Clinical trials: Photobiomodulation Therapy
Oral Mucositis
Feasibility Study of a Protocol to Treat Pediatric Oral Mucositis by Low-level Laser Therapy
Low Level Laser Therapy has been used for a few years in some pediatric hospital centers for chemo- and radiotherapy-induced oral mucositis care. It may promote ulceration's healing, limits mucositis severity and associated pain.
- Trial name
- PEDIALASE (NCT02604329)
- Testing
- "Oncolase Digi" therapy laser diode
- Where
- France
- Volunteers
- 22 people
- Sponsor
- University Hospital, Toulouse
Diabetes Mellitus, Type 2
Evaluation of Macular Structural and Functional Function Following Extensive Retinal Laser Therapy in Patients With Proliferative Diabetic Retinopathy
The present study is a semi-experimental clinical trial that 20 patients (40 eyes) with PDR underwent PRP with ARC with a spot number of 1,200 to 1,500 per eye and spot size 500 micron with a duration of 200 ms.
- Trial name
- NCT04436900
- Testing
- Panretinal Photocoagulation (PRP)
- Where
- Iran
- Volunteers
- 20 people
- Sponsor
- Baqiyatallah Medical Sciences University
Low Level Laser Therapy
Effect of Low-level Laser Therapy on Orthodontic Tooth Movement
The objective of this trial is to investigate the effect of low-level laser therapy (LLLT) on orthodontic tooth movement during maxillary molar distalization over 12-week observation period.
- Trial name
- NCT05550168
- Testing
- Low Level Laser therapy
- Where
- Cyprus
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Near East University, Turkey
COVID-19, Respiratory Failure
Photobiomodulation Therapy Combined With Static Magnetic Field in Patients With COVID-19
Coronavirus disease 2019 (COVID-19) is a disease caused by a novel coronavirus called SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2).
- Trial name
- NCT04386694
- Testing
- Active PBMT/sMF
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- University of Nove de Julho
Cicatrix, Hypertrophic, Burns
Laser Therapy for Pediatric Burn Scars
A new era of outcomes for pediatric burn patients has begun as burn care continues to improve. Unfortunately, complete restoration of burn-injured skin may be limited by the development of hypertrophic scarring.
- Trial name
- NCT02707627
- Testing
- Laser Therapy
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- The Hospital for Sick Children
Juvenile Idiopathic Arthritis
Effect of Pulsed Magnetic Field Versus Low Level Laser Therapy on Functional Performance in Children With Juvenile Idiopathic Arthritis
the purpose of this study is to compare between the effect of pulsed magnetic field versus low level laser therapy on functional performance in children with juvenile idiopathic arthritis
- Trial name
- NCT06226012
- Testing
- pulsed magnetic field, Low level laser
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Shrouk Abd Elmohsen Taha Basiony Elnhrawy
Class II Division 1 Malocclusion
Effect of Low-level Laser Therapy During Maxillary Molar Distalization Using a Skeletally Anchored Appliance
study will be directed to evaluate the effect of low-level laser therapy during maxillary molar distalization using a skeletally anchored appliance
- Trial name
- NCT05465473
- Testing
- Distalization
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Autism
Photobiomodulation on Core Symptoms of Autism
This study aims to evaluate the effectiveness of photobiomodulation therapy on core symptoms in children with autism spectrum disorder.
- Trial name
- NCT07542899
- Testing
- Photobiomodulation
- Volunteers
- 30 people
- Sponsor
- Suez University
Impacted Third Molar Tooth
Comperasion the Postoperative Effect of Low Laser Therapy and Platelet Rich Fibrin on Mandibular Third Molar Surgery.
The aim of this study was investigate the comparison of postoperative effects of low laser treatment and platelet-rich fibrin application on mandibular impacted third molar tooth extraction.
- Trial name
- NCT06262945
- Testing
- Diagnoses, traditional osteotomies, platelet rich fibrin
- Where
- Cyprus
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Beste Erismen
Primary Dysmenorrhea, Traditional Chinese Medicine
Traditional Chinese Medicine, Western Medicine and Low-level Light Therapy（LLLT） for Primary Dysmenorrhea（PD）
To observe the clinical efficacy and safety of three methods for the treatment of primary dysmenorrhea. Establish an integrated biomarker index system for the evaluation of the efficacy of traditional Chinese medicine, western…
- Conditions
- Primary Dysmenorrhea, Traditional Chinese Medicine, Light
- Trial name
- NCT03953716
- Testing
- low level light therapy, DING KUN DAN, Simulated drug of DING KUN DAN
- Where
- China
- Volunteers
- 480 people
- Sponsor
- Peking Union Medical College Hospital
Arthroplasty, Replacement, Hip
Effects of Photobiomodulation Therapy (PBMT) in Total Hip Arthroplasty
Osteoarthritis (OA), a chronic degenerative muscle disease characterized by cartilage wear, causes progressive joint deformity and loss of function leading to the indication of total hip arthroplasty (THA), when conservative…
- Trial name
- NCT02970890
- Testing
- Portable Pain Away™
- Where
- Brazil
- Volunteers
- 18 people
- Sponsor
- Adriane Aver Vanin
Retinopathy of Prematurity (ROP)
Aflibercept for Retinopathy of Prematurity - Intravitreal Injection Versus Laser Therapy
The purpose of this study is to demonstrate how well aflibercept works in babies with ROP, comparing it with laser therapy. The study also has the objective to demonstrate how safe aflibercept is when used in babies, and describe…
- Trial name
- FIREFLEYE (NCT04004208)
- Testing
- Eylea (Aflibercept, BAY86-5321), Laser photocoagulation
- Where
- 90 sites in Argentina, Austria and 25 more
- Volunteers
- 113 people
- Sponsor
- Bayer
Photodynamic Therapy& Low Level Laser in Management of COVID 19
Photodynamic Therapy for the Treatment of COVID-19
Until now there is no vaccine or reliable treatment for the COVID-19 pandemic. The fundamental mechanisms of non-invasive low-level laser in photobiomodulation (PBM) and photodynamic therapy is to stimulate the mitochondrial…
- Trial name
- NCT04416113
- Testing
- photobiomodulation and photodynamic therapy
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Dental Caries, Irreversible Pulpitis
Clinical and Radiographic Assessment of Photobiomodulated MTA Pulpotomy in Immature First Permanent Molars with Irreversible Pulpitis
This study evaluates the effectiveness of photobiomodulation (PBM) in conjunction with mineral trioxide aggregate (MTA) pulpotomy for treating irreversible pulpitis in immature first permanent molars.
- Trial name
- NCT06730360
- Testing
- MTA Pulpotomy without photobiomodulation, MTA Pulpotomy with Photobiomodulation (LLLT)
- Where
- Egypt
- Volunteers
- 72 people
- Sponsor
- Mansoura University
Malocclusion
OrthoPulse 2.0 and 2.1 Feasibility Evaluation
OrthoPulse is a device that uses near-infrared light therapy in order to decrease orthodontic treatment time. The aim of this study is to evaluate OrthoPulse products modified with extended arrays, OrthoPulse 2.0 and OrthoPulse…
- Trial name
- BX13 (NCT03683017)
- Testing
- OrthoPulse 2.0, OrthoPulse 2.1, Invisalign 3.5 Day Wear
- Where
- 7 sites in United States, Canada
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Biolux Research Holdings, Inc.
Malocclusion, Angle Class I, Crowding
The Role of Low Level Laser Therapy in Acceleration of Teeth Alignment in Lingual Orthodontic Patients
We will treat patients with class I malocclusion who have moderate crowding (4-6 mm) according to Little's irregularity index and asses the efficacy of low level laser therapy in accelerating orthodontic tooth movement .
- Trial name
- NCT03646942
- Testing
- low level laser therapy, Lingual Orthodontics
- Where
- Syria
- Volunteers
- 36 people
- Sponsor
- Damascus University
Mucositis Oral
Evaluation of Prophylactic Photobiomodulation Therapy in Patients With Osteosarcoma
This study aims to evaluate the photobiomodulation therapy (PBMT) for the prevention of oral mucositis in osteosarcoma patients submitted to high doses of methotrexate, through two different protocols.
- Trial name
- PBMT/MTX (NCT06217224)
- Testing
- Preventive photobiomodulation Therapy (PBMT)
- Where
- Brazil
- Volunteers
- 53 people
- Sponsor
- Instituto Nacional de Cancer, Brazil
Low Level Laser Therapy, Canine Retraction
Three-dimensional Assessment of the Bone Changes Accompanying Laser-assisted Orthodontic Tooth Movement
Aim of the present study is to evaluate the effect of low-level laser therapy on bone quality and quantity with orthodontic tooth movement.
- Conditions
- Low Level Laser Therapy, Canine Retraction, Orthodontic Tooth Movement
- Trial name
- NCT05811728
- Testing
- Low level laser therapy, without beam emission
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Nourhan M.Aly
Periodontitis, Kidney Transplant Recipients
Diode Laser-Assisted Periodontal Therapy in Kidney Transplant Recipients
This randomized controlled trial evaluates the efficacy of diode laser-assisted non-surgical periodontal therapy in kidney transplant recipients with periodontitis.
- Trial name
- KTRs (NCT07532694)
- Testing
- Scaling and Root Planing, Diode Laser
- Where
- 2 sites in Vietnam
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Military Hospital 103
Low-grade Glioma, Recurrent Low Grade Glioma
Efficacy of Laser Interstitial Thermal Therapy in Young Persons With Low-grade Glioma
This study aims to evaluate the efficacy of Laser Interstitial Thermal Therapy (LITT) in treating recurrent or progressive, low-grade gliomas (LGG) in pediatric, adolescent and young adult patients.
- Conditions
- Low-grade Glioma, Recurrent Low Grade Glioma, Low Grade Glioma of Brain, Pediatric Cancer
- Trial name
- NCT07506239
- Testing
- Laser Interstitial Thermal Therapy (LITT), Magnetic resonance imaging (MRI), Questionnaires
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of California, San Francisco