Clinical trials: Lung Recruitment
Undergoing Surgery, Perioperatif Atelectasis
Effect of Ultrasound-assisted Lung Recruitment Maneuver on Preventing Perioperative Atelectasis
This study is based on the hypothesis that recruitment maneuver reduces perioperative atelectasis and associated complications, and lung ultrasonography can be used to detect this.
- Trial name
- NCT06770179
- Testing
- recruitment maneuver, positional recruitment maneuver
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Atelectasis
Lung Recruitment Assessment With Lung Ultrasound In Pediatric Patient Scheduled For Laparoscopic Surgery
Anesthesia-induced atelectasis is a well-known entity observed in approximately 68-100% of pediatric patients undergoing general anesthesia.
- Trial name
- NCT02824146
- Testing
- Lung recruitment maneuver
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Hospital Privado de Comunidad de Mar del Plata
Respiratory Distress Syndrome in Premature Infant
Pressure HIgh or LOw DElivered to Preterm Newborns in the Delivery ROOM
The aim of this randomized pilot clinical trial of preterm infants requiring noninvasive respiratory support for respiratory distress syndrome (RDS) at birth is to improve short-term respiratory outcomes.
- Trial name
- PHILODENDROOM (NCT06123845)
- Testing
- static CPAP 8 cmH2O, static CPAP 5 cmH2O
- Where
- Italy
- Volunteers
- 56 people
- Sponsor
- ASST Fatebenefratelli Sacco
Duchenne Muscular Dystrophy
Stacking Exercises Aid the Decline in FVC and Sick Time
Duchenne Muscular Dystrophy is complicated by weak breathing muscles and lung infections. "Lung volume recruitment" is a technique performed using a face mask or mouthpiece and a hand-held resuscitation bag to stack breaths…
- Trial name
- STEADFAST (NCT01999075)
- Testing
- Lung Volume Recruitment (LVR), Conventional Treatment
- Where
- 9 sites in Canada
- Volunteers
- 70 people
- Sponsor
- Children's Hospital of Eastern Ontario
Heart Transplant Failure, Anesthesia
Impact of Atelectasis on RVEDP Following Orthotropic Heart Transplantation
Following orthoptopic heart transplantation (OHT), children undergo surveillance cardiac catheterizations to assess for signs of rejection including muscle biopsy as well as pressure measurements to guide post transplant…
- Trial name
- NCT06140810
- Testing
- Lung Recruitment
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Baylor College of Medicine
Prematurity, Respiratory Distress Syndrome,Hypoxemia
Follow-up at School-age of Children Who Participated in the Efficacy Study of Nitric Oxide for Premature Infants
Our previous data demonstrated that premature infants treated with inhaled nitric oxide at birth had improved neurodevelopmental outcomes at two years corrected age.
- Trial name
- NCT00152542
- Testing
- Inhaled nitric oxide
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- University of Chicago
Anesthesia, Intravenous Fluid
Lung Recruitment Maneuver as a Potential Predictor of Fluid Responsiveness in Mechanically Ventilated Pediatric Patients
In this research study we want to learn more about using non-invasive tools as a way to predict whether or not a child under general anesthesia will require and respond to fluid administration.
- Conditions
- Anesthesia, Intravenous Fluid, Blood Pressure
- Trial name
- NCT03431064
- Testing
- Lung Recruitment Maneuver, Fluid Administration
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Boston Children's Hospital
Atelectasis
The Effect of Lung Recruitment Maneuver on Postoperative Atelectasis in Children
The investigators compare the degree of atelectasis in recovery room between conventional recruitment maneuver and ultrasonography-guided lung recruitment during surgery.
- Trial name
- NCT03453762
- Testing
- recruitment maneuver, ultrasonography-guided recruitment maneuver
- Where
- South Korea
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Anesthesia
Lung Recruitment and Postoperative CPAP
General anesthesia lowers FRC thereby promoting airway closure and absorption atelectasis. Alveolar recruitment manoeuvers recruit collapsed alveoli, increase gas exchange, and improve arterial oxygenation.
- Trial name
- LRvsCPAP (NCT02502279)
- Testing
- Engström Datex-Ohmeda ICU Ventilator, Postoperative CPAP mask
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Asthma
Registry of Asthma Characterization and Recruitment 3 (RACR3)
This is a multi-center, non-interventional registry to create and maintain a database of participants to serve as a recruitment source for current and future DAIT NIAID-sponsored Childhood Asthma in Urban Settings (CAUSE) studies.
- Trial name
- RACR3 (NCT05272241)
- Where
- 7 sites in United States
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
ARDS, Pediatric Respiratory Distress Syndrome
REcruitment MAneuvers and Mechanical Ventilation Guided by EIT in pARDS
There is evidence from randomized controlled trials in adult patients with Acute Respiratory Distress Syndrome (ARDS) suggesting that delivering small tidal volumes with adequate levels of Positive End-Expiratory Pressure (PEEP)…
- Conditions
- ARDS, Pediatric Respiratory Distress Syndrome, Respiratory Disease
- Trial name
- REMAV-EIT (NCT06067152)
- Testing
- EIT measurement, Staircase Recruitment Maneuvers with EIT guided and decremental PEEP trial, Setting of EIT-guided mechanical ventilation
- Where
- Italy
- Volunteers
- 13 people
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Acute Respiratory Distress Syndrome
Open Lung Ventilation in ARDS: The PHARLAP Trial
Some people develop the condition called acute respiratory distress syndrome (ARDS). This is a condition where the lungs have become injured from one of a number of various causes, and do not work as they normally do to provide…
- Trial name
- PHARLAP (NCT01667146)
- Testing
- PHARLAP mechanical ventilation strategy, Control group mechanical ventilation strategy
- Where
- 27 sites in Australia, Ireland and 3 more
- Volunteers
- 115 people
- Sponsor
- Australian and New Zealand Intensive Care Research Centre
Hypovolemia
Lung Recruitment Maneuver for Predicting Fluid Responsiveness in Children
Lung recruitment maneuver induces a decrease in stroke volume, which is more pronounced in hypovolemic patients. The authors hypothesized that the changes of dynamic variables through lung recruitment maneuver could predict…
- Trial name
- NCT03184961
- Testing
- lung recruitment maneuver
- Where
- South Korea
- Volunteers
- 30 people
- Sponsor
- Seoul National University Hospital
PreTerm Neonate, Positive End Expiratory Pressure (PEEP)
PEEP FOR LUNG RECRUITMENT IN PRETERM INFANTS-EIT STUDY
Babies born early (under 32 weeks) are at risk of developing lung problems after birth. A major reason for this is that the lungs are not fully developed.
- Conditions
- PreTerm Neonate, Positive End Expiratory Pressure (PEEP), Lung Recruitment, Electrical Impedance Tomography (EIT)
- Trial name
- [PEOPLE] (NCT06705257)
- Testing
- Studying the effects of varying levels of PEEP using Electrical impedance tomography
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- South Tees Hospitals NHS Foundation Trust
Surfactant Deficiency Syndrome Neonatal
deMISTify: The Impact of Ventilator Pressure Levels During Minimally Invasive Surfactant Therapy on Lung Aeration in Preterm Infants
Infants born preterm (before 36 weeks' gestation age) have immature lungs and struggle to breathe on their own. They are supported via respiratory machines like ventilators, as well as pharmaceutical aids like surfactant…
- Trial name
- deMISTify (NCT07522346)
- Testing
- Lung Recruitment Manoeuvre prior to Minimally Invasive Surfactant Therapy, Control (Minimally Invasive Surfactant Therapy)
- Where
- Australia
- Volunteers
- 36 people
- Sponsor
- Murdoch Childrens Research Institute
Anesthesia Induced Atelectasis
Evaluation of the Effect of Lung Recruitment and Positive End- Expiratory Pressure (PEEP) on Anesthesia Induced Atelectasis Using Lung Ultrasound
Atelectasis is a side effect of general anesthesia which can be found in all types of interventions and patients of all ages.1-3 The reported incidence of anesthesia- induced atelectasis in children varies, ranging from 12 to 42%…
- Trial name
- NCT03069157
- Testing
- lung recruitment maneuver
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Kasr El Aini Hospital
Pulmonary Atelectasis, Postoperative, Atelectasis, Compression
Postoperative Atelectasis in Pediatric Patients With Prone Position
This study evaluates the incidence of postoperative atelectasis after general anesthesia with prone position using lung ultrasound in children age < 3 years.
- Trial name
- NCT03486847
- Testing
- Repetitive recruitment with PEEP, One recruitment with PEEP
- Where
- South Korea
- Volunteers
- 74 people
- Sponsor
- Seoul National University Hospital
Asthma
Registry for Asthma Characterization and Recruitment 2
There is a need for people to take part in research studies to learn more about diseases and how to treat them. The Registry for Asthma Characterization and Recruitment 2 (RACR2) will create a database of participants with asthma…
- Trial name
- RACR2 (NCT02513264)
- Where
- 10 sites in United States
- Volunteers
- 1,384 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Asthma, Chronic Obstructive Pulmonary Disease
Asthma & COPD Guideline Implementation
This is a report of a protocol developed to improve asthma and COPD care in a primary care setting. The study was approved by an Ethics Committee and support by the Canadian Thoracic Society through an unrestrictive grant from…
- Trial name
- NCT01766544
- Testing
- Standard Practice Group (SPG), TISG
- Where
- Canada
- Volunteers
- 92 people
- Sponsor
- Laval University
Acute Respiratory Distress Syndrome
PEEP Recruitment-comparison Between Ultrasonographic Assessment and LIP Assessment
The purpose of this study is to compare lung recruitment in acute lung injury (ALI)/acute respiratory distress syndrome (ARDS) based on lower inflection point with transthoracic ultrasonographic assessment of lung recruitment.
- Trial name
- NCT01478217
- Where
- Croatia
- Volunteers
- 17 people
- Sponsor
- Sisters of Mercy University Hospital