Clinical trials: Occlusal Changes
Full Mouth Rehabilitation, Canine Overlap Relation
Canine Occlusal Relationship Changes After Stainless-Steel Crown Placement Under General Anesthesia
The aim of the study is to Assess and compare canine occlusal relation in children with carious primary molars before they are treated by stainless steel crowns under general anaesthesia and after their placement, evaluate the…
- Conditions
- Full Mouth Rehabilitation, Canine Overlap Relation, General Anesthesia
- Trial name
- NCT04731337
- Testing
- Digital Caliper (Shenzhen Jiabaili Electronic Commerce Co., Ltd)
- Where
- Egypt
- Volunteers
- 178 people
- Sponsor
- Cairo University
Sickle Cell Disease, Vaso-occlusive Pain Episodes
Virtual Reality As Adjunct Therapy for Vaso-Occlusive Pain
The goal of this randomized control clinical trial is to learn if virtual reality can be used to treat sickle cell pain in children.
- Trial name
- NCT06773715
- Testing
- KindVR Aqua Program
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Louisiana State University Health Sciences Center in New Orleans
Mouthguard Use Orofacial Injuries Prevention 3D Printed Mouthguard Traditional Custom-made Mouthguard Occlusal Thickness Changes
Comparative Assessment of Thickness Changes in 3D-Printed vs. Custom-Made Mouth Guards for Children in Contact Sports
This study aims to compare changes in the thickness of traditional and 3D-printed custom mouth guards in pediatric athletes who participate in contact sports.
- Trial name
- NCT07000435
- Testing
- 3D printed custom-made mouth guards, Traditional custom-made mouth guards
- Where
- Egypt
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Cairo University
Caries Prevention
Effectiveness of Using (Vanish XT) in Prevention of Occlusal Caries: a RCT
Despite the continuous effort to prevent and treat dental caries, it continues to be one of the most common chronic diseases in both children and adults.
- Trial name
- NCT04579536
- Testing
- Light curable resin modified glass ionomer varnish, Vanish White Varnish
- Where
- Saudi Arabia
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- King Abdulaziz University
Dental Caries, Dental Occlusion
Occlusal Impact of Hall Crowns in Primary Molars
Hall Technique is a non-invasive restorative approach for managing carious primary molars, increasingly used in pediatric dentistry due to its simplicity and patient tolerance.
- Conditions
- Dental Caries, Dental Occlusion, Pediatric Dentistry
- Trial name
- NCT07134114
- Testing
- Hall Technique
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ankara Yildirim Beyazıt University
General Anesthesia
Canine Occlusal Relationship Changes After Full Mouth Rehabilitation Under General Anesthesia
The aim of the study is to assess and compare canine occlusal relation in children with carious primary molars before they are treated by stainless steel crowns under general anesthesia and after their placement ,to evaluate the…
- Trial name
- NCT04729673
- Testing
- Digital caliper (Shenzhen Jiabaili Electronic Commerce Co., Ltd)
- Where
- Egypt
- Volunteers
- 73 people
- Sponsor
- Cairo University
Caries; Dentin, Fissure, Dental
Sealing of Occlusal Dentin Caries in Primary Molars.
BACKGROUND A simple method for arresting dentin caries with a tight seal of the cavity would exclude the need for injection and excavation, reduce the risk for dental fear and possibly postpone or eliminate the need for further…
- Conditions
- Caries; Dentin, Fissure, Dental, Dental Caries in Children, Glass Ionomer Cement
- Trial name
- SealCar (NCT05475145)
- Testing
- Resin based sealing [RBS]
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Mats Bågesund
Moyamoya Disease
The Role of m6A RNA Modification in Moyamoya Disease
The purpose of this study is to detect the change of m6A RNA modification from peripheral blood of patients with moyamoya disease, and to assess the relationship between clinical characteristics.
- Trial name
- NCT04696094
- Where
- China
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Beijing Tiantan Hospital
Hypothermia, Preterm Infant
Heat Loss Prevention in Very Preterm Infants in Delivery Rooms: A Multicenter, Randomized, Controlled Trial of Polyethylene Occlusive Total Body Skin Wrapping
Hypothermia after delivery is a world-wide problem associated with morbidity and mortality. The conventional approach of drying the baby with a pre-warmed towel and radiant warmers is unsuccessful in a large proportion of very…
- Trial name
- NCT01671241
- Testing
- Polyethylene wrap
- Where
- Italy
- Volunteers
- 80 people
- Sponsor
- University of Padova
Coronary Artery Disease
Hemodynamic Changes in Off-pump Coronary Artery Bypass Grafting
The purpose of this study is to study the positioning and stabilization of different cardiac walls performed during off-pump coronary artery bypass grafting (CABG) may have dissimilar impact on hemodynamics.
- Trial name
- NCT00967278
- Where
- Brazil
- Sponsor
- University of Sao Paulo
Atherosclerosis, Cardiovascular Risk Factor
Early Vascular Ageing in the YOUth
This is a single-center observational study on adolescents to determine predictors of the early steps of the formation of atherosclerosis and to quantify their influence on Intima-Media-Thickness of the carotid artery and the…
- Conditions
- Atherosclerosis, Cardiovascular Risk Factor, Cardiovascular Diseases, Cardiovascular Pathology
- Trial name
- EVA4YOU (NCT04598685)
- Where
- Austria
- Volunteers
- 1,517 people, healthy volunteers welcome
- Sponsor
- VASCage GmbH
Adenine Phosphoribosyltransferase Deficiency, AH Amyloidosis
National Registry of Rare Kidney Diseases
The goal of this National Registry is to is to collect information from patients with rare kidney diseases, so that it that can be used for research.
- Conditions
- Adenine Phosphoribosyltransferase Deficiency, AH Amyloidosis, AHL Amyloidosis, AL Amyloidosis
- Trial name
- RaDaR (NCT06065852)
- Where
- United Kingdom
- Volunteers
- 35,000 people
- Sponsor
- UK Kidney Association
Coronary Artery Disease
Evaluation Rehabilitation on Glycometabolic State in Non-Diabetic Coronary Artery Disease (CAD) Patients
The purpose of this study is to evaluate the effects of an intensive Cardiac rehabilitation program on glucose metabolism of non-diabetic coronary artery disease patients.
- Trial name
- NCT00917930
- Testing
- physical training
- Sponsor
- IRCCS San Raffaele
Cardiovascular Diseases, Heart Diseases
Early Atherosclerosis Change in Two Clinical Trials
To complete end point analysis for the Monitored Atherosclerosis Regression Study (MARS) and to compare coronary versus carotid treatment effect relationships in MARS to coronary versus carotid treatment effect relationships in…
- Conditions
- Cardiovascular Diseases, Heart Diseases, Carotid Artery Diseases, Coronary Disease
- Trial name
- NCT00005696
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Sickle Cell Disease, Sickle-Cell Disease With Crisis
Investigation Into the Use of BAH243 Lentiviral Vector for Gene Therapy in Treating Sickle Cell Disease
This study is an open-label, non-randomized, single-dose Phase 1/2 trial involving around 85 adult and pediatric participants aged between 2 and 50 years with sickle cell disease (SCD).
- Trial name
- BAH243 (NCT06399107)
- Testing
- Drug Product is administered by IV infusion following myeloablative conditioning with busulfan
- Where
- China
- Volunteers
- 85 people
- Sponsor
- Essen Biotech
Acne, Peeling
Efficacy of Different Types of Chemical Peels in the Treatment of Acne Vulgaris
Assessment of the Efficacy and Safety of 50% Glycolic Acid, 30% Salicylic Acid, and Modified Jessner's Chemical Peels in the Treatment of Active Acne and Post-acne Hyperpigmentation: Randomized Controlled Trial.
- Trial name
- AV (NCT07240051)
- Testing
- Glycolic acid peel alone, salicylic acid, modified jessener
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Nahla Maher Mahmoud Mahran
Occlusal Caries
Management of Occlusal Caries Using Silver Modified Atraumatic Restorative Treatment Versus Atraumatic Restorative Treatment
Silver modified atraumatic restorative treatment (intervention) or atraumatic restorative treatment (Control) will be used to manage occlusal caries in preschool children then the molars will be evaluated at the interval of 3,6…
- Trial name
- NCT04354636
- Testing
- Silver modified atraumatic restorative treatment, Atraumatic restorative treatment
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cairo University
Hypothermia in Premature Infants
Multicentre Randomised Controlled Trial of HELP (Heat Loss Prevention) in the Delivery Room
Does polyethylene occlusive wrap applied immediately after delivery to infants born at less than 28 weeks gestation decrease all-cause mortality measured at discharge compared with the standard of care as determined by the…
- Trial name
- HeLP (NCT00607464)
- Testing
- Polyethylene occlusive skin wrap
- Where
- Canada
- Volunteers
- 804 people
- Sponsor
- Sunnybrook Health Sciences Centre
Dental Caries, Dental Occlusion
Occlusal Changes After Modified Hall Technique in Molars Affected by Molar-Incisor Hypomineralization
Molar-incisor hypomineralization (MIH) frequently affects permanent first molars and increases the risk of rapid post-eruptive breakdown and restorative failure.
- Conditions
- Dental Caries, Dental Occlusion, Pediatric Dentistry
- Trial name
- NCT07530835
- Testing
- Modified Hall Technique
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Ankara Yildirim Beyazıt University
Dental Caries
Occlusal Bite Force Changes After Placement of Stainless Steel Crowns in Children
The aim of this study was to determine if restoring primary molars with SSCs would improve children's OBF.
- Trial name
- OBF (NCT03254069)
- Testing
- Stainless Steel Crowns
- Where
- Jordan
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Jordan University of Science and Technology