Clinical trials: Patient-Controlled Analgesia
Brachial Plexus Injury
Incidence of Brachial Plexus Injury After Rotator Cuff Repair With Continuous Interscalene Block
Brachial plexus injury after shoulder surgery with continuous interscalene block is 2.4% at 1 month and 0% at 6 months, but may be higher with a systematic postoperative neurological examination.
- Trial name
- NCT01334632
- Testing
- Continuous interscalene block, PCA morphine
- Where
- Switzerland
- Volunteers
- healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Regional Anesthesia
Comparison of Caudal Block and Retrolaminar Block for Circumcision
Primary Outcome: Analgesic Efficiency: The primary outcome is the comparison of the analgesic efficacy of the retrolaminar block (RL) versus caudal block (CB) based on postoperative pain scores measured by the FLACC score.
- Trial name
- NCT06584292
- Testing
- caudal block, Retrolaminar block
- Where
- Turkey (Türkiye)
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Critical Limb Ischemia, Arterial Occlusive Disease
Randomized Study of Pregabalin for Pain Reduction in Patients With Rest Pain and Lower Limb Ischemia
The hypothesis behind the trial is the concept that Pregabalin is effective in reducing pain at rest in lower limb ischemia, and the study evaluates active treatment or placebo added to the regular pain regimens for these…
- Conditions
- Critical Limb Ischemia, Arterial Occlusive Disease, Pain, Ischemia
- Trial name
- NCT00403780
- Testing
- pregabalin
- Where
- 3 sites in Sweden
- Volunteers
- 18 people
- Sponsor
- Karolinska Institutet
Postoperative Nausea and Vomiting
Antiemetic Effect of the Addition of Ondansetron to the Morphine Solution in Patient-Controlled Analgesia (PCA)
PCA morphine always introduces nausea and vomiting during the postoperative period. Ondansetron can reduce PONV (postoperative nausea vomiting).
- Trial name
- NCT00199329
- Testing
- ondansetron adding in PCA
- Where
- Thailand
- Volunteers
- 160 people
- Sponsor
- Khon Kaen University
Prostate Cancer
Postoperative Pain Control for Prostatectomy
The researchers propose to investigate a relatively new anesthetic procedure, in order to maximize patient comfort and minimize the use of narcotics after a radical prostatectomy.
- Trial name
- TAP (NCT00913068)
- Testing
- Transverse Abdominal Plan (TAP), standard post op pain control
- Where
- Canada
- Volunteers
- 110 people
- Sponsor
- Nova Scotia Health Authority
Neuromuscular Block, Residual, Pain Management
Methylprednisolone vs Dexamethasone Interaction With Sugammadex in Pediatric Patients
This randomized controlled trial aims to compare the interaction of methylprednisolone and dexamethasone with sugammadex in pediatric patients undergoing adenoidectomy and/or tonsillectomy.
- Conditions
- Neuromuscular Block, Residual, Pain Management, Postoperative Nausea
- Trial name
- NCT07175623
- Testing
- Methyl Prednisolone (MP), Dexamethasone (0.2 mg/kg), Saline (0.9% NaCl)
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Konya City Hospital
Postoperative Analgesia
Intravenous Paracetamol in Combination With Caudal Ropivacaine
To investigate whether the addition of intravenous paracetamol with caudal ropivacaine leads to better quality of postoperative recovery in patients undergoing hypospadius repair than caudal ropivacaine alone.
- Trial name
- NCT03781505
- Testing
- Paracetamol +caudal ropivacaine
- Where
- Pakistan
- Volunteers
- 64 people
- Sponsor
- Aga Khan University
Pain, Acute
Bilateral Ultrasound-Guided Intra Muscular Quadratus Lumborum Block Versus Trans Muscular Quadratus Lumborum Block for Peri-Operative Analgesia in Abdominal Surgeries in Pediatric Patients. A Comparative Controlled Randomized Study.
To compare between the intra muscular quadratous lamborum and the Trans muscular quadratous lamborum in pediatric population under going abdominal surgeries regards to first request of rescue analgesia, degree of pain relief…
- Trial name
- NCT04029987
- Testing
- Bilateral Ultrasound-Guided Transmuscular Quadratus Lumborum Block., Bilateral Ultrasound-Guided intra smuscular Quadratus Lumborum Block., Control
- Where
- Egypt
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Kasr El Aini Hospital
Pain, Fear
Intramuscular Injection-Related Pain and Fear
The study is an experimental randomized controlled study conducted to compare the effect of buzzy and shotblocker methods applied during intramuscular injection from on pain and fear level in 6-12 year-old children.
- Trial name
- NCT03915704
- Testing
- Shotblocker, Control, Buzzy
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Istanbul Saglik Bilimleri University
Anesthesia, Local
Pain Control of Needle-free Versus Needle Injected Local Anesthesia for Pulpotomy of Upper Primary Molars in Children
This is a study that will be conducted on 6 to 8 years old children to compare the needle-less jet injector with the conventional needle attached syringe in terms of efficiency in controlling pain of local anesthetic infiltration…
- Trial name
- NCT03917121
- Testing
- Jet injector, Needle attached dental syringe
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Cairo University
Irreversible Pulpitis, Tooth Extraction
Efficacy of Computer Controlled Intraosseous Anesthesia in Pediatric Dental Patients
To evaluate the effectiveness of intra-osseous anesthesia using Quicksleepr5 in pain elimination during dental treatment in maxillary and mandibular primary molars, compared to conventional anesthesia.
- Trial name
- NCT06245161
- Testing
- Quicksleeper5, conventional anesthesia
- Where
- Egypt
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Dexmedetomidine
Dexmedetomidine and Sufentanil Effect in PCA on Pediatric Patients Undergoing Scoliosis Surgery
The primary purpose of this three-arm single center, randomized, subject and assessor blind, controlled clinical study is to evaluate the effect of dexmedetomidine on patient-controlled intravenous analgesia after pediatric…
- Trial name
- DEX (NCT05249153)
- Testing
- low dose of dexmedetomidine with sufentanil, high dose of dexmedetomidine with sufentanil
- Where
- China
- Volunteers
- 84 people
- Sponsor
- Peking Union Medical College Hospital
Postoperative Pain
Peripheral Nerve Block Techniques During Cleft Palate
Regional blocks are commonly used in pediatric anesthesia to achieve adequate postoperative analgesia. Suprazygomatic Maxillary nerve block (SMN) and Greater Palatine nerve block (GPN) are regional blocks described for use during…
- Trial name
- NCT04467463
- Testing
- peripheral nerve block by 0.25% levobupivacaine
- Where
- 2 sites in Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Postoperative Pain
Intraoperative Local Anaesthetic and Postoperative Pain
Background: Intraoperative wound infiltration with local anaesthetic is commonly used. Apart from the obvious immediate action it has been supported that a possible down regulation of pain receptors may lead to longer effects.
- Trial name
- Pain-1 (NCT02171299)
- Testing
- Wound infiltration with local anaesthetic, Ropivacaine
- Where
- Greece
- Volunteers
- 400 people
- Sponsor
- Hellenic Red Cross Hospital
Pain Management, Orthopedic Procedure Pain
The Analgesic Efficacy of Nefopam in Orthopedics Surgery
Pain-free and relief are one of the anesthesiologist's most important concerns during the operation. General aim is always to effectively control pain but while simultaneously reducing opioid requirements to reduce opioid related…
- Trial name
- NCT06680609
- Testing
- Nefopam 20 MG/ML
- Where
- Jordan
- Volunteers
- 49 people
- Sponsor
- King Abdullah University Hospital
Recurrent Tonsillitis, Obstructive Sleep Apnea
Post-operative Pain Control After Pediatric Adenotonsillectomy
Adenotonsillectomy is one of the most common surgical procedures performed in the pediatric population in the United States. It is generally a well-tolerated procedure with post-operative bleeding risk ranging from 3-5% in…
- Conditions
- Recurrent Tonsillitis, Obstructive Sleep Apnea, Sleep Disordered Breathing, Adverse Reaction to Drug
- Trial name
- NCT02296840
- Testing
- Ibuprofen, Hydrocodone-Acetaminophen
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Emory University
Analgesia
Erector Spinae Block Versus Caudal Block for Perioperative Analgesia in Pediatric Cancer Patients
The study aim to compare ultrasound guided erector spinae plane block versus ultrasound guided caudal block in perioperative analgesia for pediatric cancer patients
- Trial name
- NCT05153720
- Testing
- Erector spinae plane block, Caudal block
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- National Cancer Institute, Egypt
Pectus Excavatum, Pain, Postoperative
Sub-Paraspinal Block in Nuss Patients. A Pilot Project
The purpose of this pilot study was to evaluate effectiveness of a novel regional anesthesia technique developed at the investigators institution, as part of a quality improvement initiative, to assist with multilevel thoracic…
- Trial name
- NCT02169297
- Testing
- Ultrasound-guided Sub-Paraspinal Block, PCA only
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Nemours Children's Clinic
Pain, Nausea
Optimal Dose of Prophylactic Naloxone in Reducing Opioid-Induced Side Effects in Children/Adolescents
This is an investigator initiated dose finding study designed to determine the optimal dose of naloxone to prevent or minimize the most common side effects induced by opioids, namely itching, nausea, and vomiting.
- Conditions
- Pain, Nausea, Pruritus
- Trial name
- NCT00330343
- Testing
- naloxone
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Johns Hopkins University
Non-Pharmacological Interventions, Breathing Exercise
Effect Of Game-Based Breathing Exercise On Pain, Fear, And Anxiety In Children During Venipuncture
Venipuncture is one of the most common invasive procedures in children and is often associated with significant pain, fear, and anxiety.This randomized controlled study will aim to evaluate the effects of a video game-based…
- Conditions
- Non-Pharmacological Interventions, Breathing Exercise, Venipuncture Pain, Pain Management
- Trial name
- NCT07550062
- Testing
- Intervention Group (Video Game-Based Breathing Exercise During Venipuncture), Video Game-Based Breathing Exercise Device
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Uludag University