Clinical trials: Liver Transplant Surgery
Liver Resection, Liver Tumours
Evaluation Of Liver Resection Using Harmonic Scalpel Versus Cavitron Ultrasonic Surgical Aspirator (CUSA).
Evaluation Of Liver Resection Using Harmonic Scalpel Versus Cavitron Ultrasonic Surgical Aspirator (CUSA) Introduction The mode of parenchymal transection in hepatic resection has been a topic of great debate for decades.
- Conditions
- Liver Resection, Liver Tumours, Liver Transplant Disorder, Trauma Abdomen
- Trial name
- NCT07142876
- Testing
- Liver resection Cavitron Ultrasonic Surgical Aspirator (CUSA), Liver resection with the harmonic scalpel
- Volunteers
- 50 people
- Sponsor
- Sohag University
Liver Cirrhosis, Biliary
Autologous Bone Marrow Mononuclear Stem Cell for Children Suffering From Liver Cirrhosis Due to Biliary Atresia
The aim of this study was to evaluate the safety and effectiveness of autologous bone marrow mononuclear stem cell transplantation for Children Suffering from Liver Cirrhosis Due to Biliary Atresia
- Trial name
- NCT03468699
- Testing
- Autologous BMMC transplantation
- Where
- 2 sites in Vietnam
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Vinmec Research Institute of Stem Cell and Gene Technology
Liver Diseases
TachoSil Paediatric Liver Trial (TC-019-IN)
The overall objective is to assess the haemostatic efficacy and safety of TachoSil for control of local bleeding in paediatric patients undergoing surgical resection of the liver with our without segmental liver transplantation.
- Trial name
- NCT00365248
- Testing
- Fibrinogen human (TachoSil)
- Where
- Denmark
- Volunteers
- 16 people
- Sponsor
- Nycomed
Liver Transplant, Erector Spina Plan Block
Perioperative Analgesia With Erector Spinae Plane Block in Liver Transplant Recipients
The goal of this clinical trial is to learn if ESP block is safe and effective for perioperative analgesia in patients undergoing liver transplant.
- Trial name
- NCT06857331
- Testing
- Erector Spinae Plane Block using 0.2% ropivacaine
- Where
- Ukraine
- Volunteers
- 50 people
- Sponsor
- Bogomolets National Medical University
Liver Diseases, Liver Cirrhosis
Intraoperative Phlebotomies and Bleeding in Liver Transplantation
Liver transplantation are surgeries associated with important bleeding and often require perioperative red blood cell (RBC) transfusions.
- Conditions
- Liver Diseases, Liver Cirrhosis, Surgery, Surgery--Complications
- Trial name
- TOF_PHLEBO (NCT04826666)
- Where
- Canada
- Volunteers
- 679 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Biliary Stricture
Fully Covered Self-expandable Metal Stents (FCMS) in Benign Biliary Strictures
Endoscopic treatment of benign biliary strictures can be challenging. Balloon dilation and/or plastic stent placement are currently the most popular techniques.
- Trial name
- NCT02105181
- Testing
- Placement of a FCMS in the biliary tract of the patients
- Where
- France
- Volunteers
- 92 people
- Sponsor
- Société Française d'Endoscopie Digestive
Liver Failure, Liver Diseases
Intraoperative Hemodynamic Management and Postoperative Outcomes in Liver Transplantation
The overarching objective of the research program entitled ELIPTO (Enhancing Liver Insufficiency and Postoperative Transplantation Outcomes) (www.elipto.ca) is to improve the perioperative care of liver transplant recipients.
- Conditions
- Liver Failure, Liver Diseases, Surgery, Surgery--Complications
- Trial name
- ELIPTO-2 (NCT04732689)
- Where
- Canada
- Volunteers
- 852 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
ABO Incompatibility, Liver Transplant Surgery
Study on the Clinical Outcomes of ABO-Incompatible Living Donor Liver Transplantation
Evaluate the postoperative survival rate and incidence of rejection in patients undergoing ABO-incompatible living donor liver transplantation; analyze the occurrence of secondary endpoint events such as postoperative vascular…
- Conditions
- ABO Incompatibility, Liver Transplant Surgery, Living Donor Liver Transplantation
- Trial name
- NCT07273448
- Volunteers
- 100 people
- Sponsor
- Zhi-Jun Zhu
Primary Biliary Cirrhosis
Umbilical Cord Derived Mesenchymal Stem Cell (UC -MSC) Transplantation for Children Suffering From Biliary Atresia
Biliary atresia (BA) is the most frequent cause of chronic cholestasis in neonates, accounting for at least 50% of pediatric liver transplantation. BA incidence is estimated to range from 1:5000 to 1:19000 live births.
- Trial name
- UCMSCBA (NCT04522869)
- Testing
- Umbilical Cord Derived Mesenchymal Stem Cell (UC -MSC) Transplantation
- Where
- 2 sites in Vietnam
- Volunteers
- 20 people
- Sponsor
- Vinmec Research Institute of Stem Cell and Gene Technology
Biliary Atresia, Kasai Portoenterostomy
Clinical Outcomes of Early Kasai Surgery With Umbilical Cord MSCs in Biliary Atresia
The goal of this clinical trial with historical control is to evaluate whether umbilical cord-derived mesenchymal stem cell (UC-MSC) therapy can improve clinical outcomes in infants with biliary atresia undergoing Kasai surgery…
- Conditions
- Biliary Atresia, Kasai Portoenterostomy, Mesenchymal Stem Cell Transplantation, Liver Function Disorders
- Trial name
- NCT07011199
- Testing
- Umbilical Cord-Derived Mesenchymal Stem Cells (UC-MSCs), Kasai Portoenterostomy
- Where
- Indonesia
- Volunteers
- 14 people
- Sponsor
- Universitas Diponegoro
Liver Transplantation
Application of in Vivo Splitting Technique in Adult Liver Transplantation
The feasibility of split liver transplantation (SLT) remains controversial. This study aimed to evaluate the outcomes of SLT in adult recipients and to identify specific areas of improvements.
- Trial name
- NCT06925828
- Testing
- No intervention
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Ningbo Medical Center Lihuili Hospital
Pediatric Liver Transplanted Recipients, Healthy Donors
Living Donor Liver Transplantation in Children
Evaluate the outcome of pediatric living donor liver transplantation (LDLT) regarding portal vein reconstruction, ABO-compatibility and impact of maternal donation on graft acceptance.
- Trial name
- NCT02124382
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Hemorrhage
TachoSil® Versus Surgicel® Original for the Secondary Treatment of Local Bleeding in Adult and Pediatric Patients Undergoing Hepatic Resection Surgery
The efficacy and safety of TachoSil® as secondary hemostatic treatment in hepatic resection surgery will be compared to the standard USA licensed hemostatic agent, Surgicel® Original.
- Trial name
- NCT01192022
- Testing
- TachoSil®, Surgicel® Original
- Where
- 17 sites in United States
- Volunteers
- 253 people
- Sponsor
- Takeda
Progressive Familial Intrahepatic Cholestasis
NAtural Course and Prognosis of PFIC and Effect of Biliary Diversion
The natural course of PFIC syndromes and the effect of diversion techniques, have so far not been characterized in a rigorous manner within a larger population of patients.
- Trial name
- NAPPED (NCT03930810)
- Testing
- Surgical biliary diversion
- Where
- Netherlands
- Volunteers
- 1,500 people
- Sponsor
- University Medical Center Groningen