Clinical trials: Neurocognitive Function
Amnesia, Dementia
Magnetic Resonance Imaging for the Study of Patients With Neurological Disorders
This study is divided into two parts. The first part of the study will use MRI technology to view the brain structure of patients with neurological disorders and normal volunteers.
- Conditions
- Amnesia, Dementia, Healthy, Nervous System Disease
- Trial name
- NCT00001362
- Where
- United States
- Volunteers
- 830 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Cannabis Use, Neurocognitive Dysfunction
Prospective Evaluation on Cognitive Function and Its Associated Genetic Vulnerability in Cannabis Users
Most of the studies assessing Cannabis Use Disorder (CUD) and neurocognitive functions are cross-sectional without examining the longitudinal changes in neurocognitive function at a within-subject level with respect to the…
- Conditions
- Cannabis Use, Neurocognitive Dysfunction, Genetic Predisposition
- Trial name
- SToP-C_PeCoG (NCT04373525)
- Testing
- Genome analysis
- Where
- Hong Kong
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Disorder of Consciousness, Minimally Conscious State
Simultaneously PET/MRI in Prolonged DOC Patients
Recently introduced hybrid PET/MR scanners provide the opportunity to measure simultaneously, and in direct spatial correspondence, both metabolic demand and functional activity of the brain, hence capturing complementary…
- Conditions
- Disorder of Consciousness, Minimally Conscious State, FDG-PET, Rs-fMRI
- Trial name
- NCT04164680
- Testing
- Multimodal Neuroimaging
- Where
- China
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Hangzhou Normal University
Brain Concussion, Mild Traumatic Brain Injury
Neuromodulation and Neuroimaging in Older Children With Mild Traumatic Brain Injury
Mild traumatic brain injury (mTBI) often causes persistent motor and cognitive deficits in children resulting in functional limitations.
- Conditions
- Brain Concussion, Mild Traumatic Brain Injury, Motor Disorders, Cognitive Impairment
- Trial name
- CI-tDCS (NCT05762796)
- Testing
- tDCS in Youth with mild traumatic brain injury
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- State University of New York at Buffalo
Auditory Processing Disorders
Contribution of Functional MRI in Assessment of Auditory Processing Disorders
Auditory Processing Disorder (APD) affects 0.5-7% of the pediatric population. This disorder is responsible for a child's low hearing ability.
- Trial name
- IRMf-TTA (NCT03887182)
- Testing
- functional MRI, Automated Cortical Brainstem Auditory Evoked Potential, whole exome sequencing
- Where
- France
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Child Development, Motor Skills
Motor-Focused Exercise and Brain Development in Preschool Children
This study will test whether a structured motor-focused exercise program can improve both brain function and gross motor skills in preschool children.
- Conditions
- Child Development, Motor Skills, Neurodevelopment, Brain Function
- Trial name
- MoBraD (NCT07307742)
- Testing
- Motor-Focused Physical Education, Ordinary Physical Education
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Hunan Normal University
Mild Cognitive Impairment (MCI), Moderate Cognitive Impairment
Comparative Effects of Integrated Versus Sequential Approaches to Dual-Task Training in Elderly With Mild to Moderate Cognitive Impairment
Mild and Moderate cognitive impairment is a condition characterized by a noticeable decline in cognitive abilities, including memory and thinking skills, which is greater than expected for an individual's age but does not…
- Trial name
- nill (NCT07775079)
- Testing
- Integrated Dual-Task Training, Sequential Dual-Task Training
- Where
- Pakistan
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Shifa Tameer-e-Millat University
Cardiovascular Diseases, Respiratory Diseases
Study on Intervention Effect of Heat-related Health Risk Early Warning Digital Technology for School-age Children
This cluster randomized trial is conducted in Beijing primary schools to evaluate the efficacy of a WeChat mini-program-based high-temperature early warning intervention on the physical and cognitive health of school-age…
- Conditions
- Cardiovascular Diseases, Respiratory Diseases, Mental Health Disorders, Heat Illness
- Trial name
- NCT07643571
- Testing
- WeChat Mini-program Based Heat Health Risk Early Warning Intervention
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Centers for Disease Control and Prevention, China
Alzheimer's Disease
Effect of REST in the Alzheimer Disease Continuum
The investigators assume that REST gene polymorphism affects REST protein concentration, and REST protein concentration in peripheral blood is related to cognitive function and hippocampus.
- Trial name
- ERADC (NCT03884023)
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Dongzhimen Hospital, Beijing
Diabetes Mellitus, Type 1
Neurocognitive Performance During Hyperglycemia , and Brain Tissue Integrity in Youth With Type 1 Diabetes and in Healthy
Study population : 90 Participants. 60 with T1DM , and 30 healthy controls. T1DM patients will be recruited by research publication in diabetes mellitus forums. Baseline visit: informed consent signing.
- Trial name
- T1DM (NCT02923323)
- Testing
- MRI including DTI , EEG, CGMS, Neurocognitive tests
- Where
- Israel
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Assaf-Harofeh Medical Center
Attention Deficit Disorder With Hyperactivity (ADHD), Attention Deficit Disorder (ADD)
A Quick and Reliable Eye Movement Test to Help Diagnose ADHD in Children.
Attention Deficit Hyperactivity Disorder (ADHD) affects more than 5 % of children and adolescents, with a globally increasing prevalence.
- Trial name
- ADHDin15? (NCT07136259)
- Where
- Switzerland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Onovis Augenpraxis
Retinoblastoma, Neurocognitive Dysfunction
Cognitive Functioning and Health Related Quality of Life in Retinoblastoma Survivors
A retrospective crosssectional observational study of the effects of oncological treatment and frequent general anesthesia on neuropsychological development, psychosocial functioning (in terms of anxiety, depression, peer…
- Conditions
- Retinoblastoma, Neurocognitive Dysfunction, Health-Related Behavior
- Trial name
- RbNeuroQoL (NCT06227962)
- Testing
- Neuropsychological assesment, Psychosocial functioning and quality of life (questionnaires), Parental psychosocial functioning (questionnaires)
- Where
- Netherlands
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Amsterdam University Medical Center
Attention Deficit Hyperactivity Disorder, Autism Spectrum Disorder
Clinical, Environmental, Neurocognitive, Brain Imaging, and Genetic Validity of Autism and ADHD
The behavioral patterns, neurocognitive and social impairments, and high heritability are the common characteristics of autism spectrum disorders (ASD) and attention-deficit hyperactivity disorder (ADHD), the two most common…
- Trial name
- NCT00916851
- Where
- Taiwan
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Alzheimer's Disease, Healthy
The Effect of Acetylcholine on Memory and Attention
This study will examine whether enhancing the chemical acetylcholine in the brain can improve memory and attention. It will identify changes in brain function that occur during these cognitive tasks.
- Trial name
- NCT00001977
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Athlete Assessment, Archery
Validity and Test-Retest Reliability of Reactive Neurocognitive Upper Extremity Tests in Archers
In archery, the evaluation of reaction time and neurocognitive functions plays a critical role in the management of upper extremity (UE) injuries and return-to-play (RTP) processes.
- Conditions
- Athlete Assessment, Archery, Neurocognitive Functional Performance Tests
- Trial name
- NCT07103824
- Testing
- Upper Extremity Neurocognitive Tests
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Balikesir University
Cognitive Impairment, Covid19
The MentalPlus® for Assessment and Rehabilitation of Cognitive Function After Remission of the Symptoms of COVID-19
This study evaluates and rehabilitates the cognitive functions of attention, memory, visual perception, language, and executive by the mentalPlus® digital game of COVID-19 surviving patients after remission of symptoms.
- Conditions
- Cognitive Impairment, Covid19, Cognitive Dysfunction, Depression, Anxiety
- Trial name
- MP-COVID (NCT04632719)
- Testing
- The use of the MentalPlus® digital game for assessment and rehabilitation of cognitive function after remission of the symptoms of COVID-19
- Where
- 2 sites in Brazil
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Major Injury
Perioperative Research Into Memory: Cognitive Outcome Following Major Burns
The long term survival of patients who require admission to critical care (CC) following a major burn injury (MBI) continues to improve with advanced clinical management.
- Trial name
- PRiMe (NCT03470844)
- Testing
- Face-to-face neurocognitive tests, Psychological screening, fMRI
- Where
- United Kingdom
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Chelsea and Westminster NHS Foundation Trust
Diabetes Mellitus, Type 1, Diabetes
Insulin Deprivation on Brain Structure and Function in Humans With Type 1 Diabetes
What are the effects of transient insulin deprivation on brain structure, blood flow, mitochondrial function, and cognitive function in T1DM patients? What are the effects of transient insulin deprivation on circulating exosomes…
- Conditions
- Diabetes Mellitus, Type 1, Diabetes, Diabetes Complications
- Trial name
- NCT03392441
- Testing
- Insulin Deprivation in Type 1 Diabetic Patients
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Central Fatigue, Altitude Training
Effect of Hot Spring Therapy on Central Fatigue Elimination During Altitude Training
This randomized controlled trial investigates the effects of hot spring balneotherapy on central fatigue elimination in adolescent rowers undergoing altitude training at approximately 1600 meters (Tengchong, Yunnan).
- Conditions
- Central Fatigue, Altitude Training, Cognitive Impairment, Hydrotherapy
- Trial name
- HSCF-AHT (NCT07615478)
- Testing
- Natural recovery, Hot water immersion, Hot spring balneotherapy
- Where
- China
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Macao Polytechnic University
Intracranial Central Nervous System Disorder, Mental Disorder
Test of A Model of Representational Knowledge Stored in the Human Prefrontal Cortex
This study will examine the underlying mental processes that determine how people understand social behavior, remember information, and think.
- Conditions
- Intracranial Central Nervous System Disorder, Mental Disorder, Healthy
- Trial name
- NCT00024908
- Where
- United States
- Volunteers
- 949 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)