Clinical trials: Pollution; Exposure
Blood Pressure, Heart Rate Variability
The Cardiovascular Benefits of Reducing Personal Exposure to Air Pollution
Exposure to air pollution is an important risk factor for cardiovascular morbidity and mortality, and is associated with increased blood pressure, reduced heart rate variability, endothelial dysfunction and myocardial ischaemia.
- Trial name
- NCT00809432
- Testing
- Face mask (Dust Respirator), No Face mask
- Where
- China
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Edinburgh
Asthma in Children, Pollution; Exposure
AIM to Improve Asthma: Airflow Improvements During Meal-Prep
The investigators propose a pilot trial of kitchen ventilation in the homes of children using a youth engaged research strategy.
- Trial name
- AIM (NCT04464720)
- Testing
- Cooking Ventilation Intervention
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- University of California, Berkeley
Asthma
Asthma & Exposure to Peaks in Particulate Air Pollution
We are testing the following two hypotheses: 1) Peaks in hourly exposures to airborne particulate matter (PM) of outdoor origin will be more closely associated with acute asthmatic responses to particles than 24-hour average…
- Trial name
- NCT00013728
- Volunteers
- 24 people
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)
Acute Coronary Syndrome, Air Pollution
Air Pollution Exposure on Acute Coronary Syndrome in Two Cohorts of Industrial and Non-industrial Areas
Background: There is a lack of data on the effect of air pollution on acute coronary syndrome (ACS) in industrial and non-industrial areas.
- Trial name
- NCT04539925
- Testing
- Acute coronary syndrome
- Where
- 2 sites in Poland
- Volunteers
- 9,046 people
- Sponsor
- Medical University of Silesia
Asthma Acute, Respiratory
Children's Health, Respiratory Inflammation and Short-term Air Pollution
The goal of this study is to see if physical activity in high air pollution is worse than rest in high air pollution.
- Trial name
- CHERISH (NCT07431021)
- Testing
- science lesson, PE Lesson
- Where
- United Kingdom
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- Queen Mary University of London
Cognitive Function 1, Social, Cognitive Change
GReen And Healthy Schools
This project aims to investigate the health effects of making schools greener and more biodiverse. We will mainly focus on cognitive effects, well-being, and BMI.
- Conditions
- Cognitive Function 1, Social, Cognitive Change, Emotions, Weight, Body
- Trial name
- GRAS (NCT04898439)
- Testing
- greening of the school environment
- Where
- Belgium
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Hasselt University
Noise Exposure, Environmental Exposure
The Social Gradient of Urban Noise Pollution and Its Effect on Pediatric and Adult Health
The investigators pilot test an intervention to understand the spatial-temporal distribution of aggregated environmental noise exposure in Philadelphia and its impact on health.
- Conditions
- Noise Exposure, Environmental Exposure, Health Behavior
- Trial name
- NCT04822155
- Sponsor
- University of Pennsylvania
Water-Related Diseases, Enteric Pathogens
Rural Appalachia Pilot Water Treatment Trial
Consumption of unsafe drinking water is associated with a substantial burden of disease globally. In the USA, the burden of disease associated with consumption of contaminated drinking water from non-regulated private wells and…
- Conditions
- Water-Related Diseases, Enteric Pathogens, Exposure to Chemical Pollution
- Trial name
- NCT06120985
- Testing
- Countertop pitcher water filter
- Where
- 2 sites in United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Virginia Polytechnic Institute and State University
Tobacco Use, Pollution; Exposure
FRESHAIR4Life: Building the Case for Action
The goal of this observational study is to understand the burden and determinants of tobacco use and air pollution (AP) exposure among mid- to late adolescents in Greece, the Kyrgyz Republic, Pakistan, Romania, and Uganda.
- Conditions
- Tobacco Use, Pollution; Exposure, Non-communicable Disease
- Trial name
- NCT06074939
- Volunteers
- 1,750 people, healthy volunteers welcome
- Sponsor
- Leiden University Medical Center
Tobacco Smoke Pollution, Maternal Exposure During Pregnancy
Prenatal Tobacco Exposure and Newborn Outcomes: A Maternal Urinary Cotinine Study
Prenatal exposure to tobacco smoke, through either active maternal smoking or secondhand exposure, has been associated with impaired fetal oxygenation, metabolic stress, and adverse early neonatal outcomes.
- Conditions
- Tobacco Smoke Pollution, Maternal Exposure During Pregnancy, Infant, Newborn, Carbon Monoxide Poisoning
- Trial name
- NCT07201181
- Testing
- Maternal Urinary Cotinine Assessment
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Haseki Training and Research Hospital
Lung; Premature, Pollution; Exposure
Ultrafine Particles and Fetal Contamination
The objective of this study is to evaluate the transplacental passage of fine and ultrafine particles (nanoparticles) inhaled by the mother.
- Trial name
- FOETOPUF (NCT04068389)
- Testing
- Pulmonary Tissue Collection
- Volunteers
- 62 people
- Sponsor
- University Hospital, Bordeaux
Respiratory Tract Infections, Pneumonia
Randomised Exposure Study of Pollution Indoors and Respiratory Effects
The purpose of this study was to determine whether reduced exposure to indoor air pollution would reduce ALRI incidence in children <18 months of age.
- Trial name
- RESPIRE (NCT01047696)
- Testing
- Plancha
- Where
- Guatemala
- Volunteers
- 537 people, healthy volunteers welcome
- Sponsor
- University of California, Berkeley
Secondhand Exposure, Smoking Status
An Integrated Intervention to Reduce Secondhandsmoke in Children
This is a community essay to assess the effectiveness of a multi-level (individual, family, and school) school-based intervention to prevent the exposure to secondhand smoke (SHS) in a population of 1,734 schoolchildren (12-14…
- Trial name
- RESPIR·NET (NCT01881607)
- Testing
- RESPIRNET Program
- Where
- Spain
- Volunteers
- 1,779 people, healthy volunteers welcome
- Sponsor
- Institut Català d'Oncologia
Endothelial Dysfunction
Combustion Derived Air Pollution and Vascular Function
Air pollution is a major cause of cardiovascular morbidity and mortality. The components of air pollution responsible and the mechanisms through which they might mediate these harmful effects remain only partially understood.
- Trial name
- NCT00775099
- Testing
- Forearm Vascular Study, Badimon Chamber
- Where
- United Kingdom
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Edinburgh
Pneumonia, Pollution; Exposure
The Effect of Household Air Pollution on Lung Function Growth in Infants With Pneumonia in Sub-Saharan Africa
This study will evaluate the feasibility and acceptability of a household-based clean air intervention
- Conditions
- Pneumonia, Pollution; Exposure, Lung Function Decreased, Chronic Respiratory Disease
- Trial name
- PLUS2 (NCT05724082)
- Testing
- Clean Air Intervention
- Where
- Uganda
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Lung Disease, Cancer
Biomarkers of Benzene Exposure in Inner City Residents
This study compares air pollution exposures of residents in a South Baltimore community next to major industry with those in a comparison community with much less industry nearby.
- Trial name
- NCT00014963
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)
Women Who Gave Birth at Dijon and Besançon CHUs Between 2005 and 2009
Relationship Between Multi-exposure to Noise and Air Pollution and the Onset of Hypertension Disorders During Pregnancy
This retrospective study aimed to analyse the relationship between multi-exposure to noise and air pollution the onset of hypertension disorders during pregnancy It will be conducted in 2650 mothers who gave birth at Dijon or…
- Trial name
- HTA-BQuA (NCT03261245)
- Where
- 2 sites in France
- Volunteers
- 2,650 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire Dijon
Compliant Behavior, Diarrheal Disease
Rural China Electric Kettle Promotion Program
This study will evaluate the impact of a pilot Rural Electric Kettle Promotion Program offered to low-income households in rural Anhui Province, China.
- Conditions
- Compliant Behavior, Diarrheal Disease, Pollution; Exposure
- Trial name
- NCT03376152
- Testing
- Electric Kettle Promotion
- Where
- China
- Volunteers
- 6,000 people, healthy volunteers welcome
- Sponsor
- University of California, Berkeley
Exposure to Environmental Pollution, Adverse Effect of Unspecified General Anesthetic
Anesthetic Gas Leakage in Children During Tonsillectomy: a Comparison of Cuffed and Uncuffed Tracheal Tubes
Fires and operating room pollution may occur when anesthesia gases leak into the oropharynx during airway surgery. Investigators sought to measure the concentrations of anesthetic gases that leak into the mouth of children…
- Trial name
- NCT02725164
- Testing
- oxygen concentration, nitrous oxide concentration, carbon dioxide concentration
- Volunteers
- 31 people
- Sponsor
- State University of New York at Buffalo
Premature Birth, Respiratory Disease
Towards Life-Long Healthy Lungs: A Multidisciplinary Follow-up Framework for Preterm Infants
Approximately 8% of all births occur between 30-36 weeks of gestation ('moderate-late' prematurity). Respiratory tract infections (RTI) and wheezing illnesses disproportionally affect preterm infants resulting in a 1.5-2 fold…
- Conditions
- Premature Birth, Respiratory Disease, Respiratory Tract Infections, Preterm Birth
- Trial name
- LONG LOVE (NCT05618769)
- Testing
- LONG LOVE Framework
- Where
- Netherlands
- Volunteers
- 330 people
- Sponsor
- Franciscus Gasthuis