Clinical trials: Knowledge Translation
Acute Coronary Syndromes
Knowledge Translation for Patients With Acute Coronary Syndromes
Cluster randomized open-label experimental study multi-center of 24 hospitals to either knowledge translation vs usual care to improve care of patents hospitalized for acute coronary syndromes.
- Trial name
- AMI-OPTIMA (NCT02672137)
- Testing
- knowledge translation
- Volunteers
- 4,604 people
- Sponsor
- Montreal General Hospital
Use of Research Evidence
Effects of an Evidence Service on Community-based AIDS Service Organizations' Use of Research Evidence
The investigators have developed an online database called 'Synthesized HIV/AIDS Research Evidence' (SHARE), which is designed to support the use of research evidence by those working in the HIV/AIDS sector.
- Trial name
- NCT01257724
- Testing
- SHARE (Synthesized HIV/AIDS Research Evidence)
- Where
- Canada
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Ontario HIV Treatment Network
Osteoporosis
Vitamin D Osteoporosis Long-Term Care Study
The research question is, does a multifaceted, multidisciplinary intervention including small groups, chart audits and point of care tools, increase the number of people receiving optimal vitamin D therapy in the long term care…
- Trial name
- ViDOS (NCT01398527)
- Testing
- Educ sessions & LTC Osteoporosis toolkit
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- McMaster University
Croup
A Cluster Controlled Trial Comparing Three Methods of Disseminating Practice Guidelines for Children With Croup
The purpose of this study is to identify, from a societal perspective, the costs and associated benefits of three strategies for disseminating and implementing a practice guideline that addresses the management of croup.
- Trial name
- NCT00147849
- Testing
- mailing of printed educational materials, a combination of interactive educational meetings, educational outreach visits, and reminders, identification of local opinion leaders and establishment of local consensus processes
- Sponsor
- Canadian Institutes of Health Research (CIHR)
Infectious Disease, Cardiovascular Disease
Promoting Evidence-Based Decision-Making in India: District Evaluation Study on Health
The purpose of this study is to assess the impact of disseminating information on comparative performance, along with actionable messages on how to improve health outcomes, to district-level decision-makers in India using a…
- Trial name
- DESH (NCT01003587)
- Testing
- District health information package
- Where
- 2 sites in Canada, India
- Volunteers
- 594 people
- Sponsor
- Unity Health Toronto
Procedural Pain
Parent Targeted Interventions in Vaccination Pain Management of Infants
The overall aim of this study is to investigate the feasibility, acceptability, preliminary effectiveness and sustainability of parent-targeted interventions for pain management during vaccination of infants.
- Trial name
- NCT03968432
- Testing
- MIAS&Q, Be Sweet to Babies Videos and Pamphlet
- Where
- Canada
- Volunteers
- 151 people, healthy volunteers welcome
- Sponsor
- University of Ottawa
Traumatic Brain Injury
Traumatic Brain Injury - Knowledge Translation
Blunt head trauma (BHT) accounts for >450,000 emergency department (ED) visits for children annually in the US. Fortunately, >95% of head trauma in children is minor in nature.
- Trial name
- TBI-KT (NCT01453621)
- Testing
- Computerized clinical decision support
- Where
- United States
- Volunteers
- 28,669 people
- Sponsor
- Columbia University
Eating Disorders in Adolescence, Transition of Care
Feasibility of the TransitionED Framework for Youth and Young Adults With Eating Disorders
Moving from pediatric (children's) health care to adult health care can be challenging for youth and young adults with eating disorders.
- Trial name
- TransitionED 3 (NCT07518641)
- Testing
- TransitionED Healthcare Transition Framework
- Where
- 2 sites in Canada
- Volunteers
- 60 people
- Sponsor
- McMaster University
Pain
Caring for Babies During the Newborn Screening Blood Test
Newborn infants have blood work procedures in their first days of life that cause pain, distress and physiological changes. Breastfeeding (BF), skin to skin care (SSC), or giving sweet solutions (sucrose or glucose) has been…
- Trial name
- NCT02608892
- Testing
- BSweet2Babies video
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Eastern Ontario
Fracture, Fractures, Hip
The PREVENT Trial: a Pragmatic Cluster Randomized Controlled Trial of a Multifaceted Fracture Prevention Model for Long-term Care
Hip fractures occur nearly twice as often for older adults residing in long-term care as they do in older adults of a similar age still living in other settings.
- Conditions
- Fracture, Fractures, Hip, Osteoporosis
- Trial name
- PREVENT (NCT04947722)
- Testing
- PREVENT Program
- Where
- Canada
- Volunteers
- 3,060 people, healthy volunteers welcome
- Sponsor
- McMaster University
Cardiac Arrest
The Strategies for Post Arrest Resuscitation and Care Network
Background: One of the 2010 Impact Goals of the Emergency Cardiac Care (ECC) Committee of the American Heart Association is to double survival from cardiac arrest.
- Trial name
- SPARC (NCT00683683)
- Testing
- Knowledge Translation
- Volunteers
- 32 people
- Sponsor
- Unity Health Toronto
Chronic Diseases
A Cluster-randomized Controlled Knowledge Translation Feasibility Study in Alberta Community Pharmacies
Background: Despite evidence of benefit for pharmacist involvement in chronic disease management, the provision of these services in community pharmacy has been suboptimal.
- Trial name
- NCT02191111
- Testing
- Task-focused facilitation
- Where
- Canada
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Physicians Evidence Retrieval Skills
Multifaceted Online Interventions to Increase Clinicians Searching of Current Best Evidence to Answer Clinical Questions
Translation of new knowledge from research into evidence-informed health care is a shared obligation of the clinical and the scientific communities.
- Trial name
- MPFS (NCT02038439)
- Testing
- Intervention A - Online Clinical Questions Recorder, Intervention B - Online Evidence Retrieval Coach, Intervention C - Online Audit and Feedback
- Where
- Canada
- Volunteers
- 908 people
- Sponsor
- McMaster University
Healthy Volunteer
OrthoEvidence Trial Assessing Japanese Knowledge Updates
The purpose of this randomized controlled trial is to clarify whether providing translated evidence summary (Advanced Clinical Evidence (ACE) reports from OrthoEvidence) will increase the access to the summary compared to…
- Trial name
- OTAKU (NCT05250622)
- Testing
- Japanese-translated evidence summaries (Advanced Clinical Evidence report from OrthoEvidence), English evidence summaries (Advanced Clinical Evidence report from OrthoEvidence)
- Where
- Canada
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- McMaster University
Acute Gastroenteritis, Pediatric ALL
Evaluating a Knowledge Translation Tool for Parents
Diarrhea and vomiting in children is a common reason to visit the emergency department. There has been a lot of research on how best to treat children with diarrhea and vomiting who visit the emergency department; however, the…
- Conditions
- Acute Gastroenteritis, Pediatric ALL, Knowledge Translation
- Trial name
- NCT03234777
- Testing
- Whiteboard animation video, Regular video
- Where
- Canada
- Volunteers
- 56 people
- Sponsor
- University of Alberta
Asthma, Chronic Obstructive Pulmonary Disease
Asthma & COPD Guideline Implementation
This is a report of a protocol developed to improve asthma and COPD care in a primary care setting. The study was approved by an Ethics Committee and support by the Canadian Thoracic Society through an unrestrictive grant from…
- Trial name
- NCT01766544
- Testing
- Standard Practice Group (SPG), TISG
- Where
- Canada
- Volunteers
- 92 people
- Sponsor
- Laval University
Pain
Sustainability of a Knowledge Translation Intervention to Improve Paediatric Pain
The purpose of this research study is to evaluate the effectiveness of short refresher sessions. "Pain Practice Change Boosters" given at regular intervals to sustain improved pain process (assessment and management) and clinical…
- Trial name
- NCT02236949
- Testing
- Pain Practice Change Booster Intervention
- Where
- 7 sites in Canada
- Volunteers
- 3,907 people, healthy volunteers welcome
- Sponsor
- The Hospital for Sick Children
Asthma, Diarrhea & Vomiting
Best Strategies for Implementation of Clinical Pathways in Emergency Department Settings
An Ontario-wide study to identify best strategies to promote uptake of high quality, expert developed Clinical Pathways (CPs) within Emergency Departments.
- Trial name
- NCT01815710
- Testing
- Pediatric Asthma Clinical Pathway, Vomiting & Diarrhea Pathway
- Where
- Canada
- Volunteers
- 6,330 people
- Sponsor
- Children's Hospital of Eastern Ontario
Atrial Fibrillation, Stroke
Canadian Community Utilization of Stroke Prevention Study - Emergency Department
Atrial fibrillation (AF) is a common heart condition, and increases the risk of stroke by six times. There are several medications (blood thinners) that can prevent strokes in AF patients.
- Trial name
- C-CUSP ED (NCT02358655)
- Testing
- Retrospective review of OAC prescription, Prescription of OAC in ED, Community AF clinic
- Where
- 5 sites in Canada
- Volunteers
- 360 people
- Sponsor
- Population Health Research Institute
Trauma
The WikiTrauma Interrupted Time Series Protocol
The purpose of this study is to study the combined effect of WikiTrauma, a free collaborative database of clinical decision support tools, and Wiki101, a training course teaching participants how to use WikiTrauma, on the quality…
- Trial name
- WikiTrauma (NCT04035772)
- Testing
- Wiki101 and WikiTrauma
- Where
- Canada
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Laval University