
- Sponsor
- Khyber Medical University Peshawar
Infection Control, Surgical Site Infection
Early Recognition and Response to Increases in Surgical Site Infections Using Optimized Statistical Process Control Charts: The Early 2RIS Study
The purpose of this quality improvement study is to measure the effectiveness of surveillance using optimized statistical process control (SPC) methods and feedback on rates of surgical site infection (SSI) compared to…
- Trial name
- Early 2RIS (NCT03075813)
- Testing
- Intervention Cluster
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- Duke University
Staphylococcus Aureus, Orthopaedic Surgery
Preoperative Decolonization and Surgical Site Infections in Orthopaedic Surgery - 2 Year Outcome in Prosthetic Surgery
Surgical site infections in orthopaedic surgery are a major problem. Decolonization has been suggested to reduce infection rates.
- Conditions
- Staphylococcus Aureus, Orthopaedic Surgery, Surgical Site Infection, Prevention
- Trial name
- DECO-SSI (NCT03962907)
- Testing
- Chlorhexidine, Lifo-Scrub sol 4%®, 500ml, B. Braun, BACTROBAN® Nasal ong
- Where
- Switzerland
- Volunteers
- 1,318 people
- Sponsor
- Lindenhofgruppe AG
Surgical Site Infection, Complication,Postoperative
Study to Analyze the Surgical Site Infections in a Group of Patients Who Were Randomly Applied a Negative Pressure Therapy Dressing Versus Conventional Dressing
Surgical site complications generate a series of consequences that prolong hospital stay, increase interventions and procedures, and consequently considerably increase healthcare costs.
- Conditions
- Surgical Site Infection, Complication,Postoperative, Surgical Wound Infection, Surgical Complication
- Trial name
- NCT05455801
- Testing
- negative preassure wound therapy
- Where
- Spain
- Volunteers
- 271 people
- Sponsor
- Hospital Universitario Central de Asturias
Perforated Appendicitis
Surgical Site Infection in Perforated Appendicitis After Peritoneal Lavage With Super-oxidised Solution
This study is to evaluate the effectiveness of peritoneal lavage with super-oxidised solution in reducing surgical site infection after open surgery for perforated appendicitis.
- Trial name
- PLaSSo (NCT04512196)
- Testing
- Superoxidized Water, Normal Saline
- Where
- Malaysia
- Volunteers
- 102 people
- Sponsor
- Hospital Queen Elizabeth, Malaysia
Hyperoxia
Hyperoxygenation in Anesthetized Children
This study is aiming at assessing the effect of inspired oxygen fraction during general anesthesia on children's lung mechanics and volume.
- Trial name
- OXPED (NCT02384616)
- Testing
- Oxygen
- Where
- Switzerland
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Walid HABRE
Infection
Efficacy of Local Powder Prophylactics
Hypothesis: Directly applying antibiotic powder onto the site of surgery along with perioperative intravenous antibiotics, before closing the wound, is more effective than intravenously applied perioperative antibiotics alone in…
- Trial name
- NCT01372371
- Testing
- Vancomycin, Vancomycin and Gentamycin, Cefuroxime
- Where
- India
- Volunteers
- 1,844 people
- Sponsor
- Ganga Hospital
Anesthesia Morbidity, Sore Throat
Postoperative Sore Throat in the Pediatric Population.
Endotracheal tubes (ETT) and laryngeal mask airways (LMA) are devices used to help breathing whilst patients are asleep for surgery.
- Trial name
- POST (NCT03389776)
- Testing
- Anesthesia
- Where
- United Kingdom
- Volunteers
- 197 people
- Sponsor
- Istituto Giannina Gaslini
Surgical Site Infection
Subcutaneous Tissue Irrigation With Povidone Iodine in Decreasing the Rate of Surgical Site Infection Following Cesarean Section
This study aims to assess the efficacy of Povidone Iodine (Betadine®) irrigation of subcutaneous tissue prior to skin closure in reducing the incidence of surgical site infection after elective caesarean section and post…
- Trial name
- NCT03549702
- Testing
- Povidone iodine 1% solution
- Where
- Egypt
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Supracondylar Humerus Fracture, Post Operative Wound Infection
Antibiotics Usage in Pediatric Orthopaedic Percutaneous Surgery (APOPS)
The aim of this study is to determine if antibiotics affect the outcome after percutaneous surgery for pediatric supracondylar humerus fractures.
- Trial name
- NCT03261830
- Testing
- Cefazolin, Clindamycin, Saline
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- Sumit Gupta
Colon Rectal Cancer, Surgical Site Infection
Surveillance and Implementation of a Bundle of Care to Reduce Surgical Site Infection in Colorectal Surgery (CCR-VINCat)
The Nosocomial Infection Surveillance Program in Catalonia (VINCat) monitors surgical site infection (SSI) in elective colorectal surgery since 2007 in 55 public and private acute care hospitals.
- Trial name
- CCR-VINCat (NCT04496635)
- Testing
- Implementation of a bundle of care
- Where
- Spain
- Volunteers
- 60,000 people
- Sponsor
- Hospital de Granollers
Nephrolithiasis, Urinary Tract Infection (UTI)
Endourology Disease Group Excellence (EDGE) Consortium: Antibiotics (Abx) for Percutaneous Nephrolithotomy (PCNL) Part 2
This study will be a multi-institutional randomized clinical trial of a short course of pre-operative antibiotic prophylaxis in addition to perioperative antibiotics prior to undergoing percutaneous nephrolithotomy.
- Conditions
- Nephrolithiasis, Urinary Tract Infection (UTI), Sepsis
- Trial name
- PNLABXPART2 (NCT02829060)
- Testing
- Nitrofurantoin 100 MG, 7d, Gentamicin, 5mg/kg, Ampicillin 2g
- Where
- United States
- Volunteers
- 330 people
- Sponsor
- University of California, San Diego
Appendicitis, Acute, Appendectomy
Video-Based Grading of Intraoperative Adverse Events in Pediatric Laparoscopic Appendectomy
Acute appendicitis is the most common surgical emergency in children, and laparoscopic appendectomy is its standard treatment. Although intraoperative adverse events (iAEs) are recognized as an important determinant of surgical…
- Conditions
- Appendicitis, Acute, Appendectomy, Intraoperative Complications, Patient Safety
- Trial name
- PedAppy-iAE (NCT07794618)
- Testing
- Laparoscopic appendectomy
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Ahmet Burak Doğan, MD
COVID-19, Complication of Anesthesia
Association Between Post-covid Infection Status and Perioperative Morbidity: A Ambispective Cohort Study
With the knowledge of currently transmitted omicron variant being less virulent, over 90 percent of the Chinese population is fully vaccinated, and the Chinese health workers have sufficient experience treating the illness.
- Conditions
- COVID-19, Complication of Anesthesia, Complication of Surgical Procedure, Complication,Postoperative
- Trial name
- NCT05689840
- Testing
- Receiving inpatient surgical intervention
- Where
- China
- Volunteers
- 4,000 people
- Sponsor
- Peking Union Medical College Hospital