Clinical trials: Neurological Development
Development
Neurodevelopmental Outcomes of Preterm Infants Treated for Pain Management With Repeated Doses of Sucrose 24%
The purpose of this study is to determine the effect of sucrose 24% for pain prevention on preterm infants. Our hypothesis is that repeated doses of sucrose 24%, given prior to painful procedure,do not impair neurodevelopmental…
- Trial name
- NCT01742520
- Testing
- multiple doses of sucrose, Formula or breast milk
- Where
- Israel
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Autism Spectrum Disorder, Autism
Dynamic Quantification of Social-Visual Engagement in Autism Spectrum Disorder (ASD)
The goal of this clinical study is to learn about the utility and performance of the EarliPoint System (™): Evaluation for Autism Spectrum Disorder to diagnose and assess autism spectrum disorder (ASD) in children ages 31-96…
- Trial name
- MEASURE-ASD2 (NCT05806216)
- Testing
- EarliPoint Diagnosis, Clinically Certain Expert Clinician Diagnosis (CC-ECD)
- Where
- 9 sites in United States
- Volunteers
- 929 people, healthy volunteers welcome
- Sponsor
- EarliTec Diagnostics, Inc
Cerebral Palsy, Muscular Dystrophies
Turkish Version of The Measure of Processes of Care (MPOC)
Family-centred care (FCS) is considered the best practice in providing rehabilitation to children with disabilities and special needs.
- Conditions
- Cerebral Palsy, Muscular Dystrophies, Autism Spectrum Disorder, Traumatic Brain Injury
- Trial name
- NCT03508583
- Testing
- Participation
- Volunteers
- 300 people
- Sponsor
- Hacettepe University
Deafness, Hearing Loss
Outcomes In Children With Developmental Delay And Deafness
Children with special needs require complex, individualized therapy to maximize their long-term quality of life. One subset of children with special needs includes those with both developmental delays and deafness.
- Trial name
- NCT01256229
- Testing
- cochlear implantation, hearing aids
- Where
- 2 sites in United States
- Volunteers
- 303 people
- Sponsor
- Stanford University
Developmental Delay
Effects of Power Ball on Grip Strength in Children With Developmental Delay.
Developmental delay refers to the child who does not perform the normal milestones as other children accomplish in the same age within time or somehow late but can achieve them.
- Trial name
- NCT05392296
- Testing
- Power ball, isometric hand grip strengthening exercises
- Where
- Pakistan
- Volunteers
- 28 people
- Sponsor
- Riphah International University
Developmental Language Disorder
The Effect of Prior Learning on Treatment of Morpheme Errors
This is a small-scale treatment study designed to determine which teaching methods result in the best learning. Treatment focuses on helping children with a developmental language disorder learn parts of grammar.
- Trial name
- NCT05953077
- Testing
- Conversational recasting
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- University of Arizona
Autism Spectrum Disorder, Asperger Syndrome
Effects of a Multimodal Exercise Program for Children With ASD
Exploring the effects of an exercise program for children ages 6 -26 years old who have been diagnosed with autism spectrum disorder and neurotypical children respond to high-intensity whole body exercise interventions (Group 1)…
- Trial name
- NCT05509231
- Testing
- High-intensity exercise, Wearable glove and arm sleeve device to measure movement
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- New York Institute of Technology
Developmental Language Disorder
Sentence Prediction in Developmental Language Disorder
Millions of children - 7-12% of the school-age population - have developmental language disorder (DLD), a disorder that affects language learning, comprehension, and use.
- Trial name
- NCT07510854
- Testing
- Thematic role, Sentence complexity
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Father Flanagan's Boys' Home
Speech Articulation Disorder, Developmental Articulation Disorder
Randomized Clinical Trial of Phonological Interventions
Recent research reveals genetic and symptomatic overlap among children with speech sound disorders (i.e., those who (misarticulate more sounds than would be expected for their age) and children with dyslexia (i.e., those who…
- Conditions
- Speech Articulation Disorder, Developmental Articulation Disorder, Phonological Impairment, Dyslexia
- Trial name
- ECRIP (NCT00818428)
- Testing
- Speech Production Intervention, Speech Perception Intervention, Articulation Parent Group
- Where
- 2 sites in Canada
- Volunteers
- 96 people
- Sponsor
- McGill University
Development Delay, Motor Skills Disorders
Effect of a Telerehabilitation-Supported, Family-Centered Early Intervention Program on Neurodevelopmental and Parental Outcomes in Infants at Mild-to-Moderate Risk
The goal of this pilot randomized controlled trial is to learn whether a family-centered early intervention program, delivered remotely to parents and carried out at home, can support the development of infants who were treated…
- Conditions
- Development Delay, Motor Skills Disorders, Neurodevelomental Disorders, High Risk Infant
- Trial name
- NCT07878819
- Testing
- Remote Family-Centered Early Intervention Program, Standard Information and Routine Follow-up
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Bengisu Boz Gürboğa
Asperger's Disorder, Mental Retardation
Cognitive Neuroscience of Autism Spectrum Disorders
Background: Autism spectrum disorders (ASDs) are a group of developmental disorders that affect communication, social interaction, and behavior.
- Conditions
- Asperger's Disorder, Mental Retardation, Children, Adult
- Trial name
- NCT01031407
- Where
- United States
- Volunteers
- 678 people
- Sponsor
- National Institute of Mental Health (NIMH)
Hearing Impaired Children
Artificial Grammar Learning in Children Who Are Deaf or Hard-of-Hearing: Stimulus Length Effect
The goal of this basic experimental study involving humans (BESH) clinical trial is to examine how stimulus length affects grammar learning in children who are deaf or hard-of-hearing and who primarily use spoken language.
- Trial name
- NCT07782567
- Testing
- Short linguistic content, Long linguistic content
- Volunteers
- 30 people
- Sponsor
- University of Illinois Chicago
Autism Spectrum Disorder, Sleep Disorder
Evaluating the Effects of Tasimelteon in Individuals With Autism Spectrum Disorder (ASD) and Sleep Disturbances
This is a multicenter, open-label study to evaluate the efficacy and safety of a daily single oral dose of tasimelteon in treating sleep disturbances in pediatric and adult participants with ASD.
- Conditions
- Autism Spectrum Disorder, Sleep Disorder, Neurological Disorder, Sleep Disturbance
- Trial name
- NCT05361707
- Testing
- Tasimelteon Oral Capsule, Tasimelteon Liquid Suspension
- Where
- 5 sites in United States
- Volunteers
- 100 people
- Sponsor
- Vanda Pharmaceuticals
Craniosynostoses, Pain, Postoperative
Scalp Block Decreases Pain and Side Effects
Postoperative analgesia after corrective surgery of paediatric craniosynostosis is crucial in term of short and long-term outcomes.
- Trial name
- NCT04133467
- Testing
- scalp block
- Where
- Italy
- Volunteers
- 26 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Functional Neurological Disorder, Convulsion, Non-Epileptic
Establishment of an Interdisciplinary Functional Neurological Disorder (FND) Treatment Program and Development of a Clinical Care Pathway for FND
The purpose of this study is to help providers develop an interdisciplinary treatment pathway for functional neurological disorder (FND) at University of Alabama at Birmingham (UAB), and will involve psychiatry, speech therapy…
- Conditions
- Functional Neurological Disorder, Convulsion, Non-Epileptic, Functional Seizure
- Trial name
- NCT06362161
- Where
- United States
- Volunteers
- 1,100 people
- Sponsor
- University of Alabama at Birmingham
Typical Development, Risk of Dysgraphia
Graphomotor Intervention Program for Handwriting Difficulties Prevention in School-Age
12-30% of children present handwriting difficulties, which has negative repercussions on their school career. For this reason, it is fundamental to bet on their prevention.
- Conditions
- Typical Development, Risk of Dysgraphia, Dysgraphia
- Trial name
- NCT03699800
- Testing
- Graphomotor intervention program
- Where
- Portugal
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- University of Évora
Autism Spectrum Disorder, Developmental Delay
Pilot Study: A Telehealth Intervention for Caregivers of Infants With Early Signs of Autism Spectrum Disorder
Caregiver coaching will be provided using telehealth technology, in order to determine the efficacy and effectiveness of the telehealth medium of intervention delivery for caregivers of infants with concern for ASD.
- Trial name
- NCT03592654
- Testing
- infant telehelp
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Hypothyroidism, Global Developmental Delay
Register for Patients With Thyroid Hormone Resistance.
Thyroid hormones (TH) play a pivotal role in the development and function of the mammalian brain. Patients with impaired thyroid hormone transport into the brain tissue or in the case of defective local thyroid hormone receptor…
- Conditions
- Hypothyroidism, Global Developmental Delay, Intellectual Disability, Dystonia
- Trial name
- DEEPTYPE (NCT06566066)
- Testing
- no intervention
- Where
- Germany
- Volunteers
- 200 people
- Sponsor
- Charite University, Berlin, Germany
Hypotonia
Osteopathic Treatment on Motor Development of Hypotonic Infants.
Interventional study involving the human at risk and minimal constraint (RIPH2), randomized single-blind comparing the impact of osteopathic treatment on the axial tone of the hypotonic infant versus simulation
- Trial name
- HYPOSTEO (NCT03852004)
- Testing
- ostheopathy, simulated osteopathic treatment
- Where
- 2 sites in France
- Volunteers
- 40 people
- Sponsor
- Centre Hospitalier Intercommunal Creteil
Physical Inactivity, Cerebral Palsy
Effects of Physical Activity on Prescription (PAP) as a Health-enhancing Intervention in People With Disabilities
Physical inactivity is an increasing problem in the general population in society. However, in people with disabilities, inactivity is even more frequently reported.
- Conditions
- Physical Inactivity, Cerebral Palsy, Autism, Autism Spectrum Disorder
- Trial name
- PAP (NCT05867940)
- Testing
- Physical activity on prescription
- Where
- Sweden
- Volunteers
- 80 people
- Sponsor
- Region Skane