Clinical trials: Pediatric Cataract
Capsular Contracture, Implant, Pediatric Cataract
Capsular Outcomes of Pediatric Cataract Surgery With Primary Intraocular Lens Implantation
Lens capsular often changes after pediatric cataract surgery，causing complications such as anterior capsulerhexis shrinkage, visual axis opacification (VAO), zonular dehiscence and so on.
- Trial name
- capsular (NCT04803097)
- Where
- China
- Volunteers
- 62 people
- Sponsor
- Yune Zhao
Pediatric Glaucoma
Combined Phacoaspiration and Angle Surgery Versus Phacoaspiration in Pediatric Cataract
The aim of this study is to report the effectiveness of phacoaspiration when combined with angle surgery in preventing postoperative glaucoma following pediatric cataract surgery
- Trial name
- NCT05401760
- Testing
- Group A :combined phacoaspiration and angle surgery, Group B : phacoaspiration only
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Mansoura University
Peripheral Vascular Access in Pediatric Patients, Peptic Ulcer
The Effect of Vascular Imaging Devices on Success Rates of Peripheral Vascular Access in Pediatric Patients
The study was designed as a prospective, observational study. Pediatric patients under 18 years of age scheduled for peripheral vascular access placement during day-case surgery or non-operating room anesthesia (NORA) will be…
- Conditions
- Peripheral Vascular Access in Pediatric Patients, Peptic Ulcer, Cataract, Crohn's Disease
- Trial name
- NCT07315711
- Where
- 6 sites in Turkey (Türkiye)
- Volunteers
- 500 people
- Sponsor
- Sibel Seçkin Pehlivan
Cataract
An Interocular Comparative Study of Unilateral Cataract
The purpose of this cross-sectional study is to compare bilateral anterior segment parameters, macular thickness, and BCVA at 3 months after uncomplicated unilateral pediatric cataract extraction with primary IOL implantation to…
- Trial name
- NCT02765230
- Where
- China
- Volunteers
- 53 people
- Sponsor
- Sun Yat-sen University
Inflammation
Clinical Trial on Anti-inflammatory Effect of Low-Molecular Weight Heparin in Pediatric Cataract Surgery
The purpose of this study is to determine if intraocular infusion of low-molecular weight heparin (enoxaparin) influences postoperative inflammation following pediatric cataract surgery with intraocular lens (IOL) implantation.
- Trial name
- NCT00986076
- Testing
- Enoxaparin, Balanced Salt Solution
- Where
- India
- Volunteers
- 23 people
- Sponsor
- Iladevi Cataract and IOL Research Center
Congenital Cataract
Iridocorneal Angle and Anterior Segment Structure in Eyes of Children With Cataract
The aim of this study is to evaluate the morphology of iridocorneal angle and anterior segment structure in children with cataract, and to explore potential preoperative structural clues for postoperative glaucoma.
- Trial name
- ACA (NCT03778086)
- Testing
- gonioscopy
- Volunteers
- 100 people
- Sponsor
- Wenzhou Medical University
Congenital Cataract, Pediatric Cataract
Five-Year Visual Function and Refractive Outcomes After Congenital Cataract Surgery
This prospective multicenter observational study aims to evaluate the 5-year visual function and refractive outcomes in children undergoing surgery for congenital cataract.
- Trial name
- NCT07070037
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Jin Yang
Pediatric Cataract
Outcome of Capsular After Pediatric Cataract Surgery With Primary Intraocular Lens Implantation
The aim of this study is to evaluate the outcome of capsular in children with cataract, and to explore potential preoperative structural clues for postoperative glaucoma.
- Trial name
- Capsular (NCT04357249)
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Wenzhou Medical University
Congenital Cataract
Capsulorhexis Size and Capsular Outcome
Different capsulorhexis size results in different capsular outcome when treating pediatric cataract, and there should be an appropriate capsulorhexis size for the best capsular outcome.
- Trial name
- NCT02158325
- Testing
- anterior capsulorhexis sizes
- Where
- China
- Volunteers
- 38 people
- Sponsor
- Sun Yat-sen University
Pediatric Cataract, Congenital Cataract
Toric Intraocular Lens Implantation for Pediatric Aphakia
Here, we conducted a nonrandomized clinical trial aims to evaluate and compare the prognosis of visual function in children of these two types of IOL implantation over a three-year postoperative period.
- Trial name
- NCT07088796
- Testing
- Toric IOL implantation, Non-toric IOL implantation
- Where
- China
- Volunteers
- 236 people
- Sponsor
- Eye & ENT Hospital of Fudan University
Congenital Cataract, Aphakic or Pseudophakic Glaucoma
Mechanism of Aphakic and Pseudophakic Glaucoma in Pediatric Patients
In cell cultures, lens epithelial cells and trabecular meshwork cells will be exposed to aqueous humor from pediatric eyes undergoing cataract removal surgery.
- Trial name
- NCT01136473
- Where
- Israel
- Volunteers
- 40 people
- Sponsor
- Carmel Medical Center
Cataract in Child
FLACS in Pediatric Patients Using FEMTO LDV-Z8
This study is a single center prospective observational case series. The framework of this clinical investigation is post market clinical follow up of pediatric FLACS using the Femto LDV Z8.
- Trial name
- NCT05241756
- Testing
- FLACS using FEMTO LDV-Z8
- Where
- Belgium
- Volunteers
- 12 people
- Sponsor
- Ziemer Ophthalmic Systems AG
Cataract
Evaluation of Therapeutic Strategies in Pediatric Cataract Surgery
The purpose of this observational study is to assess the therapeutic strategies in the treatment of pediatric cataracts.
- Trial name
- EP3C (NCT02253017)
- Testing
- Children operated on for cataract
- Where
- France
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Lowe Syndrome
Genetic Analysis of Oculocerebrorenal Syndrome of Lowe
This study will investigate the genetic basis of oculocerebrorenal syndrome of Lowe (OCRL)-a rare X-linked disorder (carried by females and passed to males).
- Trial name
- NCT00359515
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- National Human Genome Research Institute (NHGRI)
Endophthalmitis, Cataracts Infantile
Nylon Verus Polyglactin Corneal Suture in Pediatric Cataract Surgery
Pediatric cataract surgery requires the suturing of the corneal incision in order to maintain the integrity of the eyeball and to help avoid the trauma often caused by scratching in the postoperative period of pediatric…
- Conditions
- Endophthalmitis, Cataracts Infantile, Suture, Complication
- Trial name
- NCT03812640
- Testing
- Vicryl suture, Nylon suture
- Where
- Brazil
- Volunteers
- 80 people
- Sponsor
- University of Campinas, Brazil
Contrast Sensitivity
Contrast Sensitivity Assessment in Pediatric Cataract Surgery With IOL Implantation
The study evaluates contrast sensitivity in older children following surgery for lamellar and posterior subcapsular cataracts. Often, pediatric surgeons tend to delay surgery in these children who present beyond the amblyogenic…
- Trial name
- NCT01901744
- Testing
- Cataract Surgery
- Where
- India
- Volunteers
- 25 people
- Sponsor
- Iladevi Cataract and IOL Research Center
Traumatic Cataract
Long-term Visual and Refractive Outcomes After Traumatic Cataract Surgery in Children
This prospective multicenter observational study aims to evaluate long-term visual and ocular biometric outcomes in pediatric patients aged 0-16 years who were diagnosed with traumatic cataract and underwent cataract extraction…
- Trial name
- NCT07087275
- Where
- China
- Volunteers
- 600 people
- Sponsor
- Jin Yang
Posterior Capsule Opacification, Postoperative Complications
Clinical Trial : Complications of in the Bag IOL Versus Optic Capture of IOL in Pediatric Cataract Surgery
This prospective, randomized, clinical trial looks to compare children undergoing congenital cataract surgery with intraocular lens (IOL) implantation in terms of visual axis obscuration as well as postoperative complications…
- Trial name
- NCT02491918
- Testing
- cataract surgery, Intraocular lens implantation
- Volunteers
- 61 people
- Sponsor
- Iladevi Cataract and IOL Research Center
Ventilation, Laryngeal Mask Airway
Impact of Different Modes of Ventilation With Laryngeal Mask Airway on Pediatric Cataract Surgery
This study will be conducted to evaluate effects of different modes of ventilation on pediatric cataract surgery aiming to a peri-operative stable anesthesia, better surgical satisfaction and post operative recovery.
- Conditions
- Ventilation, Laryngeal Mask Airway, Cataract Surgery
- Trial name
- NCT04241653
- Testing
- Pressure Support Ventilation, Unparalyzed Pressure Control Ventilation, Paralyzed Pressure Control Ventilation
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Sameh Fathy
Cataract
Evaluate the Safety of DEXYCU for the Treatment of Inflammation Following Ocular Surgery for Childhood Cataract
A Phase 3/4, Prospective, Randomized, Active Treatment-Controlled, Parallel-Design, Multicenter Study to Evaluate the Safety of DEXYCUfor the Treatment of Inflammation Following Ocular Surgery for Childhood Cataract
- Trial name
- NCT05191706
- Testing
- Dexamethasone, Prednisolone Acetate Ophthalmic
- Where
- 9 sites in United States
- Volunteers
- 17 people
- Sponsor
- EyePoint Pharmaceuticals, Inc.